Effect of aripiprazole monotherapy in a patient presenting with delayed sleep phase syndrome associated with depressive symptoms
Abstract Delayed sleep phase syndrome (DSPS) is often complicated by mental symptoms, including depressive symptoms, whereas mood disorder is sometimes accompanied by problems with sleep rhythm, which can make it difficult to treat patients with such symptoms. In daily medical practice, an increased dose of aripiprazole is generally administered when an antidepressant is not sufficiently effective. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - February 1, 2018 Category: Neuroscience Authors: Hidenobu Suzuki, Hiroyuki Hibino, Yuichi Inoue, Katsunaka Mikami Tags: Letter to the Editor Source Type: research

Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain
ConclusionThis finding suggests that the CX3CR1 variants may affect arterial structures in the brain, possibly via interactions between microglia and brain microvascular endothelial cells. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - February 1, 2018 Category: Neuroscience Authors: Mai Sakai, Hikaru Takeuchi, Zhiqian Yu, Yoshie Kikuchi, Chiaki Ono, Yuta Takahashi, Fumiaki Ito, Hiroo Matsuoka, Osamu Tanabe, Jun Yasuda, Yasuyuki Taki, Ryuta Kawashima, Hiroaki Tomita Tags: Regular Article Source Type: research

A survey of recognition and treatment of at ‐risk mental state by Japanese psychiatrists
ConclusionThis study suggested that precise knowledge of at‐risk mental state has not been disseminated among Japanese psychiatrists. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - February 1, 2018 Category: Neuroscience Authors: Naohisa Tsujino, Hiromi Tagata, Yoko Baba, Akiko Kojima, Taiju Yamaguchi, Naoyuki Katagiri, Takahiro Nemoto, Masafumi Mizuno Tags: Regular Article Source Type: research

Understanding the roles of glutamine synthetase, glutaminase, and glutamate decarboxylase autoantibodies in imbalanced excitatory/inhibitory neurotransmission as etiological mechanisms of autism
ConclusionThe obtained data indicate that GS and GLS1 are promising indicators of an E/I imbalance and that combined measured parameters are good predictive biomarkers of autism. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 22, 2018 Category: Neuroscience Authors: Najat O. Hamed, Laila ‐Al‐Ayadhi, Mohamed A. Osman, Elkhawad Abdalla O, Hanan Qasem, Majida Al‐Marshoud, Nada M. Merghani, Afaf El‐Ansary Tags: Regular Article Source Type: research

Therapeutic role of rifampicin in Alzheimer's disease
Psychiatry and Clinical Neurosciences,Volume 72, Issue 3, Page 152-159, March 2018. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 8, 2018 Category: Neuroscience Source Type: research

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Psychiatry and Clinical Neurosciences,Volume 72, Issue 3, Page 152-159, March 2018. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 8, 2018 Category: Neuroscience Source Type: research

Excess incidence and risk factors for recurrent pneumonia in bipolar disorder
ConclusionWe found an excess incidence of recurring pneumonia in patients with bipolar disorder, and this risk was associated with pre‐existing medical conditions but not psychotropic agents. Physicians should carefully consider the comorbid medical conditions of patients with bipolar disorder that could lead to recurrent pneumonia. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 8, 2018 Category: Neuroscience Authors: Min ‐Shan Li, Galen Chin‐Lun Hung, Shu‐Yu Yang, Chun‐Hung Pan, Ya‐Tang Liao, Shang‐Ying Tsai, Chiao‐Chicy Chen, Chian‐Jue Kuo Tags: Regular Article Source Type: research

Japanese Abstract
(Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 4, 2018 Category: Neuroscience Source Type: research

The American Journal of Psychiatry: Table of Contents
(Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 4, 2018 Category: Neuroscience Tags: The American Journal of Psychiatry: Table of Contents Source Type: research

Right treatment for the right schizophrenic patients based on carbonyl stress pathophysiology
(Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 4, 2018 Category: Neuroscience Authors: Norio Ozaki Tags: Editorial Source Type: research

Creativity and arts in psychiatry
(Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 4, 2018 Category: Neuroscience Authors: Yoji Hirano, Kenjiro Hosaka Tags: Editorial Source Type: research

Exercise habit could modulate cognitive benefits from physical and cognitive intervention
Psychiatry and Clinical Neurosciences,Volume 72, Issue 3, Page 189-190, March 2018. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 2, 2018 Category: Neuroscience Source Type: research

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Psychiatry and Clinical Neurosciences,Volume 72, Issue 3, Page 189-190, March 2018. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 2, 2018 Category: Neuroscience Source Type: research

Epigenetics applied to psychiatry: clinical opportunities and future challenges
Abstract Psychiatric disorders are clinically heterogeneous and debilitating chronic diseases resulting from a complex interplay between gene variants and environmental factors. Epigenetic processes, such as DNA methylation and histone posttranslational modifications, instruct the cell/tissue to correctly interpret external signals and adjust its functions accordingly. Given that epigenetic modifications are sensitive to environment, stable and reversible, epigenetic studies in psychiatry could represent a promising approach to better understand and treat disease. In the present review, we aim to discuss the clinical oppor...
Source: Psychiatry and Clinical Neurosciences - January 2, 2018 Category: Neuroscience Authors: Lara Kular, Sonia Kular Tags: Review Article Source Type: research

DNA methylation analyses of the candidate genes identified by a methylome ‐wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder
ConclusionHypomethylation of FAM63B and IR on chromosome 16 could be common epigenetic risk factors for SZ and BD. Further comprehensive epigenetic studies for BD such as MWAS will uncover the extent of similarity and uniqueness of epigenetic alterations. (Source: Psychiatry and Clinical Neurosciences)
Source: Psychiatry and Clinical Neurosciences - January 1, 2018 Category: Neuroscience Authors: Hiroko Sugawara, Yui Murata, Tempei Ikegame, Rie Sawamura, Shota Shimanaga, Yusuke Takeoka, Takeo Saito, Masashi Ikeda, Akane Yoshikawa, Fumichika Nishimura, Yoshiya Kawamura, Chihiro Kakiuchi, Tsukasa Sasaki, Nakao Iwata, Mamoru Hashimoto, Kiyoto Kasai, Tags: Regular Article Source Type: research