Sex Differences in Comorbidities of Pediatric Craniosynostosis at Presentation
This study seeks to explore potential sexual dimorphisms in craniosynostosis patients at the time of presentation. Methods: We conducted a retrospective, cross-sectional review of male and female non-syndromic craniosynostosis (NSC) patients between the ages of 1 month and 9 years that were evaluated at a 500-bed academic hospital or a 977-bed private hospital in Lubbock, Texas, United States. Common comorbidities including ophthalmologic diagnoses, developmental delays, obstructive sleep apnea, chronic otitis media, hearing loss, chronic headaches, and seizure disorders were evaluated. The NSC cohort was compared to a si...
Source: Pediatric Neurosurgery - December 21, 2022 Category: Neurosurgery Source Type: research

Considerations for choice of cranioplasty material for pediatric patients
Conclusion: Autologous and alloplastic cranioplasty materials both have good outcomes with low rates of revision surgery in the pediatric population. Alloplastic implants may be considered in the setting of infection as reason for craniectomy given the lower rate of revision surgery and need for removal. Patients with craniosynostosis as reason for cranioplasty have a higher risk of requiring revision or additional surgeries, regardless of implant used. (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - December 7, 2022 Category: Neurosurgery Source Type: research

Images in Pediatric Neurosurgery: Occult Intraosseous Dermoid Cyst at the Nasofrontal Junction
Pediatr Neurosurg (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - November 30, 2022 Category: Neurosurgery Source Type: research

Images in Pediatric Neurosurgery: Occult Intraosseous Dermoid Cyst at the Nasofrontal Junction
(Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - November 30, 2022 Category: Neurosurgery Source Type: research

Occult Intraosseous Dermoid Cyst at the Nasofrontal Junction
Conclusion: This case, despite an exploration under the nasal bones, initially received incomplete resection and experienced multiple infections because of failure to appreciate the portion hidden in the nasal bones. Our case was successfully treated with ostectomy of nasal bones without recurrence and complications. This procedure allows unobstructed visualization of the entire cyst leading to the complete removal of the lesion. This is an instructive case to show that portions of the cyst may remain hidden and lead to recurrent infection, and complete resection with sufficient exposure of the entire lesion is needed to s...
Source: Pediatric Neurosurgery - November 30, 2022 Category: Neurosurgery Source Type: research

Left Ophthalmic Segment Internal Carotid Artery Aneurysm Treated with Flow Diversion in a Child with Apert Syndrome: Technical Note
Conclusion: Post-procedurally, over the next year, the patient developed word-finding difficulty and stuttering speech. He was found to have in-stent ICA stenosis and middle cerebral artery (MCA) stenosis at the first follow-up and underwent an initial angioplasty. After several weeks, ICA, MCA, and anterior cerebral artery stenoses were identified, and the patient underwent angioplasties for the ICA and MCA stenoses. On follow-up examination after the second procedure, the patient had tremendous improvement in his speech difficulties and was doing well clinically.Pediatr Neurosurg (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - October 28, 2022 Category: Neurosurgery Source Type: research

Left ophthalmic segment internal carotid artery aneurysm treated with flow diversion in a child with Apert syndrome: technical note
Conclusion: Postprocedurally, over the next year, the patient developed word-finding difficulty and stuttering speech. He was found to have in-stent ICA stenosis and middle cerebral artery (MCA) stenosis at the first follow up and underwent an initial angioplasty. After several weeks, ICA, MCA, and anterior cerebral artery stenoses were identified and the patient underwent angioplasties for the ICA and MCA stenoses. On follow-up examination after the second procedure, the patient had tremendous improvement in his speech difficulties and was doing well clinically. (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - October 28, 2022 Category: Neurosurgery Source Type: research

Detection and Management of Tethered Cord in Anorectal Malformation: A Survey of Pediatric Neurosurgeons in the United States
Conclusions: A wide variety of diagnostic criteria and indication for procedural intervention exists for management of tethered cord patients with and wit hout ARM. Further studies are needed to determine outcomes. Prospective protocols need to be developed and evaluated to standardize care for this patient population and determine best practices. (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - October 18, 2022 Category: Neurosurgery Source Type: research

MicroRNA-138 regulates spinal cord development by activating the Shh in fetal rats
Conclusion: These findings indicated that miRNA-138 overexpression could protect the spinal cord development of fetal rats, and the underlying mechanisms were associated with Shh expression. The present study provides a novel strategy to promote the molecular mechanism of embryonic spinal cord development. (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - October 17, 2022 Category: Neurosurgery Source Type: research

Cranial Irradiation for Childhood Cancers and Adult Risk of Meningioma
Following cranial irradiation, there is an increased risk of developing secondary neoplasms, especially meningiomas. Despite childhood cancer survivors who have undergone cranial irradiation having an increased risk of acquiring radiation-induced meningioma (RIM), there is no widely used, standard guideline for meningioma screening. At a single institution, we reviewed three adult survivors of childhood cancer who were treated for RIM between 2010 and 2020. We recorded age at diagnosis for the primary lesion, the radiation dose, age at RIM diagnosis, and tumor characteristics, including treatment, pathology, and outcome. T...
Source: Pediatric Neurosurgery - October 17, 2022 Category: Neurosurgery Source Type: research

Calcified epidural hematoma after conservative treatment of acute epidural hematoma in the pediatric population: A systematic review.
Conclusions: Surgery was the most commonly used treatment for OEH. Data for conservative treatment of OEH are limited. Magnetic resonance imaging or ultrasound within the first 2 months, to check for EDH resolution, may be crucial to rule out complications in pediatric patients. (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - September 27, 2022 Category: Neurosurgery Source Type: research

Permanent Visual Impairment due to Delayed Diagnosis of Shunt Malfunction in Case of Lack of Typical Features of Increased Intracranial Pressure and Unchanged Ventricular Size
Conclusion: Visual impairment as the primary manifestation of V-P shunt malfunction was uncommon and could be easily missed or misdiagnosed as the only problem for lack of typical features of increased intracranial pressure (ICP) and unchanged ventricular size. Earlier definitive diagnosis and surgical intervention could prevent a further development of the visual loss caused by V-P shunt malfunction. (Source: Pediatric Neurosurgery)
Source: Pediatric Neurosurgery - August 31, 2022 Category: Neurosurgery Source Type: research