Editorial Board & Publication Information
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 16, 2018 Category: Psychiatry Source Type: research
Altered tryptophan catabolite concentrations in major depressive disorder and associated changes in hippocampal subfield volumes
The kynurenine pathway (KP) is the major metabolic pathway for tryptophan in the body resulting in the production of kynurenine (KYN) and several downstream metabolites (O ’Farrell and Harkin et al., 2017; Stone et al., 2013). Induction of the rate limiting enzyme in the KP, indolamine 2,3 dioxygenase (IDO) is driven by inflammatory cytokines which has been proposed as a mechanism by which inflammation can precipitate depressive symptoms via tryptophan depletion. Mo st particularly activation of the KP and tryptophan depletion has been observed in depression that occurs secondary to exogenous administration of the cytoki...
Source: Psychoneuroendocrinology - May 15, 2018 Category: Psychiatry Authors: Kelly Doolin, Kelly A. Allers, Sina Pleiner, Andre Liesener, Chloe Farrell, Leonardo Tozzi, Erik O ’Hanlon, Darren Roddy, Thomas Frodl, Andrew Harkin, Veronica O’Keane Source Type: research
The reduced level of growth factors in an animal model of depression is accompanied by regulated necrosis in the frontal cortex but not in the hippocampus
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 14, 2018 Category: Psychiatry Authors: Mateusz Kucharczyk, Anna Kurek, Bartosz Pomierny, Jan Detka, Mariusz Papp, Katarzyna Tota, Bogus ława Budziszewska Source Type: research
Prolonged performance-related neuroendocrine activation and perseverative cognition in low- and high-anxious university music students
Music performance anxiety (MPA) has been defined as “the experience of marked and persistent anxious apprehension related to musical performance […] which is manifested through combinations of affective, cognitive, somatic and behavioral symptoms.” (Kenny, 2010, p. 433). MPA is a major issue for musicians, especially music students (Kaspersen a nd Gotestam, 2002; Patston, 2014). For instance, one third of students of Swiss music universities considered MPA to be a problem, and two thirds expressed the need to receive more support in order to cope better with MPA (Studer et al., 2011). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 14, 2018 Category: Psychiatry Authors: Patrick Gomez, Carole Nielsen, Regina K. Studer, Horst Hildebrandt, Petra L. Klumb, Urs M. Nater, Pascal Wild, Brigitta Danuser Source Type: research
A Peripheral Immune Response to Remembering Trauma Contributes to the Maintenance of Fear Memory in Mice
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 13, 2018 Category: Psychiatry Authors: Matthew B. Young, Leonard L. Howell, Lauren Hopkins, Cassandra Moshfegh, Zhe Yu, Lauren Clubb, Jessica Seidenberg, Jeanie Park, Adam P. Swiercz, Paul J. Marvar Source Type: research
Perceived stress correlates with visceral obesity and lipid parameters of the metabolic syndrome: a systematic review and meta- analysis
Stress is regarded as one of the major public health challenges of the 21st century. Psychological stress has been suggested as a risk factor that may prospectively predict metabolic syndrome (Aschbacher et al., 2014; Pyykkonen et al., 2010). Other studies have also indicated that life stress may lead to metabolic syndrome (Steptoe and Kivim äki, 2013). A cross-sectional study of radiologists demonstrated that professionals characterized by elevated levels of stress had a significantly higher risk of metabolic syndrome than colleagues with lower stress (Magnavita and Fileni, 2014). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 12, 2018 Category: Psychiatry Authors: Judit Tenk, P éter Mátrai, Péter Hegyi, Ildikó Rostás, András Garami, Imre Szabó, Petra Hartmann, Erika Pétervári, László Czopf, Alizadeh Hussain, Mária Simon, Szabina Szujó, Márta Balaskó Source Type: research
Role of apoptosis in the Post-traumatic stress disorder model-single prolonged stressed rats
Post-traumatic stress disorder (PTSD) is a stress-related mental disease which can occur after exposure to serious traumatic events. PTSD patients experience four major symptoms: re-experiencing; avoidance; numbing; and hyperarousal. Magnetic resonance imaging (MRI) studies have identified a reduced volume in the hippocampus of PTSD patients (Bremner et al., 1995; Gilbertson et al., 2002). However, the mechanisms that cause atrophy are not well understood. We focused on the role of apoptosis, which may be associated with atrophy of brain regions in PTSD. (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 12, 2018 Category: Psychiatry Authors: Yunbo Jia, Yunhe Han, Xinyue Wang, Fang Han Source Type: research
Association of T and non-T cell Cytokines with Anhedonia: Role of Gender Differences
Several lines of evidence implicate dysfunctional immune response in the pathophysiology of major depressive disorder (MDD) (Miller and Raison, 2016). Over one-third of patients treated with interferon alpha (an inflammatory cytokine) develop significant depressive symptoms (Raison et al., 2005). Depressive symptoms, in turn, are associated with higher levels of non-specific markers of inflammation such as c-reactive protein (CRP) (Cepeda et al., 2016). Patients with MDD have higher levels of inflammatory cytokines such as interleukin (IL)-6 in peripheral circulation and in cerebrospinal fluid as compared to controls (Kern...
Source: Psychoneuroendocrinology - May 12, 2018 Category: Psychiatry Authors: Manish K. Jha, Andrew H. Miller, Abu Minhajuddin, Madhukar H. Trivedi Source Type: research
Sex hormones affect acute and chronic stress responses in sexually dimorphic patterns: Consequences for depression models
A multitude of different genetic and developmental causes may lead to alterations in a network mediated by stress- and reward-related neurotransmitter and neuromodulator systems, which - in different ways - cause individuals to be vulnerable for depression facing the stressful life events (Bao et al., 2012). The hypothalamo-pituitary-adrenal (HPA) axis is a hub for integrating the neuroendocrine responses to stress (Ramot et al., 2017) and for the pathogenesis of mood disorders (Bao et al., 2005). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 11, 2018 Category: Psychiatry Authors: Lei Guo, Yi-Xi Chen, Yu-Ting Hu, Xue-Yan Wu, Yang He, Juan-Li Wu, Man-Li Huang, Matthew Mason, Ai-Min Bao Source Type: research
Psychosocial stress and inflammation driving tryptophan breakdown in children and adolescents: a cross-sectional analysis of two cohorts
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 11, 2018 Category: Psychiatry Authors: Nathalie Michels, Gerard Clarke, Loreto Olavarria-Ramirez, Sonia G ómez-Martínez, Ligia Esperanza Díaz, Ascensión Marcos, Kurt Widhalm, Livia A. Carvalho Source Type: research
Communication and Social Interaction Anxiety Enhance Interleukin-1 Beta and Cortisol Reactivity during High-Stakes Public Speaking
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 8, 2018 Category: Psychiatry Authors: Brandon J. Auer, Jessica L. Calvi, Nicolas M. Jordan, David Schrader, Jennifer Byrd-Craven Source Type: research
Repositioning of diabetes treatments for depressive symptoms: a systematic review and meta-analysis of clinical trials
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 7, 2018 Category: Psychiatry Authors: Calum D. Moulton, Christopher W.P. Hopkins, Khalida Ismail, Daniel Stahl Source Type: research
Changes in the Tryptophan-Kynurenine Axis in association to therapeutic response in clinically depressed patients undergoing psychiatric rehabilitation
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 6, 2018 Category: Psychiatry Authors: B. Reininghaus, K. Riedrich, N. Dalkner, S.A. Bengesser, A. Birner, M. Platzer, C. Hamm, J.M. Gostner, D. Fuchs, E.Z. Reininghaus Source Type: research
Immune aberrations in children with Autism Spectrum Disorder: a case-control study from a tertiary care neuropsychiatric hospital in India
Autism spectrum disorders (ASD) is a group of heterogeneous neurodevelopmental disorders with persistent deficits in social interaction, language and communication abnormalities and stereotypical behavior (American Psychiatric Association 2013). Recent studies have reported an alarming rise in the prevalence of ASD (Christensen et al., 2016). The pathophysiology of ASD remains unclear and studies have reported association of several genetic and environmental factors (Mefford et al., 2012; Rossignol et al., 2014). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 4, 2018 Category: Psychiatry Authors: Salah Basheer, Manjunatha M. Venkataswamy, Rita Christopher, Therese Van Amelsvoort, Shoba Srinath, Satish Chandra Girimaji, Vasanthapuram Ravi Source Type: research
Sex Differences in the ACTH and Cortisol Response to Pharmacological Probes Are Stressor-Specific and Occur Regardless of Alcohol Dependence History
(Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - May 4, 2018 Category: Psychiatry Authors: Robert M. Anthenelli, Jaimee L. Heffner, Thomas J. Blom, Belinda E. Daniel, Benjamin S. McKenna, Gary S. Wand Source Type: research
