Relationship of < em > CYP3A4*1B < /em > Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis
CONCLUSION: The study demonstrated that the 392A > G polymorphism of the CYP3A4*1B gene (rs2740574) in patients with acute alcoholic hallucinosis does not affect the efficacy and safety rates of haloperidol therapy.PMID:38076668 | PMC:PMC10698852 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: A A Parkhomenko M S Zastrozhin VYu Skryabin A E Petukhov S A Pozdniakov V A Ivanchenko I A Zaytsev I V Bure P O Bochkov K A Akmalova V V Smirnov E A Bryun D A Sychev Source Type: research

Association of Psychopharmacological Medication Preference with Autistic Traits and Emotion Regulation in ADHD
CONCLUSIONS: This study highlights emotion regulation difficulties and how different emotional profiles may influence medication selection in children with ADHD.PMID:38076669 | PMC:PMC10698854 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Burcu Ozbaran Ipek Inal-Kaleli Nurhak Dogan Halil Ibrahim Colak Anil Altunkaya Beyza Ozbaran Sezen Kose Source Type: research

Relationship of the < em > 1846G < /em > & gt; < em > A < /em > Polymorphism of the < em > CYP2D6 < /em > Gene to the Equilibrium Concentration Levels of Haloperidol in Patients with Acute Alcoholic Hallucinosis
CONCLUSION: It can be concluded that patients with the GA genotype have a higher risk of ADRs compared to patients carrying the GG genotype. It is shown that 1846G > A polymorphism of the CYP2D6 gene (rs3892097) has a statistically significant effect on the equilibrium concentration levels of haloperidol.PMID:38076663 | PMC:PMC10698856 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: A A Parkhomenko M S Zastrozhin VYu Skryabin A E Petukhov S A Pozdniakov V A Ivanchenko I A Zaytsev I V Bure P O Bochkov K A Akmalova V V Smirnov E A Bryun D A Sychev Source Type: research

Treatment-Resistant Juvenile Depression-A Quicksand?
Psychopharmacol Bull. 2023 Dec 4;53(4):54-56.ABSTRACTThough research in juvenile depression is advancing, evidence examining effective treatments for Treatment-resistant juvenile depression remains at large limited. There is a dire need for more studies to help guide clinicians navigating these challenging cases.PMID:38076664 | PMC:PMC10698857 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Saxby Pridmore Hessa Alhazeem Bibi Alamiri Source Type: research

Rhabdomyolysis Complicated with Hyponatremia Due to Water Intoxication and Severe Aspiration Pneumonia: Description of a Patient with Chronic Schizophrenia and Literature Review
Psychopharmacol Bull. 2023 Dec 4;53(4):39-47.ABSTRACTHyponatremia due to water intoxication is frequently observed in patients with chronic schizophrenia. We herein present a 49-year-old man who developed schizophrenia at the age of 23 and had been admitted to the closed ward of our hospital for 7 years. He was found by a round nurse standing at the bedside, covering both ears with his hands and making groaning noises. He was disoriented and immediately after being returned to bed, a general tonic-clonic seizure occurred. Severe hyponatremia (Na 104 mEq/L) was noted and intravenous sodium correction was started. A few hour...
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Shintaro Watanabe Yoshio Sato Junya Miyaki Takefumi Suzuki Source Type: research

β-Blockers for Autism- < em > Help < /em > or < em > Hindrance < /em > ?
Psychopharmacol Bull. 2023 Dec 4;53(4):57-59.ABSTRACTA renewed interest in the use of β-blockers for neurodevelopmental disorders has recently resurfaced, notably as an addition to the limited psychopharmacological armamentarium of autism spectrum disorders (ASD). In this clinical perspective, authors decently argue this use could be advantageous and multi-folded for this population.PMID:38076666 | PMC:PMC10698851 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Seshni Gourika Moodliar-Rensburg Bibi Alamiri Source Type: research

Consequences of 1,4-Butanediol Misuse: A Review
Psychopharmacol Bull. 2023 Dec 4;53(4):48-53.ABSTRACTGamma-hydroxybutyrate (GHB), along with its precursors, 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL), are potent central depressant agents widely illicitly used for their euphoric and relaxant effects. The article presents a review of the literature on the 1,4-BD misuse, the clinical picture of intoxication, development of addiction and delirium. The available evidence shows that 1,4-BD is a substance with its own psychoactive effects, a high addiction potential and potentially severe withdrawal symptoms.PMID:38076667 | PMC:PMC10698855 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: VYu Skryabin YuB Shevtsova E A Novoselova Source Type: research

Relationship of < em > CYP3A4*1B < /em > Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis
CONCLUSION: The study demonstrated that the 392A > G polymorphism of the CYP3A4*1B gene (rs2740574) in patients with acute alcoholic hallucinosis does not affect the efficacy and safety rates of haloperidol therapy.PMID:38076668 | PMC:PMC10698852 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: A A Parkhomenko M S Zastrozhin VYu Skryabin A E Petukhov S A Pozdniakov V A Ivanchenko I A Zaytsev I V Bure P O Bochkov K A Akmalova V V Smirnov E A Bryun D A Sychev Source Type: research

Association of Psychopharmacological Medication Preference with Autistic Traits and Emotion Regulation in ADHD
CONCLUSIONS: This study highlights emotion regulation difficulties and how different emotional profiles may influence medication selection in children with ADHD.PMID:38076669 | PMC:PMC10698854 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Burcu Ozbaran Ipek Inal-Kaleli Nurhak Dogan Halil Ibrahim Colak Anil Altunkaya Beyza Ozbaran Sezen Kose Source Type: research

Relationship of the < em > 1846G < /em > & gt; < em > A < /em > Polymorphism of the < em > CYP2D6 < /em > Gene to the Equilibrium Concentration Levels of Haloperidol in Patients with Acute Alcoholic Hallucinosis
CONCLUSION: It can be concluded that patients with the GA genotype have a higher risk of ADRs compared to patients carrying the GG genotype. It is shown that 1846G > A polymorphism of the CYP2D6 gene (rs3892097) has a statistically significant effect on the equilibrium concentration levels of haloperidol.PMID:38076663 | PMC:PMC10698856 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: A A Parkhomenko M S Zastrozhin VYu Skryabin A E Petukhov S A Pozdniakov V A Ivanchenko I A Zaytsev I V Bure P O Bochkov K A Akmalova V V Smirnov E A Bryun D A Sychev Source Type: research

Treatment-Resistant Juvenile Depression-A Quicksand?
Psychopharmacol Bull. 2023 Dec 4;53(4):54-56.ABSTRACTThough research in juvenile depression is advancing, evidence examining effective treatments for Treatment-resistant juvenile depression remains at large limited. There is a dire need for more studies to help guide clinicians navigating these challenging cases.PMID:38076664 | PMC:PMC10698857 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Saxby Pridmore Hessa Alhazeem Bibi Alamiri Source Type: research

Rhabdomyolysis Complicated with Hyponatremia Due to Water Intoxication and Severe Aspiration Pneumonia: Description of a Patient with Chronic Schizophrenia and Literature Review
Psychopharmacol Bull. 2023 Dec 4;53(4):39-47.ABSTRACTHyponatremia due to water intoxication is frequently observed in patients with chronic schizophrenia. We herein present a 49-year-old man who developed schizophrenia at the age of 23 and had been admitted to the closed ward of our hospital for 7 years. He was found by a round nurse standing at the bedside, covering both ears with his hands and making groaning noises. He was disoriented and immediately after being returned to bed, a general tonic-clonic seizure occurred. Severe hyponatremia (Na 104 mEq/L) was noted and intravenous sodium correction was started. A few hour...
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Shintaro Watanabe Yoshio Sato Junya Miyaki Takefumi Suzuki Source Type: research

β-Blockers for Autism- < em > Help < /em > or < em > Hindrance < /em > ?
Psychopharmacol Bull. 2023 Dec 4;53(4):57-59.ABSTRACTA renewed interest in the use of β-blockers for neurodevelopmental disorders has recently resurfaced, notably as an addition to the limited psychopharmacological armamentarium of autism spectrum disorders (ASD). In this clinical perspective, authors decently argue this use could be advantageous and multi-folded for this population.PMID:38076666 | PMC:PMC10698851 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: Ahmed Naguy Seshni Gourika Moodliar-Rensburg Bibi Alamiri Source Type: research

Consequences of 1,4-Butanediol Misuse: A Review
Psychopharmacol Bull. 2023 Dec 4;53(4):48-53.ABSTRACTGamma-hydroxybutyrate (GHB), along with its precursors, 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL), are potent central depressant agents widely illicitly used for their euphoric and relaxant effects. The article presents a review of the literature on the 1,4-BD misuse, the clinical picture of intoxication, development of addiction and delirium. The available evidence shows that 1,4-BD is a substance with its own psychoactive effects, a high addiction potential and potentially severe withdrawal symptoms.PMID:38076667 | PMC:PMC10698855 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: VYu Skryabin YuB Shevtsova E A Novoselova Source Type: research

Relationship of < em > CYP3A4*1B < /em > Single Nucleotide Polymorphism to the Efficiency and Safety Profiles of Haloperidol in Patients Enduring Acute Alcoholic Hallucinosis
CONCLUSION: The study demonstrated that the 392A > G polymorphism of the CYP3A4*1B gene (rs2740574) in patients with acute alcoholic hallucinosis does not affect the efficacy and safety rates of haloperidol therapy.PMID:38076668 | PMC:PMC10698852 (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - December 11, 2023 Category: Psychiatry & Psychology Authors: A A Parkhomenko M S Zastrozhin VYu Skryabin A E Petukhov S A Pozdniakov V A Ivanchenko I A Zaytsev I V Bure P O Bochkov K A Akmalova V V Smirnov E A Bryun D A Sychev Source Type: research