Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain
Protein Cell. 2023 Jul 4:pwad041. doi: 10.1093/procel/pwad041. Online ahead of print.NO ABSTRACTPMID:37402638 | DOI:10.1093/procel/pwad041 (Source: Protein and Cell)
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Juan Zhang Dingfeng Li Keqiang He Qiang Liu Zhongwen Xie Source Type: research
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium
Protein Cell. 2023 Jun 7;14(6):433-447. doi: 10.1093/procel/pwac059.ABSTRACTMolecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and single-cell assay for transposase accessible chromatin sequencing (scATAC-seq) techniques, we uncovered the spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Specifically, we identified a stem/progenitor cell population in the isthmus of human gastric corpus, where EGF and WNT signaling pathways were activated. Meanwhil...
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Ji Dong Xinglong Wu Xin Zhou Yuan Gao Changliang Wang Wendong Wang Weiya He Jingyun Li Wenjun Deng Jiayu Liao Xiaotian Wu Yongqu Lu Antony K Chen Lu Wen Wei Fu Fuchou Tang Source Type: research
Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain
Protein Cell. 2023 Jul 4:pwad041. doi: 10.1093/procel/pwad041. Online ahead of print.NO ABSTRACTPMID:37402638 | DOI:10.1093/procel/pwad041 (Source: Protein and Cell)
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Juan Zhang Dingfeng Li Keqiang He Qiang Liu Zhongwen Xie Source Type: research
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium
Protein Cell. 2023 Jun 7;14(6):433-447. doi: 10.1093/procel/pwac059.ABSTRACTMolecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and single-cell assay for transposase accessible chromatin sequencing (scATAC-seq) techniques, we uncovered the spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Specifically, we identified a stem/progenitor cell population in the isthmus of human gastric corpus, where EGF and WNT signaling pathways were activated. Meanwhil...
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Ji Dong Xinglong Wu Xin Zhou Yuan Gao Changliang Wang Wendong Wang Weiya He Jingyun Li Wenjun Deng Jiayu Liao Xiaotian Wu Yongqu Lu Antony K Chen Lu Wen Wei Fu Fuchou Tang Source Type: research
Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain
Protein Cell. 2023 Jul 4:pwad041. doi: 10.1093/procel/pwad041. Online ahead of print.NO ABSTRACTPMID:37402638 | DOI:10.1093/procel/pwad041 (Source: Protein and Cell)
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Juan Zhang Dingfeng Li Keqiang He Qiang Liu Zhongwen Xie Source Type: research
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium
Protein Cell. 2023 Jun 7;14(6):433-447. doi: 10.1093/procel/pwac059.ABSTRACTMolecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and single-cell assay for transposase accessible chromatin sequencing (scATAC-seq) techniques, we uncovered the spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Specifically, we identified a stem/progenitor cell population in the isthmus of human gastric corpus, where EGF and WNT signaling pathways were activated. Meanwhil...
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Ji Dong Xinglong Wu Xin Zhou Yuan Gao Changliang Wang Wendong Wang Weiya He Jingyun Li Wenjun Deng Jiayu Liao Xiaotian Wu Yongqu Lu Antony K Chen Lu Wen Wei Fu Fuchou Tang Source Type: research
Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain
Protein Cell. 2023 Jul 4:pwad041. doi: 10.1093/procel/pwad041. Online ahead of print.NO ABSTRACTPMID:37402638 | DOI:10.1093/procel/pwad041 (Source: Protein and Cell)
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Juan Zhang Dingfeng Li Keqiang He Qiang Liu Zhongwen Xie Source Type: research
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium
Protein Cell. 2023 Jun 7;14(6):433-447. doi: 10.1093/procel/pwac059.ABSTRACTMolecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and single-cell assay for transposase accessible chromatin sequencing (scATAC-seq) techniques, we uncovered the spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Specifically, we identified a stem/progenitor cell population in the isthmus of human gastric corpus, where EGF and WNT signaling pathways were activated. Meanwhil...
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Ji Dong Xinglong Wu Xin Zhou Yuan Gao Changliang Wang Wendong Wang Weiya He Jingyun Li Wenjun Deng Jiayu Liao Xiaotian Wu Yongqu Lu Antony K Chen Lu Wen Wei Fu Fuchou Tang Source Type: research
Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain
Protein Cell. 2023 Jul 4:pwad041. doi: 10.1093/procel/pwad041. Online ahead of print.NO ABSTRACTPMID:37402638 | DOI:10.1093/procel/pwad041 (Source: Protein and Cell)
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Juan Zhang Dingfeng Li Keqiang He Qiang Liu Zhongwen Xie Source Type: research
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium
Protein Cell. 2023 Jun 7;14(6):433-447. doi: 10.1093/procel/pwac059.ABSTRACTMolecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and single-cell assay for transposase accessible chromatin sequencing (scATAC-seq) techniques, we uncovered the spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Specifically, we identified a stem/progenitor cell population in the isthmus of human gastric corpus, where EGF and WNT signaling pathways were activated. Meanwhil...
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Ji Dong Xinglong Wu Xin Zhou Yuan Gao Changliang Wang Wendong Wang Weiya He Jingyun Li Wenjun Deng Jiayu Liao Xiaotian Wu Yongqu Lu Antony K Chen Lu Wen Wei Fu Fuchou Tang Source Type: research
Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain
Protein Cell. 2023 Jul 4:pwad041. doi: 10.1093/procel/pwad041. Online ahead of print.NO ABSTRACTPMID:37402638 | DOI:10.1093/procel/pwad041 (Source: Protein and Cell)
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Juan Zhang Dingfeng Li Keqiang He Qiang Liu Zhongwen Xie Source Type: research
Spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium
Protein Cell. 2023 Jun 7;14(6):433-447. doi: 10.1093/procel/pwac059.ABSTRACTMolecular knowledge of human gastric corpus epithelium remains incomplete. Here, by integrated analyses using single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and single-cell assay for transposase accessible chromatin sequencing (scATAC-seq) techniques, we uncovered the spatially resolved expression landscape and gene-regulatory network of human gastric corpus epithelium. Specifically, we identified a stem/progenitor cell population in the isthmus of human gastric corpus, where EGF and WNT signaling pathways were activated. Meanwhil...
Source: Protein and Cell - July 4, 2023 Category: Cytology Authors: Ji Dong Xinglong Wu Xin Zhou Yuan Gao Changliang Wang Wendong Wang Weiya He Jingyun Li Wenjun Deng Jiayu Liao Xiaotian Wu Yongqu Lu Antony K Chen Lu Wen Wei Fu Fuchou Tang Source Type: research
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines
Protein Cell. 2023 Jun 28;14(7):532-537. doi: 10.1093/procel/pwac028.NO ABSTRACTPMID:37378658 | PMC:PMC10305735 | DOI:10.1093/procel/pwac028 (Source: Protein and Cell)
Source: Protein and Cell - June 28, 2023 Category: Cytology Authors: Ya-Hui Zhao Wei Jiang Hai Gao Guo-Zheng Pang Yu-Shuang Wu Yuan-Xian Wang Meng-Yao Sheng Jia-Ying Xie Wan-Ling Wu Zhi-Jian Ji Ya-Rui Du Lei Zhang Xiao-Qin Wang Colum P Walsh Hai Jiang Guo-Liang Xu Dan Zhou Source Type: research
An engineered xCas12i with high activity, high specificity, and broad PAM range
Protein Cell. 2023 Jun 28;14(7):538-543. doi: 10.1093/procel/pwac052.NO ABSTRACTPMID:37378659 | PMC:PMC10305737 | DOI:10.1093/procel/pwac052 (Source: Protein and Cell)
Source: Protein and Cell - June 28, 2023 Category: Cytology Authors: Hainan Zhang Xiangfeng Kong Mingxing Xue Jing Hu Zikang Wang Yinghui Wei Haoqiang Wang Jingxing Zhou Weihong Zhang Mengqiu Xu Xiaowen Shen Fengcai Yin Zhiyuan Ai Guangyan Huang Junhui Xia Xueqiong Song Hengbin Li Yuan Yuan Jinhui Li Na Zhong Meiling Zhang Source Type: research
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes
This study expands our knowledge of primate liver aging and informs the development of diagnostics and therapeutic interventions for liver aging and associated diseases.PMID:37378670 | DOI:10.1093/procel/pwad039 (Source: Protein and Cell)
Source: Protein and Cell - June 28, 2023 Category: Cytology Authors: Shanshan Yang Chengyu Liu Mengmeng Jiang Xiaoqian Liu Lingling Geng Yiyuan Zhang Shuhui Sun Kang Wang Jian Yin Shuai Ma Si Wang Juan Carlos Izpisua Belmonte Weiqi Zhang Jing Qu Guang-Hui Liu Source Type: research
