Stress and Addiction: When a Robust Stress Response Indicates Resiliency
ConclusionsA blunted stress response may indicate long-term physiological dysregulation that could usher harmful consequences for cardiovascular disease, pain perception, and addictive disorders. The impact of dysregulation is influenced by multiple individual and situational factors that should be considered in evaluating the clinical significance of stress response dysregulation. Objective Stress reactivity research has traditionally focused on the idea that exaggerated responses to stress may have adverse effects on health. Accumulating evidence suggests that attenuated responses to stress and delayed recovery may a...
Source: Psychosomatic Medicine - January 1, 2018 Category: Psychiatry & Psychology Tags: Review Source Type: research

Article Summaries for January 2018 Psychosomatic Medicine, Volume 80, Issue 1
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 1, 2018 Category: Psychiatry & Psychology Tags: In This Issue Source Type: research

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Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

Psychosomatic Medicine Reviewers in 2017
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Reviewers in 2017 Source Type: research

Everyday Discrimination and Metabolic Syndrome Incidence in a Racially/Ethnically Diverse Sample: Study of Women's Health Across the Nation
ABSTRACTObjectiveEveryday discrimination may contribute to incident metabolic syndrome (MetS) in the United States and related racial/ethnic differences in MetS. The study investigated whether everyday discrimination predicted MetS in a diverse sample.MethodsA longitudinal, cohort study of 2132 women (mean [standard deviation] = 45.8 [2.7] years) who self-reported as black (n = 523), white (n = 1065), Chinese (n = 194), Japanese (n = 227), or Hispanic (n = 123) at baseline drawn from seven cities across the United States was conducted. MetS was defined in accordance with the National Cholesterol Education Program Adult Tre...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

A Systematic Review and Meta-analysis of the Effort-Reward Imbalance Model of Workplace Stress and Hypothalamic-Pituitary-Adrenal Axis Measures of Stress
ABSTRACTObjectiveThe association between effort-reward imbalance (ERI) and various health outcomes has been well documented over the past 20 years, but the mechanisms responsible for this association remain unclear. The present meta-analysis assessed the associations of ERI and overcommitment (OC) in the workplace with hypothalamic-pituitary-adrenal (HPA) axis measures.MethodsElectronic databases were searched with the phrase “effort*reward*imbalance,” which yielded 319 studies leading to 56 full-text studies being screened. Thirty-two studies within 14 articles met inclusion criteria and were meta-analyzed usi...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Systematic Review/Meta-Analysis Source Type: research

Prognostic Value of Type D Personality for In-stent Restenosis in Coronary Artery Disease Patients Treated With Drug-Eluting Stent
ConclusionsIn this study, Type D personality was an independent predictor of ISR at 1 and 2 years post-PCI; the association strengthened with time. The negative affectivity component seems to drive the relationship between Type D and ISR over time. Our findings provide new insights into the mechanisms involved in the association between Type D and adverse clinical outcomes of PCI. Objective To evaluate the predictive value of Type D personality on in-stent restenosis (ISR) rates at 1 and 2 years post–percutaneous coronary intervention (PCI) in patients with coronary artery disease. Methods Consecutive patients...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Proinflammatory Cytokines, Mood, and Sleep in Interepisode Bipolar Disorder and Insomnia: A Pilot Study With Implications for Psychosocial Interventions
ConclusionsThese findings provide preliminary evidence that IL-6 is related to mania symptoms and shorter total sleep time in interepisode BD. A treatment that targets sleep in BD could potentially decrease IL-6 although replication is warranted. Objective Proinflammatory cytokines are associated with bipolar disorder (BD), but less is known about how cytokines function during the interepisode period. This study examined cytokines, mood symptoms, and sleep in individuals with interepisode BD with complaints of insomnia. We also investigated the effects of a BD-specific modification of cognitive behavior therapy for ins...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Sleep Duration and Quality as Related to Left Ventricular Structure and Function
ABSTRACTObjectiveInadequate sleep is associated with increased risk of cardiovascular events; however, the associations between sleep duration or quality and cardiac function or structure are not well understood. This cross-sectional study was conducted to investigate to what extent sleep duration and quality are associated with left ventricular (LV) diastolic dysfunction or structural deterioration.MethodsA total of 31,598 healthy Korean adults who received echocardiography and completed the Pittsburg Sleep Quality Index were enrolled in this study. Participants were stratified into three groups by self-reported sleep dur...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Role of Brain Structure in Predicting Adherence to a Physical Activity Regimen
In this study, we tested whether gray matter volume and white matter microstructural integrity before the initiation of a PA intervention predicts PA adherence.MethodsOne hundred fifty-nine adults aged 60 to 80 years were randomly assigned to a moderate-intensity aerobic walking condition or a nonaerobic stretching and toning condition. Participants engaged in supervised exercise 3 times per week for 12 months. Data were collected for a period of 1 year. Voxel-based morphometry and tract-based spatial statistics protocols were used to process neuroimaging data, and ordinary least squares regression models with bootstrappin...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Partner Loss in Monogamous Rodents: Modulation of Pain and Emotional Behavior in Male Prairie Voles
ABSTRACTObjectivePain is modulated by psychosocial factors, and social stress–induced hyperalgesia is a common clinical symptom in pain disorders. To provide a new animal model for studying social modulation of pain, we examined pain behaviors in monogamous prairie voles experiencing partner loss.MethodsAfter cohabitation with novel females, males (n = 79) were divided into two groups on the basis of preference test scores. Half of the males of each group were separated from their partner (loss group), whereas the other half remained paired (paired group). Thus, males from both groups experienced social isolation. Op...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Association of Posttraumatic Stress Disorder With Clinic and Ambulatory Blood Pressure in Healthy Adults
ABSTRACTObjectivePosttraumatic stress disorder (PTSD) is associated with incident cardiovascular risk. We tested the association of PTSD with clinic and ambulatory blood pressure (ABP) in a sample of healthy participants and tested ABP reactivity to anxiety as a mechanism by which PTSD may influence blood pressure (BP).MethodsParticipants were originally enrolled during workplace BP screenings at three sites; approximately 6 years (standard deviation = 1.0) later, they completed nine clinic BP assessments within three visits, 1 week apart. Before the third visit, participants were screened for PTSD (≥33 on the PTSD Chec...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

An Evaluation of Perceived Health Risk and Depressive Symptoms Before a Disaster in Predicting Postdisaster Inflammation
ConclusionsThese findings add to our understanding of the complex interactions between stress, depression, and immune responses. Indeed, findings provide a potential mechanism (i.e., inflammation) explaining the association between exposure to major life stressors and negative mental and physical health outcomes. Objective Exposure to major life stressors is associated with subsequent enhanced inflammation-related disease processes. Depressive symptoms exacerbate stress-induced inflammatory responses. Moreover, those who report a high degree of perceived health risk before being exposed to a major life stressor such as...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Accelerated DNA Methylation Age: Associations With Posttraumatic Stress Disorder and Mortality
ConclusionsFindings of this study replicate the association between PTSD and accelerated DNAm age and suggest that this effect may be specific to the hyperarousal symptom cluster. Results point to the potential utility of DNAm age algorithms for identifying individuals who are aging at an accelerated rate and for determining the factors that influence this process. Objective Recently developed indices of cellular age based on DNA methylation (DNAm) data, referred to as DNAm age, are being used to study factors that influence the rate of aging and the health correlates of these metrics of the epigenetic clock. This stud...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Prenatal Stress, Methylation in Inflammation-Related Genes, and Adiposity Measures in Early Childhood: the Programming Research in Obesity, Growth Environment and Social Stress Cohort Study
ConclusionsPrenatal stress was associated with decreased childhood adiposity, whereas cord blood IL6 methylation was associated with increased childhood adiposity in Mexican children. Objective Maternal stress during pregnancy may influence childhood growth and adiposity, possibly through immune/inflammatory programming. We investigated whether exposure to prenatal stress and methylation in inflammation-related genes were associated with childhood adiposity in 424 mother-child pairs in Mexico City, Mexico. Methods A stress index was created based on four prenatally administered stress-related scales (Exposure to Vio...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Perceived Stress, Depressive Symptoms, and Oxidative DNA Damage
ConclusionsIn a general Japanese population, we found a weak positive association between perceived stress and urinary excretion of 8-OHdG, whereas no association was observed between depressive symptoms and 8-OHdG. Further studies are needed to examine whether the association between perceived stress and 8-OHdG is modified by depressive symptoms. Objective Psychosocial stress may influence the risk of disease through its association with oxidative DNA damage. We examined whether perceived stress and depressive symptoms were associated with urinary excretion of 8-hydroxydeoxyguanosine (8-OHdG), with mutual interaction ...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Assessing Lifetime Stress Exposure Using the Stress and Adversity Inventory for Adults (Adult STRAIN): An Overview and Initial Validation
ConclusionsThe STRAIN demonstrated good usability and acceptability; very good concurrent, discriminant, and predictive validity; and excellent test-retest reliability. Objective Numerous theories have proposed that acute and chronic stressors may exert a cumulative effect on life-span health by causing biological “wear and tear,” or allostatic load, which in turn promotes disease. Very few studies have directly tested such models, though, partly because of the challenges associated with efficiently assessing stress exposure over the entire life course. To address this issue, we developed the first online s...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Stress and Addiction: When a Robust Stress Response Indicates Resiliency
ConclusionsA blunted stress response may indicate long-term physiological dysregulation that could usher harmful consequences for cardiovascular disease, pain perception, and addictive disorders. The impact of dysregulation is influenced by multiple individual and situational factors that should be considered in evaluating the clinical significance of stress response dysregulation. Objective Stress reactivity research has traditionally focused on the idea that exaggerated responses to stress may have adverse effects on health. Accumulating evidence suggests that attenuated responses to stress and delayed recovery may a...
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: Review Source Type: research

Article Summaries for January 2018 Psychosomatic Medicine, Volume 80, Issue 1
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 27, 2017 Category: Psychiatry & Psychology Tags: In This Issue Source Type: research

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Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

Research on Somatization and Somatic Symptom Disorders: Ars longa, vita brevis
ABSTRACT The new Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition defines somatic symptom and related disorders as long-standing somatic symptoms that are associated with disproportionate thoughts, feelings, and behaviors, irrespective of whether or not a medical cause for these symptoms can be determined. In this Special Section of Psychosomatic Medicine, several articles address diagnostic issues and the central nervous system correlates of somatic symptom and related disorder and document new developments in its treatment. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Comment Source Type: research

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Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover.
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Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

Author and Subject Index
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Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Volume Contents and Index Source Type: research

Volume contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Volume Contents and Index Source Type: research

The Association of Work Characteristics With Ovarian Cancer Risk and Mortality
Conclusions: We did not observe clear associations between work characteristics and OvCA incidence or mortality, but further research with diverse populations is warranted. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Identification and Validation of Clinically Relevant Clusters of Severe Fatigue in Rheumatoid Arthritis
Conclusions: Among RA patients with severe fatigue, recruited to two diverse RA cohorts, clinically relevant clusters were identified and validated. These may provide the basis for future mechanistic studies and ultimately support a stratified approach to fatigue management. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Association of Cigarette Smoking With High-Frequency Heart Rate Variability: An Ecological Momentary Assessment Study
Conclusions: In healthy smokers with high hostility levels used as their own controls during daily living, smoking acutely reduced HF-HRV. HF-HRV was also reduced in smokers as compared with nonsmokers. Although limited by a small sample of individuals with high hostility levels, these findings nonetheless provide additional evidence that cardiac vagal regulation is lowered by cigarette smoking, which may be one of the numerous pathophysiological effects of smoking. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Role of Psychological Stress on Heart Autophagy in Mice With Heart Failure
Conclusions: Psychological stress may contribute to the development of CHF by enhancing heart oxidative stress and impairing autophagy flux. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

The Clinical Significance of Posterior Insular Volume in Adolescent Anorexia Nervosa
Objective: The diagnostic criterion disturbance in the experience of the body remains a poorly understood and persistent feature of anorexia nervosa (AN). Increased sophistication in understanding the structure of the insular cortex—a neural structure that receives and integrates visceral sensations with action and meaning—may elucidate the nature of this disturbance. We explored age, weight status, illness severity, and self-reported body dissatisfaction associations with insular cortex volume. Methods: Structural magnetic resonance imaging data were collected from 21 adolescents with a history of AN and 20 a...
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Effectiveness of a Stepped, Collaborative, and Coordinated Health Care Network for Somatoform Disorders (Sofu-Net): A Controlled Cluster Cohort Study
Conclusions: The treatment of somatoform disorders within a guideline-based health care network resulted in increased rates of mental health treatment but failed to improve patient clinical outcomes. Future investigations are needed to investigate the combined value of health care networks with specialized psychotherapy interventions in patients at high risk of somatic symptom and related disorders. Trial Registration: ISRCTN55870770. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Core Outcome Domains for Clinical Trials on Somatic Symptom Disorder, Bodily Distress Disorder, and Functional Somatic Syndromes: European Network on Somatic Symptom Disorders Recommendations
Conclusions: The proposed criteria are intended to improve synergies of clinical trials and to facilitate decision making when comparing different treatment approaches. These recommendations should not result in inflexible guidelines, but increase consistency across investigations in this field. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Inducing Somatic Symptoms in Functional Syndrome Patients: Effects of Manipulating State Negative Affect
Objective: Induction of negative affective states can enhance bodily symptoms in high habitual symptom reporters among healthy persons and in patients with irritable bowel syndrome. The aims of this study were to replicate this effect in patients with fibromyalgia and chronic fatigue syndrome and to investigate the role of moderators, focusing on alexithymia, negative affectivity, and absorption. Methods: Patients with fibromyalgia and/or chronic fatigue syndrome (n = 81) and HCs (n = 41) viewed series of neutral, positive, and negative affective pictures. After every picture series, participants filled out a somatic symp...
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Influence of Uncertain Anticipation on Brain Responses to Aversive Rectal Distension in Patients With Irritable Bowel Syndrome
Conclusions: Preceding uncertainty differentially modulates the brain processing of physiologically identical rectal stimulation in IBS patients. Cue-dependent alterations in brain responses may underlie hypervigilance to visceral sensations in IBS patients. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Features of Resting-State Electroencephalogram Theta Coherence in Somatic Symptom Disorder Compared With Major Depressive Disorder: A Pilot Study
Conclusions: Both SSD and MDD patients commonly showed decreased functional connectivity within the left temporoparietal junction, which has neurophysiological implications for cognitive-attentional processing and social interaction. Frontostriatal circuit dysfunction affects processes that control perception and emotion, as well as misperception of somatosensory data in the parietal somatosensory area, and is more likely to be a neuropathology of SSD than MDD. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Screening for DSM-5 Somatic Symptom Disorder: Diagnostic Accuracy of Self-Report Measures Within a Population Sample
This study investigates the diagnostic accuracy of three self-report questionnaires that measure somatic complaints (15 item Patient Health Questionnaire [PHQ-15]) and psychological features (7-item Whiteley Index [WI-7]; Scale for Assessing Illness Behavior [SAIB]), in detecting somatic symptom disorder. Methods: A nationally representative general population survey was performed resulting in 250 participants (minimum age = 14 years. 12.8% participation rate). Assessment took place at baseline and 12-month follow-up. Individual and combined diagnostic accuracy of the PHQ-15, WI-7, and SAIB in detecting somatic symptom di...
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Original Articles Source Type: research

Research on Somatization and Somatic Symptom Disorders: Ars longa, vita brevis
ABSTRACT: The new Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition defines somatic symptom and related disorders as long-standing somatic symptoms that are associated with disproportionate thoughts, feelings, and behaviors, irrespective of whether or not a medical cause for these symptoms can be determined. In this Special Section of Psychosomatic Medicine, several articles address diagnostic issues and the central nervous system correlates of somatic symptom and related disorder and document new developments in its treatment. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Comment Source Type: research

Past, Present, and Future of Psychosomatic Movements in an Ever-Changing World: Presidential Address
Conclusions: Psychosomatic medicine has its roots in the beginnings of medicine. During the past 75 years, it has made substantial contributions to the science and practice of medicine. The field has also changed in response to developments in medicine, technology, and society and is facing new challenges and opportunities that may require further adaptation of its concepts and practice. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: Review Source Type: research

Article Summaries for November–December 2017 Psychosomatic Medicine, Volume 79, Issue 9
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2017 Category: Psychiatry & Psychology Tags: In This Issue Source Type: research

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Source: Psychosomatic Medicine - October 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2017 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

All Issue Ads.
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2017 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2017 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2017 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research