Understanding sources of adult age differences in task switching: Evidence from behavioral and ERP studies
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Patrick D. Gajewski, Nicola K. Ferdinand, Jutta Kray, Michael Falkenstein The task-switching paradigm is a valid tool to measure age-related changes in executive functions. It allows identifying the most vulnerable cognitive control processes affected by aging. This review provides an overview about the current evidence on behavioral and electrophysiological signatures of adult age differences in task switching with a focus on age-related changes in ERP correlates of three task-processing phases: (1) advanced task pr...
Source: Neuroscience and Biobehavioral Reviews - June 24, 2018 Category: Neuroscience Source Type: research

Episodic and working memory function in Primary Progressive Aphasia: A meta-analysis
Conclusions Memory deficits were more pronounced in lv-PPA compared to nfv-PPA. This suggests that memory tests may be helpful to distinguish between these PPA variants. (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - June 24, 2018 Category: Neuroscience Source Type: research

Cognitive benefits of angiotensin IV and angiotensin-(1 –7): A systematic review of experimental studies
Conclusion Studies of cognitive impairment show salutary effects of acute administration of Ang IV and its analogs, as well as AT4R activation. Brain RAS peptides appear most effective administered intracerebroventricularly, close to the time of learning acquisition or retention testing. Ang-(1–7) shows anti-dementia qualities. (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - June 23, 2018 Category: Neuroscience Source Type: research

How would publication bias distort the estimated effect size of prototypic antidepressants in the forced swim test?
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Ana B. Ramos-Hryb, Cari Harris, Omorose Aighewi, Cilene Lino-de-Oliveira This commentary aims to discuss the impact of publication bias on the estimated effect of prototypic antidepressants in the forced swim test (FST). A systematic review and meta-analysis (SRMA) recently reported by Kara et al. (2018) showed that selected prototypic antidepressants reduced immobility time of mice in the FST across a variety of experimental designs. Despite differences in the procedures for SRMA, these results resemble the interim ...
Source: Neuroscience and Biobehavioral Reviews - June 22, 2018 Category: Neuroscience Source Type: research

Feeling bad or feeling good, does emotion affect your consumption of food? A meta-analysis of the experimental evidence
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Catharine Evers, Alexandra Dingemans, Astrid F. Junghans, Anja Boevé Whether emotions affect eating, and in whom, has remained unclear. This meta-analysis assessed the effect of emotions on eating in both healthy and eating disordered individuals. Fifty-six experimental studies investigating the causal effect of emotions on eating behavior were selected including 3670 participants. Separate meta-analyses (random models) were performed for negative and positive emotions. Among healthy people the moderating impa...
Source: Neuroscience and Biobehavioral Reviews - June 22, 2018 Category: Neuroscience Source Type: research

Ventral anterior cingulate cortex and social decision-making
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Patricia L. Lockwood, Marco K. Wittmann Studies in the field of social neuroscience have recently made use of computational models of decision-making to provide new insights into how we learn about the self and others during social interactions. Importantly, these studies have increasingly drawn attention to brain areas outside of classical cortical "social brain" regions that may be critical for social processing. In particular, two portions of the ventral anterior cingulate cortex (vACC), subgenual anteri...
Source: Neuroscience and Biobehavioral Reviews - June 22, 2018 Category: Neuroscience Source Type: research

Gene x environment interactions in conduct disorder: Implications for future treatments
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): Nathalie E. Holz, Katrin Zohsel, Manfred Laucht, Tobias Banaschewski, Sarah Hohmann, Daniel Brandeis Conduct disorder (CD) causes high financial and social costs, not only in affected families but across society, with only moderately effective treatments so far. There is consensus that CD is likely caused by the convergence of many different factors, including genetic and adverse environmental factors. There is ample evidence of gene-environment interactions in the etiology of CD on a behavioral level regarding genetica...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

Aggressive behavior in transgenic animal models: A systematic review
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): Amanda Jager, Dorien A. Maas, Kim Fricke, Rob B. de Vries, Geert Poelmans, Jeffrey C. Glennon Aggressive behavior is often core or comorbid to psychiatric and neurodegenerative disorders. Transgenic animal models are commonly used to study the neurobiological mechanisms underlying aggressive phenotypes and have led to new insights into aggression. This systematic review critically evaluates the available literature on transgenic animal models tested for aggression with the resident-intruder test. By combining the availa...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

The impact of chronic stress during adolescence on the development of aggressive behavior: A systematic review on the role of the dopaminergic system in rodents
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): Jorim J Tielbeek, Zeineb Al-Itejawi, Josjan Zijlmans, Tinca JC Polderman, Joshua W Buckholtz, Arne Popma Pathological aggression, frequently observed in psychiatric patients and criminal subjects, poses a major burden on the health care and criminal justice system, necessitating better aetiological models to inform targets for prevention and intervention. Emerging evidence suggests that adverse experiences during development can cause long-lasting brain alterations associated with maladaptive behaviors, such as aggressi...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

The link between aberrant hypothalamic –pituitary–adrenal axis activity during development and the emergence of aggression—Animal studies
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): Sophie E. Walker, Aurélie Papilloud, Damien Huzard, Carmen Sandi Aggressive behavior is not uniform, including proactive and reactive forms of aggression. Aberrant functioning of the hypothalamic–pituitary–adrenal (HPA) axis is frequently associated with abnormal aggression. Here, we review the rodent literature in order to assess whether developmental abnormalities in the HPA axis can be causally linked with the emergence of abnormal aggression. We examine studies that involve genetic models and life...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

Preclinical models of conduct disorder – principles and pharmacologic perspectives
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): Jozsef Haller The translational value of preclinical research was recently enhanced by abnormal aggression models, which focus on deviant behaviors induced by the exposure of rodents to etiological factors of aggression-related psychopathologies. Prompted by similar trials in other psychiatric disorders, here we investigate models of abnormal aggression from the perspective of DSM5 criteria. After proposing principles based on which analogies can be established between psychopathology symptoms and rodent behavioral dysf...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

Neuro-cognitive system dysfunction and symptom sets: A review of fMRI studies in youth with conduct problems
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): R.J.R. Blair, K. Veroude, J.K. Buitelaar In this paper, we review fMRI work on neuro-cognitive systems that are considered to be dysfunctional in individuals with conduct problems (i.e., individuals with Conduct Disorder (CD), Oppositional Defiant Disorder (ODD) or antisocial behavior without formal clinical diagnosis). These are: empathy, the acute threat response, reinforcement-based decision-making, response inhibition and the Default Mode Network. Evidence regarding the Default Mode Network is somewhat inconsistent ...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

Clock genes, ADHD and aggression
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 Author(s): Floriana Mogavero, Amanda Jager, Jeffrey C. Glennon Attention deficit/hyperactivity disorder (ADHD) is frequently associated with comorbid aggression and sleep disturbances. The sleep/wake cycle is under the control of the circadian system which is moderated by clock genes. Clock genes can regulate the transcription of monoamine oxidase A, which is involved in the degradation of monoamines. Disturbances in monoamine interaction with clock genes in those with monoamine gene polymorphisms may regulate susceptibility of AD...
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

Editorial: Jeffrey Glennon & amp; Simone Macr ì
Publication date: August 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 91 (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - June 14, 2018 Category: Neuroscience Source Type: research

Common social cognitive impairments do not mean common causes: A commentary on Cotter et al. (2018)
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): David Dodell-Feder, Laura T. Germine Many clinical conditions, ranging from psychiatric to neurodegenerative illnesses, are associated with impairments in the processes by which we perceive, interpret, and respond to social information; a suite of abilities known as social cognition. Through a systematic review of meta-analyses, Cotter et al. (2018) present a compelling view of social cognitive deficits as a core phenotype of many clinical conditions. However, we caution against one potential interpretation of their ...
Source: Neuroscience and Biobehavioral Reviews - June 11, 2018 Category: Neuroscience Source Type: research

Understanding individual variability in symptoms and recovery following mTBI: A role for TMS-EEG?
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Hannah L. Coyle, Jennie Ponsford, Kate E. Hoy The pathophysiology associated with mild traumatic brain injury (mTBI) includes neurometabolic and cytoskeletal changes that have been shown to impair structural and functional connectivity. Evidence that persistent neuropsychological impairments post injury are linked to structural and functional connectivity changes is increasing. However, to date the relationship between connectivity changes, heterogeneity of persistent symptoms and recovery post mTBI has been poorly c...
Source: Neuroscience and Biobehavioral Reviews - June 11, 2018 Category: Neuroscience Source Type: research

Clinical use of semantic space models in psychiatry and neurology: A systematic review and meta-analysis
Publication date: Available online 8 June 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): J.N. de Boer, A.E. Voppel, M.J.H. Begemann, H.G. Schnack, F. Wijnen, I.E.C. Sommer Verbal communication disorders are a hallmark of many neurological and psychiatric illnesses. Recent developments in computational analysis provide objective characterizations of these language abnormalities. We conducted a meta-analysis assessing semantic space models as a diagnostic or prognostic tool in psychiatric or neurological disorders. Diagnostic test accuracy analyses revealed reasonable sensitivity and specificity and hig...
Source: Neuroscience and Biobehavioral Reviews - June 9, 2018 Category: Neuroscience Source Type: research

Amygdala where art thou?
Publication date: Available online 7 June 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Miquel A. Fullana, Anton Albajes-Eizagirre, Carles Soriano-Mas, Bram Vervliet, Narcís Cardoner, Olívia Benet, Joaquim Radua, Ben J. Harrison (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - June 8, 2018 Category: Neuroscience Source Type: research

A mind full of self: Self-referential processing as a mechanism underlying the therapeutic effects of mindfulness training on internalizing disorders
Publication date: Available online 8 June 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Yanli Lin, Courtney P. Callahan, Jason S. Moser The aim of the current review is to advance the hypothesis that change in self-referential processing is a key but under-examined mechanism through which mindfulness training confers its therapeutic benefits for individuals with internalizing disorders. Consequently, we integrated neuroscientific studies on aberrant self-referential processing in internalizing disorders with contemplative science scholarship examining the effects of mindfulness training on the self-r...
Source: Neuroscience and Biobehavioral Reviews - June 8, 2018 Category: Neuroscience Source Type: research

Neuroimaging perspectives on fetal motor behavior
Publication date: Available online 8 June 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Tayyib T.A. Hayat, Mary A. Rutherford We are entering a new era of understanding human development with the ability to perform studies at the earliest time points possible. There is a substantial body of evidence to support the concept that early motor behaviour originates from supraspinal motor centres, reflects neurological integrity, and that altered patterns of behaviour may precede clinical manifestation of disease. Cine Magnetic Resonance Imaging (cineMRI) has established its value as a novel method to visua...
Source: Neuroscience and Biobehavioral Reviews - June 8, 2018 Category: Neuroscience Source Type: research

The relationship between diffusion tensor imaging findings and cognitive outcomes following adult traumatic brain injury: A meta-analysis
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): E.J. Wallace, J.L. Mathias, L. Ward Cognitive impairments are common following a traumatic brain injury (TBI) and frequently result from white matter (WM) damage. This damage can be quantified using diffusion tensor imaging (DTI), which measures the directionality (fractional anisotropy: FA) and amount (mean diffusivity/apparent diffusion coefficient: MD/ADC) of water diffusion in WM, with high FA and low MD/ADC thought to indicate greater WM integrity. However, the relationship between DTI and cognitive outcomes is ...
Source: Neuroscience and Biobehavioral Reviews - June 8, 2018 Category: Neuroscience Source Type: research

Early Life Stress, Air Pollution, Inflammation, and Disease: An Integrative Review and Immunologic Model of Social-Environmental Adversity and Lifespan Health
Publication date: Available online 3 June 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Hector A. Olvera Alvarez, Laura D. Kubzansky, Matthew J. Campen, George M. Slavich Socially disadvantaged individuals are at greater risk for simultaneously being exposed to adverse social and environmental conditions. Although the mechanisms underlying joint effects remain unclear, one hypothesis is that toxic social and environmental exposures have synergistic effects on inflammatory processes that underlie the development of chronic diseases, including cardiovascular disease, diabetes, depression, and certain t...
Source: Neuroscience and Biobehavioral Reviews - June 4, 2018 Category: Neuroscience Source Type: research

A review of brain insulin signaling in mood disorders: From biomarker to clinical target
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Thanh Thanh L. Nguyen, Lily C. Chan, Kristin Borreginne, Rajas P. Kale, Chunling Hu, Susannah J. Tye Patients with mood disorders are at increased risk for metabolic dysfunction. Co-occurrence of the two conditions is typically associated with a more severe disease course and poorer treatment outcomes. The specific pathophysiological mechanisms underlying this bidirectional relationship between mood and metabolic dysfunction remains poorly understood. However, it is likely that impairment of metabolic processes withi...
Source: Neuroscience and Biobehavioral Reviews - May 26, 2018 Category: Neuroscience Source Type: research

The Neural Circuitry of Restricted Repetitive Behavior: Magnetic Resonance Imaging in Neurodevelopmental Disorders and Animal Models
Publication date: Available online 23 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): B.J. Wilkes, M.H. Lewis Restricted, repetitive behaviors (RRBs) are patterns of behavior that exhibit little variation in form and have no obvious function. RRBs although transdiagonstic are a particularly prominent feature of certain neurodevelopmental disorders, yet relatively little is known about the neural circuitry of RRBs. Past work in this area has focused on isolated brain regions and neurotransmitter systems, but implementing a neural circuit approach has the potential to greatly improve understanding of...
Source: Neuroscience and Biobehavioral Reviews - May 24, 2018 Category: Neuroscience Source Type: research

Mechanisms of cortisol – substance use development associations: Hypothesis generation through gene enrichment analysis
Publication date: Available online 23 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Kristine Marceau, Emily Abel There are many theories about the mechanisms of associations between hypothalamic-pituitary-adrenal (HPA) function (indexed by cortisol) and substance use. However, the potential for genes that contribute to both HPA function and substance use to confound the association (e.g., genetic confounding) has largely been ignored. We explore the potential role of genetics in cortisol-substance use associations, build a conceptual framework placing theories and mechanisms for how cortisol and ...
Source: Neuroscience and Biobehavioral Reviews - May 24, 2018 Category: Neuroscience Source Type: research

relationship between diffusion tensor imaging findings and cognitive outcomes following adult traumatic brain injury: A meta-analysis
Publication date: Available online 24 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): E.J. Wallace, J.L. Mathias, L. Ward Cognitive impairments are common following a traumatic brain injury (TBI) and frequently result from white matter (WM) damage. This damage can be quantified using diffusion tensor imaging (DTI), which measures the directionality (fractional anisotropy: FA) and amount (mean diffusivity/apparent diffusion coefficient: MD/ADC) of water diffusion in WM, with high FA and low MD/ADC thought to indicate greater WM integrity. However, the relationship between DTI and cognitive outcomes ...
Source: Neuroscience and Biobehavioral Reviews - May 24, 2018 Category: Neuroscience Source Type: research

Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition
Publication date: July 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 90 Author(s): F Sarubbo, D Moranta, G Pani The increased number of elderly people worldwide poses a major medical and socio-economic challenge: the search of strategies to combat the consequences of the aging process. Oxidative stress and inflammation have been pointed out as the leading causes of brain aging, which in turn alters the functionality of brain. In this context, decline in adult neurogenesis (AN), due to modifications in the neural progenitor stem cells (NSCs) and their microenvironment, is among the aging alterations cont...
Source: Neuroscience and Biobehavioral Reviews - May 23, 2018 Category: Neuroscience Source Type: research

Longitudinal assessment of chemotherapy-induced changes in brain and cognitive functioning: A systematic review
Publication date: Available online 20 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Mingmei Li, Karen Caeyenberghs In addition to the burden of a life-threatening diagnosis, cancer patients are struggling with adverse side-effects from cancer treatment. Chemotherapy has been linked to an array of cognitive impairments and alterations in brain structure and function (“chemobrain”). In this review, we summarized the existing evidence that evaluate the changes in cognitive functioning and brain with chemotherapy, as assessed using structural and functional MRI-based techniques in a longi...
Source: Neuroscience and Biobehavioral Reviews - May 21, 2018 Category: Neuroscience Source Type: research

TPH2 polymorphisms across the spectrum of psychiatric morbidity: A systematic review and meta-analysis
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Koen Willem Ottenhof, Mari Sild, Mélissa Luce Lévesque, Henricus Gerardus Ruhé, Linda Booij Tryptophan hydroxylase 2 (TPH2) is the rate-limiting enzyme in brain serotonin synthesis. The TPH2 gene has frequently been investigated in relation to psychiatric morbidity. The aim of the present review is to integrate results from association studies between TPH2 single nucleotide polymorphisms (SNPs) and various psychiatric disorders, which we furthermore quantified with meta-analysis. We reviewed 166 ...
Source: Neuroscience and Biobehavioral Reviews - May 20, 2018 Category: Neuroscience Source Type: research

Attention deficit/hyperactivity-disorder and obesity: A review and model of current hypotheses explaining their comorbidity
Publication date: September 2018 Source:Neuroscience & Biobehavioral Reviews, Volume 92 Author(s): Tomasz Hanć, Samuele Cortese Available meta-analyses point to a significant association between attention-deficit/hyperactivity disorder (ADHD) and obesity. The possible mechanisms underlying this relationship are unclear. Here, we overview the studies aimed at identifying the factors contributing to the comorbidity between ADHD and obesity, including genetic factors, fetal programming, executive dysfunctions, psychosocial stress, factors directly related to energy balance, and sleep patterns alterations. The bulk o...
Source: Neuroscience and Biobehavioral Reviews - May 20, 2018 Category: Neuroscience Source Type: research

A new outlook on cholinergic interneurons in Parkinson ’s disease and L-DOPA-induced dyskinesia
Publication date: Available online 18 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Melissa M. Conti, Nicole Chambers, Christopher Bishop Traditionally, dopamine (DA) and acetylcholine (ACh) striatal systems were considered antagonistic and imbalances or aberrant signaling between these neurotransmitter systems could be detrimental to basal ganglia activity and pursuant motor function, such as in Parkinson’s disease (PD) and L-DOPA-induced dyskinesia (LID). Herein, we discuss the involvement of cholinergic interneurons (ChIs) in striatally-mediated movement in a healthy, parkinsonian, and d...
Source: Neuroscience and Biobehavioral Reviews - May 19, 2018 Category: Neuroscience Source Type: research

Antenatal ultrasound value in risk calculation for Autism Spectrum Disorder: A systematic review to support future research
Publication date: Available online 17 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Francesca Fulceri, Andrea Guzzetta, Argyro Athanasiadou, Laura Iaconianni, Maria Luisa Scattoni There is a growing research interest on the antenatal features of children with neurodevelopmental disorders. Indeed, it has been proved that the neurodevelopment is, at least partly, affected by processes occurring in fetal life and that the early neurodevelopmental disorders identification is essential to optimize long-term outcomes. This systematic review aims to summarize findings on antenatal ultrasound data, which...
Source: Neuroscience and Biobehavioral Reviews - May 18, 2018 Category: Neuroscience Source Type: research

The cingulum bundle: Anatomy, function, and dysfunction
Publication date: Available online 10 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Emma J. Bubb, Claudia Metzler-Baddeley, John P. Aggleton The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its apparent continuity, the cingulum’s composition continually changes as fibres join and leave the bundle. To help understand its complex structure, this review begins with detailed, comparative descriptions of the multiple connections comprising the cingulum bundl...
Source: Neuroscience and Biobehavioral Reviews - May 17, 2018 Category: Neuroscience Source Type: research

Prostheses as extensions of the body: progress and challenges
Publication date: Available online 14 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Maria Niedernhuber, Damiano G. Barone, Bigna Lenggenhager Recent years have seen a surge of interest in the incorporation of artificial limbs. This research promises to provide individuals with sensorimotor disorders such as amputations with prostheses which feel like their own body part. While neuroscience made a leap towards uncovering the basic neurocognitive mechanisms of bodily self-consciousness, the development of incorporated prosthetic limbs still faces substantial challenges in basic neuroscience and in ...
Source: Neuroscience and Biobehavioral Reviews - May 15, 2018 Category: Neuroscience Source Type: research

Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: A systematic review and meta-analysis of randomised sham-controlled trials
We examined the efficacy and acceptability of non-invasive brain stimulation in adult unipolar and bipolar depression. Randomised sham-controlled trials of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and theta-burst stimulation (TBS), without co-initiation of another treatment, were included. We analysed effects on response, remission, all-cause discontinuation rates and continuous depression severity measures. Fifty-six studies met our criteria for inclusion (N  = 3,058, mean age = 44.96 years, 61.73% female). Response rates demonstrated efficacy of high-frequency rTMS o...
Source: Neuroscience and Biobehavioral Reviews - May 13, 2018 Category: Neuroscience Source Type: research

Early human motor development: From variation to the ability to vary and adapt
Publication date: Available online 9 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Mijna Hadders-Algra This review summarizes early human motor development. From early fetal age motor behavior is based on spontaneous neural activity: activity of networks in the brainstem and spinal cord that is modulated by supraspinal activity. The supraspinal activity, first primarily brought about by the cortical subplate, later by the cortical plate, induces movement variation. Initially, movement variation especially serves exploration; its associated afferent information is primarily used to sculpt the deve...
Source: Neuroscience and Biobehavioral Reviews - May 11, 2018 Category: Neuroscience Source Type: research

An Update on Contextual Fear Memory Mechanisms: Transition between Amygdala and Hippocampus
Publication date: Available online 9 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Nicholas Chaaya, Andrew R. Battle, Luke R. Johnson Context is an ever-present combination of discrete environmental elements capable of influencing many psychological processes. When context is associated with an aversive stimulus, a permanent contextual fear memory is formed. Context is hypothesized to greatly influence the treatability of various fear-based pathologies, in particular, post-traumatic stress disorder (PTSD). In order to understand how contextual fear memories are encoded and impact underlying fear ...
Source: Neuroscience and Biobehavioral Reviews - May 9, 2018 Category: Neuroscience Source Type: research

Neurocognitive effects of methylphenidate in adults with attention-deficit/hyperactivity disorder: A meta-analysis
Publication date: Available online 8 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Michelle A. Pievsky, Robert E. McGrath PIEVSKY, M. A., and R. E. McGrath. Neurocognitive effects of methylphenidate in adults with attention-deficit/hyperactivity disorder: A meta-analysis…NEUROSCI BIOBEHAV REV 81(1) XXX-XXX, 2017.- This meta-analysis summarized 21 double-blind randomized controlled trials with a mean study duration of 18 days comparing the neurocognitive functioning of adults with attention-deficit/hyperactivity disorder (ADHD) on methylphenidate vs placebo. Effect sizes were weighted using...
Source: Neuroscience and Biobehavioral Reviews - May 8, 2018 Category: Neuroscience Source Type: research

ADRA2B Deletion Variant and Enhanced Cognitive Processing of Emotional Information: A Meta-Analytical Review
Publication date: Available online 8 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Weizhen Xie, Marcus Cappiello, Ming Meng, Robert Rosenthal, Weiwei Zhang This meta-analytical review examines whether a deletion variant in ADRA2B, a gene that encodes α2B adrenoceptor in the regulation of norepinephrine availability, influences cognitive processing of emotional information in human observers. Using a multilevel modeling approach, this meta-analysis of 16 published studies with a total of 2,752 participants showed that ADRA2B deletion variant was significantly associated with enhanced percept...
Source: Neuroscience and Biobehavioral Reviews - May 8, 2018 Category: Neuroscience Source Type: research

How do hypothalamic nonapeptides shape youth ’s sociality? A systematic review on oxytocin, vasopressin and human socio-emotional development
Publication date: Available online 5 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Nuno Torres, Daniel Martins, António J. Santos, Diana Prata, Maria Veríssimo The hypothalamic nonapeptides oxytocin and vasopressin are important modulators of socio-affective behaviours in a wide variety of animal species, including humans. Nevertheless, there is little research addressing their possible roles on socio-affective dimensions of human behaviour across development, during which considerable behavioural and physiological change occurs. Questions still remain about the extent to which find...
Source: Neuroscience and Biobehavioral Reviews - May 7, 2018 Category: Neuroscience Source Type: research

The spatial representation of number, time, and serial order following sensory deprivation: a systematic review
Publication date: Available online 7 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Luca Rinaldi, Lotfi B. Merabet, Tomaso Vecchi, Zaira Cattaneo The spatial representation of numerical and temporal information is thought to be rooted in our multisensory experiences. Accordingly, we may expect visual or auditory deprivation to affect the way we represent numerical magnitude and time spatially. Here, we systematically review recent findings on how blind and deaf individuals represent abstract concepts such as magnitude and time (e.g., past/future, serial order of events) in a spatial format. Intere...
Source: Neuroscience and Biobehavioral Reviews - May 7, 2018 Category: Neuroscience Source Type: research

Animal models of binge drinking, current challenges to improve face validity
Publication date: Available online 5 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Jérôme Jeanblanc, Benjamin Rolland, Fabien Gierski, Margaret P. Martinetti, Mickael Naassila Binge drinking (BD), i.e., consuming a large amount of alcohol in a short period of time, is an increasing public health issue. Though no clear definition has been adopted worldwide the speed of drinking seems to be a keystone of this behavior. Developing relevant animal models of BD is a priority for gaining a better characterization of the neurobiological and psychobiological mechanisms underlying this danger...
Source: Neuroscience and Biobehavioral Reviews - May 5, 2018 Category: Neuroscience Source Type: research

Basal Ganglia and Beyond: the interplay between motor and cognitive aspects in Parkinson ’s disease Rehabilitation
Publication date: Available online 4 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Davide Ferrazzoli, Paola Ortelli, Graziella Madeo, Nir Giladi, Giselle M. Petzinger, Giuseppe Frazzitta Parkinson’s disease (PD) is characterized by motor and cognitive dysfunctions, affecting the motor behaviour. We summarize evidence that the interplay between motor and cognitive approaches is crucial in PD rehabilitation. Rehabilitation is complementary to pharmacological therapy and effective in reducing the PD disturbances, probably acting by inducing neuroplastic effects. The motor behaviour results fro...
Source: Neuroscience and Biobehavioral Reviews - May 4, 2018 Category: Neuroscience Source Type: research

Cognitive benefits of Angiotensin IV and Angiotensin-(1-7): a systematic review of experimental studies
Conclusion Studies of cognitive impairment show salutary effects of acute administration of Ang IV and its analogs, as well as AT4R activation. Brain RAS peptides appear most effective administered intracerebroventricularly, close to the time of learning acquisition or retention testing. Ang-(1-7) shows anti-dementia qualities. (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - May 4, 2018 Category: Neuroscience Source Type: research

Individual differences in risk taking and endogeneous levels of testosterone, estradiol, and cortisol: A systematic literature search and three independent meta-analyses
Publication date: Available online 3 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Jennifer Kurath, Rui Mata Hormonal levels have been hypothesized to serve as proximal biological mechanisms underlying individual differences in risk taking. We conducted a systematic literature search and independent meta-analyses to assess the link between endogenous testosterone, estradiol, and cortisol levels and risk-taking related constructs (i.e., risk-taking propensity, impulsivity, sensation seeking, novelty seeking). We found small correlations between risk-taking constructs and testosterone (r = 0.12...
Source: Neuroscience and Biobehavioral Reviews - May 3, 2018 Category: Neuroscience Source Type: research

Current Perspectives on the Cerebellum and Reading Development
Publication date: Available online 3 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Travis A. Alvarez, Julie A. Fiez The dominant neural models of typical and atypical reading focus on the cerebral cortex. However, Nicolson et al. (2001) proposed a model, the cerebellar deficit hypothesis, in which the cerebellum plays an important role in reading. To evaluate the evidence in support of this model, we qualitatively review the current literature and employ meta-analytic tools examining patterns of functional connectivity between the cerebellum and the cerebral reading network. We find evidence for ...
Source: Neuroscience and Biobehavioral Reviews - May 3, 2018 Category: Neuroscience Source Type: research

Towards a human self-regulation system: Common and distinct neural signatures of emotional and behavioural control
Publication date: Available online 3 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Robert Langner, Susanne Leiberg, Felix Hoffstaedter, Simon B. Eickhoff Self-regulation refers to controlling our emotions and actions in the pursuit of higher-order goals. Although research suggests commonalities in the cognitive control of emotion and action, evidence for a shared neural substrate is scant and largely circumstantial. Here we report on two large-scale meta-analyses of human neuroimaging studies on emotion or action control, yielding two fronto-parieto-insular networks. The networks’ overlap, ...
Source: Neuroscience and Biobehavioral Reviews - May 3, 2018 Category: Neuroscience Source Type: research

Chloride transporters and GABA polarity in developmental, neurological and psychiatric conditions
Publication date: Available online 2 May 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Joran T. Schulte, Corette J. Wierenga, Hilgo Bruining Neuronal chloride regulation is a determinant factor for the dynamic tuning of GABAergic inhibition during and beyond brain development. This regulation is mainly dependent on the two co-transporters K+/Cl- co-transporter KCC2 and Na+/K+/Cl- co-transporter NKCC1, whose activity can decrease or increase neuronal chloride concentrations respectively. Altered expression and/or activity of either of these co-transporters has been associated with a wide variety of br...
Source: Neuroscience and Biobehavioral Reviews - May 2, 2018 Category: Neuroscience Source Type: research

Maturation of vocal emotion recognition: Insights from the developmental and neuroimaging literature
Publication date: Available online 27 April 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): Michele Morningstar, Eric E. Nelson, Melanie A. Dirks Emotions are implicitly expressed in both facial expressions and prosodic components of vocal communication. The ability to recognize nonverbal cues of emotion is an important feature of social competence that matures gradually across childhood and adolescence. Compared to the extensive knowledge about the development of emotion recognition (ER) from facial displays of emotion, relatively little is known about the maturation of this ability in the auditory do...
Source: Neuroscience and Biobehavioral Reviews - April 28, 2018 Category: Neuroscience Source Type: research

The neuroanatomic complexity of the CRF and DA systems and their interface: What we still don ’t know
Publication date: Available online 25 April 2018 Source:Neuroscience & Biobehavioral Reviews Author(s): E.A. Kelly, J.L. Fudge Corticotropin-releasing factor (CRF) is a neuropeptide that mediates the stress response. Long known to contribute to regulation of the adrenal stress response initiated in the hypothalamic-pituitary axis (HPA), a complex pattern of extrahypothalamic CRF expression is also described in rodents and primates. Cross-talk between the CRF and midbrain dopamine (DA) systems links the stress response to DA regulation. Classically CRF+ cells in the extended amygdala and paraventricular nucleus (PV...
Source: Neuroscience and Biobehavioral Reviews - April 26, 2018 Category: Neuroscience Source Type: research