Remote monitoring of implantable cardiac monitors in patients with unexplained syncope: Predictors of false ‐positive alert episodes
ConclusionPatients who have PVCs are at higher risk of inappropriate ICM activations. To reduce the occurrence of FP alerts, it may be beneficial to target a large R-wave amplitude during device insertion and avoid programming a low-frequency filter at 0.05  Hz. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 27, 2023 Category: Cardiology Authors: Vincenzo Russo, Simona Covino, Valentina De Pasquale, Erika Parente, Angelo Comune, Anna Rago, Andrea Antonio Papa, Ernesto Ammendola, Andrea Spadaro Guerra, Paola Napoli, Paolo Golino, Gerardo Nigro Tags: DEVICES Source Type: research

Systematic use of half normal saline during ablation of ventricular tachycardia in structural heart disease
ConclusionSystematic use of HNS during VT ablations in patients with structural heart disease leads to long-term recurrences rates and complications in the range of what is reported using normal saline. Although controlled studies are needed for demonstrating the superiority of such attitude, the use of HNS in every scar-related VT ablation seems safe for standard cases and may be furthermore useful in case of refractory arrhythmias due to difficult-to-ablate substrates. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 27, 2023 Category: Cardiology Authors: Miloud Cherbi, Quentin Voglimacci ‐Stephanopoli, Hubert Delasnerie, Franck Mandel, Guillaume Domain, Deborah Foltran, Pierre Mondoly, Maxime Beneyto, Anne Rollin, Philippe Maury Tags: ELECTROPHYSIOLOGY Source Type: research

The individual relationship between atrial fibrillation sources from CARTOFINDER mapping and atrial cardiomyopathy
ConclusionThe presence of ROIs from CF mapping was not directly associated with the extent and location of fibrosis. Further studies evaluating the relationship between focal and rotational activity and atrial cardiomyopathy are mandatory. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 27, 2023 Category: Cardiology Authors: Denise Guckel, Misagh Piran, Leonard Bergau, Mustapha El Hamriti, Thomas Fink, Vanessa Sciacca, Jan ‐Christian Reil, Martin Braun, Moneeb Khalaph, Guram Imnadze, Katharina Kramer, Sarah Friedrich, Jasmin Rühl, Hermann Körperich, Philipp Tags: ELECTROPHYSIOLOGY Source Type: research

Zero ‐fluoroscopy ablation with multielectrode pulse field ablation system: Case series
We report a first case series of three patients where a zero-fluoroscopy approach by intracardiac echocardiography was utilized and present a possible workflow for zero-fluoroscopy ablation with the Farapulse PFA system. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 27, 2023 Category: Cardiology Authors: Martin Rauber, Martin Manninger, Anna ‐Sophie Eberl, Daniel Scherr Tags: BRIEF COMMUNICATION Source Type: research

How likely is the sense ‐B‐noise to affect patients with subcutaneous implantable cardioverter‐defibrillators and can we solve that problem in every case?
ConclusionThe sense-B-noise affected 3% of patients in our cohort, with an incidence of 0.012 per patient-year of follow-up. Most patients potentially vulnerable to sense-B noise could be reprogrammed to the secondary sensing vector, if necessary. Further investigation of the sense-B-noise issue is needed. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 22, 2023 Category: Cardiology Authors: Szymon Budrejko, Agnieszka Zienciuk ‐Krajka, Szymon Olędzki, Ludmiła Daniłowicz‐Szymanowicz, Maciej Kempa Tags: DEVICES Source Type: research

Can phrenic nerve injury be anticipated by larger cryoballoons?
AbstractRecently, a novel size-adjustable cryoballoon has been introduced in clinical practice, which can be inflated to two different diameters (28 and 31  mm). The 31 mm cryoballoon is specifically designed to achieve better contact with remodeled pulmonary veins (PVs) that have wider ostia while avoiding deep cannulation, thereby potentially reducing the risk of phrenic nerve injury (PNI) associated with deep balloon cannulation. However, we encou ntered two cases of PNI during cryoballoon ablation using the novel system among our initial 25 consecutive case series. Herein, we present two cases that exhibited PNI duri...
Source: Pacing and Clinical Electrophysiology : PACE - October 21, 2023 Category: Cardiology Authors: Kentaro Goto, Shinsuke Miyazaki, Takuro Nishimura, Tomomasa Takamiya, Susumu Tao, Masateru Takigawa, Tetsuo Sasano Tags: BRIEF COMMUNICATION Source Type: research

Predictors of long ‐term survival in Japanese patients with heart failure with reduced ejection fraction (HFrEF) treated with cardiac resynchronization therapy‐defibrillators (CRT‐D)
ConclusionsIn Japanese CRT-D cases, lower NHYA class, preexisting mechanical dyssynchrony, and 1-year response to CRT predict long-term survival. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 21, 2023 Category: Cardiology Authors: Yuta Sakaguchi, Daisuke Izumi, Rhythm Wada, Rie Akagawa, Naomasa Suzuki, Takahiro Hakamata, Yasuhiro Ikami, Yuki Hasegaw, Sou Otsuki, Nobue Yagihara, Kenichi Iijima, Takayuki Inomata Tags: DEVICES Source Type: research

Superior approach from the pocket for atrioventricular junction ablation performed at the time of conduction system pacing implantation
ConclusionSimultaneous CSP and AVJA with SA is feasible, with a safety profile similar to FA. Compared to FA, this approach reduces the procedure times and allows earlier ambulation and discharge. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 21, 2023 Category: Cardiology Authors: Pietro Palmisano, Antonio Parlavecchio, Pasquale Crea, Alessandro Guido, Michele Accogli, Giovanni Coluccia Tags: ORIGINAL ARTICLE Source Type: research

High density mapping of complex atrial tachycardia in patients after cardiac surgery
This article showed the application of HDM technology in complex ATs from the mechanisms of complex ATs, the development of HDM technology, and the identification of scars or critical isthmus from HDM. HDM-guided approach is highly effective for identifying the ATs mechanism and critical isthmus. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 18, 2023 Category: Cardiology Authors: Lu Fu, Yumei Xue Tags: REVIEW Source Type: research

Mexiletine: Antiarrhythmic mechanisms, emerging clinical applications and mortality
AbstractMexiletine, a class Ib antiarrhythmic drug, exhibits its major antiarrhythmic effect via inhibition of the fast and late Na+ currents in myocardial tissues that are dependent on the opening of Na+ channels for their excitation. Through a comprehensive examination of mexiletine's therapeutic benefits and potential risks, we aim to provide valuable insights that reinforce its role as a vital therapeutic option for patients with ventricular arrhythmias, long QT syndrome, and other heart rhythm disorders. This review will highlight the current understandings of the antiarrhythmic effects and rationales for recent off-l...
Source: Pacing and Clinical Electrophysiology : PACE - October 17, 2023 Category: Cardiology Authors: Farah Olleik, Mohammed Hussein Kamareddine, Jenna Spears, Gary Tse, Tong Liu, Gan ‐Xin Yan Tags: REVIEW Source Type: research

Integrated machine learning a predictor of pacemaker implantation after transcatheter aortic valve replacement
(Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 17, 2023 Category: Cardiology Authors: Ignazio Condello, Giuseppe Nasso, Pasquale D'Alessandro, Gaetano Contegiacomo Tags: LETTER TO THE EDITOR Source Type: research

Pulmonary vein isolation by means of a novel cryoballoon technology in paroxysmal atrial fibrillation patients: 1 ‐year outcome from a large Italian multicenter clinical registry
ConclusionThe novel POLARx cryo-balloon system is safe and effective for PV isolation, displaying a 1-year freedom from atrial arrhythmia recurrence of 86.4%, which is in line to that reported with AFA-Pro CB or RF ablation.Clinical trial registrationCatheter Ablation of Arrhythmias with a High-Density Mapping System in Real-World Practice (CHARISMA). URL:http://clinicaltrials.gov/ Identifier: NCT03793998. Registration date: January 4, 2019. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 17, 2023 Category: Cardiology Authors: Stefano Bianchi, Antonio De Simone, Saverio Iacopino, Gaetano Fassini, Maurizio Malacrida, Pietro Rossi, Giuseppe Stabile, Andrea Petretta, Fabrizio Tundo, Filippo Maria Cauti, Sara Iuliano, Pasquale Filannino, Massimo Moltrasio, Michela Morl Tags: ELECTROPHYSIOLOGY Source Type: research

Nearly incessant supraventricular tachycardia in a child diagnosed without pacing maneuvers: What's the mechanism?
(Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 17, 2023 Category: Cardiology Authors: Giovanni Domenico Ciriello, Diego Colonna, Anna Correra, Emanuele Romeo, Maria Giovanna Russo, Berardo Sarubbi Tags: EP ROUNDS Source Type: research

The QRS frontal plane axis changes during left bundle branch block after transcatheter aortic valve replacement
ConclusionAlthough post TAVR-LBBB is associated with a leftward QRS axis shift in most patients, a non-negligible proportion of patients (27%) exhibited a rightward or no QRS axis shift. The latter group tend to have a higher risk of developing high degree AVB. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 14, 2023 Category: Cardiology Authors: Oren Yagel, Bernard Belhassen, David Planer, Offer Amir, Gabby Elbaz ‐Greener Tags: ELECTROPHYSIOLOGY Source Type: research

Low ‐energy defibrillation using a base–apex epicardial electrode
ConclusionPainless defibrillation using sheet-shaped electrodes on the epicardium is predicated on the basis of results using a heart simulator. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - October 13, 2023 Category: Cardiology Authors: Jun ‐ichi Okada, Takumi Washio, Seiryo Sugiura, Toshiaki Hisada Tags: DEVICES Source Type: research