Crystal-induced nephrotoxicity associated with acyclovir use in paediatric patient
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Abin Chandrakumar, Ceriyac Jose Mundadan, Dilip Chandrasekhar, Sabin Tharappel Sojan, Sharanya Nair Drug-induced nephrotoxicity has evolved as one of the significant causes of renal failure in the contemporary setting accounting up to 20%. Acyclovir is an antiviral agent, which has the potential for precipitating transient crystal-induced nephrotoxicity, especially in elderly, euvolemic or renal patients when given as rapid intravenous bolus. The current case depicts evolution and management of transient nephropath...
Source: Pediatric Infectious Disease - May 26, 2016 Category: Pediatrics Source Type: research

Unusual presentation of enteric fever in an 11-year-old female child
We report a case of enteric fever that presented at the start as acute gastritis and then went on to develop acute pancreatitis, which is a rare complication of enteric fever, along with capillary leak syndrome in the acute phase mimicking dengue shock syndrome. This unusual presentation has not been reported in Indian or foreign literature. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - May 26, 2016 Category: Pediatrics Source Type: research

Pediatric gastrointestinal basidiobolomycosis
Publication date: Available online 4 April 2016 Source:Pediatric Infectious Disease Author(s): A. Eghbalkhah, M. Habibi, M. Lesanpezeshki, Sh. Shahinpour Basidiobolomycosis is a rare fungal disease caused by Basidiobolus ranarum, which is an environmental saprophyte. It is a chronic inflammatory disease that is generally restricted to the subcutaneous tissue and rarely involves the gastrointestinal tract. With the intent to spread awareness of this potentially life threatening and rare infection, we report a 4-year-old boy presenting with abdominal pain and fever with eventual diagnosis of gastrointestinal basi...
Source: Pediatric Infectious Disease - May 26, 2016 Category: Pediatrics Source Type: research

Orbital entomophthoromycosis in a toddler – An unusual presentation/a case report
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Mourouguessine Vimal, Marie Therese Manipadam, Soosan Jacob Entomophthoromycosis is a rare fungal infection seldom occurring in humans. Only very few cases of entomophthoromycosis exclusively involving the orbit have been reported in the literature. We are reporting a case of entomophthoromycosis in a toddler who presented with swelling of the left orbit following trauma to the left eye. The nonspecific clinical signs and symptoms of the patient posed us diagnostic dilemma. Histopathological examination helped us to ar...
Source: Pediatric Infectious Disease - April 5, 2016 Category: Pediatrics Source Type: research

’Pediatric gastrointestinal Basidiobolomycosis’
Publication date: Available online 4 April 2016 Source:Pediatric Infectious Disease Author(s): A. Eghbalkhah, M. Habibi, M. Lesanpezeshki, Sh. Shahinpour Basidiobolomycosis is a rare fungal disease caused by basidiobolus ranarum which is an environmental saprophyte. It is a chronic inflammatory disease that is generally restricted to the subcutaneous tissue and rarely involves gastrointestinal tract. With the intent to spread the awareness of this potentially life threatening and rare infection, we report a 4 years old boy presenting with abdominal pain and fever with eventual diagnosis of gastrointestinal basi...
Source: Pediatric Infectious Disease - April 4, 2016 Category: Pediatrics Source Type: research

Lab diagnosis of brucellosis
This article reviews the various culture methods, serological tests and newer diagnostic methods available in making a laboratory diagnosis of brucellosis along with their advantages and drawbacks. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Rotavirus infection markers in children with rotaviral gastroenteritis and their relation to disease severity
Conclusion Accordingly, we can conclude that rotaviral antigenemia and viremia were common in children with rotaviral diarrhea, however, the impact of rotavirus antigenemia/viremia on clinical manifestations of infection is unknown. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Cytomegalovirus Infection in Children after Bone Marrow Transplantation: Risk factors, Clinical aspects and Outcomes
Conclusions Antigenemia-guided pre-emptive strategy with ganciclovir was very affective and CMV reactivation tended not to affect the outcome in our study cohort. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Crystal Induced Nephrotoxicity Associated with Acyclovir Use in Paediatric Patient
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Abin Chandrakumar, Pretty G Tharakan, Bittu Thomas, Anu Albert, Teena Jacob Drug induced nephrotoxicity has evolved as one of the significant causes of renal failure in the contemporary setting accounting up to 20%. Acyclovir is an antiviral agent which has potential for precipitating transient crystal induced nephrotoxicity especially in elderly, euvolemic or renal patients when given as rapid intravenous bolus. The current case depicts evolution and management of transient nephropathy in a paediatric patient trea...
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Unusual presentation of enteric fever in 11 year old female child
We report a case of enteric fever which presented to start with as acute gastritis and then went on to develop acute pancreatitis which is a rare complication of enteric fever; along with capillary leak syndrome in the acute phase mimicking dengue shock syndrome. This unusual presentation has not been reported in Indian or foreign literature. (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Orbital entomophthoromycosis in a toddler–an unusual presentation/a case report
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Mourouguessine Vimal, Marie Therese Manipadam, Soosan Jacob Entomophthoromycosis is a rare fungal infection seldom occurring in humans. Only very few cases of Entomophthoromycosis exclusively involving the orbit have been reported in the literature. We are reporting a case of Entomophthoromycosis in a toddler who presented with swelling of the left orbit following trauma to the left eye. The nonspecific clinical signs and symptoms of the patient posed us diagnostic dilemma. Histopathological examination helped us to ar...
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Disseminated Bacille Calmette-Guérin Disease in an Infant with a Novel bi-allelic Mutation in Interferon Gamma Receptor-1 Gene
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): C.K. Indumathi, Bijayanti Mishra, A.S. Caroline Deswarte, Jacinta Bustamante (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Fixed dose combination of Anti-tubercular drugs: Time to reformulate
Publication date: Available online 26 March 2016 Source:Pediatric Infectious Disease Author(s): Sumit Mehndiratta (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 26, 2016 Category: Pediatrics Source Type: research

Rapid diagnosis of childhood TB: Can we meet pediatric TB requirements?
Publication date: Available online 3 March 2016 Source:Pediatric Infectious Disease Author(s): Chaitali Nikam, Asawari Chavan, Swapna Naik, Archana Khillari, Lancelot Pinto, Anjali Shetty, Camilla Rodrigues (Source: Pediatric Infectious Disease)
Source: Pediatric Infectious Disease - March 5, 2016 Category: Pediatrics Source Type: research

A Case Report of Bartonella Endocarditis with Pancytopenia
Publication date: Available online 2 March 2016 Source:Pediatric Infectious Disease Author(s): Heather Riebel, Michael Hainstock, Jane Atkins A nine year old male with history of complex congenital heart disease presented with intermittent fevers and chills of three month duration along with pancytopenia. Given a high suspicion for endocarditis despite negative blood cultures, a literature search for culture negative endocarditis yielded the possibility of less common organisms, including zoonotic agents. There were only isolated case reports of Bartonella causing pancytopenia. Further testing revealed positive B...
Source: Pediatric Infectious Disease - March 3, 2016 Category: Pediatrics Source Type: research