Isolated intracranial hypertension as a presentation of pediatric Lyme borreliosis: a case report and literature review
It is extremely rare for Lyme borreliosis to present solely with features of increased intracranial pressure. The treatment of pediatric Lyme neuroborreliosis with oral versus intravenous antibiotics remains controversial. (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 2, 2024 Category: Neurology Authors: Jeffrey M. Mah, Cody Lo, Michael D. O ’Connor Tags: Research Paper Source Type: research

A Retrospective, Cross-Sectional Analysis of Motor Development, Cognition, and Mood in 87 Patients With Childhood-Onset Hereditary Spastic Paraplegias
HSP is a heterogeneous group of rare genetic diseases. In childhood, little is known of the development and psychological manifestations. (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Brooke M. Marvel, Linsley Smith, Jonathan J. Rios, Michelle R. Christie Tags: Research Paper Source Type: research

Accelerated Course of Cerebral Adrenoleukodystrophy After Coronavirus Disease 2019 Infection
Coronavirus disease 2019 (COVID-19) can not only infect the respiratory system but also affect the nervous system through the release of inflammatory factors. Our study aimed to investigate the effect of COVID-19 infection on cerebral adrenoleukodystrophy (ALD). (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Qiu-Hong Wang, Jing Wang, Yang-Yang Wang, Wen He, Chen Feng, Jing Gao, Qian Lu, Yi Wang, Shuo Dun, Qi Zhang, Li-Ping Zou Tags: Research Paper Source Type: research

Frequency of Cerebellar Abnormalities Associated With the Differing Magnetic Resonance Imaging Patterns of Term Hypoxic-Ischemic Injury in Children
We aimed to determine the frequency of cerebellar injury using delayed magnetic resonance imaging (MRI) in children with cerebral palsy, diagnosed with term hypoxic-ischemic injury (HII), and to characterize this for the different MRI patterns of HII. (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Shyam Sunder B. Venkatakrishna, Parth Sharma, Luis Octavio Tierradentro-Garcia, Mohamed Elsingergy, Fikadu Worede, Jelena Curic, Cesar Augusto P. Alves, Savvas Andronikou Tags: Research Paper Source Type: research

A Retrospective, Cross-Sectional Analysis of Motor Development, Cognition and Mood in 87 Patients with Childhood Onset Hereditary Spastic Paraplegias
Retrospective review of development, cognition, and mood in childhood onset hereditary spastic paraplegias (HSP). (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Brooke M. Marvel, Linsley Smith, Jonathan J. Rios, Michelle R. Christie Tags: Research Paper Source Type: research

Accelerated course of cerebral adrenoleukodystrophy after COVID-19 infection
The objective of this study was to investigate the effect of COVID-19 infection on cerebral adrenoleukodystrophy (ALD). (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Qiu-Hong Wang, Jing Wang, Yang-Yang Wang, Wen He, Chen Feng, Jing Gao, Qian Lu, Yi Wang, Shuo Dun, Qi Zhang, Li-Ping Zou Tags: Research Paper Source Type: research

Three-dimensional upper limb movement analysis in children and adolescents with brachial plexus birth injury: A Systematic Review
To synthesize the current evidence on clinical use of 3D upper limb movement analysis (3D-ULMA) in children and adolescents with brachial plexus birth injury (BPBI). (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Laura LE ROY, Anke VAN BLADEL, Sophie DE MITS, Luc Vanden Bossche, Ruth VAN DER LOOVEN Tags: Review Article Source Type: research

Frequency of Cerebellar Abnormalities Associated with the Differing MRI Patterns of Term Hypoxic ischemic injury (HII) in Children
We aimed to determine the frequency of cerebellar injury using delayed MRI in children with cerebral palsy, diagnosed with term HII (Hypoxic ischemic injury), and to characterize the cerebellar abnormalities on MRI for each of the different MRI patterns of HII. (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Shyam Sunder B Venkatakrishna, Parth Sharma, Luis Octavio Tierradentro-Garcia, Mohamed Elsingergy, Fikadu Worede, Jelena Curic, Cesar Augusto P Alves, Savvas Andronikou Tags: Research Paper Source Type: research

Acute flaccid paralysis, seizures, and encephalopathy in a pediatric patient with influenza A and COVID-19 infection
We report a case of AFP and encephalopathy in a 4-year-old female with a history of hypothyroidism (on levothyroxine; previously healthy otherwise), associated with acute influenza A and recent COVID-19 co-infection. Patient presented with new onset focal motor seizures with impaired awareness 6 days into a febrile upper respiratory illness in November 2022. On presentation, her vital signs were within normal limits. She had recently recovered from COVID-19 infection in the preceding 3 weeks (of note, this was her second COVID infection; initial infection was in January 2022). (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Natalie Sloof, Christopher Donald Hue, Craig Campbell, Michelle A. Barton, Maryam Nabavi Nouri Tags: Research Paper Source Type: research

The Papilledema Dilemma: Myopic Pseudopapilledema from Peripapillary Hyper-reflective Ovoid Mass-like Structures (PHOMS)
A 11-year-old Chinese boy with early onset of myopia was evaluated for intracranial hypertension, in a context of headache and suspected bilateral papilledema (Figure A). His neurological examination was unremarkable. Optical coherence tomography (OCT) of the optic discs (Figure B) ruled out optic disc drusen (ODD), but confirmed isolated bilateral peripapillary hyper-reflective ovoid mass-like structures (PHOMS), with no signs of papilledema. Brain MRI with contrast was normal. (Source: Pediatric Neurology)
Source: Pediatric Neurology - January 1, 2024 Category: Neurology Authors: Bryan Sim, Dan Milea Tags: Short Communication Source Type: research

Association between assisted reproductive technology and cerebral palsy: a meta-analysis
Since 1978 many children are born thanks to assisted reproductive technology (ART). However, the long-term effects of these therapies are still not fully known. (Source: Pediatric Neurology)
Source: Pediatric Neurology - December 29, 2023 Category: Neurology Authors: Amaia Cavero-Ibiricu, Javier Canelas-Fern ández, Inés Gómez-Acebo, Jessica Alonso-Molero, Daniel Martínez-Jiménez, Javier Llorca, María J. Cabero-Perez, Trinidad Dierssen-Sotos Tags: Review Article Source Type: research

Targeted Needs Assessment for a National Neurogenetics Curriculum
We need to prepare child neurology trainees to enter a rapidly evolving field with the explosion of diagnostic and therapeutic options in neurogenetics. To better understand gaps in current child neurology training, Sen et al. conducted a national survey of US child neurology trainees and found knowledge gaps related to ordering and interpreting genetic testing, managing metabolic emergencies, and referring patients to clinical trials.1 Using this quantitative data as a general needs assessment, our team then proceeded in the next phase of developing a national neurogenetics curriculum using Kern ’s six-step approach2: c...
Source: Pediatric Neurology - December 28, 2023 Category: Neurology Authors: Rachel Gottlieb-Smith, Kuntal Sen, Louis T. Dang, Jeffrey A. Strelzik Source Type: research

Encephalitis is an Important Phenotype of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Diseases: A Single-Center Cohort Study
To evaluate the clinical phenotypes, treatment responses, and outcomes of children with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). (Source: Pediatric Neurology)
Source: Pediatric Neurology - December 27, 2023 Category: Neurology Authors: Changhong Ren, Anna Zhou, Ji Zhou, Xiuwei Zhuo, Lifang Dai, Xiaojuan Tian, Xinying Yang, Shuai Gong, Changhong Ding, Fang Fang, Xiaotun Ren, Weihua Zhang Tags: Research Paper Source Type: research

A Potential Mechanism of Neurological Impairment in Children With Infantile Spasm: Based on Microanatomic Structure Analysis Employing Voxel-Based Morphometry and Surface-Based Morphometry
Infantile epileptic spasms syndrome (IESS) would accompany with severe neurological impairment. Our study aimed to explore the potential mechanism by employing voxel-based and surface-based morphometry to detect brain microwould accompany with severe neurological impairment. Our study aimed to explore the potential mechanism by employing voxel-based and surface-based morphometry to detect brain microanatomic structure alteration. (Source: Pediatric Neurology)
Source: Pediatric Neurology - December 22, 2023 Category: Neurology Authors: Xiaoyu Wang, Yuchun Huang, Li Chen, Jiahui Mai, Diangang Fang, Tong Mo, Xinxin Qi, Hongwu Zeng Tags: Research Paper Source Type: research

A potential mechanism of neurological impairment in children with infantile spasm: based on micro-anatomic structure analysis employing voxel-based morphometry and surface-based morphometry
The objective was to explore the potential mechanism of neurological impairment in children with IESS by using diffeomorphic anatomical registration through exponential lie algebra (DARTEL). (Source: Pediatric Neurology)
Source: Pediatric Neurology - December 22, 2023 Category: Neurology Authors: Xiaoyu Wang, Yuchun Huang, Li Chen, Jiahui Mai, Diangang Fang, Tong Mo, Qi Xinxin, Hongwu Zeng Tags: Research Paper Source Type: research