Forthcoming Issues
Otolaryngologic Trauma (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - September 13, 2023 Category: ENT & OMF Source Type: research

Parathyroidectomy
This guide delineates a step-by-step approach to targeted parathyroidectomy and 4 gland exploration, with embedded clinical pearls regarding anatomy, approach, and considerations. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - September 13, 2023 Category: ENT & OMF Authors: Catherine Alessandra Colaianni, Maisie Shindo Source Type: research

Recurrent Laryngeal Nerve Monitoring
Intraoperative neuromonitoring (IONM) of the laryngeal nerves has become an important tool for neck endocrine surgery. In this article, the authors review the current evidence behind its use in neck endocrine procedures. The subtypes of IONM, including intermittent IONM,  continuous vagal IONM (vagal-CIONM), and laryngeal adductor reflex CIONM, will be discussed. Finally, the authors review recent advances in IONM, and how standardization of outcomes reporting will help minimise conjecture regarding the usefulness of IONM. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - September 6, 2023 Category: ENT & OMF Authors: Diana N. Kirke, Catherine F. Sinclair Source Type: research

Current and Novel Biologic Therapies for Patients with Asthma and Nasal Polyps
A substantial portion of asthma and nasal polyps (NPs) share a common pathogenesis, which includes type 2-mediated inflammation. Distinct endotypes and phenotypes characterizing asthma and chronic rhinosinusitis have been identified. With emerging evidence describing pathophysiology, novel targets for biologic monoclonal antibody treatments have been developed. There are currently six biologic therapies approved by the US Food and Drug Administration to treat asthma, including omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab, and tezepelumab, three of these —omalizumab, mepolizumab, and dupilumab—are also a...
Source: Otolaryngologic clinics of North America - September 6, 2023 Category: ENT & OMF Authors: Hanna K. Mandl, Jessa E. Miller, Daniel M. Beswick Source Type: research

Applications of Maxillomandibular Fixation, Occlusal Guidance, and Jaw Physiotherapy in the Management of Fractures of the Mandible
The goal of mandibular fracture management is to restore form and function. Maxillomandibular fixation, elastic occlusal guidance, and postoperative physiotherapy are essential elements to optimizing outcomes. Restoration of premorbid occlusion is paramount. Thus, an expert understanding of occlusion, coupled with the application of maxillomandibular techniques to achieve bony reduction with idealized dental occlusion, is required in the proper management of mandible fractures. Postoperatively, complete recovery initially requires elastic occlusal guidance followed by jaw range of motion physiotherapy. Bone healing, an ide...
Source: Otolaryngologic clinics of North America - August 31, 2023 Category: ENT & OMF Authors: Daniel J. Meara Source Type: research

Avoiding Complications of Thyroidectomy
Preservation of functional parathyroid glands during thyroidectomy and central neck surgery is crucial to avoid the common but serious complication of hypoparathyroidism. The first requirement is a solid foundational knowledge of anatomy and embryology which then enables the surgeon to use meticulous anticipatory dissection with identification and preservation of blood supply to the parathyroids. When preservation of blood supply is not possible, autotransplantation should be performed. New technologies harnessing the natural phenomenon of parathyroid autofluorescence to detect parathyroid tissue and indocyanine green to p...
Source: Otolaryngologic clinics of North America - August 31, 2023 Category: ENT & OMF Authors: Elizabeth E. Cottrill Source Type: research

Caring for the Patient with Otolaryngologic Trauma Is a Complex Matter
In an Austrian study of 14,654 patients with 35,129 injuries treated at a single Department of Cranio-Maxillofacial and Oral Surgery over a 15-year period, the following was seen.1 Older people were more prone to soft tissue lesions with a rising risk of 2.1% per year older, equal in men and women. Younger patients were at higher risk of dentoalveolar trauma with an increase of 4.4% per year younger, and this was 19.6% higher for women. The risk of sustaining facial bone fractures increased each year by 4.6% and was 66.4% times higher in men. A total of 2550 patients (17.4%) suffered 3834 concomitant injuries of other body...
Source: Otolaryngologic clinics of North America - August 31, 2023 Category: ENT & OMF Authors: Sujana S. Chandrasekhar Tags: Foreword Source Type: research

Surgical Management of Substernal Thyroid Goiters
This article discusses patient presentation, workup, and management options for patients with substernal goiter as well as surgical pearls to minimize risk of complications. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - August 29, 2023 Category: ENT & OMF Authors: Amanda J. Bastien, Allen S. Ho Source Type: research

Overview of Thyroid and Parathyroid Disease
The management of thyroid and parathyroid pathology varies widely, with unifying goals of symptomatic control and mitigating patient morbidity. In general, surgery is indicated when addressing malignancy or when medical management is insufficient. Over the last few decades, treatment paradigms for patients with head and neck endocrine disease have shifted significantly as our understanding of disease processes has expanded and with the advent of numerous relevant technologies. Here we provide a general overview of thyroid and parathyroid disease that may be managed by the otolaryngologist, with attention to emerging strate...
Source: Otolaryngologic clinics of North America - August 28, 2023 Category: ENT & OMF Authors: Raisa Tikhtman, David L. Steward Source Type: research

Thyroid and Parathyroid Surgery: No Longer “Horrid Butchery”
Over the last several decades otolaryngologists have become increasingly involved in the care of patients with thyroid and parathyroid diseases. Endocrine surgery has become a key component of residency training, a significant element of many otolaryngologists ’ practices, and the sole focus of some practitioners. This same period has also seen a significant evolution in the practice of endocrine surgery—with advances in surgical procedures, adjunct technologies, and approaches to minimizing surgical risks. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - August 26, 2023 Category: ENT & OMF Authors: Amy Y. Chen, Michael C. Singer Tags: Preface Source Type: research

Pearls of Parathyroidectomy
The treatment of hyperparathyroidism through parathyroidectomy requires careful and complete preoperative evaluation. There are multiple imaging modalities and methods available to clinicians today to aid in identifying a pathological lesion; however, each has limitations that the clinician must understand. A systematic approach to patient evaluation, imaging, and surgical exploration is necessary to ensure accurate diagnosis and maximize the chances of minimally invasive and successful surgical removal. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - August 25, 2023 Category: ENT & OMF Authors: Zoe H. Fullerton, Lisa A. Orloff Source Type: research

Overview of Thyroid and Parathyroid Disease —The Endocrinology Perspective
Thyroid and parathyroid disorders are quite common in the population and range from benign to malignant conditions that may be hormonally active or inactive. Select disorders of the thyroid and parathyroid can be managed medically, although there are a variety of circumstances that may require definitive management with surgery. Surgical intervention may be required for hormonal control, compressive symptoms, or for the removal and/or control of malignancy. The endocrinologist ’s perspective of the preoperative and postoperative management regarding thyroid and parathyroid surgeries will be discussed. (Source: Otolaryngo...
Source: Otolaryngologic clinics of North America - August 25, 2023 Category: ENT & OMF Authors: Maralee R. Kanin, Angela M. Leung Source Type: research

Secondary Hyperparathyroidism
Secondary hyperparathyroidism (SHPT) does not initiate as a primary dysfunction of parathyroid glands resulting from an intrinsic defect or disease but is the physiologic response of parathyroids to metabolic changes elsewhere in the body occurring over time. SHPT is a manifestation of a chronic condition that classically occurs from chronic kidney disease. In fact, given the relatively recent transition of populations from outside (agrarian) to indoor (industrial, information technology, and so forth) employment and a consequent reduction in sun exposure, combined with diets of highly processed food, vitamin D and calcium...
Source: Otolaryngologic clinics of North America - August 25, 2023 Category: ENT & OMF Authors: Brendan C. Stack Source Type: research

Autofluorescence of Parathyroid Glands
Postoperative hypoparathyroidism may cause significant patient morbidity and even mortality. Emerging technologies centered on autofluorescent properties of parathyroid glands when exposed to near-infrared light hold promise to improve surgical parathyroid gland identification and preservation. Two systems (probe-based and camera-based) are commercially available currently; however, neither system alone provides indication of vascular viability or postoperative parathyroid gland function. The administration of indocyanine green, when combined with near-infrared fluorescence imaging, enables subjective assessment of parathy...
Source: Otolaryngologic clinics of North America - August 25, 2023 Category: ENT & OMF Authors: Amanda Silver Karcioglu, Dana Hartl, David C. Shonka, Cristian M. Slough, Brendan C. Stack, Neil Tolley, Amr H. Abdelhamid Ahmed, Gregory W. Randolph Source Type: research

Surgery for Normocalcemic Hyperparathyroidism
Primary hyperparathyroidism is the most common cause of hypercalcemia, accounting for about 90% of all cases. This disorder is characterized by overactive parathyroid glands, leading to increased parathyroid hormone and excess serum calcium. (Source: Otolaryngologic clinics of North America)
Source: Otolaryngologic clinics of North America - August 25, 2023 Category: ENT & OMF Authors: Pallavi Kulkarni, David Goldenberg Source Type: research