Retraction Note: Dual Blockade of PD-1 and LAG3 Immune Checkpoints Increases Dendritic Cell Vaccine Mediated T Cell Responses in Breast Cancer Model
(Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 26, 2023 Category: Drugs & Pharmacology Source Type: research
Impact of Formulation and Microneedle Length on Transdermal Metronidazole Permeation through Microneedle-Treated Skin
ConclusionsFormulation and microneedle conditions both impacted metronidazole permeation. These data will be used to estimatein vivo serum concentrations after applying metronidazole to microneedle-treated skin in humans. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 22, 2023 Category: Drugs & Pharmacology Source Type: research
2022 and 2023 Reviewer Thanks
(Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 20, 2023 Category: Drugs & Pharmacology Source Type: research
Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing
ConclusionThe results of this study showed the usefulness of the in-line probes to automate continuous assessment of AlPO4 batch-to-batch consistency during in-house adjuvant production at the industrial scale.Graphical Abstract (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 19, 2023 Category: Drugs & Pharmacology Source Type: research
Exploiting Apical Sodium-Dependent Bile Acid Transporter (ASBT)-Mediated Endocytosis with Multi-Functional Deoxycholic Acid Grafted Alginate Amide Nanoparticles as an Oral Insulin Delivery System
ConclusionsGiven the significance of administering insulin through oral route, deoxycholic acid-modified alginate nanoparticles present a viable option to surmount various obstacles presented by the gastrointestinal. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 19, 2023 Category: Drugs & Pharmacology Source Type: research
Application of PAT Probes in Aluminum Phosphate Adjuvant Manufacturing
ConclusionThe results of this study showed the usefulness of the in-line probes to automate continuous assessment of AlPO4 batch-to-batch consistency during in-house adjuvant production at the industrial scale.Graphical Abstract (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 19, 2023 Category: Drugs & Pharmacology Source Type: research
Exploiting Apical Sodium-Dependent Bile Acid Transporter (ASBT)-Mediated Endocytosis with Multi-Functional Deoxycholic Acid Grafted Alginate Amide Nanoparticles as an Oral Insulin Delivery System
ConclusionsGiven the significance of administering insulin through oral route, deoxycholic acid-modified alginate nanoparticles present a viable option to surmount various obstacles presented by the gastrointestinal. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 19, 2023 Category: Drugs & Pharmacology Source Type: research
Integrated Exposure –Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis
ConclusionsThe collectively tested covariates explain some of the variability in dupilumab response in patients with AD. Patients in all age groups showed adequate response to dupilumab; however, children showed slightly higher drug effects compared to adults and adolescents at equivalent concentrations. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 11, 2023 Category: Drugs & Pharmacology Source Type: research
PBPK/PD Modeling of Nifedipine for Precision Medicine in Pregnant Women: Enhancing Clinical Decision-Making for Optimal Drug Therapy
ConclusionBased on available literature data, the PBPK/PD model of Nifedipine in pregnancy demonstrated good predictive performance. It will help optimize individualized dosing of Nifedipine, improve treatment outcomes, and minimize the risk of adverse reactions in mothers and infants. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 4, 2023 Category: Drugs & Pharmacology Source Type: research
Editorial: Improving Product Quality through Process and Materials Understanding
(Source: Pharmaceutical Research)
Source: Pharmaceutical Research - December 1, 2023 Category: Drugs & Pharmacology Source Type: research
