Hungarian ERCP registry for quality control and benchmarking
Objectives To develop a web-based ERCP registry which is easy to use and captures relevant procedure-related information. The primary aim of the registry is the long-term monitoring of outcome data of ERCP. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: D ániel Pécsi, Szilárd Gódi, Ferenc Pakodi, Andrea Szentesi, Péter Hegyi, Áron Vincze Tags: 6. Endoscopy Source Type: research
Prevalence of cystic lesions and other morphological pancreatic abnormalities in type 2 diabetes mellitus patients
Objectives To determine the prevalence of pancreatic cystic lesions and other morphological changes on MRI/MRCP in a cohort of type 2 DM patients. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Kasper Overbeek, Nanda Krak, Indra Pieters, Mark Smits, Rosa Bent, Dani ël Van Raalte, Marco Bruno, Djuna Cahen Tags: 7. Cystic lesions of the pancreas Source Type: research
T cells infiltrates evolve during pancreatic carcinogenesis of intraductal papillary mucinous neoplasms
Objectives To investigate the clinicopathological significance of the immune microenvironment, especially T cell subpopulations, in intraductal papillary mucinous neoplasms (IPMNs), and the immunological characteristics associated with progression from low-grade IPMN to invasive carcinoma. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Katharina Zamzow, Susanne Roth, Max Heckler, Jiaqu Cui, Mathias Heikenw älder, Matthias Gaida, Markus Büchler, Christoph W. Michalski, Thilo Hackert Tags: 7. Cystic lesions of the pancreas Source Type: research
Reducing pancreatic cyst surveillance: development of the Dutch American Risk stratification Tool (DART-I) to identify IPMN with low risk to progress and fulfill resection criteria
Objectives To develop a score chart to identify IPMN with low risk to progress and fulfill resection criteria. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Kasper Overbeek, Maaike Alblas, Valerie Gausman, Pujan Kandel, Christian Brooks, Priscilla Van Riet, Michael Wallace, Tamas Gonda, Djuna Cahen, Marco Bruno Tags: 7. Cystic lesions of the pancreas Source Type: research
Serum Protein profile in IPMN
Objectives The incidence of intraductal papillary mucinous neoplasm (IPMN) is increasing and thereby the number of patients under surveillance. There is a need for easily available serum biomarkers to distinguish patients with low or moderate grade dysplasia from those with high grade dysplasia or IPMN-associated cancer needing surgery. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Heini Nieminen, Mayank Saraswat, Sakari Joenv äärä, Ari Ristimäki, Hanna Seppänen, Caj Haglund, Risto Renkonen Tags: 7. Cystic lesions of the pancreas Source Type: research
The actual incidence of symptoms due to pancreatic cystic neoplasms: Are we overestimating a major indication for surgery? A prospective propensity matched cohort analysis
Objectives The prevalence of symptoms in pancreatic cystic neoplasms (PCNs) is mainly based on retrospective surgical series with consequent overestimation and uncertainty of their role in the decision-making. Aim of this study is to describe the actual prevalence of symptoms in PCNs without indication for surgery compared to a control group without PCNs. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Stefano Andrianello, Giovanni Marchegiani, Erica Secchettin, Giuseppe Malleo, Claudio Bassi, Roberto Salvia Tags: 7. Cystic lesions of the pancreas Source Type: research
Sonographic evaluation of cystic formations in pancreas
Objectives To improve the sonography evaluation of wall formation of pancreatic pseudocyst and differential diagnosis of the origin of cystic formations by comparing sonographic criteria with histology data from biopsy specimens obtained during surgery. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Oleksandr Babii, Boris Schevchenko, Iryna Konenko, Hanna Tuzko, Svetlana Ushchina Tags: 7. Cystic lesions of the pancreas Source Type: research
The role of age in pancreatic intraductal papillary neoplasms: same survival but different implications for the management
Objectives Little is known regarding the natural history of Intraductal Papillary Mucinous Neoplasms (IPMNs) of the pancreas diagnosed in younger individuals, as current guidelines do not specifically address this aspect. The aim of this study was to evaluate whether clinical features and malignancy risk of IPMNs are influenced by patient's age at diagnosis. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Stefano Andrianello, Giovanni Marchegiani, Giampaolo Perri, Tommaso Pollini, Andrea Caravati, Erica Secchettin, Giuseppe Malleo, Claudio Bassi, Roberto Salvia Tags: 7. Cystic lesions of the pancreas Source Type: research
Pre-operative cytologic diagnosis of pancreatic cystic lesions: Value of molecular analysis
Objectives Cystic lesions of the pancreas comprise a wide spectrum of entities, ranging from non neoplastic lesions to benign and malignant neoplasms. The management of pancreatic cystic lesions, especially when based on imaging alone, often presents a challenge. Cytological diagnostics are increasingly performed, but results can be inconclusive. Various mutations are associated with pancreatic cystic neoplasms, e.g. GNAS, KRAS and VHL mutations. Thus, molecular analysis of cytologic samples could improve pre-operative diagnostics. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Lena Haeberle, Lisa Frohn, Wolfgang Goering, Nestor Ramirez, Martin Schramm, Natalia Pomjanski, Irene Esposito Tags: 7. Cystic lesions of the pancreas Source Type: research
Is main pancreatic duct dilation really an independent risk factor for malignancy in main-duct and combined-IPMNs?
Objectives In main duct (MD) or combined (CMD) IPMN pancreatic duct (MPD) diameter between 5-9 mm is identified by IAP guidelines as a worrisome feature (WF) requiring close follow up. Some authors argue that the risk of degeneration in these pts is already high enough to recommend surgery. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Francesca Aleotti, Stefano Crippa, Alessandra Piccioli, Enrico Longo, Francesca Di Salvo, Marco Schiavo Lena, Maria Chiara Petrone, Gianpaolo Balzano, Paolo Arcidiacono, Corrado Rubini, Giuseppe Zamboni, Claudio Doglioni, Massimo Falconi Tags: 7. Cystic lesions of the pancreas Source Type: research
Progression of pancreatic branch duct intraductal papillary mucinous neoplasm associates with cyst size
Objectives Most guidelines for managing patients with intraductal papillary mucinous neoplasms (IPMNs) vary considering proposed surveillance intervals and durations, usually determined based on expert opinions rather than substantial evidence. Studies on the progression and optimal surveillance intervals of branch duct IPMNs (BD-IPMN) are limited. Thus, we evaluated the progression of BD-IPMN at a single center and determined the optimal follow-up intervals and duration. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Jin-Young Jang Tags: 7. Cystic lesions of the pancreas Source Type: research
Peripoerative analysis and long term results of complications after surgical therapy of IPMN
Objectives Intraductal papillary mucinous neoplasms (IPMNs) are detected more frequently due to advanced medical imaging. IPMNs are considered to be premalignant lesions with different rates of malignant transformation dependent on histological characteristics and localization. Malignancy rate in IPMNs with high-risk stigmata is up to 62%. Although premalignant lesions, the risk of operation is high. Therefore, the risk of a malignant transformation must be balanced with the perioperative risks and with the quality of life of patients. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Caterina Chiminazzo, Emrullah Birgin, Andrea Rech, Christoph Reissfelder, Felix R ückert Tags: 7. Cystic lesions of the pancreas Source Type: research
Pancreatic cystic lesions in diabetes mellitus patients
Objectives According to literature and previous data from our department, exocrine pancreatic insufficiency is relatively common among patients with diabetes mellitus (DM). Marked alterations in the exocrine pancreas are observed in patients with DM, including changes in size, morphology, and histology. Atrophy of the gland and acini, lymphocytic infiltration, moderate to severe fibrosis, and fatty changes are usually noted. Pseudocysts are the most common cystic lesions and may be formed in the setting of acute or chronic pancreatitis. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Michal Lipinski, Martyna Rozek, Marta Sznurkowska, Ewa Jozefik, Malgorzata Degowska, Grazyna Rydzewska Tags: 7. Cystic lesions of the pancreas Source Type: research
Reappraisal of main pancreatic duct in IPMN under surveillance: dilatation alone is not an absolute indication for surgery
Objectives The correlation between the risk of pancreatic cancer (PC) and a dilated main pancreatic duct (MPD) in IPMNs is a matter of debate. The aim of this study was to assess the role of MPD size in predicting PC in a large cohort of both resected and surveilled IPMNs. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Stefano Andrianello, Giovanni Marchegiani, Giorgia Morbin, Erica Secchettin, Mirko D'Onofrio, Riccardo De Robertis, Giuseppe Malleo, Claudio Bassi, Roberto Salvia Tags: 7. Cystic lesions of the pancreas Source Type: research
Diagnosis and treatment of solid-pseudopapillary tumors of the pancreas: a single institution experience with 97 cases
Objectives To evaluate diagnosis and surgical management of solid pseudopapillary tumors of the pancreas (SPTP) in a single center setting. (Source: Pancreatology)
Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Jishu Wei, Peng Wang, Junli Wu, Wenbin Xu, Qiuyang Chen, Wentao Gao, Kuirong Jiang, Yi Miao Tags: 7. Cystic lesions of the pancreas Source Type: research
