Prognosis of Consciousness Disorders in the Intensive Care Unit
Presse Med. 2023 Oct 5:104180. doi: 10.1016/j.lpm.2023.104180. Online ahead of print.ABSTRACTAssessments of consciousness are a critical part of prognostic algorithms for critically ill patients suffering from severe brain injuries. There have been significant advances in the field of coma science over the past two decades, providing clinicians with more advanced and precise tools for diagnosing and prognosticating disorders of consciousness (DoC). Advanced neuroimaging and electrophysiological techniques have vastly expanded our understanding of the biological mechanisms underlying consciousness, and have helped identify ...
Source: Presse Medicale - October 7, 2023 Category: General Medicine Authors: Aditya Kumar Mohamed Ridha Jan Claassen Source Type: research
Prognosis of Consciousness Disorders in the Intensive Care Unit
Presse Med. 2023 Oct 5:104180. doi: 10.1016/j.lpm.2023.104180. Online ahead of print.ABSTRACTAssessments of consciousness are a critical part of prognostic algorithms for critically ill patients suffering from severe brain injuries. There have been significant advances in the field of coma science over the past two decades, providing clinicians with more advanced and precise tools for diagnosing and prognosticating disorders of consciousness (DoC). Advanced neuroimaging and electrophysiological techniques have vastly expanded our understanding of the biological mechanisms underlying consciousness, and have helped identify ...
Source: Presse Medicale - October 7, 2023 Category: General Medicine Authors: Aditya Kumar Mohamed Ridha Jan Claassen Source Type: research
Prognosis of Consciousness Disorders in the Intensive Care Unit
Presse Med. 2023 Oct 5:104180. doi: 10.1016/j.lpm.2023.104180. Online ahead of print.ABSTRACTAssessments of consciousness are a critical part of prognostic algorithms for critically ill patients suffering from severe brain injuries. There have been significant advances in the field of coma science over the past two decades, providing clinicians with more advanced and precise tools for diagnosing and prognosticating disorders of consciousness (DoC). Advanced neuroimaging and electrophysiological techniques have vastly expanded our understanding of the biological mechanisms underlying consciousness, and have helped identify ...
Source: Presse Medicale - October 7, 2023 Category: General Medicine Authors: Aditya Kumar Mohamed Ridha Jan Claassen Source Type: research
Prognosis of Consciousness Disorders in the Intensive Care Unit
Presse Med. 2023 Oct 5:104180. doi: 10.1016/j.lpm.2023.104180. Online ahead of print.ABSTRACTAssessments of consciousness are a critical part of prognostic algorithms for critically ill patients suffering from severe brain injuries. There have been significant advances in the field of coma science over the past two decades, providing clinicians with more advanced and precise tools for diagnosing and prognosticating disorders of consciousness (DoC). Advanced neuroimaging and electrophysiological techniques have vastly expanded our understanding of the biological mechanisms underlying consciousness, and have helped identify ...
Source: Presse Medicale - October 7, 2023 Category: General Medicine Authors: Aditya Kumar Mohamed Ridha Jan Claassen Source Type: research
Severity of kidney involvement as predictor of death, severe heart failure and renal events in patients with type 2 diabetes: data from a prospective cohort
Presse Med. 2023 Oct 4:104177. doi: 10.1016/j.lpm.2023.104177. Online ahead of print.ABSTRACTType 2 diabetes is associated with an increased risk for end-stage renal disease and heart failure, contributing to premature death. All these 3 events are inter-related, suggesting common risk factors and/or pathophysiological pathways. The SURDIAGENE (SUrvie Rénale DIAbète et GENEtique) cohort is a single centre hospital-based cohort of persons living with type 2 diabetes, recruiting participants at Poitiers university hospital, France, from 2002 to 2011 with further follow-up till 2015. Here, we describe the cumulative prevale...
Source: Presse Medicale - October 6, 2023 Category: General Medicine Authors: Samy Hadjadj Pierre Jean Saulnier Bertrand Cariou SURDIAGENE study investigators Source Type: research
Facing the Evidences with Type 2 Diabetes: Contemporary Challenges
Presse Med. 2023 Oct 4:104179. doi: 10.1016/j.lpm.2023.104179. Online ahead of print.NO ABSTRACTPMID:37802242 | DOI:10.1016/j.lpm.2023.104179 (Source: Presse Medicale)
Source: Presse Medicale - October 6, 2023 Category: General Medicine Authors: Michel Marre Source Type: research
Severity of kidney involvement as predictor of death, severe heart failure and renal events in patients with type 2 diabetes: data from a prospective cohort
Presse Med. 2023 Oct 4:104177. doi: 10.1016/j.lpm.2023.104177. Online ahead of print.ABSTRACTType 2 diabetes is associated with an increased risk for end-stage renal disease and heart failure, contributing to premature death. All these 3 events are inter-related, suggesting common risk factors and/or pathophysiological pathways. The SURDIAGENE (SUrvie Rénale DIAbète et GENEtique) cohort is a single centre hospital-based cohort of persons living with type 2 diabetes, recruiting participants at Poitiers university hospital, France, from 2002 to 2011 with further follow-up till 2015. Here, we describe the cumulative prevale...
Source: Presse Medicale - October 6, 2023 Category: General Medicine Authors: Samy Hadjadj Pierre Jean Saulnier Bertrand Cariou SURDIAGENE study investigators Source Type: research
Facing the Evidences with Type 2 Diabetes: Contemporary Challenges
Presse Med. 2023 Oct 4:104179. doi: 10.1016/j.lpm.2023.104179. Online ahead of print.NO ABSTRACTPMID:37802242 | DOI:10.1016/j.lpm.2023.104179 (Source: Presse Medicale)
Source: Presse Medicale - October 6, 2023 Category: General Medicine Authors: Michel Marre Source Type: research
Diagnostic Criteria and Etiopathogenesis of Type 2 Diabetes and Its Complications: Lessons from the Pima Indians
Presse Med. 2023 Sep 30:104176. doi: 10.1016/j.lpm.2023.104176. Online ahead of print.ABSTRACTThe Phoenix Epidemiology and Clinical Research Branch of the National Institute of Diabetes and Digestive and Kidney Diseases has conducted prospective studies of diabetes and its complications in the Pima Indians living in Arizona, USA for over 50 years. In this review we highlight areas in which these studies provided vital insights into the criteria used to diagnose type 2 diabetes, the pathophysiologic changes that accompany the development of type 2 diabetes, and the course and determinants of diabetes complications-focusing ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Helen C Looker Douglas C Chang Leslie J Baier Robert L Hanson Robert G Nelson Source Type: research
Clinical Trials with reno-vascular end points in patients with diabetes: Changing the scenario over the past 20 years
Presse Med. 2023 Sep 30:104178. doi: 10.1016/j.lpm.2023.104178. Online ahead of print.ABSTRACTMajor clinical advances over the last 25 years in the area of diabetic kidney disease (DKD) have been confirmed in large seminal clinical trials. These findings add to the previously identified benefits resulting from intensive glucose and blood pressure control therapies. Furthermore, newer glucose lowering treatments such as SGLT2 inhibitors and GLP-1 agonists appear very promising and are likely to transform the management and outlook of DKD over the next decade. In addition, newer mineralocorticoid receptor antagonists and a r...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Tomasz J Block Mark E Cooper Source Type: research
Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research
Diagnostic Criteria and Etiopathogenesis of Type 2 Diabetes and Its Complications: Lessons from the Pima Indians
Presse Med. 2023 Sep 30:104176. doi: 10.1016/j.lpm.2023.104176. Online ahead of print.ABSTRACTThe Phoenix Epidemiology and Clinical Research Branch of the National Institute of Diabetes and Digestive and Kidney Diseases has conducted prospective studies of diabetes and its complications in the Pima Indians living in Arizona, USA for over 50 years. In this review we highlight areas in which these studies provided vital insights into the criteria used to diagnose type 2 diabetes, the pathophysiologic changes that accompany the development of type 2 diabetes, and the course and determinants of diabetes complications-focusing ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Helen C Looker Douglas C Chang Leslie J Baier Robert L Hanson Robert G Nelson Source Type: research
Clinical Trials with reno-vascular end points in patients with diabetes: Changing the scenario over the past 20 years
Presse Med. 2023 Sep 30:104178. doi: 10.1016/j.lpm.2023.104178. Online ahead of print.ABSTRACTMajor clinical advances over the last 25 years in the area of diabetic kidney disease (DKD) have been confirmed in large seminal clinical trials. These findings add to the previously identified benefits resulting from intensive glucose and blood pressure control therapies. Furthermore, newer glucose lowering treatments such as SGLT2 inhibitors and GLP-1 agonists appear very promising and are likely to transform the management and outlook of DKD over the next decade. In addition, newer mineralocorticoid receptor antagonists and a r...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Tomasz J Block Mark E Cooper Source Type: research
Renal Hemodynamic Changes in patients with Type 2 Diabetes and their clinical impact
Presse Med. 2023 Sep 30:104175. doi: 10.1016/j.lpm.2023.104175. Online ahead of print.ABSTRACTThe dysfunction of the internal mechanics within the kidney's filtering units, known as glomeruli, has been linked to the emergence and progression of diabetic kidney disease (DKD). To better understand this crucial aspect of kidney function and the pathology of DKD, a variety of methods are employed in research, from the introduction of external compounds, such as inulin, iohexol, iothalamate and p-aminohippurate, to cutting-edge imaging techniques and computational analysis. Given the significance of intraglomerular hemodynamic ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Pierre-Jean Saulnier Petter Bjornstad Source Type: research
Diagnostic Criteria and Etiopathogenesis of Type 2 Diabetes and Its Complications: Lessons from the Pima Indians
Presse Med. 2023 Sep 30:104176. doi: 10.1016/j.lpm.2023.104176. Online ahead of print.ABSTRACTThe Phoenix Epidemiology and Clinical Research Branch of the National Institute of Diabetes and Digestive and Kidney Diseases has conducted prospective studies of diabetes and its complications in the Pima Indians living in Arizona, USA for over 50 years. In this review we highlight areas in which these studies provided vital insights into the criteria used to diagnose type 2 diabetes, the pathophysiologic changes that accompany the development of type 2 diabetes, and the course and determinants of diabetes complications-focusing ...
Source: Presse Medicale - October 2, 2023 Category: General Medicine Authors: Helen C Looker Douglas C Chang Leslie J Baier Robert L Hanson Robert G Nelson Source Type: research
