Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health 
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Publication date: July 2019Source: Pregnancy Hypertension, Volume 17Author(s): (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - September 4, 2019 Category: OBGYN Source Type: research
Placenta derived factors involved in the pathogenesis of the liver in the syndrome of haemolysis, elevated liver enzymes and low platelets (HELLP): a review
ConclusionWe assume that these eleven increased placenta derived factors are responsible for LSEC damage which eventually leads to liver failure. This concept shows a possible design of the complicated pathophysiology in HELLP syndrome. However further research is required. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 20, 2019 Category: OBGYN Source Type: research
Postpartum metabolic syndrome after gestational hypertension and preeclampsia, a prospective cohort study
ConclusionAt 6 months postpartum, GH and PE were associated with three-fold or higher risk of MetS and especially hypertension, fasting hypertriglyceridemia, and fasting hyperglycemia. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 19, 2019 Category: OBGYN Source Type: research
Renin-angiotensin system gene variants and risk of early- and late-onset preeclampsia: a single center case-control study
ConclusionWe confirmed the influence of the renin-angiotensin-aldosterone system through these 8 genetic variations on the onset of preeclampsia. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 17, 2019 Category: OBGYN Source Type: research
Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker?
ConclusionsThese results suggest the HtrA1 as early predictive marker of PE and may have a strong clinical relevance in terms of disease prevention. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 17, 2019 Category: OBGYN Source Type: research
Platelet count and mean platelet volume predict atypical pre-eclampsia
ConclusionWe found that the PC, MPV, and PC/MPV may be changed in atypical PE patients who did not have significant PE symptoms. Our results indicated that it could be a diagnostic method to predict atypical PE during pregnancy. PC/MPV and the other platelet parameters can play a role in predicting the development of atypical PE, leading to better diagnosis and management of atypical PE. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 17, 2019 Category: OBGYN Source Type: research
PlGF isoform 3 in maternal serum and placental tissue
ConclusionData obtained indicates that very low amounts of PlGF-3 is present in blood but significantly higher amounts of protein is present in placental tissue where it is prominently associated with cellular membranes. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 10, 2019 Category: OBGYN Source Type: research
The potentially protective role of ATP-binding cassette transporters in preeclampsia via Nrf2
ConclusionsNrf2 protects the placenta against PE by activating the ABC transporter-mediated efflux, indicating a novel target in PE therapy. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 10, 2019 Category: OBGYN Source Type: research
Human Immunodeficiency Virus and risk of Pre-eclampsia and Eclampsia in pregnant women: a meta-analysis on cohort studies
This study is aimed at establishing whether maternal HIV infection is associated with the development of pre-eclampsia (PE) and eclampsia. We comprehensively searched MEDLINE/PubMed, Web of Science, SCOPUS and Embase databases for relevant studies published up to 20 November 2018, without time and language restrictions. We have limited our literature searches to observational studies in humans. We applied a random-effects model to calculate the relative risks (RR) and 95% confidence intervals (CI) for the meta-analyses. We also systematically reviewed eligible studies to determine the effects of HIV infection on imbalance ...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 31, 2019 Category: OBGYN Source Type: research
Understanding and Comparing Practices of Managing Patients with Hypertensive Disorders of Pregnancy in Urban China and the United States
ConclusionsAlthough several clinical characteristics of preeclampsia were similar between hospitals, the rates of cesarean section were higher in China. Provider knowledge was most lacking in areas about diagnostic criteria and medication use for preeclampsia. Future studies are needed to explore these differences. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 25, 2019 Category: OBGYN Source Type: research
Identification and Management of rare causes of chronic hypertension in pregnancy in a tertiary referral centre of North India
Publication date: Available online 18 July 2019Source: Pregnancy HypertensionAuthor(s): Sangeeta Yadav, Neeta Singh, Shruti Jain, Mandakini Pradhan (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 19, 2019 Category: OBGYN Source Type: research
Pregnancy outcomes following home blood pressure monitoring in gestational hypertension
ConclusionsHBPM in women with GH results in significantly less antenatal visits compared to women on a standard pathway of care. The two groups had comparable fetal, neonatal and maternal adverse outcomes. Large multicentre studies are needed to ascertain the safety of rare adverse pregnancy outcomes. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 16, 2019 Category: OBGYN Source Type: research
Aspirin Use during Pregnancy and Hypertensive Disorders in Women with Various Risks
ConclusionAspirin use in pregnancy reduces the risks of maternal hypertensive disorders. Early initiation of aspirin in high-risk women was associated with lower incidence of preeclampsia/eclampsia. Meanwhile, the protective effect of aspirin on term preeclampsia/eclampsia and gestational hypertension may continue till late pregnancy. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 16, 2019 Category: OBGYN Source Type: research
The Prevalence of Regulatory T And Dendritic Cells is Altered in Peripheral Blood of Women with Pre-Eclampsia
ConclusionsA decreased proportion and secretion of related inhibitory cytokines of CD4+CD25+ FOXP3+ Tregs was found in the peripheral blood of pre-eclampsia, while the ratio of mDC/pDC increased. It is speculated that Tregs and DCs may play a role in the decreased immunosuppressive function of pre-eclampsia patients. (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 9, 2019 Category: OBGYN Source Type: research
Relationships between endogenous CYP3A markers and plasma amlodipine exposure and metabolism in early postpartum and non-peripartum women with hypertension
ConclusionsThe early postpartum women had higher plasma 4β-OHC and AML metabolism. The plasma 4β-OHC had positive relationships with amlodipine metabolism in both women groups. AML metabolism and plasma 4β-OHC may be useful as CYP3A markers in early postpartum and non-peripartum women.Graphical abstract (Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health)
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - July 4, 2019 Category: OBGYN Source Type: research
