Nephrotic Syndrome
Nephrotic syndrome (NS) encompasses a variety of disease processes leading to heavy proteinuria and edema. Minimal change disease (MCD) remains the most common primary cause of NS, as well as the most responsive to pharmacologic treatment with often minimal to no chronic kidney disease. Other causes of NS include focal segmental glomerulosclerosis, which follows MCD, and secondary causes, including extrarenal or systemic diseases, infections, and drugs. Although initial diagnosis relies on clinical findings as well as urine and blood chemistries, renal biopsy and genetic testing are important diagnostic tools, especially w...
Source: Pediatrics in Review - January 28, 2022 Category: Pediatrics Source Type: research
Reticulated Rash on the Bilateral Lower Extremities in an 11-year-old Girl
(Source: Pediatrics in Review)
Source: Pediatrics in Review - January 28, 2022 Category: Pediatrics Source Type: research
Thank You
We are still in a pandemic, largely following the same pattern of events described for the first wave, second wave, and third wave of the H1N1 influenza A virus, also known as the Spanish flu, that swept the world from 1918 through 1920. If history repeats itself, and it usually does, we only have six months to a year more to endure. Hang in there. (Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Knee Trauma
Over each of the 1st 4 months of the year, PIR will feature a mini-series of In Briefs dealing with injuries to the extremities of children: knee, ankle, elbow, and hand. Read and enjoy!–Henry M. Adam, In Brief Associate Editor (Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Hypothermia and Cold Injury in Children
Accidental hypothermia is common and carries significant risk of morbidity and mortality. Hypothermia, defined when the body temperature falls below 95 °F (<35 °C), occurs when the body loses more heat than it can absorb or generate. It is classified as mild, moderate, severe, or profound (Table). Environmental cold exposure, near drowning, and immersion are common causes, as are trauma and intoxication. Hypothermia is not always easily diagnosed, so awareness of the presentation, associated risks, and treatment is needed. Localized cold injury, of which frostbite is the most commonly reported, is often seen with hypo...
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Care of the Immigrant Child
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Human Immunodeficiency Virus Preexposure Prophylaxis in Adolescents and Young Adults
Human immunodeficiency virus (HIV) prevention holds the promise of decreasing the burden of HIV infections worldwide. Access to HIV prevention services, including preexposure prophylaxis (PrEP), is a key strategy in reducing HIV transmission, but it continues to be underused. PrEP, a once-daily medication for HIV prevention, is approved for adolescents. A pediatrician ’s role is critical in identifying and increasing access for adolescents and young adults to PrEP services and reducing HIV acquisition in youth. (Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Feeding Intolerance in a 3-month-old
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Migratory Arthralgia in a 3-year-old Girl
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Central Nervous System Tumors in Children
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Chest Mass in a Newborn Infant
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Rash in a 2-month-old Premature Infant
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Hives and Fever in a 13-year-old Boy
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 17, 2021 Category: Pediatrics Source Type: research
Fever and Abdominal Pain in a 10-year-old with Autism
(Source: Pediatrics in Review)
Source: Pediatrics in Review - December 1, 2021 Category: Pediatrics Source Type: research
Yersinia Enterocolitica
Yersinia enterocolitica, a gram-negative coccobacillus, is a zoonotic infection in wild and domestic animals, which, when transmitted to humans, can cause yersiniosis. Acute yersiniosis commonly presents in children and adolescents as acute, self-limiting bloody diarrhea that can last 1 to 3 weeks. Children younger than 5 years are at higher risk for contracting the disease and developing complications such as mesenteric lymphadenitis and extraintestinal infections. (Source: Pediatrics in Review)
Source: Pediatrics in Review - December 1, 2021 Category: Pediatrics Source Type: research
