Drugs in Pregnancy: Optimizing Care for our Pregnant Patients
Welcome to the most recent issue of Obstetrics and Gynecology Clinics of North America entitled, “Drugs in Pregnancy.” Because pregnant people become sick and people with medical problems become pregnant, much of the care we provide to our pregnant patients involves the administration of drugs. Excluding vitamins and other supplements, a remarkable number of people take both prescribed and over-the-counter medications during their pregnancy. A cross-sectional, multinational, Web-based study,1 which surveyed 9459 pregnant people in 2011 to 2012, found that 81.2% respondents reported use of at least one prescribed or ove...
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Authors: Catherine S. Stika Tags: Preface Source Type: research
Drugs in Pregnancy: Common Use Despite Limited Information
Basic science and clinical investigations continue to provide new information pertaining to drug therapy for disorders encountered during pregnancy, whether unique or preexisting. This information is now incorporated in a new Obstetrics and Gynecology Clinics of North America issue, “Drugs in Pregnancy,” led by the Guest Editor, Catherine Stika, MD. (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Authors: William F. Rayburn Tags: Foreword Source Type: research
Celebrating the 50-year Anniversary of Obstetrics and Gynecology Clinics
It is my pleasure to recognize and reflect on the 50-year anniversary of the “birth” of the Obstetrics and Gynecology Clinics of North America by W.B. Saunders Company. Known to most physicians as simply “The Clinics,” our periodical remains an essential addition of the successful Clinics of North America publishing program. The series was acquired by Elsevier, the w orld’s largest medical publisher, which provided worldwide distribution to now more than 70 countries. For this reason, the title has changed to simply the Obstetrics and Gynecology Clinics. (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Authors: William F. Rayburn Tags: Introduction Source Type: research
Drugs in Pregnancy
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Authors: Catherine S. Stika Source Type: research
Copyright
Elsevier (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Source Type: research
Contributors
WILLIAM F. RAYBURN, MD, MBA (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Source Type: research
Contents
William F. Rayburn (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Source Type: research
Forthcoming Issues
Infectious Diseases in Obstetrics and Gynecology (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - February 22, 2023 Category: OBGYN Source Type: research
Safety and effectiveness of maternal COVID-19 vaccines among pregnant people and infants
Evidence has consistently demonstrated that COVID-19 mRNA vaccines are safe when given during pregnancy. COVID-19 mRNA vaccines protect pregnant people and their infants who are too young to receive COVID-19 vaccines. While generally protective, monovalent vaccine effectiveness was lower during SARS-CoV-2 Omicron variant predominance, in part due to changes in the Omicron spike protein. Bivalent vaccines, that combine ancestral strain and Omicron variant, may improve protection against Omicron variants. Everyone, including pregnant people, should stay up to date with recommended COVID-19 vaccines and bivalent booster, when...
Source: Obstetrics and Gynecology Clinics - February 20, 2023 Category: OBGYN Authors: Katherine E. Fleming-Dutra, Lauren Head Zauche, Lauren E. Roper, Sascha R. Ellington, Christine K. Olson, Andrea J. Sharma, Kate R. Woodworth, Naomi Tepper, Fiona Havers, Sara E. Oliver, Evelyn Twentyman, Tara C. Jatlaoui Source Type: research
Maternal Mortality in Low and Middle-Income Countries
Despite a 38% decrease in global maternal mortality during the last decade, rates remain unacceptably high with greater than 800 maternal deaths occurring each day. There exists significant regional variation among rates and causes of maternal mortality, and the vast majority occurs in low-income and middle-income countries. The leading causes of direct maternal mortality are hemorrhage, hypertensive disorders of pregnancy, sepsis, complications of abortion, and thromboembolism. Eliminating preventable maternal mortality hinges on improving clinical management of these life-threatening obstetric conditions, as well as addr...
Source: Obstetrics and Gynecology Clinics - November 1, 2022 Category: OBGYN Authors: Emma R. Lawrence, Thomas J. Klein, Titus K. Beyuo Source Type: research
Human Immunodeficiency Virus Treatment and Prevention for Pregnant and Postpartum Women in Global Settings
Efforts to prevent mother-to-child transmission of human immunodeficiency virus (HIV) have led to dramatic reductions in pediatric HIV worldwide. New advances in HIV treatment and prevention, focused on pregnant and breastfeeding women living with HIV, have improved maternal health while decreasing vertical and horizontal HIV transmission. In this article, we describe how such interventions —including antiretroviral therapy and HIV pre-exposure prophylaxis—can be incorporated into antepartum and postpartum care in global settings. (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - November 1, 2022 Category: OBGYN Authors: Friday Saidi, Benjamin H. Chi Source Type: research
Global Preconception and Contraception Care
A life-course approach incorporating appropriate preconception and contraception care is key to achieving optimal maternal, neonatal, and child health outcomes. In low- and middle-income countries (LMIC), there is a large unmet need for contraception and an estimated 49% of pregnancies are unintended. In this article, we discuss preconception and contraception care in LMIC settings including key recommendations for content and service delivery. We discuss barriers and facilitators to contraceptive provision, discuss considerations for providers who may practice in LMIC settings, and highlight strategies for achieving incre...
Source: Obstetrics and Gynecology Clinics - November 1, 2022 Category: OBGYN Authors: Megan A. Cohen, Somesh Kumar, Mark Hathaway Source Type: research
Genital Tract Infections in Women, Pregnancy and Neonates
Treatable genital tract infections in women are common and most are transmitted via sexual contact with the potential for vertical transmission during pregnancy. Adverse infection outcomes include pelvic inflammatory disease, infertility, ectopic pregnancy, preterm delivery, and congenital or neonatal infection. Highly sensitive molecular diagnostic testing for genital tract infections is now recommended in many countries. Unfortunately, this testing is not yet widely available in low- and middle-income countries because of cost. Improved access to early diagnosis and treatment for curable genital tract infections is criti...
Source: Obstetrics and Gynecology Clinics - November 1, 2022 Category: OBGYN Authors: Alphonse N. Ngalame, Mwangelwa Mubiana-Mbewe, Jodie A. Dionne Source Type: research
Antenatal and Postnatal Care
Optimal care during the antenatal and postnatal phases of the life cycle is a potentially positive determinant of health elsewhere in the continuum. A successful transition from the antenatal to the postnatal period requires early detection, optimal management, and prevention of disease; health promotion; birth preparedness; and complication readiness. Women, their babies, and families need appropriate evidence-based care based on their dignity and human rights before, during, and after birth. In this review, we present an overview of the components of antenatal and postnatal care needed to provide women a culturally sensi...
Source: Obstetrics and Gynecology Clinics - November 1, 2022 Category: OBGYN Authors: Adeniyi Kolade Aderoba, Kwame Adu-Bonsaffoh Source Type: research
Pelvic Floor Disorders/Obstetric Fistula
This article focuses on epidemiology, risk factors, assessment, and treatment of PFD and OF in resource-poor settings. Adherence to basic medical ethics principles has to be maintained at all times, coupled with knowledge of and respect for local cultures, traditions, and perceptions of health norms. (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - November 1, 2022 Category: OBGYN Authors: Saifuddin T. Mama, Mohan Chandra Regmi Source Type: research
