A novel rationale for targeting FXI: Insights from the hemostatic miRNA targetome for emerging anticoagulant strategies
Publication date: Available online 6 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Jamie Nourse, Sven Danckwardt (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 8, 2020 Category: Drugs & Pharmacology Source Type: research

The root cause of drug resistance in HER2-positive breast cancer and the therapeutic approaches to overcoming the resistance
Publication date: Available online 6 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Yuesheng Zhang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 8, 2020 Category: Drugs & Pharmacology Source Type: research

Carcinogenesis: Failure of resolution of inflammation?
Publication date: Available online 3 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Anna Fishbein, Bruce D. Hammock, Charles N. Serhan, Dipak Panigrahy (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 5, 2020 Category: Drugs & Pharmacology Source Type: research

Pharmacological treatment of eating disorders, comorbid mental health problems, malnutrition and physical health consequences
Publication date: Available online 25 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Hubertus Himmerich, Carol Kan, Katie Au, Janet Treasure (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 26, 2020 Category: Drugs & Pharmacology Source Type: research

Tumor organoid models in precision medicine and investigating cancer-stromal interactions
Publication date: Available online 24 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Ren Xu, Xiaotao Zhou, Shike Wang, Christine Trinkle (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 26, 2020 Category: Drugs & Pharmacology Source Type: research

The opioid-P2Y12 inhibitor interaction: Potential strategies to mitigate the interaction and consideration of alternative analgesic agents in myocardial infarction
Publication date: Available online 21 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Himawan Fernando, James A. Shaw, Paul S. Myles, Karlheinz Peter, Dion Stub (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 23, 2020 Category: Drugs & Pharmacology Source Type: research

TGFβ-Directed Therapeutics: 2020
Publication date: Available online 21 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Beverly A. Teicher (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 23, 2020 Category: Drugs & Pharmacology Source Type: research

An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) focusing on clinical and laboratory biomarkers
Publication date: Available online 21 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Junji Yamauchi, Natsumi Araya, Naoko Yagishita, Tomoo Sato, Yoshihisa Yamano (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 23, 2020 Category: Drugs & Pharmacology Source Type: research

NRF2 in human neoplasm: Cancer biology and potential therapeutic target
Publication date: Available online 15 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Yang Liu, Fengchao Lang, Chunzhang Yang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 16, 2020 Category: Drugs & Pharmacology Source Type: research

Updates on community acquired pneumonia management in the ICU
Publication date: Available online 15 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Girish B. Nair, Michael S. Niederman (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 16, 2020 Category: Drugs & Pharmacology Source Type: research

Good cops turn bad: The contribution of neutrophils to immune-checkpoint inhibitor treatment failures in cancer
Publication date: Available online 15 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Huajia Zhang, A. McGarry Houghton (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 16, 2020 Category: Drugs & Pharmacology Source Type: research

Molecular mechanisms and therapeutic implications of tetrandrine and cepharanthine in T cell acute lymphoblastic leukemia and autoimmune diseases
Publication date: Available online 12 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Sachiko Tanaka, Kenji Onda, Kentaro Sugiyama, Haruki Yamada, Toshihiko Hirano (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 13, 2020 Category: Drugs & Pharmacology Source Type: research

G-quadruplex-based aptamers targeting human thrombin: Discovery, chemical modifications and antithrombotic effects
Publication date: Available online 7 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Claudia Riccardi, Ettore Napolitano, Chiara Platella, Domenica Musumeci, Daniela Montesarchio (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 12, 2020 Category: Drugs & Pharmacology Source Type: research

The birth of artemisinin
Publication date: Available online 8 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Nan Ma, Ziyue Zhang, Fulong Liao, Tingliang Jiang, Youyou Tu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 12, 2020 Category: Drugs & Pharmacology Source Type: research

Traditional application and modern pharmacological research of Artemisia annua L.
Publication date: Available online 3 August 2020Source: Pharmacology & TherapeuticsAuthor(s): Xinchi Feng, Shijie Cao, Feng Qiu, Boli Zhang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - August 4, 2020 Category: Drugs & Pharmacology Source Type: research