How to Deal With Temporal Relationships Between Biopsychosocial Variables: A Practical Guide to Time Series Analysis
Conclusions Time series designs enable modeling of temporal relationships and bidirectional associations between biopsychosocial variables within individuals. These individual patterns cannot be derived from traditional group-based statistical analyses. This article provides accessible research tools for conducting TSA relevant to psychosomatic and biobehavioral research. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: METHODS AND STATISTICS Source Type: research

Associations Between Cannabis Use and Cardiometabolic Risk Factors: A Longitudinal Study of Men
This study tested longitudinal associations between cannabis use and cardiometabolic risk factors that underlie the development of cardiovascular diseases. Methods Participants were men from the youngest cohort of the Pittsburgh Youth Study who were followed prospectively from approximately age 7 to 32 years (N = 253). Frequency of cannabis use was assessed yearly from approximately ages 12 to 20 years and again at approximately ages 26, 29, and 32 years. The following cardiometabolic risk factors were assessed during a laboratory visit at approximately age 32 years: body mass index (BMI), waist-hip ratio, high- and low...
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLE Source Type: research

The Effects of Dietary Improvement on Symptoms of Depression and Anxiety: A Meta-Analysis of Randomized Controlled Trials
Conclusions Dietary interventions hold promise as a novel intervention for reducing symptoms of depression across the population. Future research is required to determine the specific components of dietary interventions that improve mental health, explore underlying mechanisms, and establish effective schemes for delivering these interventions in clinical and public health settings. Registration PROSPERO Online Protocol: CRD42018091256. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: SYSTEMATIC REVIEW/META-ANALYSIS Source Type: research

Psychological Traits, Heart Rate Variability, and Risk of Coronary Heart Disease in Healthy Aging Women—The Women's Health Initiative
Conclusions HRV did not play a major role in explaining why more optimistic women seem to be somewhat protected from CHD risk. Although hostility was inversely associated with HRV, its role in explaining the association between hostility and CHD risk remains to be established. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLE Source Type: research

Major Depressive Disorder in Medical Illness: A Review of Assessment, Prevalence, and Treatment Options
Major depression, as well as other depressive disorders, is commonly comorbid with other medical illnesses, particularly chronic and systemic medical illnesses. The co-occurrence of the disorders is so common that it challenges our notions of the meaning of comorbidity and our desire to neatly separate psychiatric and medical illnesses. The overlap between symptoms of physical illness and the neurovegetative symptoms of major depression and the initial normative emotional response to physical illness add to the challenge of accurate diagnosis and timely treatment of depression in the medically ill. We review the literature...
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: CLINICAL APPLICATIONS Source Type: research

Coronary Artery Spasm as Related to Anxiety and Depression: A Nationwide Population-Based Study
Objective Anxiety and depression are risk factors for obstructive coronary artery disease (CAD), but their effects on coronary artery spasm (CAS) remain unestablished. Methods Patient records in this population-based study were retrospectively collected from the Taiwan National Health Insurance Research Database. Using propensity score matching, we used 1:1:1 ratio stratification into a control group of 10,325 individuals without CAS or CAD, a CAS group comprising 10,473 patients, and a CAD group comprising 10,473 patients during 2000–2012. Results The prevalence of CAS and CAD was 0.067% and 8.7%, respective...
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLE Source Type: research

Coronary Artery Spasm, Coronary Reactivity, and Their Psychological Context
Symptomatic individuals suspected of having myocardial ischemia often have no obstructive atherosclerotic narrowing of epicardial coronary arteries. Abnormal coronary vascular reactivity and, in particular, coronary artery vasospasm (CAS) may be an explanation in a subset of these patients. Psychological factors play an important role in ischemic heart disease, but their role in CAS is not clear; autonomic dysfunction and increased inflammation are two prevailing pathophysiological mechanisms implicated in abnormal coronary reactivity resulting from mental health conditions. Interrelationships between psychological factors...
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: EDITORIAL COMMENT Source Type: research

Mindfulness Training and Physical Health: Mechanisms and Outcomes
Conclusions We conclude with new opportunities for research and clinical implementations to consider in the next two decades. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: REVIEW Source Type: research

Article Summaries for April 2019 Psychosomatic Medicine, Volume 81, Issue 3
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - April 1, 2019 Category: Psychiatry & Psychology Tags: IN THIS ISSUE Source Type: research

Facial Emotion Recognition Abilities in Women Experiencing Eating Disorders
Conclusions Overall, within-subject effects were as expected, whereas between-subject effects were marginal and psychopathology did not influence emotion recognition. Facial emotion recognition abilities in women experiencing EDs compared with women experiencing mixed mental disorders and healthy controls were similar. Although basic facial emotion recognition processes seems to be intact, dysfunctional aspects such as misinterpretation might be important in emotion regulation problems. Clinical Trial Registration Number: DRKS-ID: DRKS00005709. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - February 1, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome
Objective Imaging studies in adults with irritable bowel syndrome (IBS) have shown both morphological and resting state (RS) functional connectivity (FC) alterations related to cortical modulation of sensory processing. Because analogous differences have not been adequately investigated in children, this study compared gray matter volume (GMV) and RS-FC between girls with IBS and healthy controls (HC) and tested the correlation between brain metrics and laboratory-based pain thresholds (Pth). Methods Girls with Rome III criteria IBS (n = 32) and matched HCs (n = 26) were recruited. In a subset of patients, Pth were de...
Source: Psychosomatic Medicine - February 1, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

All Issue Ads
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

Psychosomatic Medicine Reviewers in 2018
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: REVIEWERS IN 2018 Source Type: research

Early-Life Home Environment and Obesity in a Mexican American Birth Cohort: The CHAMACOS Study
Conclusions This study adds new evidence that adverse and protective aspects of the home environment could lead to altered obesity status in children. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Diurnal Cortisol in a Sample of Socioeconomically Disadvantaged Chinese Children: Evidence for the Shift-and-Persist Hypothesis
This study explored whether the psychological strategy of “shift-and-persist” protects low-SES children from stress-related physiological risks, as measured through blunted (unhealthy) diurnal cortisol profiles. Methods A sample of 645 children (aged 8–15 years) from low-SES backgrounds and having at least one HIV-positive parent completed a battery of psychological scales. Diurnal cortisol assessments included collection of saliva samples four times a day for 3 days, from which three cortisol parameters (cortisol at awakening, cortisol awakening response, and cortisol slope) were derived. Results H...
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Coping, Mood, Quality of Life, and Outcomes in Recipients of Left Ventricular Assist Devices: A Cluster Analysis
Objective Left ventricular assist devices (LVADs) are increasingly used for temporary circulatory support until transplant or as destination therapy for patients with end-stage heart failure. Understanding patients' attitudes and resources is crucial to support them. Methods Sixty-one LVAD recipients (55 [10] years, 10% women, 15% destination therapy) participating in cardiac rehabilitation (CR) postimplant underwent assessment of coping styles (Coping Orientation for Problem Experiences), quality of life (Medical Outcomes Study Short-Form 36, Minnesota Living with Heart Failure Questionnaire), and mood (Hospital Anxi...
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Association Between Endothelial Function and Cognitive Performance in Patients With Coronary Artery Disease During Cardiac Rehabilitation
Conclusions RHI may be a clinically useful predictor of cognitive change and might provide insight into the etiology of cognitive dysfunction in patients with CAD. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Depressive Symptoms During Childhood and Cardiovascular Risk Factors in Black and White Men
Conclusions Depressive symptoms in childhood may predict later adverse health behaviors in black and white men. No evidence was found for an association between childhood depressive symptoms with metabolic syndrome or inflammation markers at ages approximately 32 years. The nature of the sample and lack of measurement of depressive disorder diagnosis tempers the conclusions, and future research is needed to determine associations with biological measures at later life span phases. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

A Pilot Randomized Trial Assessing the Effect of a Psychoeducational Intervention on Psychoneuroimmunological Parameters Among Patients With Nonmetastatic Breast Cancer
Objective The aim of this study was to determine a potential benefit of the specific psychoeducational intervention “Learning to Live with Cancer” (LTLWC) for patients with operated nonmetastatic breast cancer, with respect to psychological variables and endocrine and immune parameters. Methods Fifty-two postmenopausal women with operated stage I to III breast cancer were randomized to either a breast cancer intervention group (BCIG, n = 30) who immediately began participating in the LTLWC intervention program or to a breast cancer control group (BCCG, n = 22). Matched healthy women were asked to participa...
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Facial Emotion Recognition Abilities in Women Experiencing Eating Disorders
Conclusions Overall, within-subject effects were as expected, whereas between-subject effects were marginal and psychopathology did not influence emotion recognition. Facial emotion recognition abilities in women experiencing EDs compared with women experiencing mixed mental disorders and healthy controls were similar. Although basic facial emotion recognition processes seems to be intact, dysfunctional aspects such as misinterpretation might be important in emotion regulation problems. Clinical Trial Registration Number: DRKS-ID: DRKS00005709. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome
Objective Imaging studies in adults with irritable bowel syndrome (IBS) have shown both morphological and resting state (RS) functional connectivity (FC) alterations related to cortical modulation of sensory processing. Because analogous differences have not been adequately investigated in children, this study compared gray matter volume (GMV) and RS-FC between girls with IBS and healthy controls (HC) and tested the correlation between brain metrics and laboratory-based pain thresholds (Pth). Methods Girls with Rome III criteria IBS (n = 32) and matched HCs (n = 26) were recruited. In a subset of patients, Pth were de...
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

An Embodied Neurocomputational Framework for Organically Integrating Biopsychosocial Processes: An Application to the Role of Social Support in Health and Disease
Conclusions By highlighting these pathways, the resulting model has important implications motivating a more psychologically sophisticated, person-specific approach to future research and clinical application in the biopsychosocial domain. It also highlights the potential for quantitative computational modeling and the design of novel interventions. Finally, it should aid in guiding future research in a manner capable of addressing the current criticisms/limitations of the biopsychosocial model and may therefore represent an important step in bridging the gap between it and the biomedical perspective. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: REVIEW Source Type: research

Psychological Therapy for Centralized Pain: An Integrative Assessment and Treatment Model
Conclusions This integrative assessment and treatment model has the potential to substantially reduce and sometimes eliminate centralized pain by changing the cognitive, behavioral, emotional, and interpersonal processes that trigger and maintain centralized pain. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: CLINICAL APPLICATIONS Source Type: research

Introducing a New Special Series: Clinical Applications in Psychosomatic Medicine
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: EDITORIAL COMMENT Source Type: research

Article Summaries for February–March 2019 Psychosomatic Medicine, Volume 81, Issue 2
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - January 31, 2019 Category: Psychiatry & Psychology Tags: IN THIS ISSUE Source Type: research

All Issue Ads
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research

The Effect of Traditional Chinese Medicine Zhike-Houpu Herbal Pair on Depressive Behaviors and Hippocampal Serotonin 1A Receptors in Rats After Chronic Unpredictable Mild Stress
Conclusions These data show that ZKHPHP has antidepressant-like effects based on a chronic unpredictable mild stress-induced depression model in rats. ZKHPHP may be attractive as an antidepressant because of its beneficial effects on depression and the absence of gastrointestinal dysregulation, which is a frequently observed unintended effect of many commonly used antidepressive medications. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Computerized Exposure Therapy for Spider Phobia: Effects of Cardiac Timing and Interoceptive Ability on Subjective and Behavioral Outcomes
Conclusions Interoceptive information influences exposure benefit. The reduction in the subjective expression of fear/phobia is facilitated by “bottom-up” afferent signals, whereas improvement in the behavioral expression is further dependent on “top-down” representation of self-related physiology (heart rhythm). Individual interoceptive differences moderate these effects, suggesting means to personalize therapy. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Daily Stress Processes as Contributors to and Targets for Promoting Cognitive Health in Later Life
Conclusions Negative affect reactions to daily stressors are associated with compromised RTI both between and within-persons. Findings suggest that emotional reactions to daily stressors contribute to compromise older adults' cognitive health, whereas increased positive affect may be beneficial. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Longitudinal Associations Between Inflammation and Depressive Symptoms in Chronic Dialysis Patients
Conclusions We confirmed the presence of cross-sectional associations between inflammation markers and depressive symptoms in chronic dialysis patients, but with our longitudinal data, we found no longitudinal associations. This supports an associative instead of a causal relationship between inflammation and depressive symptoms. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Bereavement, Self-Reported Sleep Disturbances, and Inflammation: Results From Project HEART
Conclusions These findings provide preliminary evidence that bereavement moderates the association between self-reported sleep disturbances and inflammation. Future studies should examine the course of sleep disturbances after bereavement and establish whether objective sleep has differential associations with inflammation among bereaved adults. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Sex-Specific Association Between Coronary Artery Disease Severity and Myocardial Ischemia Induced by Mental Stress
Conclusions Findings suggest that CAD severity is related to MSIMI in men but not women. MSIMI in women may therefore be driven by alternative mechanisms such as coronary microvascular disease. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

The Relationship Between Daytime Salivary Melatonin and Gastrointestinal Symptoms in Young Adults Seeking Psychiatric Care
Conclusions In young adult psychiatric patients, salivary melatonin levels after lunch are associated with gastrointestinal symptoms, which is consistent with the proposed effect of elevated levels of gastrointestinal melatonin on gut motility. This result suggests a link between IBS symptoms and regulation of melatonin in patients with psychiatric disorders. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Altered Hypothalamus-Pituitary-Adrenal Axis Function: A Potential Underlying Biological Pathway for Multiple Concurrent Symptoms in Patients With Advanced Lung Cancer
Objective Patients with advanced cancer commonly experience multiple symptoms that present as groups or clusters. The present study aimed to examine whether hypothalamus-pituitary-adrenal (HPA) axis dysfunction underlies the concurrent multiple symptoms in patients with advanced cancer. Methods Patients' cortisol levels were determined in saliva samples collected after awakening (0, 30, and 60 minutes after awakening) and at nighttime (21:00–22:00 PM) from 46 patients with lung cancer (15.2% women), with a mean (standard deviation) age of 64.3 (9.2) years and 47 healthy participants (53.2% women; age = 62.0 [4.6...
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

The Effects of Tryptophan Enhancement and Depletion on Plasma Catecholamine Levels in Healthy Individuals
In this study, we examine the effects of tryptophan enhancement and depletion on plasma catecholamine levels in humans. Methods The total sample consisted of 164 healthy men and women who were tested for 2 days. Seventy-nine participants were randomized to a tryptophan enhancement condition and 85 to a tryptophan depletion condition. Both protocols consisted of a “sham day,” followed by an “active day.” Blood samples for assessment of plasma norepinephrine and epinephrine levels were collected before and after tryptophan enhancement/depletion. Data were analyzed using general linear models. Separ...
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Mismatch in Spouses' Anger-Coping Response Styles and Risk of Early Mortality: A 32-Year Follow-Up Study
Objective Research in psychosomatic medicine includes a long history of studying how responses to anger-provoking situations are associated with health. In the context of a marriage, spouses may differ in their anger-coping response style. Where one person may express anger in response to unfair, aggressive interpersonal interactions, his/her partner may instead suppress anger. Discordant response styles within couples may lead to increased relational conflict, which, in turn, may undermine long-term health. The current study sought to examine the association between spouses' anger-coping response styles and mortality st...
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Intimacy as Related to Cortisol Reactivity and Recovery in Couples Undergoing Psychosocial Stress
Conclusions Spontaneous nonverbal expressions of intimacy seem to regulate the effects of acute environmental demands on established biological indices of stress response. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Perceived Partner Responsiveness, Daily Negative Affect Reactivity, and All-Cause Mortality: A 20-Year Longitudinal Study
Conclusions These findings are among the first to provide direct evidence of psychological mechanisms underlying the links between intimate relationships and mortality and have implications for research aiming to develop interventions that increase or maintain responsiveness in relationships over time. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Relationships Matter: Progress and Challenges in Research on the Health Effects of Intimate Relationships
Social connections play an important role in health and disease and provide opportunities for clinical and public health interventions. Marriage and similar intimate relationships play a central role in the potential health benefits of positive social connections. This editorial provides an integrative perspective on three papers in this issue of Psychosomatic Medicine that examine intimate relationships and health and illustrates the application of current areas in relationship science. The importance of integrated conceptual models and statistical techniques to disentangle common third factors and overlapping constructs ...
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: EDITORIAL COMMENT Source Type: research

Article Summaries for January 2019 Psychosomatic Medicine, Volume 81, Issue 1
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - December 23, 2018 Category: Psychiatry & Psychology Tags: IN THIS ISSUE Source Type: research

All Issue Ads
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2018 Category: Psychiatry & Psychology Tags: All Issue Ads: PDF Only Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2018 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2018 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2018 Category: Psychiatry & Psychology Tags: Cover: PDF Only Source Type: research