Tubular adenomas with clear cell change in the colorectum: A case with four lesions and a review of the literature
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - January 12, 2018 Category: Pathology Source Type: research
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Pathology International, Ahead of Print. (Source: Pathology International)
Source: Pathology International - January 12, 2018 Category: Pathology Source Type: research
Chronic recurrent pulmonary thromboembolism in a patient with essential thrombocythemia, complicating acute right ventricular infarct
Pathology International,Volume 68, Issue 3, Page 202-204, March 2018. (Source: Pathology International)
Source: Pathology International - January 10, 2018 Category: Pathology Source Type: research
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Pathology International,Volume 68, Issue 3, Page 202-204, March 2018. (Source: Pathology International)
Source: Pathology International - January 10, 2018 Category: Pathology Source Type: research
Notice to Contributors
(Source: Pathology International)
Source: Pathology International - January 2, 2018 Category: Pathology Tags: Notice to Contributors Source Type: research
Gastrointestinal follicular lymphoma: Current knowledge and future challenges
The gastrointestinal (GI) tract is the most commonly involved site of extranodal follicular lymphoma (FL). GI‐FL shows very indolent clinical behavior and localized at GI tract without any progression or transformation compared to nodal FL. The most frequently involved site of the GI tract was the duodenum followed by the jejunum and ileum, and only 15% of FL arising in the second part of the duodenum were localized there without scattered very small daughter lesions in other GI tract examined by double‐balloon endoscopy. The typical macroscopic appearance of GI‐FL was multiple white nodules. Microscopically, neoplas...
Source: Pathology International - January 2, 2018 Category: Pathology Authors: Katsuyoshi Takata, Tomoko Miyata ‐Takata, Yasuharu Sato, Masaya Iwamuro, Hiroyuki Okada, Akira Tari, Tadashi Yoshino Tags: Review Article Source Type: research
Issue Information
(Source: Pathology International)
Source: Pathology International - January 2, 2018 Category: Pathology Tags: Issue Information Source Type: research
Mitosis count and number of cancer cells in cases of primary pulmonary adenocarcinoma: Correlations among phosphorylated histone 3, number of cancer cells, nuclear grade, pathologic features and prognosis
Immunohistochemistry findings for the phosphorylated form of histone 3 (pHH3) have been shown to be a reliable mitosis‐specific marker. We evaluated the correlation between pHH3‐stained mitotic figures (PHMFs) and clinical outcome, and compared the results with findings for numbers of PHMFs and cancer cells. The primary tumor was obtained from 113 patients with pulmonary adenocarcinomas (≤2 cm maximum dimension). All specimens were stained with pHH3, then the number of cancer cells in each was determined. Cases with a cancer‐cell index ≥1000 showed worse recurrence‐free survival as compared to those with a va...
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Takashi Inoue, Yoshimasa Nakazato, Yoko Karube, Sumiko Maeda, Satoru Kobayashi, Masayuki Chida Tags: Original Article Source Type: research
Nuclear pseudoinclusions in melanoma cells: prognostic fact or artifact? The possible role of Golgi phosphoprotein 3 overexpression in nuclear pseudoinclusions generation
We examined the presence of NPIs in H&E‐stained tissue sections form 96 melanomas and analyzed statistical associations with important clinicopathological parameters and tissue immunoreactivity for selected proteins involved in epithelial‐mesenchymal transition (SPARC, N‐cadherin), cell adhesion and mobility (ALCAM, ADAM‐10), regulation of mitosis (PLK1), cell survival (FOXP1) and functioning of Golgi apparatus (GOLPH3, GP73). NPIs were observed in 20% of melanomas and their presence correlated with high mitotic rate and ulceration of the tumor, but not with Breslow thickness, histologic type, or presence of me...
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Piotr Donizy, Maciej Kaczorowski, Przemyslaw Biecek, Agnieszka Halon, Rafal Matkowski Tags: Original Article Source Type: research
Stromal tiny black dots, like “sugar‐coated”, of von Kossa stain is a diagnostic clue to hyalinizing trabecular tumor of the thyroid gland
Hyalinizing trabecular tumor (HTT) is a rare low‐grade tumor, and a prominent feature is the basement membranous stroma. We assume that such characteristic stromal findings of HTT are related to calcium deposition, and examined HTT samples by von Kossa special staining. There has been no report describing von Kossa special staining for such stroma. We collected 12 cases of HTT and 30 cases of papillary thyroid carcinoma (PTC) that had matched age, gender, tumor size, and surgical procedure characteristics as a control group. We compared the staining pattern and degree of von Kossa positivity between HTT and PTC, and a gr...
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Rumi Hino, Noriko Motoi, Kazutoshi Toda, Aya Ebina, Keiko Yamada, Miyoko Higuchi, Mitsuyoshi Hirokawa, Yuichi Ishikawa Tags: Original Article Source Type: research
Fulminant adenovirus hepatitis with adenovirus ‐associated esophagitis complicating malignant lymphoma
(Source: Pathology International)
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Yota Murase, Nagako Maeda, Harutaka Katano, Toyonori Tsuzuki Tags: Letter to the Editor Source Type: research
Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease
The peroxiredoxin (PRDX) family, a new family of proteins with a pivotal antioxidative function, is ubiquitously synthesized and abundantly identified in various organisms. In contrast to the intracellular localization of other family members (PRDX1/2/3/5/6), PRDX4 is the only known secretory form and protects against oxidative damage by scavenging reactive oxygen species in both the intracellular (especially the endoplasmic reticulum) compartments and the extracellular space. We generated unique human PRDX4 (hPRDX4) transgenic (Tg) mice on a C57BL/6J background and investigated the critical and diverse protective roles of...
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Sohsuke Yamada, Xin Guo Tags: Review Article Source Type: research
Tubular adenomas with clear cell change in the colorectum: A case with four lesions and a review of the literature
(Source: Pathology International)
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Chika Miyasaka, Mitsuaki Ishida, Chisato Ohe, Yoshiko Uemura, Yugo Ando, Toshiro Fukui, Koji Tsuta Tags: Letter to the Editor Source Type: research
Chronic recurrent pulmonary thromboembolism in a patient with essential thrombocythemia, complicating acute right ventricular infarct
(Source: Pathology International)
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Masayuki Shintaku, Satoshi Miura, Kohsuke Asagoe, Chikao Yutani Tags: Letter to the Editor Source Type: research
SMARCB1/INI1/BAF47 ‐ deficient pleural malignant mesothelioma with rhabdoid features
Malignant mesothelioma (MM) with rhabdoid features is an MM variant. Fifteen cases have been reported previously, all of which were combined with other types of MM. Herein, we report an autopsy case of pleural MM with monomorphic rhabdoid features. The patient was a 62‐year‐old male without a history of asbestos exposure. An autopsy revealed a soft, granular tumor that replaced the entire left pleura and had invaded to the diaphragm and lower lobe of the lung. The tumor cells, which had eosinophilic plump cytoplasm and eccentric nuclei, were loosely cohesive. Immunohistochemistry showed that the cells were diffusely po...
Source: Pathology International - January 1, 2018 Category: Pathology Authors: Noriko Kimura, Masaru Hasegawa, Kenzo Hiroshima Tags: Case Report Source Type: research
