Corrigendum to "Pharmacological evaluation of bromelain in mouse model of Alzheimer's disease" [NeuroToxicology 90 (2022) 19-34]
Neurotoxicology. 2023 Sep 20:S0161-813X(23)00109-2. doi: 10.1016/j.neuro.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37739906 | DOI:10.1016/j.neuro.2023.09.002 (Source: Neurotoxicology)
Source: Neurotoxicology - September 22, 2023 Category: Neurology Authors: Rakesh Kumar Rajan Kumar Neha Sharma Navneet Khurana Sachin Kumar Singh Saurabh Satija Meenu Mehta Manish Vyas Source Type: research

Corrigendum to "Pharmacological evaluation of bromelain in mouse model of Alzheimer's disease" [NeuroToxicology 90 (2022) 19-34]
Neurotoxicology. 2023 Sep 20:S0161-813X(23)00109-2. doi: 10.1016/j.neuro.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37739906 | DOI:10.1016/j.neuro.2023.09.002 (Source: Neurotoxicology)
Source: Neurotoxicology - September 22, 2023 Category: Neurology Authors: Rakesh Kumar Rajan Kumar Neha Sharma Navneet Khurana Sachin Kumar Singh Saurabh Satija Meenu Mehta Manish Vyas Source Type: research

Corrigendum to "Pharmacological evaluation of bromelain in mouse model of Alzheimer's disease" [NeuroToxicology 90 (2022) 19-34]
Neurotoxicology. 2023 Sep 20:S0161-813X(23)00109-2. doi: 10.1016/j.neuro.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37739906 | DOI:10.1016/j.neuro.2023.09.002 (Source: Neurotoxicology)
Source: Neurotoxicology - September 22, 2023 Category: Neurology Authors: Rakesh Kumar Rajan Kumar Neha Sharma Navneet Khurana Sachin Kumar Singh Saurabh Satija Meenu Mehta Manish Vyas Source Type: research

Corrigendum to "Pharmacological evaluation of bromelain in mouse model of Alzheimer's disease" [NeuroToxicology 90 (2022) 19-34]
Neurotoxicology. 2023 Sep 20:S0161-813X(23)00109-2. doi: 10.1016/j.neuro.2023.09.002. Online ahead of print.NO ABSTRACTPMID:37739906 | DOI:10.1016/j.neuro.2023.09.002 (Source: Neurotoxicology)
Source: Neurotoxicology - September 22, 2023 Category: Neurology Authors: Rakesh Kumar Rajan Kumar Neha Sharma Navneet Khurana Sachin Kumar Singh Saurabh Satija Meenu Mehta Manish Vyas Source Type: research

Linalool attenuates hypothalamus proteome disturbance facilitated by methamphetamine induced neurotoxicity in rats
Neurotoxicology. 2023 Sep 18;99:70-81. doi: 10.1016/j.neuro.2023.09.007. Online ahead of print.ABSTRACTBACKGROUND: One of the most powerful stimulants of the central nervous system is methamphetamine (METH). Linalool has a neuroprotective effect against ischemia injury by reducing oxidative stress and apoptosis. The present study investigated whether linalool can reverse the hypothalamus neurotoxicity and proteome disturbance in METH-treated rats.BRIEF METHOD: A total of 36 male albino rats were split into two equal groups (normal and METH-treated). Three equal subgroups of normal rats were created; Control, Linalool (25 m...
Source: Neurotoxicology - September 20, 2023 Category: Neurology Authors: Khaled M M Koriem Sara W B El-Qady Source Type: research

Linalool Attenuates Hypothalamus Proteome Disturbance Facilitated by Methamphetamine Induced Neurotoxicity in Rats
Neurotoxicology. 2023 Sep 18:S0161-813X(23)00123-7. doi: 10.1016/j.neuro.2023.09.007. Online ahead of print.ABSTRACTBACKGROUND: One of the most powerful stimulants of the central nervous system is methamphetamine (METH). Linalool has a neuroprotective effect against ischemia injury by reducing oxidative stress and apoptosis. The present study investigated whether linalool can reverse the hypothalamus neurotoxicity and proteome disturbance in METH-treated rats.BRIEF METHOD: A total of 36 male albino rats were split into two equal groups (normal and METH-treated). Three equal subgroups of normal rats were created; Control, L...
Source: Neurotoxicology - September 20, 2023 Category: Neurology Authors: Khaled M M Koriem Sara W B El-Qady Source Type: research

Linalool Attenuates Hypothalamus Proteome Disturbance Facilitated by Methamphetamine Induced Neurotoxicity in Rats
Neurotoxicology. 2023 Sep 18:S0161-813X(23)00123-7. doi: 10.1016/j.neuro.2023.09.007. Online ahead of print.ABSTRACTBACKGROUND: One of the most powerful stimulants of the central nervous system is methamphetamine (METH). Linalool has a neuroprotective effect against ischemia injury by reducing oxidative stress and apoptosis. The present study investigated whether linalool can reverse the hypothalamus neurotoxicity and proteome disturbance in METH-treated rats.BRIEF METHOD: A total of 36 male albino rats were split into two equal groups (normal and METH-treated). Three equal subgroups of normal rats were created; Control, L...
Source: Neurotoxicology - September 20, 2023 Category: Neurology Authors: Khaled M M Koriem Sara W B El-Qady Source Type: research

Mitophagy-dependent mitochondrial ROS mediates 2,5-hexanedione-induced NLRP3 inflammasome activation in BV2 microglia
In conclusion, our data indicated that HD triggered activation of NLRP3 inflammasome through mitophagy-dependent mtROS production, offering an important insight for the immunopathogenesis of environmental toxins-induced neuroinflammation and neurotoxicity.PMID:37722613 | DOI:10.1016/j.neuro.2023.09.008 (Source: Neurotoxicology)
Source: Neurotoxicology - September 18, 2023 Category: Neurology Authors: Wenqiong Wang Rui Chang Yan Wang Liyan Hou Qingshan Wang Source Type: research

Mitophagy-dependent mitochondrial ROS mediates 2,5-hexanedione-induced NLRP3 inflammasome activation in BV2 microglia
In conclusion, our data indicated that HD triggered activation of NLRP3 inflammasome through mitophagy-dependent mtROS production, offering an important insight for the immunopathogenesis of environmental toxins-induced neuroinflammation and neurotoxicity.PMID:37722613 | DOI:10.1016/j.neuro.2023.09.008 (Source: Neurotoxicology)
Source: Neurotoxicology - September 18, 2023 Category: Neurology Authors: Wenqiong Wang Rui Chang Yan Wang Liyan Hou Qingshan Wang Source Type: research

Iron chelation prevents nigrostriatal neurodegeneration in a chronic methamphetamine mice model
Neurotoxicology. 2023 Sep 15:S0161-813X(23)00122-5. doi: 10.1016/j.neuro.2023.09.006. Online ahead of print.ABSTRACTMethamphetamine (METH) has been established to selectively target and impair dopaminergic neurons through multiple pathways. Ferroptosis is a unique form of non-apoptotic cell death driven by cellular iron accumulation-induced lipid peroxidation. Nonetheless, it remains unclear whether METH can induce ferroptosis. In the present study, we sought to assess alterations in iron levels after chronic METH exposure and reveal the modulatory role of iron on METH-induced pathologies. Importantly, we demonstrated that...
Source: Neurotoxicology - September 17, 2023 Category: Neurology Authors: Shanshan Hu Xiaorong Huang Jian Huang Ying Qian Yingbiao Tian Ye Xiao Xiaolan Qi Xiaoxian Zhou Zhusheng Yang Zehui Chen Source Type: research

Iron chelation prevents nigrostriatal neurodegeneration in a chronic methamphetamine mice model
Neurotoxicology. 2023 Sep 15:S0161-813X(23)00122-5. doi: 10.1016/j.neuro.2023.09.006. Online ahead of print.ABSTRACTMethamphetamine (METH) has been established to selectively target and impair dopaminergic neurons through multiple pathways. Ferroptosis is a unique form of non-apoptotic cell death driven by cellular iron accumulation-induced lipid peroxidation. Nonetheless, it remains unclear whether METH can induce ferroptosis. In the present study, we sought to assess alterations in iron levels after chronic METH exposure and reveal the modulatory role of iron on METH-induced pathologies. Importantly, we demonstrated that...
Source: Neurotoxicology - September 17, 2023 Category: Neurology Authors: Shanshan Hu Xiaorong Huang Jian Huang Ying Qian Yingbiao Tian Ye Xiao Xiaolan Qi Xiaoxian Zhou Zhusheng Yang Zehui Chen Source Type: research

Corrigendum to "JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats" [Neurotoxicology 87 (2021) 70-85]
Neurotoxicology. 2023 Sep 10;99:10-13. doi: 10.1016/j.neuro.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37699281 | DOI:10.1016/j.neuro.2023.09.003 (Source: Neurotoxicology)
Source: Neurotoxicology - September 12, 2023 Category: Neurology Authors: Maylin Wong-Guerra Yanay Montano-Peguero Jeney Ram írez-Sánchez Javier Jim énez-Martin Luis Arturo Fonseca-Fonseca Daniela Hern ández-Enseñat Yasmine Nonose Odalys Vald és Abel Mondelo-Rodriguez Yaquelin Ortiz-Miranda Gretchen Bergado Tania Carmenat Source Type: research

Corrigendum to "JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats" [Neurotoxicology 87 (2021) 70-85]
Neurotoxicology. 2023 Sep 10;99:10-13. doi: 10.1016/j.neuro.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37699281 | DOI:10.1016/j.neuro.2023.09.003 (Source: Neurotoxicology)
Source: Neurotoxicology - September 12, 2023 Category: Neurology Authors: Maylin Wong-Guerra Yanay Montano-Peguero Jeney Ram írez-Sánchez Javier Jim énez-Martin Luis Arturo Fonseca-Fonseca Daniela Hern ández-Enseñat Yasmine Nonose Odalys Vald és Abel Mondelo-Rodriguez Yaquelin Ortiz-Miranda Gretchen Bergado Tania Carmenat Source Type: research

Corrigendum to "JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats" [Neurotoxicology 87 (2021) 70-85]
Neurotoxicology. 2023 Sep 10;99:10-13. doi: 10.1016/j.neuro.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37699281 | DOI:10.1016/j.neuro.2023.09.003 (Source: Neurotoxicology)
Source: Neurotoxicology - September 12, 2023 Category: Neurology Authors: Maylin Wong-Guerra Yanay Montano-Peguero Jeney Ram írez-Sánchez Javier Jim énez-Martin Luis Arturo Fonseca-Fonseca Daniela Hern ández-Enseñat Yasmine Nonose Odalys Vald és Abel Mondelo-Rodriguez Yaquelin Ortiz-Miranda Gretchen Bergado Tania Carmenat Source Type: research

Corrigendum to "JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats" [Neurotoxicology 87 (2021) 70-85]
Neurotoxicology. 2023 Sep 10;99:10-13. doi: 10.1016/j.neuro.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37699281 | DOI:10.1016/j.neuro.2023.09.003 (Source: Neurotoxicology)
Source: Neurotoxicology - September 12, 2023 Category: Neurology Authors: Maylin Wong-Guerra Yanay Montano-Peguero Jeney Ram írez-Sánchez Javier Jim énez-Martin Luis Arturo Fonseca-Fonseca Daniela Hern ández-Enseñat Yasmine Nonose Odalys Vald és Abel Mondelo-Rodriguez Yaquelin Ortiz-Miranda Gretchen Bergado Tania Carmenat Source Type: research