Polymorphisms of Aldose Reductase (ALR2) Regulatory Gene are Risk Factors for Diabetic Retinopathy in Type-2 Diabetes Mellitus Patients in Bali, Indonesia.
Conclusion: It can be concluded that C(-104)T polymorphism in the regulatory region of Aldose Reductase (ALR2) gene was the risk factor for DR among T2DM patients in Bali, Indonesia. However, small sample size, systolic blood pressure, fasting blood glucose and 2-hours post-prandial blood glucose could affect our finding.
PMID: 30450144 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - November 20, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Refractive Error among Male Primary School Students in Jazan, Saudi Arabia: Prevalence and Associated Factors.
Conclusion: Refractive error was highly prevalent among primary school children in Jazan, Saudi Arabia. The rural students were more affected by refractive errors, mainly hyperopia. The preschool vision test should be reconsidered, and a periodic vision examination should be applied to detect vision problems as early as possible.
PMID: 30369991 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - October 31, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Maximising Refractive Outcomes with an Extended Depth of Focus IOL.
Conclusion: The Symfony IOL is an effective surgical means of addressing presbyopia and reducing postoperative spectacle dependence. We stress caution when offering potential spectacle independence for patients with over 1D of preoperative corneal astigmatism as these patients achieve statistically significantly inferior and less predictable visual results.
PMID: 30369992 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - October 31, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Outcomes of Wavefront-Optimized Laser-Assisted In-Situ Keratomileusis and Photorefractive Keratectomy for correction of Myopia and Myopic Astigmatism over One Year Follow-Up.
Conclusion: Our study results confirm the excellent efficacy, safety, good predictability and stability of myopia / myopic astigmatism correction by either wavefront- optimized LASIK or PRK over 1-year follow-up without significant differences between them using the WaveLight® EX500 excimer laser system.
PMID: 30294393 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - October 10, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Clinical Characteristics, Treatment Outcomes and Predictive Factors in Optic Neuritis.
Conclusion: NMOSD is a more common cause of optic neuritis than MS in Thai population. Female patients with poor initial VA, poor response to steroids treatment, and presenting recurrent attacks are highly suspicious for NMOSD. Optic neuritis without associated demyelinating disease has a better visual outcome and lower recurrence rate.
PMID: 30258505 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 28, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Simultaneous Accelerated Corneal Crosslinking and Laser In situ Keratomileusis for the Treatment of High Myopia in Asian Eyes.
Authors: Low JR, Lim L, Koh JCW, Chua DKP, Rosman M
PMID: 30197718 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 11, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
A New User-Friendly and Affordable Method in Descemet Stripping Endothelial Keratoplasty.
Conclusion: We proposed a novel effective user-friendly and affordable technique to perform DSAEK.
PMID: 30197719 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 11, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Development of In Vitro Methodologies to Investigate Binding by Sodium Hyaluronate in Eye Drops to Corneal Surfaces.
Conclusion: Dynamic and static models performed on different corneal sources were used to determine sodium hyaluronate binding kinetics in solutions under physiological conditions. These methodologies resulted in a ranking of the capacity of sodium hyaluronate to bind in vitro to corneal surfaces.
PMID: 30159097 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - September 1, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Anterior Segment Optical Coherence Tomography Analysis of Iris Morphometric Changes Induced by Prostaglandin Analogues Treatment in Patients with Primary Open Angle Glaucoma or Ocular Hypertension.
Conclusion: The present data indicate that PG treatment induced DMR thickness reduction and an increase in SMR thickness. These changes were not related to the duration of PG exposure.
PMID: 30123376 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Advances in Cornea.
Authors: Vanathi M
PMID: 30123377 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) Using Surgeon's Prepared Donor DM-Roll in Consecutive 100 Indian Eyes.
Conclusion: Descemet membrane endothelial keratoplasty is a safe and effective procedure in several types of endothelial diseases among Indian patients with encouraging surgical and visual outcomes. Complications are less and endothelial cell loss percentage is acceptable.
PMID: 30123378 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Simultaneous Accelerated Corneal Crosslinking and Laser In situ Keratomileusis for the Treatment of High Myopia in Asian Eyes.
Conclusion: LASIK Xtra achieved comparable safety, predictability and efficacy as LASIK in patients with high myopia. Good refractive stability was attained at 6-12 months. Further long term studies are required to determine whether simultaneous CXL is able to reduce postoperative LASIK keratectasia in high-risk individuals.
PMID: 30123379 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Perspective of Future Potent Therapies for Fuchs Endothelial Corneal Dystrophy.
Conclusions: This article reviews the current knowledge of the genetics and pathophysiology of FECD, and it introduces some potent therapeutic modalities that show promise as new treatments for this disorder.
PMID: 30123380 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Review of Corneal Biomechanical Properties Following LASIK and SMILE for Myopia and Myopic Astigmatism.
Authors: Damgaard IB, Reffat M, Hjortdal J
Abstract
Worldwide, femtosecond Laser Assisted In-situ Keratomileusis (LASIK) is a well known and commonly used refractive technique, although Small Incision Lenticule Extraction (SMILE) has become increasingly popular since it was introduced in 2011. In LASIK, a corneal flap is cut with a microkeratome or femtosecond laser, followed by thinning of the stromal bed with excimer laser ablation. In SMILE, a minor intrastromal lenticule is cut with a femtosecond laser and subsequently removed through a small incision, leaving the anterior and strongest part of the cor...
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
Use of Pressurized Air Infusion For Pre Descemet's Endothelial Keratoplasty (PDEK) - The Air Pump Assisted PDEK Technique.
Conclusions: This technique makes several steps of surgery easier and improves graft adhesion.
PMID: 30123382 [PubMed] (Source: Open Ophthalmology Journal)
Source: Open Ophthalmology Journal - August 22, 2018 Category: Opthalmology Tags: Open Ophthalmol J Source Type: research
