Cutaneous metastasis of rectal adenocarcinoma: a case report and literature review
Pol J Pathol. 2023;74(3):211-215. doi: 10.5114/pjp.2023.132228.ABSTRACTAccording to the latest data provided by Globocan 2020, the incidence of colorectal cancer ranks third, after lung cancer and breast cancer, becoming a more and more important global health issue. Of the cases diagnosed with colorectal cancer, more than 25% are diagnosed in the metastatic stage, with the presence of secondary tumors more frequently in the liver, lung and bone. Skin metastases from colorectal cancer are still rare today (< 4%). We want to present a rare, unique case in our department of a 74-year-old patient diagnosed 9 years ago with...
Source: Polish Journal of Pathology - November 13, 2023 Category: Pathology Authors: Vesa Alina Octavian Maghiar Laura Maghiar Romina Cuc Ovidiu Pop Andrei Pascalau Monica Boros Adrian Maghiar Source Type: research
Vaginal metastasis of renal clear cell carcinoma: a case report emphasizing the role of immunohistochemistry in differential diagnosis in the absence of a clinical history
We present the case of a 71-year-old patient, with vaginal bleeding, dyspnea, headache, loss of appetite and weakness. Clinical examination revealed a pediculated vaginal mass of 25 mm diameter, of dark-red color and soft spongy consistency, with an ulcerated surface and originating from the anterior wall, which was surgically removed. The morphology was dominanted by large, round to polygonal tumor cells, arranged in a predominantly tubulo-cystic architecture, surrounding numerous blood vessels that dominated the appearance, suggesting a perivascular epithelioid cell tumor (PEComa) or hemangioblastoma but the presence of ...
Source: Polish Journal of Pathology - November 13, 2023 Category: Pathology Authors: Simona Stolnicu Andrei Patrichi Francisc Rozsnyai Robert A Soslow Source Type: research
Primary epithelioid angiosarcoma of endometrium
In this report, we present a case of primary epithelioid angiosarcoma of endometrium to raise awareness and emphasize for pathologists and clinicians.PMID:37955542 | DOI:10.5114/pjp.2023.132302 (Source: Polish Journal of Pathology)
Source: Polish Journal of Pathology - November 13, 2023 Category: Pathology Authors: Selim Sevim Ekin Gedik Hilal Ozakinci Gulsah Kaygusuz Duygu Enneli Source Type: research
Prognostic significance of PD-L1 expression in pancreatic cancer: evidence from an updated meta-analysis
Pol J Pathol. 2023;74(3):151-160. doi: 10.5114/pjp.2023.132220.ABSTRACTRecent studies revealed that programmed cell death ligand 1 (PD-L1) expression was associated with unfavorable prognosis in various solid tumors, but its clinical relevance for pancreatic cancer has not yet been well established. This meta-analysis summarizes the potential prognostic value of PD-L1 in pancreatic cancer. A quantitative meta-analysis was performed by a systematic search of databases including PubMed, EMBASE, Web of Science, Cochrane library, Scopus and Ovid for eligible studies on the prognostic significance of PD-L1 in pancreatic cancer ...
Source: Polish Journal of Pathology - November 13, 2023 Category: Pathology Authors: Chenchen Liu Lijuan Fan Qian Wu Yingjie Shi Xuan Sun Source Type: research
Status of PD-1 and PD-L1 expression in invasive urothelial carcinoma of the bladder with mismatch repair protein deficiency
This study was shown the status of d-MMR and PD-1/PD-L1 in invasive urothelial cancers and their correlation with prognostic markers. PD-1/PD-L1 expression may contribute to the progression and poor prognosis of bladder cancer. However, further studies are required to research the clinical utility.PMID:37955535 | DOI:10.5114/pjp.2023.132221 (Source: Polish Journal of Pathology)
Source: Polish Journal of Pathology - November 13, 2023 Category: Pathology Authors: Nuran Sungu Merve M K ıran Source Type: research
