Correction to: Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells
Protein Cell. 2023 Dec 19:pwad059. doi: 10.1093/procel/pwad059. Online ahead of print.NO ABSTRACTPMID:38113127 | DOI:10.1093/procel/pwad059 (Source: Protein and Cell)
Source: Protein and Cell - December 19, 2023 Category: Cytology Source Type: research

Cryo-EM structure of cannabinoid receptor CB1- β-arrestin complex
Protein Cell. 2023 Dec 15:pwad055. doi: 10.1093/procel/pwad055. Online ahead of print.NO ABSTRACTPMID:38102480 | DOI:10.1093/procel/pwad055 (Source: Protein and Cell)
Source: Protein and Cell - December 15, 2023 Category: Cytology Authors: Yuxia Wang Lijie Wu Tian Wang Junlin Liu Fei Li Longquan Jiang Zhongbo Fan Yanan Yu Na Chen Qianqian Sun Qiwen Tan Tian Hua Zhi-Jie Liu Source Type: research

Identification of FOXO1 as a geroprotector in human synovium through single-nucleus transcriptomic profiling
Protein Cell. 2023 Dec 13:pwad060. doi: 10.1093/procel/pwad060. Online ahead of print.ABSTRACTThe synovium, a thin layer of tissue that adjacent to the joints and secretes synovial fluid, undergoes changes in aging that contribute to intense shoulder pain and other joint diseases. However, the mechanism underlying human synovial aging remains poorly characterized. Here, we generated a comprehensive profile of synovial cell types present in subacromial synovium from young and aged individuals. By delineating aging-related transcriptomic changes across cell types and their associated regulatory networks, we identified two su...
Source: Protein and Cell - December 13, 2023 Category: Cytology Authors: Feifei Liu Yi Lu Xuebao Wang Shuhui Sun Huize Pan Min Wang Zehua Wang Weiqi Zhang Shuai Ma Guoqiang Sun Qun Chu Si Wang Jing Qu Guang-Hui Liu Source Type: research

Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing
Protein Cell. 2023 Dec 8:pwad058. doi: 10.1093/procel/pwad058. Online ahead of print.NO ABSTRACTPMID:38066594 | DOI:10.1093/procel/pwad058 (Source: Protein and Cell)
Source: Protein and Cell - December 9, 2023 Category: Cytology Authors: Han Chen Mehar Monga Qinghua Fang Loujin Slitin Jakob Neef Shashank S Chepurwar Regina C élia Mingroni Netto Karina Lezirovitz Alfredo Tabith Fritz Benseler Nils Brose Kathrin Kusch Carolin Wichmann Nicola Strenzke Barbara Vona Julia Preobraschenski Tobi Source Type: research

Long way up: rethink diseases in light of phase separation and phase transition
Protein Cell. 2023 Dec 9:pwad057. doi: 10.1093/procel/pwad057. Online ahead of print.ABSTRACTBiomolecular condensation, driven by multivalency, serves as a fundamental mechanism within cells, facilitating the formation of distinct compartments, including membraneless organelles that play essential roles in various cellular processes. Perturbations in the delicate equilibrium of condensation, whether resulting in gain or loss of phase separation, have robustly been associated with cellular dysfunction and physiological disorders. As ongoing research endeavors wholeheartedly embrace this newly acknowledged principle, a trans...
Source: Protein and Cell - December 9, 2023 Category: Cytology Authors: Mingrui Ding Weifan Xu Gaofeng Pei Pilong Li Source Type: research

Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing
Protein Cell. 2023 Dec 8:pwad058. doi: 10.1093/procel/pwad058. Online ahead of print.NO ABSTRACTPMID:38066594 | DOI:10.1093/procel/pwad058 (Source: Protein and Cell)
Source: Protein and Cell - December 9, 2023 Category: Cytology Authors: Han Chen Mehar Monga Qinghua Fang Loujin Slitin Jakob Neef Shashank S Chepurwar Regina C élia Mingroni Netto Karina Lezirovitz Alfredo Tabith Fritz Benseler Nils Brose Kathrin Kusch Carolin Wichmann Nicola Strenzke Barbara Vona Julia Preobraschenski Tobi Source Type: research

Long way up: rethink diseases in light of phase separation and phase transition
Protein Cell. 2023 Dec 9:pwad057. doi: 10.1093/procel/pwad057. Online ahead of print.ABSTRACTBiomolecular condensation, driven by multivalency, serves as a fundamental mechanism within cells, facilitating the formation of distinct compartments, including membraneless organelles that play essential roles in various cellular processes. Perturbations in the delicate equilibrium of condensation, whether resulting in gain or loss of phase separation, have robustly been associated with cellular dysfunction and physiological disorders. As ongoing research endeavors wholeheartedly embrace this newly acknowledged principle, a trans...
Source: Protein and Cell - December 9, 2023 Category: Cytology Authors: Mingrui Ding Weifan Xu Gaofeng Pei Pilong Li Source Type: research

Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing
Protein Cell. 2023 Dec 8:pwad058. doi: 10.1093/procel/pwad058. Online ahead of print.NO ABSTRACTPMID:38066594 | DOI:10.1093/procel/pwad058 (Source: Protein and Cell)
Source: Protein and Cell - December 9, 2023 Category: Cytology Authors: Han Chen Mehar Monga Qinghua Fang Loujin Slitin Jakob Neef Shashank S Chepurwar Regina C élia Mingroni Netto Karina Lezirovitz Alfredo Tabith Fritz Benseler Nils Brose Kathrin Kusch Carolin Wichmann Nicola Strenzke Barbara Vona Julia Preobraschenski Tobi Source Type: research

Long way up: rethink diseases in light of phase separation and phase transition
Protein Cell. 2023 Dec 9:pwad057. doi: 10.1093/procel/pwad057. Online ahead of print.ABSTRACTBiomolecular condensation, driven by multivalency, serves as a fundamental mechanism within cells, facilitating the formation of distinct compartments, including membraneless organelles that play essential roles in various cellular processes. Perturbations in the delicate equilibrium of condensation, whether resulting in gain or loss of phase separation, have robustly been associated with cellular dysfunction and physiological disorders. As ongoing research endeavors wholeheartedly embrace this newly acknowledged principle, a trans...
Source: Protein and Cell - December 9, 2023 Category: Cytology Authors: Mingrui Ding Weifan Xu Gaofeng Pei Pilong Li Source Type: research