Development and validation of a nomogram model for predicting distant metastasis of aged ≥50 patients with thyroid carcinoma: a SEER database analysis
CONCLUSIONS: The nomogram model had excellent predictive performance and net benefit for predicting DM of TC patients aged ≥50. The model can help doctors develop treatment plans for their patients.PMID:38567598 | DOI:10.26355/eurrev_202403_35742 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: J-W Yu R Pang B Liu L Zhang L-Y Kong Source Type: research
Causal association between complement system FHR-5, CTRP9, and breast carcinoma in situ: a Mendelian randomization study
CONCLUSIONS: This MR study marks the initial identification of a direct link between FHR-5 and CTRP9 and the susceptibility to breast carcinoma in situ. Delving into the roles of immunomodulatory molecules and immune responses within the tumor microenvironment holds considerable importance for the management of breast carcinoma in situ.PMID:38567599 | DOI:10.26355/eurrev_202403_35743 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: Y-L Peng H Li P Sun H-D Zhang D Li H-B Wang L Zhang Source Type: research
Risk factor analysis and nomogram construction in patients with distant metastatic prostate cancer at different PSA levels: a study based on the SEER database
CONCLUSIONS: We found different independent prognostic factors for different PSA levels in patients with distant metastatic PCa. A new nomogram was constructed to predict OS and CSS in patients, which helps in clinical-assisted decision-making.PMID:38567600 | DOI:10.26355/eurrev_202403_35744 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: H-D Li S-Q Fan F Qin S-T Zhao S-P Kong J-G Ma Source Type: research
Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research
Comparison of urinary incontinence following three different prostate apex disconnection techniques in transurethral thulium laser prostatectomy
CONCLUSIONS: The incidence of urinary incontinence following transurethral thulium laser prostatectomy was lower with semi-separation and pre-separation compared to post-separation.PMID:38567602 | DOI:10.26355/eurrev_202403_35746 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: X-B Meng Y Li Z-H Gao C-J Wang Y-M Gu Source Type: research
Zonulin: can it be used as a marker for preterm labor?
CONCLUSIONS: In conclusion, serum zonulin levels were not useful as a marker for predicting preterm labor. However, examining large-scale studies about the relationship between PROM and zonulin is still needed.PMID:38567603 | DOI:10.26355/eurrev_202403_35747 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: S E Tekg ündüz Source Type: research
Analysis of risk factors affecting the prognosis of patients with sepsis and construction of nomogram prediction model
CONCLUSIONS: Nine clinical variables have been found to be independent risk factors for death in septic patients. The prediction model established based on this has good accuracy, discrimination, and consistency in predicting the prognosis of sepsis patients.PMID:38567604 | DOI:10.26355/eurrev_202403_35748 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: S-H Cui C-Y Liang Y-F Hao Source Type: research
High triglyceride-glucose index is associated with low postoperative satisfaction in patients with posterior instrumented lumbar fusion
CONCLUSIONS: In patients who underwent posterior lumbar instrumentation and fusion surgery, a high preoperative TyG index may predict poor postoperative ODI and PF scores, indicating lower patient satisfaction.PMID:38567605 | DOI:10.26355/eurrev_202403_35750 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: V K ıyak Source Type: research
The CRISPR-Cas9 induced CCR5 Δ32 mutation as a potent gene therapy methodology for resistance to HIV-1 variant: a review
Eur Rev Med Pharmacol Sci. 2024 Mar;28(6):2430-2463. doi: 10.26355/eurrev_202403_35751.ABSTRACTHuman Immunodeficiency Virus (HIV) has continuously been the greatest epidemic for humanity over a period spanning almost five decades. With no specific cure or treatment available to date despite extensive research, the C-C Chemokine Receptor 5, Delta 32 (CCR5 Δ32) allele genetic point mutation plays an imperative role in the prevention of acquired immunodeficiency syndrome (AIDS). This comprehensive study aims to review the induction of the homozygous recessive deletion genotype using the Clustered Regularly Interspaced Short ...
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: M Saifullah O Laghzaoui H Ozyahyalar A Irfan Source Type: research
Association of SOD1 gene variants (50 bp Ins/Del, rs4817415, rs2070424, rs1041740, rs17880135) with plasma protein levels in vitiligo patients and their analysis in silico
CONCLUSIONS: Information regarding the pathogenesis of vitiligo helps recognize risk factors and identify the relationship of diagnostic markers of cell damage inherent to the disease. This will help improve aspects of prevention and the choice of treatment alternatives appropriate to each case.PMID:38567607 | DOI:10.26355/eurrev_202403_35752 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: B C G ómez-Meda G M Z úñiga-González L D Ba ñuelos-Díaz M P Oceguera-Angel A Galindo-G ómez M G S ánchez-Parada A F Garibaldi-R íos B M Torres-Mendoza A L Zamora-Perez J I Delgado-Saucedo M G M árquez-Rosales M P Gallegos-Arreola Source Type: research
Effects of different doses of remimazolam on hemodynamics during general anesthesia in patients with septic shock
CONCLUSIONS: Remimazolam is safe and effective for inducing general anesthesia in patients with septic shock. Low, medium, and high doses of remimazolam can maintain a stable hemodynamic state, and the recovery of hepatic and renal function is certain to depend on the dose.PMID:38567608 | DOI:10.26355/eurrev_202403_35755 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: Q-C Dai J-L Zhao X-Y Miao R Wang Z Hui Source Type: research
Effect of intravenous and topical laryngeal lidocaine on sore throat after extubation: a prospective randomized controlled study
CONCLUSIONS: Both topical laryngeal lidocaine and intravenous lidocaine before intubation have positive effects on preventing sore throat. Topical laryngeal route was superior to intravenous route. Chictr.org.cn ID: ChiCTR2100042442.PMID:38567609 | DOI:10.26355/eurrev_202403_35756 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: J Lin W-D Wang Q-Y Yang Y-L Wen J-H Yang W-Q Fan Y-B Zuo Source Type: research
Dexmedetomidine protects the uterus against ischemia-reperfusion injury in rats
CONCLUSIONS: In our study, it has been documented that dexmedetomidine protects the uterine tissue against ischemia-reperfusion injury.PMID:38567610 | DOI:10.26355/eurrev_202403_35757 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: V K ölükçü M G ürler Balta H Tapar T Karaman S Karaman V Unsal F Gevrek M Katar Source Type: research
Development and validation of a comprehensive model to predict complications after hepatectomy
CONCLUSIONS: We developed an accurate and practical scoring system based on preoperative and early postoperative data to predict poor outcomes after hepatectomy. Further external validation on larger series could lead to the integration of such a tool in the routine clinical practice to support patients' management and early warning during ICU stay.GRAPHICAL ABSTRACT: https://www.europeanreview.org/wp/wp-content/uploads/Graphical-Abstract-NEW-2.pdf.PMID:38567611 | DOI:10.26355/eurrev_202403_35758 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: R Gaspari F Ardito P C Pafundi A W Avolio P Aceto E Adducci M Pallocchi E Parente L Sollazzi M Antonelli F Giuliante Source Type: research
Potential acetylcholinesterase inhibitors to treat Alzheimer's disease
CONCLUSIONS: This study found that Z-9 (Fluoroquinolones) and TBAF-6 (benzimidazole-benzothiazole) compounds improve behavioral and biochemical parameters, thus treating neurodegenerative disorders effectively.PMID:38567612 | DOI:10.26355/eurrev_202403_35759 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 3, 2024 Category: Drugs & Pharmacology Authors: A Saud V Krishnaraju A Taha K Kalpana V Malarkodi S Durgaramani V Vinoth Prabhu F A Saleh S Ezhilarasan Source Type: research
