Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research
Diagnostic Criteria and Etiopathogenesis of Type 2 Diabetes and Its Complications: Lessons from the Pima Indians
Presse Med. 2023 Sep 30:104176. doi: 10.1016/j.lpm.2023.104176. Online ahead of print.ABSTRACTThe Phoenix Epidemiology and Clinical Research Branch of the National Institute of Diabetes and Digestive and Kidney Diseases has conducted prospective studies of diabetes and its complications in the Pima Indians living in Arizona, USA for over 50 years. In this review we highlight areas in which these studies provided vital insights into the criteria used to diagnose type 2 diabetes, the pathophysiologic changes that accompany the development of type 2 diabetes, and the course and determinants of diabetes complications-focusing ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Helen C Looker Douglas C Chang Leslie J Baier Robert L Hanson Robert G Nelson Source Type: research
Clinical Trials with reno-vascular end points in patients with diabetes: Changing the scenario over the past 20 years
Presse Med. 2023 Sep 30:104178. doi: 10.1016/j.lpm.2023.104178. Online ahead of print.ABSTRACTMajor clinical advances over the last 25 years in the area of diabetic kidney disease (DKD) have been confirmed in large seminal clinical trials. These findings add to the previously identified benefits resulting from intensive glucose and blood pressure control therapies. Furthermore, newer glucose lowering treatments such as SGLT2 inhibitors and GLP-1 agonists appear very promising and are likely to transform the management and outlook of DKD over the next decade. In addition, newer mineralocorticoid receptor antagonists and a r...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Tomasz J Block Mark E Cooper Source Type: research
Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research
Bronchiectasis
Presse Med. 2023 Sep 29:104174. doi: 10.1016/j.lpm.2023.104174. Online ahead of print.ABSTRACTBronchiectasis is a final common pathway of a wide variety of underlying conditions including infectious, autoimmune, allergic, genetic and inflammatory conditions. Patients experience a chronic disease with variable clinical symptoms and course, but most experience cough, sputum production and recurrent exacerbations. Symptoms of bronchiectasis lead to poor quality of life and exacerbations are the major driver of morbidity and mortality. Patients are often chronically infected with bacteria with the most common being Pseudomonas...
Source: Presse Medicale - October 1, 2023 Category: General Medicine Authors: Miguel Barbosa James D Chalmers Source Type: research
The European reference network on rare lung diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10;52(3):104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European reference network on rare lung diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10;52(3):104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European reference network on rare lung diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10;52(3):104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
The European Reference Network on Rare Lung Diseases (ERN-LUNG) ambition to offer better lung health for all
Presse Med. 2023 Sep 10:104172. doi: 10.1016/j.lpm.2023.104172. Online ahead of print.NO ABSTRACTPMID:37699508 | DOI:10.1016/j.lpm.2023.104172 (Source: Presse Medicale)
Source: Presse Medicale - September 12, 2023 Category: General Medicine Authors: Marc Humbert Thomas Wagner Source Type: research
