Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research

Humanized mouse models for inherited thrombocytopenia studies
This article mainly reviews the development of humanized mice models, the construction methods, research status, and problems of using humanized mice for the in vivo study of human thrombopoiesis.PMID:37849076 | DOI:10.1080/09537104.2023.2267676 (Source: Platelets)
Source: Platelets - October 18, 2023 Category: Hematology Authors: Xiaojie Wang Maoshan Chen Lanyue Hu Chengning Tan Xiaoliang Li Peipei Xue Yangzhou Jiang Peipei Bao Teng Yu Fengjie Li Yanni Xiao Qian Ran Zhongjun Li Li Chen Source Type: research

Analysis of clinical characteristics and treatment efficacy in two pediatric cases of < em > ANKRD26 < /em > -related thrombocytopenia
Platelets. 2023 Dec;34(1):2262607. doi: 10.1080/09537104.2023.2262607. Epub 2023 Oct 18.ABSTRACTANKRD26-related thrombocytopenia (ANKRD26-RT or THC2, MIM 188 000), an autosomal dominant thrombocytopenia, is unresponsive to immunosuppressive therapy and susceptible to hematological malignancies. A large number of pediatric patients are diagnosed with immune thrombocytopenia (ITP) every year; however, thrombocytopenia of genetic origin is often missed. Extensive characterization of ANKRD26-RT will help prevent missed diagnosis and misdiagnosis. Furthermore, identification of ANKRD26-RT will help in the formulation of an accu...
Source: Platelets - October 18, 2023 Category: Hematology Authors: Congfei Pang Xiaomei Wu Lauriane Nikuze Hongying Wei Source Type: research