Relationship Between Postural Asymmetry, Balance, and Pain in Children With Spastic Cerebral Palsy
Primary symptoms of cerebral palsy (CP), such as spasm and weakness, can lead to secondary musculoskeletal problems. Exploring the interplay and impact of secondary symptoms is essential in CP management. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 22, 2024 Category: Neurology Authors: Zahra Shekari, Razieh Sadeghian Afarani, Saeid Fatorehchy, Enayatollah Bakhshi, Soheila Shahshahani, Elahe Mousavi Tags: Research Paper Source Type: research
De Novo Brain Vascular Malformations in Hereditary Hemorrhagic Telangiectasia
Approximately 10% of people with hereditary hemorrhagic telangiectasia (HHT) have brain vascular malformations (VMs). Few reports describe de novo brain VM formation or VM growth. International HHT Guidelines recommend initial brain VM screening upon HHT diagnosis in children but do not address rescreening. We aimed to confirm whether brain VMs can form de novo in patients with HHT. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 21, 2024 Category: Neurology Authors: Lauren A. Beslow, Timo Krings, Helen Kim, Steven W. Hetts, Michael T. Lawton, Felix Ratjen, Kevin J. Whitehead, James R. Gossage, Charles E. McCulloch, Marianne Clancy, Negar Bagheri, Marie E. Faughnan, the Brain Vascular Malformation Consortium HHT Inves Tags: Research Paper Source Type: research
Measurement of Developmental and Behavioral Concerns in Toddlers with Tuberous Sclerosis Complex
TAND symptoms are very common in toddlers with TSC, and these symptoms may increase with age. The TAND Checklist is a useful tool for identifying behavioral concerns efficiently, but several items and sections are not suited to younger children. Results support the development of an abbreviated form of the TAND Checklist for toddlers. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 21, 2024 Category: Neurology Authors: Nicole M. McDonald, Sydney Jacobs, Carly Hyde, Connie Kasari, Shafali S. Jeste Tags: Research Paper Source Type: research
Anti-seizure medications normalize EEG functional connectivity and power in children with benign epilepsy with centrotemporal spikes
The decision to treat children with benign epilepsy with centrotemporal spikes (BECTS) using anti-seizure medications (ASM) is controversial. Our goal is to compare the effect of ASM treatment on the alteration of EEG functional connectivity and power across 4 frequency bands in BECTS children. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 21, 2024 Category: Neurology Authors: Min-Lan Tsai, Chuang-Chin Wang, Andy Yu-Der Wang, Feng-Chin Lee, Hsi Chang, Yen-Lin Liu, Tai-Tong Wong, Syu-Jyun Peng Tags: Research Paper Source Type: research
Symptom severity and health impacts of functional tic-like behaviours in youth
Youth with FTLB have unique healthcare needs and associations with anxiety, depression, sex and gender. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 21, 2024 Category: Neurology Authors: Lindsay Berg, Davide Martino, Z Paige L ’Erario, Tamara Pringsheim Tags: Research Paper Source Type: research
Underlying disorders in children with infection-related acute encephalopathy
Various factors contribute to the development of infection-related acute encephalopathy (AE) in children, such as infectious agents and chronic underlying disorders. We studied underlying disorders in children with AE to identify predisposing factors of AE. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 21, 2024 Category: Neurology Authors: Tomohiko Nakata, Jun Natsume, Hiroyuki Yamamoto, Yuji Ito, Takeshi Suzuki, Masahiro Kawaguchi, Anna Shiraki, Sumire Kumai, Fumi Sawamura, Ryosuke Suzui, Takamasa Mitsumatsu, Hajime Narita, Takeshi Tsuji, Tetsuo Kubota, Shinji Saitoh, Akihisa Okumura, Hiro Tags: Research Paper Source Type: research
Risk Factors for Term-Born Spastic Diplegic Cerebral Palsy: A Case Control Study
Antenatal (pregnancy complications, maternal disease, substance use) and perinatal (infections, cesarian section, and perinatal adversity) risk factors are associated with an increased risk of SDCP in term-born children, suggesting variable interactions between risk factors to provide a clinicopathologic framework that is different from SDCP observed in preterm-born children. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 20, 2024 Category: Neurology Authors: Amaar Marefi, Nafisa Husein, Mary Dunbar, Deborah Dewey, Nicole Letourneau, Maryam Oskoui, Adam Kirton, Michael Shevell, members of Canadian CP Registry Tags: Research Paper Source Type: research
Pediatric reversible cerebral vasoconstriction syndrome/posterior encephalopathy syndrome/post-streptococcal glomerulonephritis
We report for th e first time a pediatric case of RCVS and PRES secondary to acute post-streptococcal glomerulonephritis (APSGN). (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 16, 2024 Category: Neurology Authors: Yuki Kawashima, Shohei Ariji, Rui Aoyagi, Masahiro Noda, Kunihiro Oba, Masashi Ogasawara Tags: Short Communication Source Type: research
Accuracy of early neuroprognostication in pediatric severe traumatic brain injury
We describe a single-center study assessing clinicians ’ neuroprognostication accuracy. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 16, 2024 Category: Neurology Authors: Varun Sampat, John Whitinger, Katherine Flynn-O'Brien, Irene Kim, Binod Balakrishnan, Niyati Mehta, Rachel Sawdy, Namrata D. Patel, Rupa Nallamothu, Liyun Zhang, Ke Yan, Kimberley Zvara, Raquel Farias-Moeller Tags: Research Paper Source Type: research
Novel variant ANKRD11 gene mutation associated with drug-resistant epilepsy in KBG syndrome phenotype
KBG syndrome is a rare genetic disorder caused by mutations in the ANKRD11 gene. It is characterized by a macrodontia, short stature, distinctive craniofacial features, skeletal findings, intellectual disability, neurobehavioral anomalies. 1-3Additional findings associated with KBG syndrome including a prominent and elongated coccyx, wide fontanels, delayed speech development, hoarse voice, hearing loss, and ear lobe creases were described in the literature.4-7EEG abnormalities, with or without seizures, have been reported in about 50% of affected individuals. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 16, 2024 Category: Neurology Authors: Marija Babunovska, Tatjana Cepreganova Cangovska, Igor Kuzmanovski, Predrag Noveski, Dijana Plaseska-Karanfilska, Emilija Cvetkovska Tags: Research Paper Source Type: research
Expanding the phenotypic spectrum of TRAF7-related CAFDADD: report of eleven new cases and literature review.
We present a detailed description of eleven new TRAF7-related CAFDADD cases, featuring eight distinct variants, including a novel one. Phenotypic analysis and a comprehensive review of the 58 previously reported cases outline consistent clinical presentations, emphasizing dysmorphic features, developmental delay, endocrine manifestations, and cardiac defects. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 13, 2024 Category: Neurology Authors: Carmen Palma-Milla, Aina Prat-Planas, Emma Soengas-Gonda, M ónica Centeno-Pla, Jaime Sánchez-Pozo, Irene Lazaro-Rodriguez, Juan F. Quesada-Espinosa, Ana Arteche-Lopez, Jonathan Olival, Marta Pacio-Miguez, María Palomares-Bralo, Fernando Santos-Simarro, Tags: Research Paper Source Type: research
Retrospective Multicenter Cohort Study on Safety and Electroencephalographic Response to Lacosamide for Neonatal Seizures
There is growing evidence supporting the safety and effectiveness of lacosamide in older children. However, minimal data are available for neonates. We aimed to determine the incidence of adverse events associated with lacosamide use and explore the electroencephalographic seizure response to lacosamide in neonates. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 13, 2024 Category: Neurology Authors: Moninder Kaur, Levon Utidjian, Nicholas S. Abend, Kimberley Dickinson, Robert Roebling, Jill McDonald, Mitchell G. Maltenfort, Nadia Foskett, Sami Elmoufti, Rejean M. Guerriero, Badal G. Jain, Nathan M. Pajor, Suchitra Rao, Ren ée A. Shellhaas, Laurel Sl Tags: Research Paper Source Type: research
Editorial Board and Masthead
(Source: Pediatric Neurology)
Source: Pediatric Neurology - March 9, 2024 Category: Neurology Source Type: research
Table of Contents
(Source: Pediatric Neurology)
Source: Pediatric Neurology - March 9, 2024 Category: Neurology Source Type: research
An effort to identify genetic determinants in Wilson Disease siblings manifesting striking clinical heterogeneity: An exome profiling study of two Indian families
Wilson Disease (WD) is a rare autosomal recessive disorder of copper metabolism caused due to mutations in the copper transporter ATP7B. There is often a striking variability of clinical manifestations among patients with ATP7B mutations, including in siblings. This phenomenon may be caused by individual differences in copper accumulation in hepatocytes and intolerance to copper toxicity as governed by genetic variations in copper metabolism genes acting as modifier loci to the disease. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 7, 2024 Category: Neurology Authors: Arpan Saha, Shrishti Das, Samragni De, Tithi Dutta, Shubhrajit Roy, Atanu Biswas, Mainak Sengupta Tags: Research Paper Source Type: research
