[Comparison between endoscopic stenting and colostomy in the management of obstructing cancer of the left colon: Literature review].
CONCLUSION: In case of neoplastic occlusion of the left colon, the choice between colostomy or colonic stent depends on the therapeutic strategy. Indeed, for curative strategy or administration of anti-angiogenics, it is recommended to practice a colostomy. However, for palliative treatment, colonic stenting is the treatment to follow. PMID: 30799150 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - February 21, 2019 Category: General Medicine Authors: Trigui A, Rejab H, Akrout A, Harbi H, Kachaou A, Fendri S, Frikha MF, Mzali R Tags: Presse Med Source Type: research

[Heart failure in patients over 80 years old].
Abstract Heart failure (HF) is a clinical syndrome that associates clinical signs in people over 80 years of age, an increase in natriuretic peptides and abnormal cardiac structures that result from cardiac aging in many cases. The most common symptoms are grouped according to the acronym "EPOF" (shortness of breath, weight gain, edema, fatigue). Over the age of 80, comorbidities must be taken into account. The incidence and prevalence of HF significantly increases with age and makes HF the most common reason for hospitalization for people over 80, and an important health expense. The management of HF, n...
Source: Presse Medicale - February 21, 2019 Category: General Medicine Authors: Berthelot E, Nouhaud C, Lafuente-Lafuente C, Assayag P, Hittinger L Tags: Presse Med Source Type: research

[Health students quality of life: A challenge for universities].
cute; PMID: 30773252 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - February 14, 2019 Category: General Medicine Authors: Diot P, Arnault É Tags: Presse Med Source Type: research

[Prevalence and risk markers of anxiety and depression among health students].
lon L PMID: 30770277 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - February 12, 2019 Category: General Medicine Authors: Hermetet C, Arnault É, Gaborit C, Coillot H, Florence AM, Diot P, Colombat P, Rusch E, Grammatico-Guillon L Tags: Presse Med Source Type: research

Intervention psychoth érapeutique brève (activation comportementale) pour le traitement de la dépression d’intensité légère à modérée en soins primaires : proposition d’un guide pour la pratique clinique.
Intervention psychothérapeutique brève (activation comportementale) pour le traitement de la dépression d’intensité légère à modérée en soins primaires : proposition d’un guide pour la pratique clinique. Presse Med. 2019 Feb 12;: Authors: Sarron PY, Palma J, Lemaire M, Camus V, ElHage W PMID: 30770278 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - February 12, 2019 Category: General Medicine Authors: Sarron PY, Palma J, Lemaire M, Camus V, ElHage W Tags: Presse Med Source Type: research

[An high level diagnosis!]
PMID: 30737074 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - February 6, 2019 Category: General Medicine Authors: Kauffmann P, Le Borgne P, Lemaitre EL, Quoirin E, Bilbault P Tags: Presse Med Source Type: research

[Hypotensions in the elderly: Clinical and therapeutic features].
Abstract Hypotension and especially very low diastolic blood pressure could be an at-risk situation in very old and frail patients and in those with coronary heart disease. Chronic hypotension in people with heart failure is an indicator of poor prognosis and hinders the management of therapy. Orthostatic hypotension is a decrease in blood pressure>20mmHg for systolic and/or>10mmHg for diastolic within 3minutes after transition from supine to upright. Orthostatic hypotension may be symptomatic or not. The search for orthostatic hypotension is part of the clinical examination of elderly patients with hyperten...
Source: Presse Medicale - February 3, 2019 Category: General Medicine Authors: Magny E, Donadio C, Maronnat F, Nghiem D, Berthelot E, Belmin J, Lafuente-Lafuente C Tags: Presse Med Source Type: research

[Childhood trauma in subjects at ultra high risk for psychosis].
Abstract Childhood adversity rates would be higher in subjects at ultra-high risk of psychosis than in the general population. In addition to reference ideas, magical thoughts and social dysfunction, subjects at ultra-high risk of psychosis with a history of childhood trauma would experience more severe and specific symptoms. Childhood trauma, especially sexual abuse, was associated with the transition to psychosis. Several models have been cited to explain the link between trauma and the subsequent onset of psychosis or prepsychotic states: dysfunctional cognitive patterns, affective dysregulation, attachment sty...
Source: Presse Medicale - January 30, 2019 Category: General Medicine Authors: Fekih-Romdhane F, Ben Fadhel S, Hakiri A, Cheour M Tags: Presse Med Source Type: research

[Update of French guidelines for the use of positron emission tomography (PET) in gastro-intestinal cancer (Part of the InCa guidelines)].
PMID: 30709559 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 29, 2019 Category: General Medicine Authors: Wartski M, Coriat R Tags: Presse Med Source Type: research

Familial Mediterranean Fever.
Abstract Familial Mediterranean Fever (FMF) is the oldest and the most frequent of all described hereditary periodic fever syndromes. The populations originating from Mediterranean basin carry the highest risk for FMF however it is being increasingly recognized in many parts of the world. It is an autoinflammatory disease with an autosomal recessive transmission. In the majority of the patients it is related with mutations in the MEFV gene that encodes a protein named pyrin. This protein has been shown to act as a regulator of inflammation mediated by IL-1β, which plays a major role in the pathogenesis of FMF...
Source: Presse Medicale - January 24, 2019 Category: General Medicine Authors: Ozdogan H, Ugurlu S Tags: Presse Med Source Type: research

Autoinflammatory diseases: State of the art.
Abstract Autoinflammatory diseases are characterized by innate immunity abnormalities. In autoinflammatory diseases (AID), inflammatory blood biomarkers are elevated during crisis without infection and usually without autoantibodies. The first 4 described AID were familial Mediterranean fever, cryopyrin-associated periodic fever syndrome (CAPS) or NLRP3-associated autoinflammatory disease (NRLP3-AID), mevalonate kinase deficiency (MKD) and TNFRSF1A-receptor associated periodic fever syndrome (TRAPS). Since their description 20 years ago, and with the progresses of genetic analysis, many new diseases have been disc...
Source: Presse Medicale - January 24, 2019 Category: General Medicine Authors: Georgin-Lavialle S, Fayand A, Rodrigues F, Bachmeyer C, Savey L, Grateau G Tags: Presse Med Source Type: research

[Suicide in prison: Epidemiology and prevention].
Abstract Suicide is one of the most important causes of death in prison around the world. In France, suicide rate for prisoners is 18.5 suicides per 10,000 inmates: seven times more common than in the general population. Among the risk factors identified in the literature, those most strongly associated with suicide in prison are physical isolation in custody, psychiatric history and history of suicide attempts. The prevention of suicide in prison involves several measures including treatment of psychiatric disorders, improvement of living conditions in custody, social support of prisoners and use of specific tool...
Source: Presse Medicale - January 23, 2019 Category: General Medicine Authors: Eck M, Scouflaire T, Debien C, Amad A, Sannier O, Chan Chee C, Thomas P, Vaiva G, Fovet T Tags: Presse Med Source Type: research

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome - PFAPA syndrome.
Abstract Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is a complex autoinflammatory disease with a clinical phenotype characterised by recurrent episodes of fever, systemic inflammation and symptoms and signs depicted in disease acronym. Although PFAPA is the most common autoinflammatory disease among children in many parts of the world, the condition is still an enigma, which include the regular episodes, the prompt responses to corticosteroids, the genetic bases for the familial clustering and therapeutic effects of tonsillectomy. This review explores PFAPA syndrome wi...
Source: Presse Medicale - January 22, 2019 Category: General Medicine Authors: Wekell P Tags: Presse Med Source Type: research

[Prevalence of major depression in France in the general population and in specific populations from 2000 to 2018: A systematic review of the literature].
Abstract OBJECTIVE: To synthetize the data on the prevalence of major depressive disorders (MDD) in France in general population and in specific populations. METHOD: A systematic review following the PRISMA criteria has been carried out. MEDLINE, google scholar, Isi web of science, PsychInfo et Cochrane library have been explored, from 2000 to April 2018. RESULTS: The prevalence of major depression in France over the last 12 months was around 8% in the 2000s and seems to have increased to 10% in the 2010s. Studies on national databases tend to underestimate this prevalence (
Source: Presse Medicale - January 21, 2019 Category: General Medicine Authors: Fond G, Lancon C, Auquier P, Boyer L Tags: Presse Med Source Type: research

Autoinflammatory syndromes.
PMID: 30665787 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 19, 2019 Category: General Medicine Authors: Georgin-Lavialle S, Savey L, Grateau G Tags: Presse Med Source Type: research

[Essential hypertension: Definitions, hemodynamic, clinical and therapeutic review].
her J Abstract Arterial hypertension is à chronic disease that affects more than 25 % of the French adult population. Increased peripheral resistance combined with normal cardiac output is a special feature of arterial hypertension. The increase in the resistance of arterioles remains an important feature of arterial hypertension while the study of the rigidity of large arterials trunks remains poorly explored. Pulse wave velocity (PWV) measurement has been established as one of the major independent predictors of cardiovascular events in arterial hypertension. PMID: 30665781 [PubMed - as supplied...
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Vallée A, Safar ME, Blacher J Tags: Presse Med Source Type: research

[Relapse of acute rheumatism fever associated with acute post-streptococcal glomerulonephritis].
PMID: 30665782 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Langlois ME, Oehler E Tags: Presse Med Source Type: research

How to prescribe a genetic test for the diagnosis of autoinflammatory diseases?
Abstract The systemic autoinflammatory disorders (SAIDs) are associated with dysregulation of the innate immune system, affecting pro-inflammatory cytokines and apoptosis pathways. The spectrum of SAIDs continues to grow with over 30 different disorders identified to date. The main indication for genetic referral is when a patient presents with clinical symptoms consistent with one or more of the SAIDs. Thus, in making a referral for DNA screening, clinical information that supports the choice for screening of one or more SAIDs genes is required. Many of the SAIDs can display overlapping, partial or atypical sympt...
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Rowczenio DM, Lachmann HJ Tags: Presse Med Source Type: research

[Training to welcome families in intensive care unit by serious game].
PMID: 30665784 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Parmentier-Decrucq E, Bouamria N, Bouzeriba M, Jourdain M Tags: Presse Med Source Type: research

[About a lymphatic lumbago].
PMID: 30665785 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Zamani O, Boukhalit H, Moatassim Billah N, Ittimade N Tags: Presse Med Source Type: research

[Asthma exacerbations in adults: Preventing and treat].
te; C Abstract Exacerbations of asthma are still responsible for 900 deaths per year in France, most of which are considered preventable. They have a major impact on the quality of life of patients and are responsible for a large part of the socio-economic cost of asthma in France. Exacerbations of asthma can be partly prevented by inhaled corticosteroid treatment as controller therapy, at a dose adapted to the level of control of symptoms and the management of aggravating factors. Every patient should benefit from a written action plan that allows them to start oral corticosteroid therapy as soon as possible duri...
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Mahay G, Le Brun M, Taillé C Tags: Presse Med Source Type: research

[Hypertension in the elderly].
Abstract After 80 years old, antihypertensive treatment significantly reduces cardiovascular events. In the elderly, blood pressure target depends on patients' frailty. After 80 years, French guidelines propose to aim a SBP
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Hernandorena I, Bailly H, Piccoli M, Beunardeau M, Cohen A, Hanon O Tags: Presse Med Source Type: research

[Ischemic stroke post varicella angiopathy in children].
PMID: 30665789 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Azizi M, Rkain M, Benajiba N, Babakhouya A Tags: Presse Med Source Type: research

[Aspirin and preeclampsia].
Abstract Indications for aspirin during pregnancy are a matter of debate and there is a recent trend to an extended prescription and an overuse of aspirin in pregnancy. Aspirin is efficient in secondary prevention of preeclampsia essentially in patients with a personal history of preeclampsia. The effect of aspirin on platelet aggregation and on the TXA2/PGI2 balance is dose-dependent. The optimum dosage, from 75mg/day to 150mg/day, needs to be determined. Fetal safety data at 150mg/day are still limited. The efficacy of aspirin seems to be subject to a chronobiological effect. It is recommended to prescribe an ev...
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Atallah A, Lecarpentier E, Goffinet F, Gaucherand P, Doret-Dion M, Tsatsaris V Tags: Presse Med Source Type: research

[The impact of periodontal therapy on the diabetes control: A systematic review].
CONCLUSION: The results of this systematic review indicate that periodontal therapy can contribute to diabetes control in diabetic patients with periodontitis. PMID: 30665791 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Benrachadi L, Mohamed Saleh Z, Bouziane A Tags: Presse Med Source Type: research

[Neuro-lupus revealed by a hemiparesis and abnormal movements of a teenager].
lin T PMID: 30665792 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Charbonnier G, Béreau M, Bonnet L, Medeiros de Bustos E, Vuillier F, Moulin T Tags: Presse Med Source Type: research

[Cutaneous abscesses with streptomyces rectiverticillatus during an interleukin 12 deficiency].
PMID: 30665793 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Zayet S, Berriche A, Battikh H, Zribi M, Fendri C, Benaissa HT Tags: Presse Med Source Type: research

Bilateral simultaneous central retinal vein occlusion revealing Waldenstr öm's macroglobulinemia.
Bilateral simultaneous central retinal vein occlusion revealing Waldenström's macroglobulinemia. Presse Med. 2019 Jan 18;: Authors: Kammoun S, Kilani W, Abid F, Ben Amor S, Feki J PMID: 30665794 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 18, 2019 Category: General Medicine Authors: Kammoun S, Kilani W, Abid F, Ben Amor S, Feki J Tags: Presse Med Source Type: research

[Unusual mechanism of myocardial infarction in infective endocarditis].
PMID: 30661719 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - January 17, 2019 Category: General Medicine Authors: Messaoudi Y Tags: Presse Med Source Type: research

[Surgical repair of the sequelae of simultaneous burns of the four eyelids].
PMID: 30551932 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 11, 2018 Category: General Medicine Authors: Ghorbel I, Bellaaj H, Karra A, Fourati A, Ennouri K Tags: Presse Med Source Type: research

[A splenic tendonitis ?]
PMID: 30551933 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 11, 2018 Category: General Medicine Authors: Tbouda M, Toufga Z, Jahid A, Bourhoum N, Zouaidia F, Bernoussi Z Tags: Presse Med Source Type: research

Dubin-Johnson syndrome in Tunisia: Spectrum of a rare disease.
PMID: 30545689 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 10, 2018 Category: General Medicine Authors: Guirat N, Abdelhedi F, Tfifha M, Charfi A, Sticova E, Jirsa M Tags: Presse Med Source Type: research

[Aortic stenosis in the elderly: The TAVI revolution].
Abstract TAVI is currently recommended for severe symptomatic aortic stenosis in patients at prohibitive, high or intermediate surgical risk as estimated by surgical risk scores (STS score and EuroSCORE II). Comorbidity, technical feasibility of TAVI and concurrent pathology with need for complementary surgical correction are conditions to be considered to choose between open surgery and TAVI. The decision is often made by the "Heart Team". The transfemoral access must be favored. Conduction disturbance, stroke, bioprosthesis thrombosis and durability are the main setbacks of TAVI. Double antiplatelet th...
Source: Presse Medicale - December 10, 2018 Category: General Medicine Authors: Overtchouk P, Collet JP Tags: Presse Med Source Type: research

[Retroperitoneal leiomyosarcoma in adult].
PMID: 30545691 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 10, 2018 Category: General Medicine Authors: Balti M, Ayari J, Ben Azaiez M, Fendri S, Ghorbel L, Haddaoui A Tags: Presse Med Source Type: research

Cutaneous vasculitis preceding the onset of anti-GBM disease (Goodpasture syndrome).
PMID: 30545692 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 10, 2018 Category: General Medicine Authors: Kluger N Tags: Presse Med Source Type: research

[Biological function and dysfunction today: From the perspective of Georges Canguilhem].
PMID: 30528144 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Simon F, Braunstein JF Tags: Presse Med Source Type: research

LPAC syndrome: An uncommon etiology of intrahepatic cholelithiasis.
PMID: 30528145 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Medhioub M, Ayedi H, Hamzaoui ML, Khsiba A, Mahmoudi M, Azzouz MM Tags: Presse Med Source Type: research

[Dramatic improvement after decompressive craniectomy in a fulminant stroke-like case of herpes simplex encephalitis].
PMID: 30528146 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Sellier A, Joubert C, Desse N, Bernard C, Faivre A, Dagain A Tags: Presse Med Source Type: research

[Treatment with oral anticoagulants in older patients: Should warfarin still be prescribed?]
Abstract Vitamin-K antagonists (VKA) have been the standard for oral anticoagulation. However, they carry several problems in older patients: frequent bleeding complications, complex management, risk of interactions with multiple drugs. Two classes of direct oral anticoagulants (DOA) are currently available in France: (a) direct thrombin inhibitors: dabigatran; and (b) direct factor Xa inhibitors: rivaroxaban, apixaban and others. Their management is easier: quickly effective after administration, they are given at fixed doses and do not need regular laboratory monitoring. Several randomized trials have shown that...
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Lafuente-Lafuente C, Oasi C, Belmin J Tags: Presse Med Source Type: research

Health care services and disease modifying therapies use in community-based multiple sclerosis patients: Evolution from 2013 to 2015 and demographic characteristics.
aud H Abstract INTEREST OF THE WORK: Multiple sclerosis (MS) disease modifying therapies (DMT) utilization increased during the last decade with the approval of new drugs. Symptomatic treatments also play an important role. Describing time trends and demographic characteristics for DMT and symptomatic treatments utilization in population-based MS patients will lead to a better knowledge of the resources distribution. METHODS: Repeated cross-sectional analysis on each calendar year were implemented retrospectively on the health insurance claims database in France from 2013 until 2015 regarding DMT, fampridine,...
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Ha-Vinh P, Nauleau S, Clementz M, Régnard P, Sauze L, Clavaud H Tags: Presse Med Source Type: research

Tattooing and multiple sclerosis: A study among 445 French patients.
PMID: 30528149 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Kluger N Tags: Presse Med Source Type: research

High-degree atrioventricular block revealing hypertrophic cardiomyopathy related to a mutation in MYBPC3 gene.
eau F PMID: 30528150 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Kouakam C, Boulé S, Brigadeau F Tags: Presse Med Source Type: research

Piezogenic pedal papules.
tte E PMID: 30528151 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: André R, Laffitte E Tags: Presse Med Source Type: research

[Alpha chain disease: From bedside to bench and back again, an exemplary translation].
PMID: 30528152 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - December 7, 2018 Category: General Medicine Authors: Matuchansky C Tags: Presse Med Source Type: research

The 2016 World Health Organization classification of tumours of the central nervous system.
Abstract The 2016 WHO classification of tumours of the central nervous system represents the new paradigm among the specialists in the brain tumours and proposes a new approach combining histopathological and molecular features into diagnosis named 'integrated diagnosis'. The aim of this challenge is to overstep the interobserver variability of diagnosis based on previous classifications in order to ensure homogenous biological entities with a more accurate clinical significance. Over the last two decades, several molecular aberrations into gliomagenesis were highlighted and then confirmed as emerging biomarkers t...
Source: Presse Medicale - November 15, 2018 Category: General Medicine Authors: Villa C, Miquel C, Mosses D, Bernier M, Di Stefano AL Tags: Presse Med Source Type: research

Management of meningioma.
Abstract Meningiomas are the most frequent primary brain tumors, accounting for ∼37% of central nervous systems tumors. Despite being largely benign, clinicians frequently face difficult treatment decisions in cases with complex morphology or localisation, near vital brain structures such as the optic nerve or in the case of incidental tumors. Here, we review current concepts of diagnosis, treatment and follow-up with clinical decision-making informed by multimodal imaging, histology, and molecular biology. PMID: 30449639 [PubMed - as supplied by publisher] (Source: Presse Medicale)
Source: Presse Medicale - November 15, 2018 Category: General Medicine Authors: Euskirchen P, Peyre M Tags: Presse Med Source Type: research

[Shift-workers and night-workers' medical watching and prevention: State of art and recommendations].
cine du sommeil (SFRMS) Abstract Night work is not only a work performed at night. It has also to be considered as a specifically organized work with its own duties and moving tasks in a different relational context. Primary preventive assessments regarding work schedules and occupational associated constraints have to be considered beside family potential consequences. Taking account of the consensually accepted impact of night-shift work on health, particularly on sleep, we recommend an annual medical visit for night-shift workers. We also recommend to declare the night shift diseases to the Regional committee o...
Source: Presse Medicale - November 13, 2018 Category: General Medicine Authors: Metlaine A, Leger D, Esquirol Y, et le Groupe consensus chronobiologie et sommeil de la Société française de recherche et médecine du sommeil (SFRMS) Tags: Presse Med Source Type: research

[Shift-workers and night-workers' health consequences: State of art and recommendations].
cine du sommeil (SFRMS) Abstract There are in France several millions of shift-workers and night-workers (20 to 25% of employees). These workers are therefore subject to variations in their working and rest schedules. These regular schedule changes are associated with repeated desynchronization of circadian biological clock. The negative impacts on sleep are insomnia, drowsiness, and reduced sleep time in 24hours. There is also a proven effect on the occurrence of a metabolic syndrome, with a likely effect on obesity, type 2 diabetes, blood pressure and coronary artery disease. There is a likely effect on the occu...
Source: Presse Medicale - November 13, 2018 Category: General Medicine Authors: Leger D, Esquirol Y, Gronfier C, Metlaine A, Groupe consensus chronobiologie et sommeil de la Société française de recherche et médecine du sommeil (SFRMS) Tags: Presse Med Source Type: research

Management of primary central nervous system lymphoma.
Abstract A rare tumor, primary central nervous system lymphoma can affect immunocompetent and immunocompromised patients. While sensitive to radiotherapy or chemotherapy crossing the blood-brain barrier, it often recurs. Modern treatment consists of high-dose methotrexate-based induction chemotherapy, often followed by consolidation with either radiotherapy or further chemotherapy. Neurotoxicity is however a concern with radiotherapy, especially for patients older than 60 years. The benefit of the addition of rituximab to chemotherapy is unclear. Targeted therapies and immunotherapy have been effective in some pat...
Source: Presse Medicale - November 8, 2018 Category: General Medicine Authors: Royer-Perron L, Hoang-Xuan K Tags: Presse Med Source Type: research

Diagnostic biologique des angioed èmes bradykiniques : les recommandations du CREAK.
Diagnostic biologique des angioedèmes bradykiniques : les recommandations du CREAK. Presse Med. 2018 Nov 08;: Authors: Bouillet L, Defendi F, Hardy G, Cesbron JY, Boccon-Gibod I, Deroux A, Mansard C, Launay D, Gompel A, Floccard B, Jaussaud R, Beaudouin E, Armengol G, Olliver Y, Gayet S, Du Than A, Sailler L, Guez S, Sarrat A, Sorin L, de Moreuil C, Pelletier F, Javaud N, Marmion N, Fain O, Fauré J, Dumestre-Pérard C Abstract Bradykinin mediated angioedema (BK-AE) can be associated either with C1Inhibitor deficiency (hereditary and acquired forms), either with normal C1Inh (h...
Source: Presse Medicale - November 8, 2018 Category: General Medicine Authors: Bouillet L, Defendi F, Hardy G, Cesbron JY, Boccon-Gibod I, Deroux A, Mansard C, Launay D, Gompel A, Floccard B, Jaussaud R, Beaudouin E, Armengol G, Olliver Y, Gayet S, Du Than A, Sailler L, Guez S, Sarrat A, Sorin L, de Moreuil C, Pelletier F, Javaud N, Tags: Presse Med Source Type: research