A new perspective on the proper timing of radiotherapy during CDK4/6 inhibitor therapy in patients with "bone-only" metastatic breast cancer
Pathol Oncol Res. 2023 Oct 11;29:1611369. doi: 10.3389/pore.2023.1611369. eCollection 2023.ABSTRACTThe vast majority of hormone positive and HER2 negative advanced breast cancers can be controlled well by endocrine therapy combined with the groundbreaking use of CDK4/6 inhibitors in the metastatic first-line setting. Approximately 50%-60% of these patients have "bone-only" metastatic disease. In oligometastatic cases or if a certain number of uncontrolled lesions develop during the aforementioned therapy, ablative radiotherapy can be delivered or, in symptomatic cases, urgent irradiation is needed with palliative intent. T...
Source: Pathology Oncology Research - October 27, 2023 Category: Pathology Authors: Ilona Tornyi Peter Árkosy Ildik ó Horváth Andrea Furka Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing
Conclusion: This study demonstrates a high concordance between integrated ctDNA diagnosis and the final diagnosis of gliomas, highlighting the practicability of NGS based detection of mutations of CSF in assisting integrated diagnosis of gliomas, especially glioblastoma.PMID:37822669 | PMC:PMC10562547 | DOI:10.3389/pore.2023.1611391 (Source: Pathology Oncology Research)
Source: Pathology Oncology Research - October 12, 2023 Category: Pathology Authors: Qiang Wang Qiujin Liang Wuting Wei Wenhao Niu Chong Liang Xiaoliang Wang Xiaoxuan Wang Hao Pan Source Type: research

A unique case of AH-dominant type nodular pulmonary amyloidosis presenting as a spontaneous pneumothorax: a case report and review of the literature
We present a case of an 81 years-old male with nodular pulmonary AH-dominant type amyloidosis who presented with spontaneous pneumothorax. For a deeper understanding of the subject, this study also provides a review of the literature on cases with nodular pulmonary amyloidosis in relation to precise amyloid fibril subtyping. Since it is often a difficult process, accurate amyloid type identification is rarely accomplished. However, this information is very helpful for identifying the underlying disease process (if any) and outlining the subsequent diagnostic and treatment steps. Even so, it is crucial to be aware of this u...
Source: Pathology Oncology Research - October 9, 2023 Category: Pathology Authors: Valeria Skopelidou Pavel Hurn ík Lubom ír Tulinský Vladimir Židlík Ji ří Lenz Patricie Delongov á Helena Hornychov á Patrik Flodr Tom áš Jelínek Ludmila Muro ňová Du šan Holub Petr D žubák Mari án Hajdúch Source Type: research

A unique case of AH-dominant type nodular pulmonary amyloidosis presenting as a spontaneous pneumothorax: a case report and review of the literature
We present a case of an 81 years-old male with nodular pulmonary AH-dominant type amyloidosis who presented with spontaneous pneumothorax. For a deeper understanding of the subject, this study also provides a review of the literature on cases with nodular pulmonary amyloidosis in relation to precise amyloid fibril subtyping. Since it is often a difficult process, accurate amyloid type identification is rarely accomplished. However, this information is very helpful for identifying the underlying disease process (if any) and outlining the subsequent diagnostic and treatment steps. Even so, it is crucial to be aware of this u...
Source: Pathology Oncology Research - October 9, 2023 Category: Pathology Authors: Valeria Skopelidou Pavel Hurn ík Lubom ír Tulinský Vladimir Židlík Ji ří Lenz Patricie Delongov á Helena Hornychov á Patrik Flodr Tom áš Jelínek Ludmila Muro ňová Du šan Holub Petr D žubák Mari án Hajdúch Source Type: research

A unique case of AH-dominant type nodular pulmonary amyloidosis presenting as a spontaneous pneumothorax: a case report and review of the literature
We present a case of an 81 years-old male with nodular pulmonary AH-dominant type amyloidosis who presented with spontaneous pneumothorax. For a deeper understanding of the subject, this study also provides a review of the literature on cases with nodular pulmonary amyloidosis in relation to precise amyloid fibril subtyping. Since it is often a difficult process, accurate amyloid type identification is rarely accomplished. However, this information is very helpful for identifying the underlying disease process (if any) and outlining the subsequent diagnostic and treatment steps. Even so, it is crucial to be aware of this u...
Source: Pathology Oncology Research - October 9, 2023 Category: Pathology Authors: Valeria Skopelidou Pavel Hurn ík Lubom ír Tulinský Vladimir Židlík Ji ří Lenz Patricie Delongov á Helena Hornychov á Patrik Flodr Tom áš Jelínek Ludmila Muro ňová Du šan Holub Petr D žubák Mari án Hajdúch Source Type: research