Longitudinal Relationship Between Posttraumatic Stress Symptoms and Physical Symptoms in Military Veterans
This study aimed to assess the temporal relationship of posttraumatic stress disorder (PTSD) symptoms and physical symptoms in a non–treatment-seeking deployed military sample. Methods Data were from a longitudinal study of Australian Defence Force personnel deployed to the Middle East Area of Operations between 2010 and 2012 (n = 1871). Predeployment assessment was conducted 4 months before deployment (T1). Of these, 1324 (70.8% retention rate) participated in assessment within 4 months after deployment (T2), and 1122 (60.0%) completed the third time point at 4 years after deployment (T3). PTSD symptoms were asse...
Source: Psychosomatic Medicine - November 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Relationship Between Abuse History and Gastrointestinal and Extraintestinal Symptom Severity in Irritable Bowel Syndrome
This study aimed to investigate the associations between the different abuse types, and gastrointestinal (GI) and extraintestinal symptom severity in irritable bowel syndrome (IBS), and possible mediators of these relationships. Methods We assessed sexual and physical abuse in childhood and adulthood with the Drossman and Leserman abuse questionnaire, whereas GI and extraintestinal symptoms were assessed with the Gastrointestinal Symptom Rating Scale and the Symptom Check List-90 Revised. General linear models with bootstrapping tested the mediating role of depressive symptoms, anxiety symptoms, and GI-specific anxi...
Source: Psychosomatic Medicine - November 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Child Maltreatment and Inflammatory Response to Mental Stress Among Adults Who Have Survived a Myocardial Infarction
Conclusions These findings suggest sex differences in stress response among survivors of a myocardial infarction exposed to abuse early in life. They also underscore the importance of examining sex as an effect modifier of relationships between exposure to early life adversity and inflammatory responses to mental stressors in midlife. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Sleep Variability and Inflammation in Midlife and Older Women
Conclusions This study is the first to show that within-person changes in variable sleep duration are related to changes in inflammation. Findings from the current study suggest that greater variability in sleep duration is related to higher CRP, which may increase risk for early morbidity and mortality. Future studies should investigate inflammation as a pathway linking sleep variability and health. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Remotely Provided Open-Label Placebo Reduces Frequency of and Impairment by Allergic Symptoms
Conclusions Although OLP was able to lower the frequency of allergic symptoms and allergy-related impairment substantially, its effects on symptom severity were weaker. The remote provision of OLP suggests that physical contact between patients and providers might not be necessary for OLP to work. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Article Summaries for November–December 2022 Psychosomatic Medicine, Volume 84, Issue 9
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - November 1, 2022 Category: Psychiatry & Psychology Tags: IN THIS ISSUE Source Type: research

All Issue Ads
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: All Issue Ads Source Type: research

Table of Contents
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: Table of Contents Source Type: research

Editorial Board
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: Editorial Board Source Type: research

Cover
No abstract available (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: Cover Source Type: research

Through the Looking-Glass: Psychoneuroimmunology and the Microbiome-Gut-Brain Axis in the Modern Antiretroviral Therapy Era
Conclusions Advancing our understanding of PNI and microbiome-gut-brain axis pathways relevant to depression, substance use disorders, and other neuropsychiatric comorbidities in PWH can guide the development of novel biobehavioral interventions to optimize health outcomes. Recommendations are provided for biobehavioral and neurobehavioral research investigating bidirectional PNI and microbiome-gut-brain axis pathways among PWH in the modern antiretroviral therapy era. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: REVIEW Source Type: research

Individual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection
Conclusions Early HIV disease dynamics predict unfavorable CD4/CD8 T-cell ratio outcomes after ART. CD4+ and CD8+ T-cell trajectories contribute to inversion risk and correspond to specific viral, immune, and psychological profiles during AHI. Adjunctive strategies to achieve immune normalization merit consideration. (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Effect of Single Housing on Innate Immune Activation in Immunodeficiency Virus–Infected Pigtail Macaques (Macaca nemestrina) as a Model of Psychosocial Stress in Acute HIV Infection
This study assessed the impact of single housing, as a model of psychosocial stress, on innate immune responses of pigtailed macaques (Macaca nemestrina) during acute SIV infection. Methods A retrospective analysis of acute SIV infection of 2- to si6-year-old male pigtailed macaques was performed to compare the innate immune responses of socially (n = 41) and singly (n = 35) housed animals. Measures included absolute monocyte count and subsets, and in a subset (n ≤ 18) platelet counts and activation data. Results SIV infection resulted in the expected innate immune parameter changes with a modulating effect...
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Pain Is Associated With Depressive Symptoms, Inflammation, and Poorer Physical Function in Older Adults With HIV
We examined data from PLWH aged 54 to 78 years (n = 162) recruited from a single outpatient program for a larger study on HIV and aging. Participants reported depressive symptoms (10-item Center for Epidemiological Studies Depression Scale) and then attended a biomedical visit in which they reported past-month pain (Medical Outcomes Study-HIV pain subscale), completed physical function assessments, and provided blood samples (assayed for interleukin 6, interferon-γ, tumor necrosis factor α, and C-reactive protein). Links between pain, depressive symptoms, inflammation, and physical function were tested using linear regre...
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research

Sexual Minority Stress and Cellular Aging in Methamphetamine-Using Sexual Minority Men With Treated HIV
Objective Sexual minority men (e.g., gay, bisexual, and other men who have sex with men) experience stigma and sexual minority stress, which are theorized to drive negative health outcomes. Sexual minority men with treated HIV display persistent immune dysregulation, which could be amplified by sexual minority stress responses to potentiate cellular aging. Methods This cross-sectional study included 52 sexual minority men living with HIV who had undetectable viral load ( (Source: Psychosomatic Medicine)
Source: Psychosomatic Medicine - October 1, 2022 Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research