Radiofrequency Thermoablation and Hypofractionated Radiotherapy Combined Treatment for Bone Metastases: A Retrospective Study
Conclusion: The results of this retrospective analysis of patients treated with RFA-RT combined approach for BP support its safety and efficacy in terms of pain reduction. SBRT role in this combined approach has to be investigated in randomized trials.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 8, 2021 Category: Cancer & Oncology Source Type: research

PD-1 Blockade Elicits Ongoing Remission in Two Cases of Refractory Microsatellite-Stable Cancer Harboring a POLE Mutation
Conclusion: Colorectal cancer is a clinically and molecularly heterogenic disease which requires comprehensive genetic testing to screen for r are genetic alterations like POLE mutations to detect tumors harboring an ultramutator phenotype especially in patients that are refractory to standard chemotherapy. (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 7, 2021 Category: Cancer & Oncology Source Type: research

The Study of Cerebral Blood Flow Variations during Brain Metastases Radiotherapy
Conclusion: CBF changes can be feasibly assessed in different brain regions during RT based on 3D-ASL. The changes should be considered as a critical factor to determine the personal radiation dose for BMs, normal brain tissue, and peritumoral edema areas. (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 7, 2021 Category: Cancer & Oncology Source Type: research

The Study of Cerebral Blood Flow Variations during Brain Metastasis Radiotherapy
Purpose: To investigate the cerebral blood flow (CBF) variations during brain metastases (BMs) radiotherapy (RT) applying with MR 3D-arterial spin labeling (ASL). Materials and Methods: A total of 26 BMs patients with 54 tumors were retrospectively enrolled. MR examinations were performed before and during RT (30-50 Gy) with a total dose of 36-60 Gy (12-30 fractions) including contrast-enhanced T1-weighted, T2 Flair and 3D-ASL images. The relationship between CBF changes and the largest  cross-sectional area changes in BMs was investigated. And CBF changes in BMs, normal brain tissue, and peritumoral edema areas were ...
Source: Oncology Research and Treatment - December 7, 2021 Category: Cancer & Oncology Source Type: research

Sequence Therapy with FOLFIRINOX and Gemcitabine/Nab-Paclitaxel for Patients with Advanced Pancreatic Cancer – a Monocenter Retrospective Cohort Study
Background aims: While irresectable pancreatic cancer has still a dismal overall prognosis, evidence about the optimal chemotherapy sequence is scarce. After treatment with FOLFIRINOX in first-line, Gemcitabine-monotherapy was established for years. As a potential treatment alternative after failure of FOLFIRINOX therapy, combination of Gemcitabine and Nab-Paclitaxel is used. However, this combination has formally not yet been approved for second-line treatment and investigation of efficiency and treatment tolerance is the aim of this trial. Methods: Therefore, we investigated 225 patients with histologically confirmed lo...
Source: Oncology Research and Treatment - December 7, 2021 Category: Cancer & Oncology Source Type: research

Contents Vol. 44, 2021
Oncol Res Treat 2021;44:I –X (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

Acknowledgement to Reviewers
Oncol Res Treat 2021;44:719 –720 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

Society Bulletins
Oncol Res Treat 2021;44:737 –744 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

PharmaNews
Oncol Res Treat 2021;44:732 –736 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

PharmaNews
Oncol Res Treat 2021;44:730 –731 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

PharmaNews
Oncol Res Treat 2021;44:728 –729 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

PharmaNews
Oncol Res Treat 2021;44:727 –727 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

Effektive Erstlinien-Behandlung bei SCCHN mit Cetuximab-basierten Chemotherapie-Regimen
Oncol Res Treat 2021;44:721 –726 (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

OnkoImmun 15
Oncol Res Treat 2021;44:I –XII (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - December 3, 2021 Category: Cancer & Oncology Source Type: research

Comparative Analysis of Postoperative Complications after Cytoreductive Surgery and HIPEC in Gastric Cancer
Conclusion: CRS and HIPEC do not lead to an increased postoperative morbidity and mortality in AGC with PC. Albeit the poorer prognosis of patients with PC, survival of both groups was comparable.Oncol Res Treat (Source: Oncology Research and Treatment)
Source: Oncology Research and Treatment - November 29, 2021 Category: Cancer & Oncology Source Type: research