Table of Contents
(Source: Pediatric Neurology)
Source: Pediatric Neurology - November 18, 2023 Category: Neurology Source Type: research
Tenecteplase in Pediatric Stroke: Ready or Not
Intravenous thrombolysis with tissue plasminogen activator (tPA) is used for off-label treatment of acute childhood stroke. Tenecteplase (TNK) is used to treat acute stroke in adults at many institutions, although there are extremely few data about TNK use in children. We aimed to characterize pediatric stroke experts ’ experience and preferences with regards to TNK use in children with stroke. (Source: Pediatric Neurology)
Source: Pediatric Neurology - November 17, 2023 Category: Neurology Authors: Jenny L. Wilson, Michaela Waak, Megan Barry, Lori C. Jordan, Lisa R. Sun Tags: Research Paper Source Type: research
Neurological and visual outcomes in infants and toddlers following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy
The majority of the studies investigated neurodevelopmental outcomes, while visual impairment is less explored in children with a history of neonatal (hypoxic-ischemic) encephalopathy. Our aim was to perform a detailed neurological and visual assessment and also to investigate the presence of cerebral visual impairment in infants and toddlers with neonatal encephalopathy. (Source: Pediatric Neurology)
Source: Pediatric Neurology - November 16, 2023 Category: Neurology Authors: E.Y. Imamoglu, Z. Acar, E.Y. Karatoprak, S.H. Ozumut, S.Y. Ocak, S. Imamoglu, F. Oval ı Tags: Research Paper Source Type: research
Long-Term Neurocognitive Outcomes in Pediatric Nonfatal Drowning: Results of a Family Caregiver Survey
This study reports neurocognitive outcomes for 154 children hospitalized following drowning. (Source: Pediatric Neurology)
Source: Pediatric Neurology - November 11, 2023 Category: Neurology Authors: Muslima S. Razaqyar, Eri Osta, Jonathan M. Towne, Mary D. Woolsey, Mariam Ishaque, Florence L. Chiang, Peter T. Fox Tags: Research Paper Source Type: research
Long-term Neurocognitive Outcomes in Pediatric Non-Fatal Drowning: Results of a Family Caregiver Survey
This study reports neurocognitive outcomes for 154 children hospitalized following drowning. (Source: Pediatric Neurology)
Source: Pediatric Neurology - November 11, 2023 Category: Neurology Authors: Muslima S. Razaqyar, Eri Osta, Jonathan M. Towne, Mary D. Woolsey, Mariam Ishaque, Florence L. Chiang, Peter T. Fox Tags: Research Paper Source Type: research
Adolescent sport-related concussion and the associated neurophysiological changes: A systematic review
Sport-related concussion (SRC) has been shown to induce cerebral neurophysiological deficits, quantifiable with electroencephalography (EEG). As the adolescent brain is undergoing rapid neurodevelopment, it is fundamental to understand both the short- and long-term ramifications SRC may have on neuronal functioning. The current systematic review sought to amalgamate the literature regarding both acute/subacute ( ≤28-days) and chronic (>28-days) effects of SRC in adolescents via EEG, and the diagnostic accuracy of this tool. (Source: Pediatric Neurology)
Source: Pediatric Neurology - November 3, 2023 Category: Neurology Authors: Joel S. Burma, Andrew P. Lapointe, Megan Wilson, Linden C. Penner, Courtney M. Kennedy, Kailey T. Newel, Olivia A. Galea, Lauren N. Miutz, Jeff F. Dunn, Jonathan D. Smirl Tags: Review Article Source Type: research
Nerve Transfer Surgery in Acute Flaccid Myelitis: Prognostic Factors, Long-Term Outcomes, Comparison to Natural History
The objectives of this study were to evaluate surgical efficacy, assess which clinical and neurophysiological data are valuable for preoperative planning, and report long-term outcomes. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 31, 2023 Category: Neurology Authors: Glenn S. Rivera, Jesse A. Stokum, Janet Dean, Cristina L. Sadowsky, Allan J. Belzberg, Matthew J. Elrick Tags: Research Paper Source Type: research
Self- and Caregiver-Reported Participation, Quality of Life, and Related Mood and Behavior Challenges in People Living With Dystrophinopathies
Previous studies of quality of life (QOL), mood, and behavior in muscular dystrophy focus on caregiver perceptions. This cross-sectional study aims to determine the prevalence of clinically significant mood and behavior problems by both patient and caregiver report and assess relationship between mood/behavior and QOL. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 30, 2023 Category: Neurology Authors: Anna Jesus, Carolyn Bennett, Chelsea Masterson, Laurie Brenner, Rebecca Scharf Tags: Research Paper Source Type: research
Self- and Caregiver Reported Participation, Quality of Life and Related Mood and Behavior Challenges in People Living with Dystrophinopathies
Previous studies of quality of life (QOL), mood, and behavior in Muscular Dystrophy (MD) focus on caregiver perceptions. This cross-sectional study aims to determine the prevalence of clinically-significant mood and behavior problems by both patient and caregiver report,and assess relationship between mood/behavior and QOL. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 30, 2023 Category: Neurology Authors: Anna Jesus, Carolyn Bennett, Chelsea Masterson, Laurie Brenner, Rebecca Scharf Tags: Research Paper Source Type: research
The Important Role of Hemispherotomy for Rasmussen Encephalitis: Clinical and Functional Outcomes
Rasmussen encephalitis (RE) is characterized by pharmacoresistant epilepsy and progressive neurological deficits concurrent with unilateral hemispheric atrophy. Evidence of an inflammatory autoimmune process has been extensively described in the literature; however, the precise etiology of RE is still unknown. Despite data supporting a beneficial effect of early immunosuppressive and immunomodulatory interventions, surgical disconnection of the affected hemisphere is considered the treatment of choice for these patients. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 27, 2023 Category: Neurology Authors: Ursula Thom é, Larissa A. Batista, Renata P. Rocha, Vera C. Terra, Ana Paula A. Hamad, Americo C. Sakamoto, Antônio C. Santos, Marcelo V. Santos, Hélio R. Machado Tags: Research Paper Source Type: research
Childhood Absence Epilepsy- Electroclinical Profile and Prevalence of Attention-Deficit/Hyperactivity Disorder Among a Cohort of 47 Children
We aimed to find the proportion of attention-deficit/hyperactivity disorder (ADHD) among children with childhood absence epilepsy (CAE) and to describe their electroclinical features. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 27, 2023 Category: Neurology Authors: Merin Eapen, Mary Iype, Geetha Saradakutty, Bineej B. Jayan, Mini Sreedharan, Shahanaz Ahamed, Elizabeth Preethi Thomas, Azmi Habeeb, Anchu Cherian Tags: Research Paper Source Type: research
The important role of hemispherotomy for Rasmussen Encephalitis: Clinical and Functional outcomes.
First described by Theodore Rasmussen and co-workers in 1958 (1), Rasmussen ’s encephalitis (RE) is characterized by unilateral inflammation of the cerebral cortex, drug-resistant epilepsy, and progressive neurological and cognitive deterioration (2). It is a rare neurological disorder whose pathophysiology is associated with several immunopathological events, including T -cell, autoantibody and microglia responses to antigenic epitopes (2, 3). (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 27, 2023 Category: Neurology Authors: Ursula Thom é, Larissa A. Batista, Renata P. Rocha, Vera C. Terra, Ana Paula A. Hamad, Americo C. Sakamoto, Antônio C. Santos, Marcelo V. Santos, Hélio R. Machado Source Type: research
Childhood Absence Epilepsy- Electroclinical profile and prevalence of Attention Deficit Hyperactivity Disorder among a cohort of 47 children
We aimed to find the proportion of Attention Deficit Hyperactivity Disorder (ADHD) among children with Childhood Absence Epilepsy (CAE) and to describe their electro-clinical features. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 27, 2023 Category: Neurology Authors: Dr.Merin Eapen, Dr. Mary Iype, Dr. Geetha S, Bineej B. Jayan, Dr. Mini Sreedharan, Dr.Shahanaz Ahamed, Dr. Elizabeth Preethi Thomas, Dr.Azmi Habeeb, Dr.Anchu Cherian Tags: Research Paper Source Type: research
Mild Neurological Manifestations Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Children During the Omicron Wave in Singapore: A Retrospective Cohort Review
Neurological complications with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant have been reported in adults; however, there are little data in the pediatric population. We aimed to report on the prevalence and clinical characteristics of children with neurological symptoms during the SARS-CoV-2 omicron wave. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 26, 2023 Category: Neurology Authors: Velda X. Han, Shannon M. Seet, Belinda X.Y. Quek, Jeremy B. Lin, Furene S. Wang, Stacey K.H. Tay, Olivia Leow, Rie Aoyama, Si Min Chan Tags: Research Paper Source Type: research
Diagnostic Yield of Epilepsy-Genes Sequencing and Chromosomal Microarray in Pediatric Epilepsy
Around 40% of individuals with epilepsy have an underlying identifiable genetic etiology. Common methods for epilepsy genetic testing are chromosomal microarray (CMA) and epilepsy-genes sequencing (EGS). Historically, CMA was the first-line test for patients with epilepsy, but recent studies have shown that EGS has a superior diagnostic yield. To further develop optimal testing algorithms for epilepsy, we compared these tests ’ diagnostic yields, and explored how they are influenced by the age of onset and phenotype complexity. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 26, 2023 Category: Neurology Authors: Kelly C. Burk, Maki Kaneko, Catherine Quindipan, My H. Vu, Maritza Feliz Cepin, Jonathan D. Santoro, Michele Van Hirtum-Das, Deborah Holder, Gordana Raca Tags: Research Paper Source Type: research
