Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" NeuroToxicology 83 (2021)  1-13
Neurotoxicology. 2023 Dec 23:S0161-813X(23)00185-7. doi: 10.1016/j.neuro.2023.12.014. Online ahead of print.NO ABSTRACTPMID:38143152 | DOI:10.1016/j.neuro.2023.12.014 (Source: Neurotoxicology)
Source: Neurotoxicology - December 24, 2023 Category: Neurology Authors: Giulia Costa Stefan Spulber Elena Paci Maria Antonietta Casu Sandra Ceccatelli Nicola Simola Micaela Morelli Source Type: research

Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" NeuroToxicology 83 (2021)  1-13
Neurotoxicology. 2023 Dec 23:S0161-813X(23)00185-7. doi: 10.1016/j.neuro.2023.12.014. Online ahead of print.NO ABSTRACTPMID:38143152 | DOI:10.1016/j.neuro.2023.12.014 (Source: Neurotoxicology)
Source: Neurotoxicology - December 24, 2023 Category: Neurology Authors: Giulia Costa Stefan Spulber Elena Paci Maria Antonietta Casu Sandra Ceccatelli Nicola Simola Micaela Morelli Source Type: research

Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" NeuroToxicology 83 (2021)  1-13
Neurotoxicology. 2023 Dec 23:S0161-813X(23)00185-7. doi: 10.1016/j.neuro.2023.12.014. Online ahead of print.NO ABSTRACTPMID:38143152 | DOI:10.1016/j.neuro.2023.12.014 (Source: Neurotoxicology)
Source: Neurotoxicology - December 24, 2023 Category: Neurology Authors: Giulia Costa Stefan Spulber Elena Paci Maria Antonietta Casu Sandra Ceccatelli Nicola Simola Micaela Morelli Source Type: research

The role of carbon monoxide in aerotoxic syndrome
Neurotoxicology. 2023 Dec 20:S0161-813X(23)00179-1. doi: 10.1016/j.neuro.2023.12.008. Online ahead of print.ABSTRACTChronic low-level exposure to toxic compounds in airplane cabin air may result in Aerotoxic Syndrome (AS). Aetiologic agents are organophosphates and numerous volatile organic hydrocarbons originating from leaks of engine oil and hydraulic fluids. Despite a documented history spanning decades, the role of carbon monoxide remains controversial. What evidence exists that carbon monoxide (CO), present in the cocktail of toxic compounds in bleed air, contributes to the AS? We selected 22 publications encompassing...
Source: Neurotoxicology - December 22, 2023 Category: Neurology Authors: G Hageman P van Broekhuizen J Nihom Source Type: research

Dietary Selenium and Mercury Intakes from Fish Consumption During Pregnancy: Seychelles Child Development Study Nutrition Cohort 2
Neurotoxicology. 2023 Dec 20:S0161-813X(23)00183-3. doi: 10.1016/j.neuro.2023.12.012. Online ahead of print.ABSTRACTSome health agencies have issued precautionary principle fish advisories to pregnant women based on the presence of methylmercury (MeHg) in fish that could possibly be harmful to the developing fetus. Fish, however, is a rich source of selenium (Se) and other nutrients essential for normal brain development. Selenium is also thought to have a key role in alleviating MeHg toxicity. We estimated the dietary Se and MeHg intakes and dietary Se:Hg molar ratios from the fish consumed in a high fish-eating pregnant ...
Source: Neurotoxicology - December 22, 2023 Category: Neurology Authors: Maria Wesolowska Alison J Yeates Emeir M McSorley Gene E Watson Edwin van Wijngaarden Nathalie Bodin Rodney Govinden Juddy Jean-Baptiste Stephanie Desnousse Conrad F Shamlaye Gary J Myers J J Strain Maria S Mulhern Source Type: research

Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" [NeuroToxicology, 83 (2021),  1-13]
Neurotoxicology. 2023 Dec 21:S0161-813X(23)00181-X. doi: 10.1016/j.neuro.2023.12.010. Online ahead of print.NO ABSTRACTPMID:38135581 | DOI:10.1016/j.neuro.2023.12.010 (Source: Neurotoxicology)
Source: Neurotoxicology - December 22, 2023 Category: Neurology Authors: Giulia Costa Stefan Spulber Elena Paci Maria Antonietta Casu Sandra Ceccatelli Nicola Simola Micaela Morelli Source Type: research

The role of carbon monoxide in aerotoxic syndrome
Neurotoxicology. 2023 Dec 20:S0161-813X(23)00179-1. doi: 10.1016/j.neuro.2023.12.008. Online ahead of print.ABSTRACTChronic low-level exposure to toxic compounds in airplane cabin air may result in Aerotoxic Syndrome (AS). Aetiologic agents are organophosphates and numerous volatile organic hydrocarbons originating from leaks of engine oil and hydraulic fluids. Despite a documented history spanning decades, the role of carbon monoxide remains controversial. What evidence exists that carbon monoxide (CO), present in the cocktail of toxic compounds in bleed air, contributes to the AS? We selected 22 publications encompassing...
Source: Neurotoxicology - December 22, 2023 Category: Neurology Authors: G Hageman P van Broekhuizen J Nihom Source Type: research

Dietary Selenium and Mercury Intakes from Fish Consumption During Pregnancy: Seychelles Child Development Study Nutrition Cohort 2
Neurotoxicology. 2023 Dec 20:S0161-813X(23)00183-3. doi: 10.1016/j.neuro.2023.12.012. Online ahead of print.ABSTRACTSome health agencies have issued precautionary principle fish advisories to pregnant women based on the presence of methylmercury (MeHg) in fish that could possibly be harmful to the developing fetus. Fish, however, is a rich source of selenium (Se) and other nutrients essential for normal brain development. Selenium is also thought to have a key role in alleviating MeHg toxicity. We estimated the dietary Se and MeHg intakes and dietary Se:Hg molar ratios from the fish consumed in a high fish-eating pregnant ...
Source: Neurotoxicology - December 22, 2023 Category: Neurology Authors: Maria Wesolowska Alison J Yeates Emeir M McSorley Gene E Watson Edwin van Wijngaarden Nathalie Bodin Rodney Govinden Juddy Jean-Baptiste Stephanie Desnousse Conrad F Shamlaye Gary J Myers J J Strain Maria S Mulhern Source Type: research

Corrigendum to "In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice" [NeuroToxicology, 83 (2021),  1-13]
Neurotoxicology. 2023 Dec 21:S0161-813X(23)00181-X. doi: 10.1016/j.neuro.2023.12.010. Online ahead of print.NO ABSTRACTPMID:38135581 | DOI:10.1016/j.neuro.2023.12.010 (Source: Neurotoxicology)
Source: Neurotoxicology - December 22, 2023 Category: Neurology Authors: Giulia Costa Stefan Spulber Elena Paci Maria Antonietta Casu Sandra Ceccatelli Nicola Simola Micaela Morelli Source Type: research

Synchrotron speciation of umbilical cord mercury and selenium after environmental exposure in Niigata
Neurotoxicology. 2023 Dec 19:S0161-813X(23)00182-1. doi: 10.1016/j.neuro.2023.12.011. Online ahead of print.ABSTRACTThe insidious and deadly nature of mercury's organometallic compounds is informed by two large scale poisonings due to industrial mercury pollution that occurred decades ago in Minamata and Niigata, Japan. The present study examined chemical speciation for both mercury and selenium in a historic umbilical cord sample from a child born to a mother who lived near the Agano River in Niigata. The mother had experienced mercury exposure leading to more than 50 ppm mercury measured in her hair and was symptomatic 9...
Source: Neurotoxicology - December 21, 2023 Category: Neurology Authors: Monica Weng Natalia V Dolgova Linda I Vogt Muhammad Qureshi Dimosthenis Sokaras Thomas Kroll Hisashi Sait ō John L O'Donoghue Gene E Watson Gary J Myers Tomoko Sekikawa Ingrid J Pickering Graham N George Source Type: research

Synchrotron speciation of umbilical cord mercury and selenium after environmental exposure in Niigata
Neurotoxicology. 2023 Dec 19:S0161-813X(23)00182-1. doi: 10.1016/j.neuro.2023.12.011. Online ahead of print.ABSTRACTThe insidious and deadly nature of mercury's organometallic compounds is informed by two large scale poisonings due to industrial mercury pollution that occurred decades ago in Minamata and Niigata, Japan. The present study examined chemical speciation for both mercury and selenium in a historic umbilical cord sample from a child born to a mother who lived near the Agano River in Niigata. The mother had experienced mercury exposure leading to more than 50 ppm mercury measured in her hair and was symptomatic 9...
Source: Neurotoxicology - December 21, 2023 Category: Neurology Authors: Monica Weng Natalia V Dolgova Linda I Vogt Muhammad Qureshi Dimosthenis Sokaras Thomas Kroll Hisashi Sait ō John L O'Donoghue Gene E Watson Gary J Myers Tomoko Sekikawa Ingrid J Pickering Graham N George Source Type: research

Synchrotron speciation of umbilical cord mercury and selenium after environmental exposure in Niigata
Neurotoxicology. 2023 Dec 19:S0161-813X(23)00182-1. doi: 10.1016/j.neuro.2023.12.011. Online ahead of print.ABSTRACTThe insidious and deadly nature of mercury's organometallic compounds is informed by two large scale poisonings due to industrial mercury pollution that occurred decades ago in Minamata and Niigata, Japan. The present study examined chemical speciation for both mercury and selenium in a historic umbilical cord sample from a child born to a mother who lived near the Agano River in Niigata. The mother had experienced mercury exposure leading to more than 50 ppm mercury measured in her hair and was symptomatic 9...
Source: Neurotoxicology - December 21, 2023 Category: Neurology Authors: Monica Weng Natalia V Dolgova Linda I Vogt Muhammad Qureshi Dimosthenis Sokaras Thomas Kroll Hisashi Sait ō John L O'Donoghue Gene E Watson Gary J Myers Tomoko Sekikawa Ingrid J Pickering Graham N George Source Type: research

Cobalt-induced apoptosis of cochlear organotypic cultures and HEI-OC1 cells is mediated by Dicer
In this study, based on the clinical problem of cobalt ototoxicity, we first conducted an extensive search and collation of related theories, and on this basis, prepared an HEI-OC1 cell model and basilar membrane organotypic cultures after cobalt treatment. We used immunofluorescence staining, western blot, CCK8, and si-RNA to investigate the mechanism of cobalt ototoxicity, to discover its potential therapeutic targets. After comparing the reactive oxygen species, mitochondrial transmembrane potential, apoptosis-related protein expression, and cell viability of different treatment groups, the following conclusions were dr...
Source: Neurotoxicology - December 15, 2023 Category: Neurology Authors: Xuexin Lin Liling Li Jia Luo Dan Chen Jingqian Tan Peng Li Source Type: research

Cobalt-induced apoptosis of cochlear organotypic cultures and HEI-OC1 cells is mediated by Dicer
In this study, based on the clinical problem of cobalt ototoxicity, we first conducted an extensive search and collation of related theories, and on this basis, prepared an HEI-OC1 cell model and basilar membrane organotypic cultures after cobalt treatment. We used immunofluorescence staining, western blot, CCK8, and si-RNA to investigate the mechanism of cobalt ototoxicity, to discover its potential therapeutic targets. After comparing the reactive oxygen species, mitochondrial transmembrane potential, apoptosis-related protein expression, and cell viability of different treatment groups, the following conclusions were dr...
Source: Neurotoxicology - December 15, 2023 Category: Neurology Authors: Xuexin Lin Liling Li Jia Luo Dan Chen Jingqian Tan Peng Li Source Type: research

Cobalt-induced apoptosis of cochlear organotypic cultures and HEI-OC1 cells is mediated by Dicer
In this study, based on the clinical problem of cobalt ototoxicity, we first conducted an extensive search and collation of related theories, and on this basis, prepared an HEI-OC1 cell model and basilar membrane organotypic cultures after cobalt treatment. We used immunofluorescence staining, western blot, CCK8, and si-RNA to investigate the mechanism of cobalt ototoxicity, to discover its potential therapeutic targets. After comparing the reactive oxygen species, mitochondrial transmembrane potential, apoptosis-related protein expression, and cell viability of different treatment groups, the following conclusions were dr...
Source: Neurotoxicology - December 15, 2023 Category: Neurology Authors: Xuexin Lin Liling Li Jia Luo Dan Chen Jingqian Tan Peng Li Source Type: research