Reply
We appreciate the correspondence by Steptoe et  al regarding our article describing the spectrum of eye disease,1 particularly the high rate of uveitis, associated with Ebola virus disease (EVD), which has been documented with a prevalence of 13% to 34%.1–3 Our experience in Liberia showed that 22% of patients presented with EVD-associated uv eitis, with 12 patients (57%) diagnosed with posterior uveitis based on detailed history and chorioretinal scarring patterns by ophthalmic examination.1 (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Jessica G. Shantha, Ian Crozier, Brent R. Hayek, Beau B. Bruce, John Fankhauser, Steven Yeh Tags: Correspondence Source Type: research

Re: Akagi et  al.: Rates of local retinal nerve fiber layer thinning before and after disc hemorrhage in glaucoma (Ophthalmology. 2017;124:1403-1411)
We read with great interest the article by Akagi et  al1 exploring the effects of disc hemorrhage (DH) on the progression of retinal nerve fiber layer (RNFL) thinning in glaucoma. They found that the rates of RNFL thinning were faster in DH quadrants after DH, and that intensification treatment has a beneficial effect.1 However, we have some questio ns. First, in this study, the authors found that the treatment intensification, visual field mean deviation, and difference in intraocular pressure before and after DH will have an effect on the global RNFL slope values. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Shida Chen Tags: Correspondence Source Type: research

Re: Chang et  al.: Accuracy of diagnostic imaging modalities for classifying pediatric eyes as papilledema versus pseudopapilledema (Ophthalmology. 2017;124:1839-1848)
We read with much interest the article by Chang et  al,1 which evaluated the accuracy of diagnostic imaging modalities for papilledema (PE) versus pseudopapilledema (PPE) in pediatric patients. We concur with our colleagues regarding the importance of reaching the correct diagnosis, given the potentially life-threatening consequences when PE is mis classified as PPE. We would, however, like to temper their statement that the best imaging technique rests with fluorescein angiography (FA). (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Augustin Lecler, Perrine Gillard Tags: Correspondence Source Type: research

Reply
We appreciate the opportunity to respond to Drs Lecler and Gillard, and thank them for their comments. As noted by Lecler and Gillard, the ultrasonographer in our study was a technician rather than an ophthalmologist or radiologist. However, our technician is dedicated only to performing B-scan ocular ultrasonography, performs dozens of these examinations weekly, and teaches ultrasonography technique to residents. Therefore, we have confidence in the ultrasonographic images he provided. We acknowledge that our ultrasonographic images were limited in that they were still images rather than videos, and a 20-MHz probe was not...
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Melinda Y. Chang, Federico G. Velez, Joseph L. Demer, Laura Bonelli, Peter A. Quiros, Anthony C. Arnold, Alfredo A. Sadun, Stacy L. Pineles Tags: Correspondence Source Type: research

Re: Pazos et  al.: Diagnostic accuracy of Spectralis SD OCT automated macular layers segmentation to discriminate normal from early glaucomatous eyes (Ophthalmology. 2017;124:1218-1228)
We read with great interest the report by Pazos et  al1 regarding the diagnostic performance of an automated macular layers segmentation algorithm to distinguish normal from early glaucomatous eyes. However, we believe that some discussion is needed. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Kunliang Qiu, Mingzhi Zhang Tags: Correspondence Source Type: research

Reply
We thank Dr Chen for taking an interest in our study,1 and for providing the opportunity to address these questions. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Tadamichi Akagi, Linda M. Zangwill, Robert N. Weinreb Tags: Correspondence Source Type: research

Reply
We appreciate the interest in our manuscript and the comments raised by the readers. The authors of the letter suggest that axial length and disc size differences between control and glaucoma subjects in our study, if they exist, are possible confounding factors regarding the discriminative ability of macular and peripapillary spectral-domain OCT parameters and may jeopardize the conclusions. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Marta Pazos, Agnieszka Dyrda, Marc Biarn és, Alfonso Antón Tags: Correspondence Source Type: research

West African Crystalline Maculopathy in a Nigerian Woman
A 56-year-old asymptomatic Nigerian woman with diabetes and no known family history of ocular disease presented for routine ocular examination and was found to have yellow highly-refractile crystals clustered in bilateral foveas (Fig 1A; left eye not shown, but similar in appearance). She had no exogenous risk factors for crystalline retinopathy, such as use of cathaxanthine or tamoxifen. OCT through crystals revealed hyperreflective foci (arrow) in the inner retinal layers (Fig 1B). These findings are consistent with a diagnosis of West African crystalline maculopathy, a condition first reported by Sarraf et  al (Sarraf ...
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Christina Y. Weng, Joseph F. Morales, Isha Gupta Tags: Pictures & Perspectives Source Type: research

Unilateral Double Optic Nerve Head Pits
Color fundus photograph of 2 temporal pits within the left optic nerve head of a healthy 29-year-old woman with 20/20 Snellen equivalent visual acuity and normal visual fields (Fig  1A). En face OCT angiography (AngioVue; Optovue) of the optic nerve demonstrating vascular flow within the pits (Fig 1B). Infrared photo (Fig 1C) of the optic nerve clearly defines the pits. The green line denotes the orientation of the scan shown in Figure 1D. High-resolution OCT line scan (Spec tralis; Heidelberg Engineering, Germany) through both pits (Fig 1D). (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Erin A. Boese, David Huang, Shandiz Tehrani Tags: Pictures & Perspectives Source Type: research

Fibrin Web in a Patient with Candida glabrata Endophthalmitis
A 60-year-old woman with Fuchs' dystrophy underwent an uncomplicated Descemet membrane endothelial keratoplasty. One week later, she developed culture-positive Candida glabrata endophthalmitis presumably due to a contaminated donor graft. The donor rim tissue culture also tested positive for Candida glabrata several days later. Despite multiple injections of intravitreal voriconazole, her vision declined to light perception and decision was made to proceed with pars plana vitrectomy. One day after surgery, a dense fibrin web was observed in the anterior chamber (Fig  1A). (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Christina Y. Weng, M. Bowes Hamill, Joseph F. Morales Tags: Pictures & Perspectives Source Type: research

Editorial Board
(Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Source Type: research

Contents
(Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Source Type: research

Corrigendum
The authors of “Sustained benefits of ranibizumab with or without laser in branch retinal vein occlusion” (2017;124(12):1778–1787) would like to issue the following correction to their article. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Tags: Corrigendum Source Type: research

Corrigendum
The authors of “Efficacy, safety, and risk factors for failure of standalone ab interno gelatin microstent implantation versus standalone trabeculectomy” (Ophthalmology. 2017;124(11):1579–1588) would like to issue the following correction to their article: (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Tags: Corrigendum Source Type: research

This Issue at a Glance
Newman-Casey et  al (p. 332) examined eye care providers' Medicare prescribing patterns for ophthalmic medications and estimate the potential cost savings to Medicare from generic or therapeutic drug substitutions and from negotiating drug prices. In a retrospective cross-sectional study, they analyzed the publicl y available Medicare Part D 2013 Prescriber Public Use File and the Summary file to calculate medication costs by physician specialty and drug. Eye care providers accounted for ∼2.3% of all Medicare Part D payments, or $2.4 billion. (Source: Ophthalmology)
Source: Ophthalmology - February 16, 2018 Category: Opthalmology Authors: Sandeep Ravindran Tags: This issue at a glance Source Type: research