Associations between serum taurine concentrations in mothers and neonates and the children's anthropometrics and early neurodevelopment: Results from the Seychelles Child Development Study, Nutrition Cohort 2
CONCLUSION: The Seychellois population have high maternal and cord taurine concentrations owing to their high fish intake and may be considered taurine replete compared to individuals who consume a Westernised diet. This high taurine status may explain why there were no significant associations between maternal and cord taurine concentrations and outcomes after adjusting for covariates.PMID:37634816 | DOI:10.1016/j.neuro.2023.08.004 (Source: Neurotoxicology)
Source: Neurotoxicology - August 27, 2023 Category: Neurology Authors: Laura A Beggan Maria S Mulhern Hanne K M æhre Emeir M McSorley Alison J Yeates Alexis Zavez Sally W Thurston Conrad Shamlaye Edwin van Wijngaarden Philip W Davidson Gary J Myers J J Strain Edel O Elvevoll Source Type: research
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of С57Bl/6 mice
Neurotoxicology. 2023 Aug 18:S0161-813X(23)00104-3. doi: 10.1016/j.neuro.2023.08.002. Online ahead of print.ABSTRACTOverexposure to Mn causes a neurological disorder-manganism-with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the gene encoding for α3 isoform of Na+,K+-ATPase (NKA). The present study was designed to test the hypothesis that behavioral changes in the mouse model of manganism may be associated with changes in the expression and activity of α3 NKA in the cerebellum (CB) and striatum (STR)-the key brain structures responsible for motor control in adult mice. С57Bl/...
Source: Neurotoxicology - August 20, 2023 Category: Neurology Authors: Larisa V Smolyaninova Yulia A Timoshina Daniil S Berezhnoy Tatiana N Fedorova Ivan V Mikheev Irina F Seregina Nadezhda A Loginova Maxim G Dobretsov Source Type: research
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of С57Bl/6 mice
Neurotoxicology. 2023 Aug 18:S0161-813X(23)00104-3. doi: 10.1016/j.neuro.2023.08.002. Online ahead of print.ABSTRACTOverexposure to Mn causes a neurological disorder-manganism-with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the gene encoding for α3 isoform of Na+,K+-ATPase (NKA). The present study was designed to test the hypothesis that behavioral changes in the mouse model of manganism may be associated with changes in the expression and activity of α3 NKA in the cerebellum (CB) and striatum (STR)-the key brain structures responsible for motor control in adult mice. С57Bl/...
Source: Neurotoxicology - August 20, 2023 Category: Neurology Authors: Larisa V Smolyaninova Yulia A Timoshina Daniil S Berezhnoy Tatiana N Fedorova Ivan V Mikheev Irina F Seregina Nadezhda A Loginova Maxim G Dobretsov Source Type: research
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of С57Bl/6 mice
Neurotoxicology. 2023 Aug 18:S0161-813X(23)00104-3. doi: 10.1016/j.neuro.2023.08.002. Online ahead of print.ABSTRACTOverexposure to Mn causes a neurological disorder-manganism-with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the gene encoding for α3 isoform of Na+,K+-ATPase (NKA). The present study was designed to test the hypothesis that behavioral changes in the mouse model of manganism may be associated with changes in the expression and activity of α3 NKA in the cerebellum (CB) and striatum (STR)-the key brain structures responsible for motor control in adult mice. С57Bl/...
Source: Neurotoxicology - August 20, 2023 Category: Neurology Authors: Larisa V Smolyaninova Yulia A Timoshina Daniil S Berezhnoy Tatiana N Fedorova Ivan V Mikheev Irina F Seregina Nadezhda A Loginova Maxim G Dobretsov Source Type: research
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of С57Bl/6 mice
Neurotoxicology. 2023 Aug 18:S0161-813X(23)00104-3. doi: 10.1016/j.neuro.2023.08.002. Online ahead of print.ABSTRACTOverexposure to Mn causes a neurological disorder-manganism-with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the gene encoding for α3 isoform of Na+,K+-ATPase (NKA). The present study was designed to test the hypothesis that behavioral changes in the mouse model of manganism may be associated with changes in the expression and activity of α3 NKA in the cerebellum (CB) and striatum (STR)-the key brain structures responsible for motor control in adult mice. С57Bl/...
Source: Neurotoxicology - August 20, 2023 Category: Neurology Authors: Larisa V Smolyaninova Yulia A Timoshina Daniil S Berezhnoy Tatiana N Fedorova Ivan V Mikheev Irina F Seregina Nadezhda A Loginova Maxim G Dobretsov Source Type: research
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of С57Bl/6 mice
Neurotoxicology. 2023 Aug 18:S0161-813X(23)00104-3. doi: 10.1016/j.neuro.2023.08.002. Online ahead of print.ABSTRACTOverexposure to Mn causes a neurological disorder-manganism-with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the gene encoding for α3 isoform of Na+,K+-ATPase (NKA). The present study was designed to test the hypothesis that behavioral changes in the mouse model of manganism may be associated with changes in the expression and activity of α3 NKA in the cerebellum (CB) and striatum (STR)-the key brain structures responsible for motor control in adult mice. С57Bl/...
Source: Neurotoxicology - August 20, 2023 Category: Neurology Authors: Larisa V Smolyaninova Yulia A Timoshina Daniil S Berezhnoy Tatiana N Fedorova Ivan V Mikheev Irina F Seregina Nadezhda A Loginova Maxim G Dobretsov Source Type: research
Impact of manganese accumulation on Na,K-ATPase expression and function in the cerebellum and striatum of С57Bl/6 mice
Neurotoxicology. 2023 Aug 18:S0161-813X(23)00104-3. doi: 10.1016/j.neuro.2023.08.002. Online ahead of print.ABSTRACTOverexposure to Mn causes a neurological disorder-manganism-with motor symptoms that overlap closely with disorders associated with haploinsufficiency in the gene encoding for α3 isoform of Na+,K+-ATPase (NKA). The present study was designed to test the hypothesis that behavioral changes in the mouse model of manganism may be associated with changes in the expression and activity of α3 NKA in the cerebellum (CB) and striatum (STR)-the key brain structures responsible for motor control in adult mice. С57Bl/...
Source: Neurotoxicology - August 20, 2023 Category: Neurology Authors: Larisa V Smolyaninova Yulia A Timoshina Daniil S Berezhnoy Tatiana N Fedorova Ivan V Mikheev Irina F Seregina Nadezhda A Loginova Maxim G Dobretsov Source Type: research
Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5;98:61-85. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO-1, as well a...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5;98:61-85. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO-1, as well a...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5;98:61-85. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO-1, as well a...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5;98:61-85. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO-1, as well a...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-keto-beta boswellic acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5;98:61-85. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO-1, as well a...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-Keto-Beta Boswellic Acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5:S0161-813X(23)00103-1. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-Keto-Beta Boswellic Acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5:S0161-813X(23)00103-1. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
Acetyl-11-Keto-Beta Boswellic Acid(AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive disorder: Evidenced by CSF, blood plasma and histopathological alterations
Neurotoxicology. 2023 Aug 5:S0161-813X(23)00103-1. doi: 10.1016/j.neuro.2023.08.001. Online ahead of print.ABSTRACTObsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness characterised by obsessive thoughts and compulsive behaviours. Numerous factors can contribute to the development or progression of OCD. These factors may result from the dysregulation of multiple intrinsic cellular pathways, including SIRT-1, Nrf2, and HO-1. Inhibitors of selective serotonin reuptake (SSRIs) are effective first-line treatments for OCD. In our ongoing research, we have investigated the role of SIRT-1, Nrf2, and HO...
Source: Neurotoxicology - August 7, 2023 Category: Neurology Authors: Pranshul Sethi Sidharth Mehan Zuber Khan Swesha Chhabra Source Type: research
