Risk of Epilepsy in Individuals With Posttraumatic Stress Disorder: A Nationwide Longitudinal Study
Objective: Several cross-sectional studies have reported a relationship between posttraumatic stress disorder (PTSD) and epilepsy. However, the temporal association between PTSD and epilepsy has rarely been investigated. We hypothesized that the risk of developing epilepsy later in life would be higher in patients with PTSD than in those without PTSD. Methods: Using the Taiwan National Health Insurance Research Database, 6425 individuals with PTSD and 24,980 age-/sex-matched controls were enrolled between 2002 and 2009 in our study and followed up to the end of 2011. Those who developed epilepsy during the follow-up perio...
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Posttraumatic Stress Disorder, Orientation to Pain, and Pain Perception in Ex-Prisoners of War Who Underwent Torture
This study examined whether chronic pain and pain perception among torture survivors are associated with torture experience or PTSD and whether catastrophic and fearful orientations mediate or moderate these associations. Methods: Fifty-nine ex-prisoners of war who underwent torture and 44 matched veterans participated in this study. Pain perception was evaluated by assessing pain threshold and reactivity to experimental suprathreshold noxious stimuli. Participants completed self-administered questionnaires assessing PTSD, chronic pain, pain catastrophizing, and fear of pain. Results: Although chronic pain was associated...
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Genetic and Environmental Influences on Sleep, Pain, and Depression Symptoms in a Community Sample of Twins
Conclusions: The link between sleep quality, pain, and depression was primarily explained by shared genetic influences. The genetic factors influencing sleep quality and pain were highly correlated even when accounting for depression. Findings support the hypothesis of a genetic link between depression and pain as well as potential causality for the association of sleep quality with pain and depression. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Relationship Between Mental Health, Disease Severity, and Genetic Risk for Depression in Early Rheumatoid Arthritis
Objective: Reduced mental health (MH) is prevalent in rheumatoid arthritis (RA). Although longitudinal studies are limited, there is evidence that depression is associated with worse disease outcomes. We evaluated reciprocal relationships between MH, RA severity, and genetic risks for depression for 2 years in a well-characterized cohort of RA patients. Methods: We evaluated 520 early RA patients previously enrolled to two clinical trials. MH was measured using the short form-36 MH domain and mental component summary scores (MCS). MCS/MH associations over 2 years with disease activity (disease activity score on a 28-joint...
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Joint Impact of Early Life Adversity and COMT Val158Met (rs4680) Genotypes on the Adult Cortisol Response to Psychological Stress
Conclusions: Met/Met homozygotes seem sensitive to stressful events in childhood and adolescence, leading to environmental programming of the stress axis. Glucocorticoid responsivity may represent a common pathway revealing targeted genetic vulnerabilities to the long-term effects of early life stress. The results suggest that further G × E studies of ELA are warranted in relation to health behaviors and health outcomes in adulthood. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Associations of Lifetime Trauma and Chronic Stress With C-reactive Protein in Adults Ages 50 Years and Older: Examining the Moderating Role of Perceived Control
Objective: The aim of the study was to investigate whether high perceived control mitigates systemic inflammatory risk associated with traumatic and chronic stress exposures in older adults. Methods: A sample of community-dwelling adults ages 50 years and older (N = 4779) was drawn from the Health and Retirement Study. Structural equation models tested interactions of lifetime trauma and chronic stress with mastery and perceived constraints predicting baseline levels and 4-year change in C-reactive protein (CRP). Results: There were significant interactions of lifetime trauma (β = −.058, p = .012) and chronic ...
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Vagal Regulation of Cardiac Function in Early Childhood and Cardiovascular Risk in Adolescence
Conclusions: Vagal regulation of cardiac function in early childhood predicts select indicators of cardiovascular risk 14 years later. Early signs of attenuated vagal regulation could indicate an increased risk for elevated blood pressure before adulthood. Future research should test biological, behavioral, and psychological mechanisms underlying these long-term predictions. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Article Summaries for July–August 2017 Psychosomatic Medicine, Volume 79, Issue 6
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 30, 2017 Category: Psychiatry & Psychology Tags: In This Issue Source Type: research

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Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
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Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
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Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover.
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Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

Diabetes Complications and Depressive Symptoms: Prospective Results From the Montreal Diabetes Health and Well-Being Study
Objective: Prospective studies testing the potential impact of diabetes complications on depression are limited. The present study examined the longitudinal associations between diabetes complications and the risk and recurrence/persistence of depressive symptoms. Methods: Data were from a prospective community cohort telephone survey of adults with diabetes (N = 1314). Diabetes complications and depressive symptoms were assessed via self-report (Diabetes Complications Index and Patient Health Questionnaire-9, respectively) at baseline and annually for 5 years. Statistical models adjusted for sociodemographic, lifestyle, ...
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Double Exposure to Adverse Psychosocial Work Factors and High Family Responsibilities as Related to Ambulatory Blood Pressure at Work: A 5-Year Prospective Study in Women With White-Collar Jobs
Conclusions: A double exposure to effort-reward imbalance at work and high family responsibilities might contribute to elevated ambulatory BP at work among women. BP elevations related to this double exposure may persist for several years. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Stress, Illness Perceptions, Behaviors, and Healing in Venous Leg Ulcers: Findings From a Prospective Observational Study
Conclusions: Alongside ulcer-related predictors, psychological and sociodemographic factors were associated with healing. Future research should explore mediating mechanisms underlying these associations and develop interventions to target these variables. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Impact of Panic Attacks on Bronchoconstriction and Subjective Distress in Asthma Patients With and Without Panic Disorder
This study evaluated the impact of panic attacks (PAs) on bronchoconstriction and subjective distress in people who have asthma with and without PD. Methods: A total of 25 asthma patients (15 with PD who had a PA [PD/PA], 10 without PD who did not have a PA [no PD/no PA]) were recruited from an outpatient clinic. They underwent a panic challenge (one vital capacity inhalation of 35% carbon dioxide [CO2]) and completed the Panic Symptom Scale, the Subjective Distress Visual Analogue Scale, and the Borg Scale before and after CO2. Forced expiratory volume in 1 second was assessed pre- and post-CO2; respiratory (i.e., CO2 pr...
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Impact of Subjective Well-being on Mortality: A Meta-Analysis of Longitudinal Studies in the General Population
Conclusions: Our results suggest that subjective well-being is associated with a decreased risk of mortality. Longitudinal studies examining changing levels of well-being and their relationship to longevity would be required to establish a cause–effect relationship. Establishing such a causal relationship would strengthen the case for policy interventions to improve the population subjective well-being to produce longevity gains combined with optimizing quality of life. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Systematic Review/Meta-Analysis Source Type: research

The Prospective Association of the Diurnal Cortisol Rhythm With Sleep Duration and Perceived Sleeping Problems in Preschoolers: The Generation R Study
Conclusions: The present study suggests that a flatter diurnal cortisol slope and a more marked morning rise, which can indicate stress (or hypothalamic-pituitary-adrenal dysregulation), have a long-term association with sleep regulation. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Omega-3 Supplementation and the Neural Correlates of Negative Affect and Impulsivity: A Double-Blind, Randomized, Placebo-Controlled Trial in Midlife Adults
Conclusions: In healthy adults with low intake of omega-3 fatty acids, moderate-dose supplementation for 18 weeks did not alter affect or impulsive behaviors nor alter corticolimbic and corticostriatal brain functionality. Trial Registration: Trial number NCT00663871. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Divergent Influences of Cardiovascular Disease Risk Factor Domains on Cognition and Gray and White Matter Morphology
Conclusions: Cardiovascular domains were associated with distinct cognitive, gray, and white matter alterations and distinct age groups. Future longitudinal studies may assist in identifying vulnerability profiles that may be most important for individuals with multiple cardiovascular disease risk factors. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Regional Gray Matter Volumes as Related to Psychomotor Slowing in Adults with Type 1 Diabetes
Conclusions: For middle-aged adults with T1D and cerebral microvascular disease, GMV of basal ganglia may play a critical role in regulating psychomotor speed, as measured via DSST. Studies to quantify the impact of basal ganglia atrophy concurrent with WMH progression on psychomotor slowing are warranted. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Early Life Stress, FKBP5 Polymorphisms, and Quantitative Glycemic Traits
We examined whether FKBP5 single-nucleotide polymorphisms (SNPs) interact with ELS on Type 2 diabetes, cardiovascular disease, and quantitative glycemic traits. Methods: A total of 1728 Helsinki Birth Cohort Study participants born from 1934 to 1944 were genotyped for FKBP5 SNPs (rs1360780, rs9394309, rs9470080) and were administered a 2-hour (75 g) oral glucose tolerance test and a questionnaire on physician-diagnosed and medication use for chronic diseases at a mean age of 61.5 years. Of the participants, 273 had been exposed to ELS, operationalized as separation from their parents, at a mean age of 4.7 years due to eva...
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Early-Life Socioeconomic Disadvantage and Metabolic Health Disparities
Conclusions: These findings suggest that MetS health disparities originate in childhood, which may be an opportune period for interventions. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

An Attachment-Based Model of the Relationship Between Childhood Adversity and Somatization in Children and Adults
Conclusions: Deficits in maternal sensitivity at 18 months of age are related to the emergence of somatization by age 5 years. Adult attachment insecurity is related to somatization. Insecure attachment may partially mediate the relationship between early adversity and somatization. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Trauma and Autonomic Dysregulation: Episodic—Versus Systemic—Negative Affect Underlying Cardiovascular Risk in Posttraumatic Stress Disorder
Objective: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart rate variability (HRV) in cross-sectional research. Recent evidence suggests that this link may be driven by individual differences in autonomic arousal associated with momentary negative affect (NA). Using ecological momentary assessment (EMA) of NA and minute-to-minute HR/HRV monitoring, we examined whether NA-related HR/HRV mediated the association of PTSD symptom severity with 24-hour HRV and endothelial functioning. Methods: One hundred ninety-seven young adults (18–39 years), 93 with PTSD, underwent 1 ...
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Article Summaries for June 2017 Psychosomatic Medicine, Volume 79, Issue 5
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - June 1, 2017 Category: Psychiatry & Psychology Tags: In This Issue Source Type: research

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Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
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Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover.
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Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

Abstracts of the 75th Annual Scientific Meeting, March 15-18, 2017. Sevilla, Spain.
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: MEETING ABSTRACTS: PDF Only Source Type: research

The Effects of Expressive Writing on Lung Function, Quality of Life, Medication Use, and Symptoms in Adults With Asthma: A Randomized Controlled Trial: Erratum
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Erratum Source Type: research

Assessment of Biopsychosocial Complexity and Health Care Needs: Measurement Properties of the INTERMED Self-Assessment Version
Conclusions: The IMSA is a generic and time-efficient method to assess biopsychosocial complexity and to provide guidance for multidisciplinary care trajectories in adult patients, with good reliability and validity across different cultures. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Sex Differences in the Relationship Between Depressive Symptoms and Actigraphic Assessments of Sleep and Rest-Activity Rhythms in a Population-Based Sample
Objective: Depression is often associated with disruptions in sleep and circadian rhythms. We aimed to confirm these relationships via actigraphic assessment in a large, population-based sample and test whether sex moderates these relationships. Methods: A total of 418 participants (age = 35–85 years, mean [standard deviation] = 57.04 [11.47]) completed questionnaires and 1 week of actigraphy, used to calculate sleep and rest-activity statistics including mesor (mean activity level), amplitude (height of rhythm), and acrophase (time of day that rhythm peaks). Results: Depressive symptoms, assessed via Center for Ep...
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Association Between Discrimination and Objective and Subjective Sleep Measures in the Midlife in the United States Study Adult Sample
We examined the relationship between discrimination and markers of subjective and objective sleep in a racially diverse sample. Methods: The analytic sample included 441 participants of the Midlife in the United States II (MIDUS) study (M [SD] age, 46.6 [1.03]; female, 57.9%; male, 42.1%; nonwhite, 31.7%). Complete data were available for 361 participants. Sleep measures included the Pittsburgh Sleep Quality Index, sleep latency, wake after sleep onset, and sleep efficiency derived from 7-day actigraphy. Discrimination was measured with the Williams Everyday Discrimination Scale. Ordinary least squares and logistic regres...
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Insomnia and the Risk of Breast Cancer: The HUNT Study
Conclusion: Our results suggest that having only some aspects of insomnia may not predispose someone to breast cancer. In contrast, experiencing all insomnia symptoms simultaneously might confer considerable excess risk. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Chronic Stress and C-Reactive Protein in Mothers During the First Postpartum Year
Conclusions: In this low-income and ethnic/racially diverse sample of women, higher financial stress at 1-month postbirth predicted higher CRP. Study findings suggest that perceived financial stress stemming from socioeconomic disadvantage may be a particular deleterious form of stress affecting maternal biology during the year after the birth of a child. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Child Abuse and Neglect and Subclinical Cardiovascular Disease Among Midlife Women
Objective: A childhood history of abuse or neglect may be associated with elevated adult cardiovascular disease (CVD) risk. No studies have examined associations between child abuse/neglect and subclinical CVD using a validated measure of abuse and neglect. We hypothesized that midlife women with a history of childhood abuse or neglect would have increased subclinical CVD beyond standard CVD risk factors. We tested moderation of associations by sleep, hot flashes, and race/ethnicity. Methods: Two hundred ninety-five midlife women completed the Child Trauma Questionnaire, physiologic hot flash and actigraphic sleep monitor...
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Measuring Childhood Adversity in Life Course Cardiovascular Research: A Systematic Review
Conclusions: The literature on childhood adversity and CVD would benefit from improving consistency of measurement, using weighted adversity composites, modeling adversity trajectories over time, and considering socioeconomic status as an antecedent factor instead of a component part of an adversity score. We suggest conceptual and analytic strategies to enhance, refine, and replicate the observed association between childhood adversity and CVD risk. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Systematic Review/Meta-Analysis Source Type: research

The Impact of Complicated Grief on Diurnal Cortisol Levels Two Years After Loss: A Population-Based Study
Conclusions: Participants with complicated grief showed low levels of morning cortisol and low overall diurnal cortisol levels characteristic for a chronic stress reaction. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Role of Agonistic Striving in the Association Between Cortisol and High Blood Pressure
Conclusions: Agonistic striving may represent a distinctive (and novel) social-cognitive mechanism of toxic stress and cardiovascular risk. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Validity of the European Society of Cardiology's Psychosocial Screening Interview in Patients With Coronary Artery Disease—The THORESCI Study
Conclusions: The ESC screener contributes to the search for a multidimensional and easy-to-use psychosocial screening instrument for cardiac patients. Although the screener, in its current form, may not be sufficiently valid to reliably detect all predefined psychosocial factors, screening scores for depression and anxiety might be useful in clinical practice. Our findings can be used for further refinement and validation of the screener. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Positive and Negative Affect Is Related to Experiencing Chest Pain During Exercise-Induced Myocardial Ischemia
Conclusions: Patients who experience higher NA are more likely to report experiencing chest pain. In patients without ischemia, high NA and PA was also associated with a higher likelihood of reporting chest pain. Results suggest that high levels of PA as well as NA may increase the experience and/or reporting of chest pain. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Placebo Analgesic Effect in Healthy Individuals and Patients: A Meta-Analysis
Conclusions: The findings suggest that patients benefited from placebo treatment to a greater degree than healthy individuals did and that studies on healthy individuals may underestimate the magnitude of the placebo analgesic effect in patients. Patients' clinical pain and experimentally induced pain respond to placebo to the same degree. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Systematic Review/Meta-Analysis Source Type: research

Self-Transcendent Values and Neural Responses to Threatening Health Messages
Conclusions: Attenuated neural reactivity to potentially threatening health messages may be a novel way that prioritizing self-transcendent values could lead to positive health behaviors. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Original Article Source Type: research

The Neurobiology of Health Communication
ABSTRACT: This issue of Psychosomatic Medicine describes findings from an innovative study by Kang et al that used neuroimaging methods to quantify neural responses to health communications. Findings indicated that sedentary individuals who hold self-transcendent values show attenuated limbic threat responses to communications about the benefits of physical activity. Furthermore, participants who were instructed to articulate such values showed some evidence of additional blunting of the same neural response. In this editorial, we provide context for the interpretation of these findings within the existing research using t...
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Comment Source Type: research

Article Summaries for May 2017 Psychosomatic Medicine, Volume 79, Issue 4
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - May 1, 2017 Category: Psychiatry & Psychology Tags: In This Issue Source Type: research

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Source: Psychosomatic Medicine - April 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2017 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research