Association of Bilateral oophorectomy with incidence of Parkinson's disease: A systematic review and meta-analysis
Current evidence in the literature is inconclusive due to conflicting results with regards to an association between B/L (B/L) oophorectomy and Parkinson's disease (PD). We included large, powered studies to assess the association of PD in women who have undergone B/L oophorectomy. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 8, 2024 Category: Neurology Authors: Abraish Ali, Syeda Areeba Tabassum, Zuhaa Rehman, Mahek Ramani, Khadija Ali, Ahmed Mustafa Siddiqui, Umer Shahid, Usama Sakrani, Hania Samhan, Syeda Sabahat, Shayan Marsia Tags: Short communication Source Type: research
Abnormal supplementary motor areas are associated with idiopathic and acquired blepharospasm
Blepharospasm is a common form of focal dystonia characterized by excessive and involuntary spasms of the orbicularis oculi. In addition to idiopathic blepharospasm, lesions in various brain regions can also cause acquired blepharospasm. Whether these two types of blepharospasm share a common brain network remains largely unknown. Herein, we performed lesion coactivation network mapping, based on meta-analytic connectivity modeling, to test whether lesions causing blepharospasm could be mapped to a common coactivation brain network. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 8, 2024 Category: Neurology Authors: Jinping Xu, Xiaodong Zhang, Qinxiu Cheng, Haoran Zhang, Linchang Zhong, Yuhan Luo, Yue Zhang, Zilin Ou, Zhicong Yan, Kangqiang Peng, Gang Liu Source Type: research
Using the neurological health of former professional American football players to transform primary care
In this issue (Parkinsonism Relat Disord., 2023 Nov 14:105903 (online)), Dr. Adler and members of the DIAGNOSE CTE consortium present intriguing data related to the potential relationship between playing collegiate and professional football with Parkinson ’s disease and parkinsonism. As someone who played Division III football and coached his son’s youth football team, this study was of great personal and scientific interest. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 7, 2024 Category: Neurology Authors: Jay L. Alberts Source Type: research
Childhood-onset writer's cramp, with later ataxia: A clue to COQ8A-related disorders
Tonholo Silva and colleagues report 2 illustrative cases within a single family of childhood-onset writer's cramp and subsequent cerebellar ataxia caused by COQ8A mutations [1]. This is a very uncommon presentation and is potentially treatable with coenzyme-Q10 supplementation. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 7, 2024 Category: Neurology Authors: Christopher D. Stephen Source Type: research
Racial disparities in hospitalization characteristics among Native Hawaiians, Pacific Islanders and Asian American subgroups with Parkinson's disease
Differences among Native Hawaiians/Pacific Islanders (NHPI) and Asian American (AA) subgroups have not been adequately studied in Parkinson's disease (PD). (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 1, 2024 Category: Neurology Authors: Michiko Kimura Bruno, Masako Matsunaga, Emma Krening, Kazuma Nakagawa, John Chen, Todd Seto, Fay Gao, Caroline Tanner, G. Webster Ross Tags: Short communication Source Type: research
Patterns of regional cerebral hypoperfusion in early Parkinson's disease: Clinical implications
This study aimed to investigate whether regional cerebral perfusion patterns on early-phase 18F-FP-CIT PET scans, which is typically coupled to cerebral metabolism, predict the long-term prognosis of Parkinson's disease (PD). (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 1, 2024 Category: Neurology Authors: Seok Jong Chung, Su Hong Kim, Chan Wook Park, Hye Sun Lee, Mijin Yun, Yun Joong Kim, Young H. Sohn, Yong Jeong, Phil Hyu Lee Source Type: research
Current practices of burst vs. spaced physical therapy applied to Parkinson's disease
Parkinson's disease (PD) results in progressive worsening of mobility deficits which may profoundly impact quality of life, caregiver burden, and healthcare utilization [1,2]. To mitigate PD symptoms, physical therapy (PT) is commonly prescribed in conjunction with pharmacotherapy [1]. PT for neurological disorders is most commonly prescribed as a ‘burst’ of short-term, closely spaced visits over 6–12 weeks [3]. A recent pilot randomized clinical trial suggests patients with PD may be more likely to maintain mobility when receiving ‘spaced’ PT sessions over 6 months or longer when compared to the same number of v...
Source: Parkinsonism and Related Disorders - February 1, 2024 Category: Neurology Authors: Jennifer H. LeLaurin, Ramzi G. Salloum, Michael S. Okun Tags: Correspondence Source Type: research
Focused ultrasound therapy: Back to the future
The surgical treatment of movement disorders, primarily for tremor, started with radiofrequency lesioning of the globus pallidus and thalamus in the 1950s [1]. While this became a state-of-the-art treatment over the following decades, bilateral lesions were associated with significant side effects such as gait, balance, and speech disturbances [2]. In the 70's, radiosurgery with the gamma knife showed promise because the procedure was incisionless. However, it used ionizing radiation, and the target could not be confirmed in real-time, because the effect was delayed by around six months. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - February 1, 2024 Category: Neurology Authors: Leo Verhagen Metman, Mariana H.G. Monje, Jos é A. Obeso, Raúl Martínez-Fernández Tags: Review article Source Type: research
Connectome-based predictive modelling estimates individual cognitive status in Parkinson's disease
The progressive nature of Parkinson's disease (PD) affords emphasis on accurate early-stage individual-level assessment of risk and intervention appropriateness. In PD, cognitive impairment (CI) may follow or precede motor symptoms but are generally underdetected. In addition to impeding daily functioning and quality of life, CIs increase the risk for later conversion to dementia, providing a pressing need to develop novel tools to detect and interpret them. Connectome-based predictive modelling (CPM) is an emerging machine-learning approach to individual prediction that holds translational promise due to its noninvasivene...
Source: Parkinsonism and Related Disorders - January 31, 2024 Category: Neurology Authors: Alexander Tobias Ysb æk-Nielsen Source Type: research
Support needs of people with multiple system atrophy
Multiple system atrophy (MSA) is a neurodegenerative disease causing parkinsonism, autonomic disturbances, gait impairment and mood disorders. The progressive nature of MSA results in a significant deterioration in quality of life for patients. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - January 30, 2024 Category: Neurology Authors: Julia LY. Cheong, Zhao HK. Goh, Anette Schrag, Multiple System Atrophy Trust Tags: Short communication Source Type: research
The missing piece of the puzzle – The key role of the dietitian in the management of Parkinson's disease
The current paradigm for the multidisciplinary management of Parkinson's Disease (PD) does not include regular nutritional assessment despite research showing that 90 % of people living with Parkinson's (PwP) lack access to basic dietetic services. Since many non-motor symptoms such as dysphagia, constipation and orthostatic hypotension and PD complications such as weight loss and sarcopenia can be improved through dietary intervention, dietitians are a critic al missing piece of the PD management puzzle. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - January 30, 2024 Category: Neurology Authors: Richelle Flanagan, Carley Rusch, Fiona E. Lithander, Indu Subramanian Tags: Review article Source Type: research
The MemTrax memory test for detecting and assessing cognitive impairment in Parkinson's disease
The objective of the study is to assess the clinical utility of the MemTrax Memory Test in detecting cognitive impairment in patients with PD. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - January 29, 2024 Category: Neurology Authors: Yanmei Liu, Lei Wu, Weineng Chen, Fengjuan Su, Ganqiang Liu, Xianbo Zhou, Curtis B. Ashford, Feng Li, J. Wesson Ashford, Zhong Pei, Wenbiao Xian Source Type: research
Cervical motion alterations and brain functional connectivity in cervical dystonia
This study aims to assess kinematic and resting-state functional connectivity (RS-FC) characteristics in CD patients relative to healthy controls. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - January 27, 2024 Category: Neurology Authors: Elisabetta Sarasso, Daniele Emedoli, Andrea Gardoni, Lucia Zenere, Elisa Canu, Silvia Basaia, Alberto Doretti, Nicola Ticozzi, Sandro Iannaccone, Stefano Amadio, Ubaldo Del Carro, Massimo Filippi, Federica Agosta Source Type: research
Validation study of the Japanese version of the King's Parkinson's Disease Pain Scale and the King's Parkinson's Disease Pain Questionnaire
The King's Parkinson's Disease Pain Scale (KPPS)/King's Parkinson's Disease Pain Questionnaire (KPPQ) was developed as a tool to quantitatively assess pain in patients with Parkinson's disease (PwPD). Here, we conducted a Japanese multicenter validation study to verify the reliability of KPPS/KPPQ in Japanese PwPD. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - January 26, 2024 Category: Neurology Authors: Kanako Kurihara, Shinsuke Fujioka, Yasuaki Mizutani, Hirohisa Watanabe, Kazuhiro Iwaoka, Tetsuya Maeda, Morinobu Seki, Toshiki Tezuka, Jin Nakahara, Takuya Konno, Takanobu Ishiguro, Osamu Onodera, Yuri Asano, Kazushi Takahashi, Alexandra Rizos, K. Ray Cha Source Type: research
Editorial Board
(Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - January 18, 2024 Category: Neurology Source Type: research
