Rituximab Treatment of Hairy Cell Leukemia in a Patient with < b > < i > Mycobacterium kansasii < /i > < /b > Infection: A Case Report
Conclusion: Here, we demonstrate successful treatment of HCL with rituximab in a patient with concomitant disseminatedM. kansasii infection.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 21, 2021 Category: Cancer & Oncology Source Type: research
Effectiveness of Long-Term Treatment of Multiple Myeloma in Regular Care: Comparison of a Longitudinal and a Cross-Sectional Analysis Approach
Conclusion: Effectiveness of later therapy lines appears to be underestimated by cross-sectional analyses, and the conveyed focus on 1st-line treatment for multiple myeloma needs to be scrutinized.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 16, 2021 Category: Cancer & Oncology Source Type: research
Improving Chemotherapy-Induced Peripheral Neuropathy in Patients with Breast or Colon Cancer after End of (Neo)adjuvant Therapy: Results from the Observational Study STEFANO
Conclusion: OnLife ® treatment confirmed to be beneficial in reducing CIPN severity and in limiting the progression of neuropathy, more markedly in paclitaxel-treated patients and also in patients with oxaliplatin-induced CIPN.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 8, 2021 Category: Cancer & Oncology Source Type: research
Society Bulletins
Oncol Res Treat 2021;44:512 –520 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 6, 2021 Category: Cancer & Oncology Source Type: research
PharmaNews
Oncol Res Treat 2021;44:507 –511 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 6, 2021 Category: Cancer & Oncology Source Type: research
Inrebic ®: Neue Behandlungsoption bei Myelofibrose
Oncol Res Treat 2021;44:504 –506 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 6, 2021 Category: Cancer & Oncology Source Type: research
The Impact of Stereotactic or Whole Brain Radiotherapy on Neurocognitive Functioning in Adult Patients with Brain Metastases: A Systematic Review and Meta-Analysis
Conclusions: These findings suggest that after WBRT, patients can experience deterioration over a longer period of time. The cognitive side effects of SRS are transient. Therefore, this review advices to choose SRS as this will result in lowest risks for cognitive adverse side effects, irrespective of predicted survival. In an already cognitively vulnerable patient population with limited survival, this information can be used in communicating risks and aid in making educated decisions.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - September 3, 2021 Category: Cancer & Oncology Source Type: research
Development of Skin Rash Predicts Outcome of Anti-PD-1- and Anti-CTLA4-Based Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Cancer or Squamous Cell Carcinoma of the Head and Neck: A Single-Center Analysis
Conclusion: Development of immune-related skin rash was found to correlate with favorable outcome, suggesting its practical feasibility as a potential predictive surrogate marker.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 19, 2021 Category: Cancer & Oncology Source Type: research
A Phase 1 Study of a CDH6-Targeting Antibody-Drug Conjugate in Patients with Advanced Solid Tumors with Evaluation of Inflammatory and Neurological Adverse Events
Conclusions: Preclinical toxicology did not predict the neurotoxicity observed with HKT288, and a comprehensive assessment performed post hoc did not identify the mechanism of toxicity. The development of further CDH6-targeting ADCs should be pursued with caution.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 19, 2021 Category: Cancer & Oncology Source Type: research
An Unusual Case of Hypopituitarism as an Adverse Effect of Vandetanib and Remission of Breast Metastases in a Patient with Medullary Thyroid Cancer
Conclusion: To our knowledge, this is the first reported case of secondary adrenal insufficiency and hypogonadotropic hypogonadism related to therapy with vandetanib. Moreover, the prolonged PFS and the complete disappearance of some of the metastatic lesions in this patient are truly unusual.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 18, 2021 Category: Cancer & Oncology Source Type: research
Treatment Outcomes of Head and Neck Cancer Patients in the Elderly Receiving Different Chemoradiation Combinations: A Single-Center Experience
Conclusions: Management of LA HNSCC in the elderly is a challenging scenario. Our study shows that CRT is a feasible treatment modality for elderly patients with LA HNSCC. We recommend CRT with weekly cisplatin or weekly carboplatin and paclitaxel. A chemotherapy regimen should be carefully selected in this difficult to treat population.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 17, 2021 Category: Cancer & Oncology Source Type: research
Regulation of miR-126 and miR-122 Expression and Response of Imatinib Treatment on Its Expression in Chronic Myeloid Leukemia Patients
Conclusion: The study concludes that expression of miR-126 and miR-122 increases after imatinib treatment in CML patients and that miR-126 defines the good responders of imatinib therapy.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 16, 2021 Category: Cancer & Oncology Source Type: research
Neoadjuvant Therapy of Cyclin-Dependent Kinase 4/6 Inhibitors Combined with Endocrine Therapy in HR+/HER2 − Breast Cancer: A Systematic Review and Meta-Analysis
Conclusions: The results suggested that combination therapy had increased efficacy and toxicity compared to endocrine monotherapy and showed similar efficacy to and better safety than neoadjuvant chemotherapy.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 12, 2021 Category: Cancer & Oncology Source Type: research
Prognostic Value of Serum Apolipoprotein B to Apolipoprotein A-I Ratio in Hepatocellular Carcinoma Patients Treated with Transcatheter Arterial Chemoembolization: A Propensity Score-Matched Analysis
Conclusion: Serum ApoB/ApoA-I is a useful biomarker in predicting aggressive clinicopathological characteristics and poor prognosis in HCC patients treated with TACE.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 11, 2021 Category: Cancer & Oncology Source Type: research
Society Bulletins
Oncol Res Treat 2021;44:438 –442 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - August 3, 2021 Category: Cancer & Oncology Source Type: research