Development and Evaluation of a Nomogram to Predict the Eventual Severity of the First Episode of Acute Pancreatitis
Conclusions
This nomogram may be an effective clinical tool for predicting the first episode of SAP. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Blood Purification for Hypertriglyceridemia-Induced Acute Pancreatitis: A Meta-analysis
Conclusions
In the treatment of hypertriglyceridemia-induced acute pancreatitis, BP methods are effective in accelerating triglyceride level reduction and shortening hospital stay but do not affect the efficacy or reduce mortality significantly compared with conventional treatment. Insulin therapy has the same effect as BP but decreases incidence of complications and cost. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
The Association Between Opioid Use and Opioid Type and the Clinical Course and Outcomes of Acute Pancreatitis
Conclusions
Mortality among acute pancreatitis patients did not differ significantly between patients receiving morphine, nonmorphine opioids, and nonopioids. However, morphine treatment was associated with higher rates of some serious adverse events. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Treatment and Prevention of Intraabdominal Bleeding in Necrotizing Pancreatitis Patients Treated With a Step-Up Approach
Conclusions
Bleeding events in NP patients treated with a MIS approach are associated with a 6-fold increase in mortality. Endovascular intervention is an effective strategy for the management of bleeding events. Prophylactic embolization may be an effective technique for reducing bleeding complications. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Benefit From Nonsurgical Treatment for Asymptomatic Pancreatolithiasis
Conclusions
Nonsurgical treatment in asymptomatic pancreatolithiasis may preserve pancreatic exocrine function as well as in symptomatic pancreatolithiasis. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Prognostic Analysis of Distal Pancreatectomy for Pancreatic Body and/or Tail Cancer Involving the Portal Vein: Is Pancreatic Body and/or Tail Cancer Involving the Portal Vein Resectable?
Conclusions
Pancreatic body and/or tail cancer contact with PV ≤180° should be considered borderline resectable because of poor survival. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Risk Factors for Delayed Gastric Emptying After Pancreaticoduodenectomy
Conclusions
We demonstrated that implementation of the preoperative stent, pylorus resection, and diabetes mellitus are independent risk factors for DGE. Pylorus preservation should remain the standard of care in PD. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Phase I Trial of nab-Paclitaxel Administered Concurrently With Radiotherapy in Patients With Locally Advanced Inoperable Pancreatic Adenocarcinoma
Conclusions
Nab-paclitaxel and EBRT was well-tolerated at doses below 100 mg/m2. The MTD and recommended phase II study dose for nab-paclitaxel with EBRT is 75 mg/m2 in this disease. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Comparing Outcomes and Cost Between Pancreas Transplant and Standard of Care in Patients With Type 1 Diabetes
Conclusions
Although there is no difference in survival for PTA compared with standard of care, PTA is a cost-saving therapy for type 1 diabetes. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
FGFR3 Nuclear Translocation Contributes to Proliferative Potential and Poor Prognosis in Pancreatic Ductal Adenocarcinoma
Conclusions
Our data showed that FGFR3 nuclear translocation contributes to cell proliferative potential and predicts poor long-term prognosis in PDAC after surgical resection. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Reduced Tripartite Motif-Containing Protein 29 Deteriorates the Severity of Severe Acute Pancreatitis
Conclusions
Our study demonstrated that TRIM29 negatively regulated the severity of SAP by degrading STING at its downstream, suggesting that TRIM29 and STING might serve as therapeutic targets for SAP. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Chemical Exchange Saturation Transfer for Pancreatic Ductal Adenocarcinoma Evaluation
Objectives
The aims of the study are to evaluate the feasibility of using pH-sensitive magnetic resonance imaging, chemical exchange saturation transfer (CEST) in pancreatic imaging and to differentiate pancreatic ductal adenocarcinoma (PDAC) with the nontumor pancreas (upstream and downstream) and normal control pancreas.
Methods
Sixteen CEST images with PDAC and 12 CEST images with normal volunteers were acquired and magnetization transfer ratio with asymmetric analysis were measured in areas of PDAC, upstream, downstream, and normal control pancreas. One-way analysis of variance and receiver operating charact...
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Long-Term Follow-Up and Immunomonitoring of Relapsing Type 1 Autoimmune Pancreatitis Treated With Rituximab
Conclusions
Rituximab is an effective treatment for type 1 autoimmune pancreatitis that provides a rapid strong clinical, biological, and morphological response, which persists after discontinuation without any safety issues. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
The Landscape of Acute Pancreatitis Trials Registered in ClinicalTrials.gov: A Cross-sectional Study
Conclusions
Our results indicate that the research activity falls short of what is needed in terms of the burden of AP. The distribution of these AP-related studies by global regions indicates that there exists regional disparities. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
Urine Proteomics Reveals Sex-Specific Response to Total Pancreatectomy With Islet Autotransplantation
Conclusions
We found distinct changes in the urinary proteomic profile after TPIAT and the response to TPIAT is highly sex-specific. (Source: Pancreas)
Source: Pancreas - May 1, 2022 Category: Gastroenterology Tags: Original Articles Source Type: research
