PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders
Publication date: Available online 9 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Sumit Jamwal, Jennifer Blackburn, John D. Elsworth (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 9, 2020 Category: Drugs & Pharmacology Source Type: research

Targeting the tumor immwpune microenvironment with “nutraceuticals”: From bench to clinical trials
Publication date: Available online 9 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Laura Masuelli, Monica Benvenuto, Chiara Focaccetti, Sara Ciuffa, Sara Fazi, Arianna Bei, Martino Tony Miele, Lucia Piredda, Vittorio Manzari, Andrea Modesti, Roberto Bei (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 9, 2020 Category: Drugs & Pharmacology Source Type: research

Advances in the research on the targets of anti-malaria actions of artemisinin
Publication date: Available online 6 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Jing Yang, Yingke He, Yinbao Li, Xing Zhang, Yin-Kwan Wong, Shengnan Shen, Tianyu Zhong, Jianbin Zhang, Qian Liu, Jigang Wang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 7, 2020 Category: Drugs & Pharmacology Source Type: research

Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID-19-associated cardiovascular complications?
Publication date: Available online 5 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Ahmed M. Darwesh, Wesam Bassiouni, Deanna K. Sosnowski, John M. Seubert (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 6, 2020 Category: Drugs & Pharmacology Source Type: research

The potential of artemisinins as anti-obesity agents via modulating the immune system
Publication date: Available online 3 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Shengnan Shen, Qiwen Liao, Ming Lyu, Yin-Kwan Wong, Xing Zhang, Jing Zhou, Nan Ma, Jigang Wang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 4, 2020 Category: Drugs & Pharmacology Source Type: research

Mineralocorticoid receptor antagonists in patients with chronic kidney disease
Publication date: Available online 4 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Cosimo Cosimato, Thomas Agoritsas, Thomas A. Mavrakanas (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 4, 2020 Category: Drugs & Pharmacology Source Type: research

Targeting peroxisome proliferator-activated receptors: A new strategy for the treatment of cardiac fibrosis
Publication date: Available online 4 October 2020Source: Pharmacology & TherapeuticsAuthor(s): Qirong Lu, Pu Guo, Jingchao Guo, Irma Ares, Bernardo Lopez-Torres, María-Rosa Martínez-Larrañaga, Xu Wang, Arturo Anadón, María-Aránzazu Martínez (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - October 4, 2020 Category: Drugs & Pharmacology Source Type: research

Tubulin modifying enzymes as target for the treatment oftau-related diseases
Publication date: Available online 19 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Krzysztof Rogowski, Khaled Hached, Carole Crozet, Siem van der Laan (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 29, 2020 Category: Drugs & Pharmacology Source Type: research

Natural medicine in neuroprotection for ischemic stroke: Challenges and prospective
Publication date: Available online 28 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Tao Tao, Maozhu Liu, Mengyuan Chen, Ying Luo, Cheng Wang, Tongtong Xu, Yixu Jiang, Yiyan Guo, John H. Zhang (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 29, 2020 Category: Drugs & Pharmacology Source Type: research

Detectives and helpers: Natural products as resources for chemical probes and compound libraries
Publication date: Available online 25 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Anutthaman Parthasarathy, Pavan K. Mantravadi, Karunakaran Kalesh (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 26, 2020 Category: Drugs & Pharmacology Source Type: research

Target identification and validation of natural products with label-free methodology: A critical review from 2005 to 2020
Publication date: Available online 25 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Lingyun Dai, Zhijie Li, Dan Chen, Lin Jia, Jinan Guo, Tianyun Zhao, Pär Nordlund (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 26, 2020 Category: Drugs & Pharmacology Source Type: research

Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms
Publication date: Available online 25 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Mu-Yang Huang, Xiao-Ming Jiang, Bing-Lin Wang, Yang Sun, Jin-Jian Lu (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 26, 2020 Category: Drugs & Pharmacology Source Type: research

Evidence-based strategies for the characterisation of human drug and chemical glucuronidation in vitro and UDP-glucuronosyltransferase reaction phenotyping
Publication date: Available online 25 September 2020Source: Pharmacology & TherapeuticsAuthor(s): John O. Miners, Andrew Rowland, Jonathan J. Novak, Kimberly Lapham, Theunis C. Goosen (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 26, 2020 Category: Drugs & Pharmacology Source Type: research

Nicotine’ actions on energy balance: Friend or foe?
Publication date: Available online 26 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Patricia Seoane-Collazo, Carlos Diéguez, Rubén Nogueiras, Kamal Rahmouni, José Manuel Fernández-Real, Miguel López (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 26, 2020 Category: Drugs & Pharmacology Source Type: research

Interleukin-8: A chemokine at the intersection of cancer plasticity, angiogenesis, and immune suppression
Publication date: Available online 24 September 2020Source: Pharmacology & TherapeuticsAuthor(s): Kristen Fousek, Lucas A. Horn, Claudia Palena (Source: Pharmacology and Therapeutics)
Source: Pharmacology and Therapeutics - September 26, 2020 Category: Drugs & Pharmacology Source Type: research