This Issue at a Glance
Valsecchi et al (p. 210) evaluated the use of sunitinib as adjuvant therapy in a group of uveal melanoma patients with a high risk of developing distant metastases. They conducted a retrospective cohort study on uveal melanoma patients diagnosed from January 2007 to January 2013 and selected from the database of the Ocular Oncology Service at Wills Eye Hospital. The researchers compared the overall survival of 54 patients who received adjuvant sunitinib for 6 months to 74 patients in the control group with the same risk factors. (Source: Ophthalmology)
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Sandeep Ravindran Tags: This issue at a glance Source Type: research
A Simple Vista en Este N úmero
Valsecchi y otros (p. 210) evaluaron el uso de sunitinib, como terapia adyuvante, en un grupo de pacientes con melanoma uveal con alto riesgo de desarrollar met ástasis distante. Hicieron un estudio de cohorte retrospectivo en pacientes de melanoma uveal diagnosticados entre febrero de 2007 y enero de 2013 y seleccionados de la base de datos del Servicio de Oncología Ocular del Wills Eye Hospital. Los investigadores compararon la sobrevida global de 54 pa cientes que recibieron sunitinib como adyuvante administrado durante 6 meses a 74 pacientes en el grupo de control, con los mismos factores de riesgo. (Source: Ophthalmology)
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Sandeep Ravindran Tags: This issue at a glance Source Type: research
期刊一览
Valsecchi (p. 210) 等就舒尼替尼辅助治疗高危远端转移的葡萄膜黑色素瘤患者效果进行评估。研究者对2007年1月至2013年1月期间来自Wills眼科医院眼肿瘤专科数据库的葡萄膜黑色素瘤患者进行了回顾性队列研究。研究者对接受舒尼替尼辅助性治疗6个 月的54名患者及具有同等危险因素的74名对照组患者进行了总体生存对比。舒尼替尼组患者细胞遗传或分子特征更差,瘤体较小,且较为年轻。研究者分析表明,使用舒尼替尼作为辅助疗法与更长的存活期相关,在60岁以下患者中尤为显 著。...
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Sandeep Ravindran Tags: This issue at a glance Source Type: research
The African Descent and Glaucoma Evaluation Study (ADAGES) III
To describe the study protocol and baseline characteristics of the African Descent and Glaucoma Evaluation Study (ADAGES) III. (Source: Ophthalmology)
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Linda M. Zangwill, Radha Ayyagari, Jeffrey M. Liebmann, Christopher A. Girkin, Robert Feldman, Harvey Dubiner, Keri A. Dirkes, Matthew Holmann, Eunice Williams-Steppe, Naama Hammel, Luke J. Saunders, Suzanne Vega, Kevin Sandow, Kathryn Roll, Rigby Slight, Source Type: research
Genetic Risk Score Is Associated with Vertical Cup-to-Disc Ratio and Improves Prediction of Primary Open-Angle Glaucoma in Latinos
Genome-wide association studies have identified multiple genetic variants associated with vertical cup-to-disc ratio (VCDR). Genetic risk scores (GRS) examine the aggregate genetic effect of individual variants on a trait by combining these separate genetic variants into a single measure. The purpose of this study was to construct GRS for VCDR and to determine whether the GRS are associated with VCDR and whether the GRS increase the discriminatory ability for primary open-angle glaucoma (POAG) in a Latino population. (Source: Ophthalmology)
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Drew R. Nannini, Heejin Kim, Fangda Fan, Xiaoyi Gao Source Type: research
Gaze-Evoked Deformations in Optic Nerve Head Drusen
To determine if ocular ductions deform intrapapillary and peripapillary tissues in optic nerve head drusen (ONHD) and to compare these deformations with healthy eyes and eyes with other optic neuropathies. (Source: Ophthalmology)
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Patrick A. Sibony, Junchao Wei, Ian A. Sigal Tags: Original Article Source Type: research
Long-Term Outcomes of Total Exudative Retinal Detachments in Stage 3B Coats Disease
To evaluate the long-term outcomes of treatment of total exudative retinal detachments (ERDs) secondary to Coats disease (stage 3B) and the role of vitrectomy. (Source: Ophthalmology)
Source: Ophthalmology - January 18, 2018 Category: Opthalmology Authors: Albert S. Li, Antonio Capone, Michael T. Trese, Jonathan E. Sears, Andres Kychenthal, Irina De la Huerta, Philip J. Ferrone Tags: Original Article Source Type: research
Review of Ophthalmology Medical Professional Liability Claims in the United States from 2006 through 2015
To describe characteristics of closed medical professional liability (MPL) claims against ophthalmologists in the United States. (Source: Ophthalmology)
Source: Ophthalmology - January 15, 2018 Category: Opthalmology Authors: Atalie C. Thompson, P. Divya Parikh, Eleonora M. Lad Source Type: research
Iris Melanoma Outcomes Based on the American Joint Committee on Cancer Classification (Eighth Edition) in 432 Patients
This study evaluated outcomes of iris melanoma per the AJCC classification, eighth edition. (Source: Ophthalmology)
Source: Ophthalmology - January 15, 2018 Category: Opthalmology Authors: Carol L. Shields, Maura Di Nicola, Vladislav P. Bekerman, Swathi Kaliki, Carolina Alarcon, Enzo Fulco, Jerry A. Shields Tags: Original Article Source Type: research
Vitreoretinal Complications and Outcomes in 92 Eyes Undergoing Surgery for Modified Osteo-Odonto-Keratoprosthesis
To analyze vitreoretinal (VR) complications and treatment outcomes in eyes undergoing modified osteo-odonto-keratoprosthesis (OOKP) surgery. (Source: Ophthalmology)
Source: Ophthalmology - January 15, 2018 Category: Opthalmology Authors: Pukhraj Rishi, Ekta Rishi, Vishvesh Agarwal, Sridevi Nair, Geetha Iyer, Bhaskar Srinivasan, Shweta Agarwal Tags: Original Article Source Type: research
The 2016 American Academy of Ophthalmology IRIS ® Registry (Intelligent Research in Sight) Database
To describe the characteristics of the patient population included in the 2016 IRIS ® Registry (Intelligent Research in Sight) database for analytic aims. (Source: Ophthalmology)
Source: Ophthalmology - January 15, 2018 Category: Opthalmology Authors: Michael F. Chiang, Alfred Sommer, William L. Rich, Flora Lum, David W. Parke Tags: Original Article Source Type: research
Performance Rates Measured in the American Academy of Ophthalmology IRIS © Registry (Intelligent Research in Sight)
In 2007, the Centers for Medicare and Medicaid Systems (CMS) ushered in an era of performance measurement with its Physician Quality Reporting Initiative, later named the “Physician Quality Reporting System” (PQRS), a program that offered financial incentives to qualified providers to report quality measures to the CMS. In anticipation of the need for quality measures, the American Academy of Ophthalmology supported and worked with the American Medical Associatio n's Physician Consortium for Performance Improvement to convene the Eye Care Workgroup to develop performance measures on which providers could report. (Source: Ophthalmology)
Source: Ophthalmology - January 15, 2018 Category: Opthalmology Authors: William L. Rich, Michael F. Chiang, Flora Lum, Rebecca Hancock, David W. Parke Tags: Reports Source Type: research
The Real-World Effect of Intravitreous Anti –Vascular Endothelial Growth Factor Drugs on Intraocular Pressure
To identify sustained differences in intraocular pressure (IOP) after intravitreous injections of anti –vascular endothelial growth factor (VEGF) drugs. (Source: Ophthalmology)
Source: Ophthalmology - January 11, 2018 Category: Opthalmology Authors: Elizabeth A. Atchison, Kevin M. Wood, Cynthia G. Mattox, Catherine N. Barry, Flora Lum, Mathew W. MacCumber Source Type: research
Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion
To evaluate the effect of targeted retinal photocoagulation (TRP) on visual and anatomic outcomes and treatment burden in eyes with diabetic macular edema (DME). (Source: Ophthalmology)
Source: Ophthalmology - January 11, 2018 Category: Opthalmology Authors: David M. Brown, William C. Ou, Tien P. Wong, Rosa Y. Kim, Daniel E. Croft, Charles C. Wykoff, DAVE Study Group Tags: Original Article Source Type: research
Polypoidal Choroidal Vasculopathy
Polypoidal choroidal vasculopathy (PCV) is an age-related macular degeneration (AMD) subtype and is seen particularly in Asians. Previous studies have suggested disparity in response to intravitreal injections of anti –vascular endothelial growth factor (VEGF) agents between PCV and typical AMD, and thus, the preferred treatment for PCV has remained unclear. Recent research has provided novel insights into the pathogenesis of PCV, and imaging studies based on OCT suggest that PCV belongs to a spectrum of condit ions characterized by pachychoroid, in which disturbance in the choroidal circulation seems to be central to it...
Source: Ophthalmology - January 10, 2018 Category: Opthalmology Authors: Chui Ming Gemmy Cheung, Timothy Y.Y. Lai, Paisan Ruamviboonsuk, Shih-Jen Chen, Youxin Chen, K. Bailey Freund, Fomi Gomi, Adrian H. Koh, Won-Ki Lee, Tien Yin Wong Source Type: research
