Grieving lost selves: Throop's concept of presencing forth of an absence
This article expands on C.J. Throop's concept of "presencing forth of an absence" introduced in his 2010 article "Latitudes of loss: on the vicissitudes of empathy," applying it to elucidate personal stories of grief, including an experience of the ambiguous loss of a child. The author provides a novel framework for the intersubjective experience of the grieving person. The author offers pediatric healthcare providers fresh insight into the experience of patient families.PMID:38443524 | DOI:10.1038/s41390-024-03119-1 (Source: Pediatric Research)
Source: Pediatric Research - March 5, 2024 Category: Pediatrics Authors: Kathy A Riley Source Type: research
Increased mortality in infants with abnormal T-cell receptor excision circles
CONCLUSION: Infants with abnormal TREC-NBS may be at a higher risk of morbidity and mortality and should be carefully followed, especially if discharged home before a repeat screen can be completed.IMPACT: This study explores the risk factors and mortality for newborns with secondary T-cell lymphopenia captured on T-Cell Receptor Excision Circles based newborn screening (TREC-NBS). Abnormal TREC-NBS allows for prompt life-saving interventions for primary immunological conditions such as Severe Combined Immunodeficiency (SCID), but can also be associated with non-immunologic conditions. Unresolved and late abnormal TREC-NBS...
Source: Pediatric Research - March 5, 2024 Category: Pediatrics Authors: Jenny Huang Ashwin Shankar Isabel Hurden Ronald Thomas Joseph Hill Divya Seth Elizabeth Secord Pavadee Poowuttikul Source Type: research
Temperature probe placement in very preterm infants during delivery room stabilization: an open-label randomized trial
CONCLUSIONS: In very preterm infants, upper back site was equally effective as the axilla in maintaining normothermia, with no increase in adverse events.CLINICAL TRIAL REGISTRATION: The study was registered with the Australian New Zealand Clinical Trials Registry (ACTRN12620000293965).IMPACT: Substantial variation in practice exists for the site of securing a temperature probe during delivery room stabilization of very preterm infants and the influence of temperature probe site on thermoregulation remains unknown. In this study, upper back site was equally effective as the axilla in maintaining normothermia, with no incre...
Source: Pediatric Research - March 5, 2024 Category: Pediatrics Authors: Pranav R Jani Rajesh Maheshwari Hannah Skelton Patricia Viola Sheela Thomas Lynette Ryder Mihaela Culcer Umesh Mishra Swapnil Shah Jane Baird James Elhindi Ann-Maree Padernia Traci-Anne Goyen Daphne D'Cruz Melissa Luig Dharmesh Shah Source Type: research
Perinatal risk factors associated with acute kidney injury severity and duration among infants born extremely preterm
CONCLUSION: We identified major risk factors for severe AKI that can be the focus of future research.IMPACT STATEMENT: Time-dependent risk factors for severe acute kidney injury (AKI) and its duration are not well defined among infants born <28 weeks' gestation. Over 1 in 5 infants born <28 weeks' gestation experienced severe AKI, and this study identified several major time-dependent perinatal risk factors occurring within 72 h prior to severe AKI. This study can support efforts to develop risk stratification and clinical decision support to help mitigate modifiable risk factors to reduce severe AKI occurrence and d...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Keia Sanderson Russell Griffin Nekayla Anderson Andrew M South Jonathan R Swanson Michael Zappitelli Heidi J Steflik Marissa J DeFreitas Jennifer Charlton David Askenazi Neonatal Kidney Collaborative (NKC) Research Committee Source Type: research
Effects of hemodynamic alterations and oxygen saturation on cerebral perfusion in congenital heart disease
CONCLUSION: We detected regional differences in compensation to the cerebral steal effect in patients with severe CHD.IMPACT: Patients with severe congenital heart disease (CHD) have altered postnatal brain hemodynamics. A systemic-to-pulmonary shunt was associated with decreased perfusion in cortical gray matter but preserved perfusion in deep gray matter, pointing towards regional differences in compensation to the cerebral steal effect. No effects of aortic arch obstruction and arterial oxygenation on cerebral perfusion were seen. Cerebral perfusion was increased in patients with CHD compared to healthy controls after a...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Alexandra De Silvestro Giancarlo Natalucci Maria Feldmann Cornelia Hagmann Thi Dao Nguyen Seline Coraj Andras Jakab Raimund Kottke Beatrice Latal Walter Knirsch Ruth Tuura Source Type: research
Maternal milk in the NICU: An everyday intervention to improve brain development
Pediatr Res. 2024 Mar 4. doi: 10.1038/s41390-024-03125-3. Online ahead of print.NO ABSTRACTPMID:38438552 | DOI:10.1038/s41390-024-03125-3 (Source: Pediatric Research)
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Stephanie L Merhar Steven P Miller Source Type: research
Less common phenotypes of myelin oligodendrocyte glycoprotein antibody-related diseases in children deserve more attention
CONCLUSION: 40/236 (16.9%) of children with MOGAD had less common phenotypes. Less common clinical phenotypes of pediatric MOGAD are susceptible to misdiagnosis and deserve more attention.IMPACT: This is the first comprehensive analysis and summary of all less commonl clinical phenotypes of MOGAD in children, while previous studies have only focused on a specific phenotype or case reports. We analyzed the characteristics of MOGAD in children and further revealed the reasons why these less common clinical phenotypes are prone to misdiagnosis and deserve more attention. Our research on treatment has shown that early detectio...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Xiao-Yu Wang Yan Jiang Peng Wu Jian-Nan Ma Ping Yuan Xiu-Juan Li Li Jiang Source Type: research
Understanding the multidimensional neurodevelopmental outcomes in children after congenital Zika virus exposure
We present a multidimensional framework to understand child neurodevelopment from an interdisciplinary and whole-child perspective (International Classification of Functioning, Disability and Health model) and multi-domain ZIKV Outcome Toolboxes. The toolboxes are for clinicians, researchers, child educators, and others to implement longitudinal multi-domain neurodevelopmental assessments between ages 0-12 years. Recent innovations in telehealth and neuroimaging can help evaluate outcomes in ZIKV exposed children. The objective is to describe the multiple facets of neurodevelopmental focused care that can support the healt...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Sarah B Mulkey Meagan E Williams Colleen Peyton Margarita Arroyave-Wessel Madison M Berl Carlos Cure Michael E Msall Source Type: research
Science and policy in the Third Reich: a commentary on history and current relevance
Pediatr Res. 2024 Mar 4. doi: 10.1038/s41390-024-03123-5. Online ahead of print.NO ABSTRACTPMID:38438555 | DOI:10.1038/s41390-024-03123-5 (Source: Pediatric Research)
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Michael Shevell Source Type: research
Trauma and warfare and clinicians' role
Pediatr Res. 2024 Mar 4. doi: 10.1038/s41390-024-03124-4. Online ahead of print.NO ABSTRACTPMID:38438556 | DOI:10.1038/s41390-024-03124-4 (Source: Pediatric Research)
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Fiona McNicholas Aoife Twohig Source Type: research
Perinatal risk factors associated with acute kidney injury severity and duration among infants born extremely preterm
CONCLUSION: We identified major risk factors for severe AKI that can be the focus of future research.IMPACT STATEMENT: Time-dependent risk factors for severe acute kidney injury (AKI) and its duration are not well defined among infants born <28 weeks' gestation. Over 1 in 5 infants born <28 weeks' gestation experienced severe AKI, and this study identified several major time-dependent perinatal risk factors occurring within 72 h prior to severe AKI. This study can support efforts to develop risk stratification and clinical decision support to help mitigate modifiable risk factors to reduce severe AKI occurrence and d...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Keia Sanderson Russell Griffin Nekayla Anderson Andrew M South Jonathan R Swanson Michael Zappitelli Heidi J Steflik Marissa J DeFreitas Jennifer Charlton David Askenazi Neonatal Kidney Collaborative (NKC) Research Committee Source Type: research
Effects of hemodynamic alterations and oxygen saturation on cerebral perfusion in congenital heart disease
CONCLUSION: We detected regional differences in compensation to the cerebral steal effect in patients with severe CHD.IMPACT: Patients with severe congenital heart disease (CHD) have altered postnatal brain hemodynamics. A systemic-to-pulmonary shunt was associated with decreased perfusion in cortical gray matter but preserved perfusion in deep gray matter, pointing towards regional differences in compensation to the cerebral steal effect. No effects of aortic arch obstruction and arterial oxygenation on cerebral perfusion were seen. Cerebral perfusion was increased in patients with CHD compared to healthy controls after a...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Alexandra De Silvestro Giancarlo Natalucci Maria Feldmann Cornelia Hagmann Thi Dao Nguyen Seline Coraj Andras Jakab Raimund Kottke Beatrice Latal Walter Knirsch Ruth Tuura Source Type: research
Maternal milk in the NICU: An everyday intervention to improve brain development
Pediatr Res. 2024 Mar 4. doi: 10.1038/s41390-024-03125-3. Online ahead of print.NO ABSTRACTPMID:38438552 | DOI:10.1038/s41390-024-03125-3 (Source: Pediatric Research)
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Stephanie L Merhar Steven P Miller Source Type: research
Less common phenotypes of myelin oligodendrocyte glycoprotein antibody-related diseases in children deserve more attention
CONCLUSION: 40/236 (16.9%) of children with MOGAD had less common phenotypes. Less common clinical phenotypes of pediatric MOGAD are susceptible to misdiagnosis and deserve more attention.IMPACT: This is the first comprehensive analysis and summary of all less commonl clinical phenotypes of MOGAD in children, while previous studies have only focused on a specific phenotype or case reports. We analyzed the characteristics of MOGAD in children and further revealed the reasons why these less common clinical phenotypes are prone to misdiagnosis and deserve more attention. Our research on treatment has shown that early detectio...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Xiao-Yu Wang Yan Jiang Peng Wu Jian-Nan Ma Ping Yuan Xiu-Juan Li Li Jiang Source Type: research
Understanding the multidimensional neurodevelopmental outcomes in children after congenital Zika virus exposure
We present a multidimensional framework to understand child neurodevelopment from an interdisciplinary and whole-child perspective (International Classification of Functioning, Disability and Health model) and multi-domain ZIKV Outcome Toolboxes. The toolboxes are for clinicians, researchers, child educators, and others to implement longitudinal multi-domain neurodevelopmental assessments between ages 0-12 years. Recent innovations in telehealth and neuroimaging can help evaluate outcomes in ZIKV exposed children. The objective is to describe the multiple facets of neurodevelopmental focused care that can support the healt...
Source: Pediatric Research - March 4, 2024 Category: Pediatrics Authors: Sarah B Mulkey Meagan E Williams Colleen Peyton Margarita Arroyave-Wessel Madison M Berl Carlos Cure Michael E Msall Source Type: research
