Social Touch During Development: Long-Term Effects on Brain and Behavior
Publication date: Available online 29 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): K.L. Bales, L.R. Witczak, T.C. Simmons, L.E. Savidge, E.S. Rothwell, F.D. Rogers, R.A. Manning, M.J. Heise, M. Englund, R. Arias del RazoAbstractIn this paper, our goal is to explore what is known about the role of social touch during development. We first address the neural substrates of social touch and the role of tactile experience in neural development. We discuss natural variation in early exposure to social touch, followed by a discussion on experimental manipulations of social touch during development and ...
Source: Neuroscience and Biobehavioral Reviews - October 4, 2018 Category: Neuroscience Source Type: research

Healthy play, better coping: The importance of play for the development of children in health and disease
Publication date: Available online 29 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Sanne L. Nijhof, Christiaan H. Vinkers, Stefan M. van Geelen, Sasja N. Duijff, E.J. Marijke Achterberg, Janjaap van der Net, Remco C. Veltkamp, Martha A. Grootenhuis, Elise M. van de Putte, Manon H.J. Hillegers, Anneke W. van der Brug, Corette J. Wierenga, Manon J.N.L. Benders, Rutger C.M.E. Engels, C. Kors van der Ent, Louk J.M.J. Vanderschuren, Heidi M.B. LesscherAbstractPlay is of vital importance for the healthy development of children. From a developmental perspective, play offers ample physical, emotional, c...
Source: Neuroscience and Biobehavioral Reviews - October 4, 2018 Category: Neuroscience Source Type: research

Meta-analyses of the neural mechanisms and predictors of response to psychotherapy in depression and anxiety
Publication date: Available online 29 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Lindsey Marwood, Toby Wise, Adam M. Perkins, Anthony J. CleareAbstractUnderstanding the neural mechanisms underlying psychological therapy could aid understanding of recovery processes and help target treatments. The dual-process model hypothesises that psychological therapy is associated with increased emotional-regulation in prefrontal brain regions and decreased implicit emotional-reactivity in limbic regions; however, research has yielded inconsistent findings. Meta-analyses of brain activity changes accompany...
Source: Neuroscience and Biobehavioral Reviews - October 4, 2018 Category: Neuroscience Source Type: research

Audiovisual Multisensory Integration in Individuals with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
Publication date: Available online 1 October 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Jacob I. Feldman, Kacie Dunham, Margaret Cassidy, Mark T. Wallace, Yupeng Liu, Tiffany G. WoynaroskiAbstractAn ever-growing literature has aimed to determine how individuals with autism spectrum disorder (ASD) differ from their typically developing (TD) peers on measures of multisensory integration (MSI) and to ascertain the degree to which differences in MSI are associated with the broad range of symptoms associated with ASD. Findings, however, have been highly variable across the studies carried out to date. The pr...
Source: Neuroscience and Biobehavioral Reviews - October 4, 2018 Category: Neuroscience Source Type: research

The Effects of Exercise on Cognition and Gait in Parkinson’s disease: A Scoping Review
Publication date: Available online 3 October 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Brittany Intzandt, Eric N. Beck, Carolina R.A. SilveiraAbstractCognitive and gait deficits are two debilitating symptoms that occur in Parkinson’s disease (PD). Importantly, a relationship between cognitive and gait deficits exists in PD, suggesting reliance on cognition is increased to compensate for gait deficits and/or deterioration of cognition and gait may share common mechanisms. Rehabilitation strategies targeting one factor could lead to the improvement of the other, presenting a unique opportunity to t...
Source: Neuroscience and Biobehavioral Reviews - October 4, 2018 Category: Neuroscience Source Type: research

Neuromodulation for substance addiction in human subjects: A review
Publication date: December 2018Source: Neuroscience & Biobehavioral Reviews, Volume 95Author(s): Ausaf Bari, Jasmine DeCisare, Diana Babayan, Mariama Runcie, Hiro Sparks, Bayard WilsonAbstractSubstance abuse is one of the most prevalent and costly health problems in the world today. Standard medical therapy is often not curative, and relapse is common. Research over the past several decades on the neural underpinnings of addiction has implicated a network of structures within the brain shown to be altered in patients with substance abuse. The field of neuromodulation aims to utilize this knowledge to treat dysfunctiona...
Source: Neuroscience and Biobehavioral Reviews - October 4, 2018 Category: Neuroscience Source Type: research

Social brain, social dysfunction and social withdrawal
Publication date: Available online 20 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Stefano Porcelli, Nic Van Der Wee, Steven van der Werff, Moji Aghajani, Jeffrey C. Glennon, Sabrina van Heukelum, Floriana Mogavero, Antonio Lobo, Francisco Javier Olivera, Elena Lobo, Mar Posadas, Juergen Dukart, Rouba Kozak, Estibaliz Arce, Arfan Ikram, Jacob Vorstman, Amy Bilderbeck, Ilja Saris, Martien J. Kas, Alessandro SerrettiAbstractThe human social brain is complex. Current knowledge fails to define the neurobiological processes underlying social behaviour involving the (patho-) physiological mechanisms t...
Source: Neuroscience and Biobehavioral Reviews - September 21, 2018 Category: Neuroscience Source Type: research

Intranasal Oxytocin and OXTR Genotype Effects on Resting State Functional Connectivity: A Systematic Review
DiscussionIN-OT appears to modulate resting state functional connectivity in a manner similar to its effects on task fMRI, consistent with hypothesized models of IN-OT. However, conclusions are limited by the narrow range of neuroanatomical seed regions, and methodological and experimental design heterogeneity. Future studies should take into account individual differences. Findings may provide insight into mechanisms through which IN-OT impacts human behavior. (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - September 21, 2018 Category: Neuroscience Source Type: research

Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies
Publication date: Available online 19 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Anita C. Hansson, Gerhard Gründer, Natalie Hirth, Hamid R. Noori, Rainer Spanagel, Wolfgang H. SommerAbstractA major hypothesis in the addiction field suggests deficits in dopamine signaling during abstinence as a driving mechanism for the relapsing course of the disorder. Paradoxically, blockade of mu-opioid receptors (MORs) intended to suppress dopamine release and alcohol reward is a widely used treatment for preventing relapse in alcohol use disorder (AUD). To elucidate this apparent discrepancy, we syste...
Source: Neuroscience and Biobehavioral Reviews - September 21, 2018 Category: Neuroscience Source Type: research

Motor dysfunction as research domain across bipolar, obsessive-compulsive and neurodevelopmental disorders
Publication date: Available online 17 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Dusan Hirjak, Andreas Meyer-Lindenberg, Stefan Fritze, Fabio Sambataro, Katharina M. Kubera, Robert C. WolfAbstractAlthough genuine motor abnormalities (GMA) are frequently found in schizophrenia, they are also considered as an intrinsic feature of bipolar, obsessive-compulsive, and neurodevelopmental disorders with early onset such as autism, ADHD, and Tourette syndrome. Such transnosological observations strongly suggest a common neural pathophysiology. This systematic review highlights the evidence on GMA and t...
Source: Neuroscience and Biobehavioral Reviews - September 18, 2018 Category: Neuroscience Source Type: research

Neural coding: A single neuron’s perspective
Publication date: Available online 15 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Alireza Azarfar, Niccoló Calcini, Chao Huang, Fleur Zeldenrust, Tansu CelikelAbstractWhat any sensory neuron knows about the world is one of the cardinal questions in Neuroscience. Information from the sensory periphery travels across synaptically coupled neurons as each neuron encodes information by varying the rate and timing of its action potentials (spikes). Spatiotemporally correlated changes in this spiking regimen across neuronal populations are the neural basis of sensory representations. In the som...
Source: Neuroscience and Biobehavioral Reviews - September 17, 2018 Category: Neuroscience Source Type: research

Addiction and Stress: An Allostatic View
Publication date: Available online 15 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): George F. Koob, Jay SchulkinAbstractAllostasis, or stability through change, has most often been linked with challenges to homeostasis, in which repeated challenges or stressors produce sufficient allostatic load to generate an allostatic state that can ultimately lead to a disease state. The present review argues that the impact of stress on drug addiction fits with an allostatic model and represents a challenge to brain circuit regulatory mechanisms that underlie the emotional state of the animal. The central th...
Source: Neuroscience and Biobehavioral Reviews - September 17, 2018 Category: Neuroscience Source Type: research

New synthetic opioids: Part of a new addiction landscape
Publication date: Available online 12 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Laurent Karila, Maude Marillier, Boris Chaumette, Joel Billieux, Franchitto Nicolas, Benyamina AmineAbstractSynthetic opioids (SO) are a major risk for public health across the world. These drugs can be divided into 2 categories, pharmaceutical and non-pharmaceutical fentanyls. A new generation of SO has emerged on the drug market since 2010. North America is currently facing an opioid epidemic of morbi-mortality, caused by over-prescription of opioids, illegally diverted prescribed medicines, the increasing use o...
Source: Neuroscience and Biobehavioral Reviews - September 12, 2018 Category: Neuroscience Source Type: research

Biomarker correlates of psychotherapy outcomes in borderline personality disorder: A systematic review
Publication date: Available online 9 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Ely M. Marceau, Denise Meuldijk, Michelle L. Townsend, Nadia Solowij, Brin F.S. GrenyerAbstractStudies of neurobiological mechanisms in borderline personality disorder (BPD) have increased our understanding of the pathophysiology of its development and course. Less is known about how psychotherapy may influence these neurobiological factors, and also whether biomarkers may predict psychotherapy outcomes. We conducted a systematic review using PRISMA guidelines. Fourteen studies providing data from 467 participants ...
Source: Neuroscience and Biobehavioral Reviews - September 10, 2018 Category: Neuroscience Source Type: research

Neuroepigenetics and addictive behaviors: where do we stand?
Publication date: Available online 8 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): David de Sa Nogueira, Karine Merienne, Katia BefortAbstractSubstance use disorders involve long-term changes in the brain that lead to compulsive drug seeking, craving, and a high probability of relapse. Recent findings have highlighted the role of epigenetic regulations in controlling chromatin access and regulation of gene expression following exposure to drugs of abuse. In the present review, we focus on data investigating genome-wide epigenetic modifications in the brain of addicted patients or in rodent models...
Source: Neuroscience and Biobehavioral Reviews - September 9, 2018 Category: Neuroscience Source Type: research

Adolescence as a neurobiological critical period for the development of higher-order cognition
Publication date: Available online 7 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Bart Larsen, Beatriz LunaAbstractThe transition from adolescence to adulthood is characterized by improvements in higher-order cognitive abilities and corresponding refinements of the structure and function of the brain regions that support them. Whereas the neurobiological mechanisms that govern early development of sensory systems are well-understood, the mechanisms that drive developmental plasticity of association cortices, such as prefrontal cortex (PFC), during adolescence remain to be explained. In this revi...
Source: Neuroscience and Biobehavioral Reviews - September 8, 2018 Category: Neuroscience Source Type: research

Effects of early life stress on biochemical indicators of the dopaminergic system: a 3 level meta-analysis of rodent studies
Publication date: Available online 7 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): V. Bonapersona, M. Joëls, R.A. SarabdjitsinghAbstractAdverse early life events are a well-established risk factor for the precipitation of behavioral disorders characterized by anomalies in the dopaminergic system, such as schizophrenia and addiction. The correlation between early life conditions and the dopaminergic system has been causally investigated in more than 90 rodent publications. Here, we tested the validity of the hypothesis that early life stress (ELS) alters dopamine signaling by performing an ex...
Source: Neuroscience and Biobehavioral Reviews - September 8, 2018 Category: Neuroscience Source Type: research

The role of inflammation in core features of depression: Insights from paradigms using exogenously-induced inflammation
Publication date: Available online 7 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Larissa N. Dooley, Kate R. Kuhlman, Theodore F. Robles, Naomi I. Eisenberger, Michelle G. Craske, Julienne E. BowerAbstractA wealth of evidence has implicated inflammation in the development of depression. Yet, the heterogeneous nature of depression has impeded efforts to understand, prevent, and treat the disease. The purpose of this integrative review is to summarize the connections between inflammation and established core features of depression that exhibit more homogeneity than the syndrome itself: exaggerated...
Source: Neuroscience and Biobehavioral Reviews - September 8, 2018 Category: Neuroscience Source Type: research

Electrophysiological Assessment Methodology of Sensory Processing Dysfunction in Schizophrenia and Dementia of the Alzheimer Type
This article describes aspects of a research project whose aim is to delineate the neurobiology that may underlie Social Withdrawal in Alzheimer’s disease, Schizophrenia and Major Depression. This is a European-funded IMI 2 project, identified as PRISM (Psychiatric Ratings using Intermediate Stratified Markers). This paper focuses specifically on the selected electrophysiological paradigms chosen based on a comprehensive review of all relevant literature and practical constraints. The choice of the electrophysiological biomarkers were fundamentality based their metrics and capacity to discriminate between populations...
Source: Neuroscience and Biobehavioral Reviews - September 7, 2018 Category: Neuroscience Source Type: research

Targeting the gut microbiota to influence brain development and function in early life
Publication date: Available online 6 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Shugui Wang, Louise Harvey, Rocio Martin, Eline M. van der Beek, Jan Knol, John Cryan, Ingrid B. RenesAbstractIn the first 2 – 3 years of life, the gut microbiota of infants quickly becomes diverse and rich. Disruptions in the evolving gut microbiota during this critical developmental period can impact brain development. Communication between the microbiota, gut and brain is driven by hormonal and neural regulation, as well as immune and metabolic pathways, however, our understanding of how the parallel devel...
Source: Neuroscience and Biobehavioral Reviews - September 7, 2018 Category: Neuroscience Source Type: research

Growing out of attention deficit hyperactivity disorder: insights from the ‘remitted’ brain
Publication date: Available online 5 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Gustavo Sudre, Aman Mangalmurti, Philip ShawAbstractWe consider developmental and cognitive models to explain why some children ‘grow out’ of attention deficit hyperactivity disorder (ADHD) by adulthood. The first model views remission as a convergence towards more typical brain function and structure. In support, some studies find that adult remitters are indistinguishable from those who were never affected in the neural substrates of 'top-down' mechanisms of cognitive control, some 'bottom-up' process...
Source: Neuroscience and Biobehavioral Reviews - September 6, 2018 Category: Neuroscience Source Type: research

Cognitive-motor interference during gait in patients with multiple sclerosis: a mixed methods systematic review
ConclusionsCMI should be assessed in MS with a standardised dual task such as the Verbal Fluency task while walking, with measurements of the double support time and the effect on the cognitive task. The clinical usefulness of CMI in the assessment of patients with MS is discussed. (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - September 4, 2018 Category: Neuroscience Source Type: research

Non-pharmacological factors that determine drug use and addiction
Publication date: Available online 1 September 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Serge H. Ahmed, Aldo Badiani, Klaus A. Miczek, Christian P. MüllerAbstractBased on their pharmacological properties, psychoactive drugs are supposed to take control of the natural reward system to finally drive compulsory drug seeking and consumption. However, psychoactive drugs are not used in an arbitrary way as pure pharmacological reinforcement would suggest, but rather in a highly specific manner depending on non-pharmacological factors. While pharmacological effects of psychoactive drugs are well studied...
Source: Neuroscience and Biobehavioral Reviews - September 3, 2018 Category: Neuroscience Source Type: research

Glucocorticoid receptor gene (NR3C1) DNA methylation in association with trauma, psychopathology, transcript expression, or genotypic variation: A systematic review
Publication date: Available online 31 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Oliver J. Watkeys, Kyle Kremerskothen, Yann Quidé, Janice M. Fullerton, Melissa J. GreenAbstractThe glucocorticoid receptor gene (NR3C1) is a critical component of the stress response system. Cytosine methylation of NR3C1 has been repeatedly associated with trauma and mental disorders, including major depression, post-traumatic stress disorder, anxiety, and personality disorders, suggesting that NR3C1 methylation may play a role in stress-related psychopathology. We systematically reviewed 55 studies examining...
Source: Neuroscience and Biobehavioral Reviews - September 1, 2018 Category: Neuroscience Source Type: research

The impact of early life stress on the central oxytocin system and susceptibility for drug addiction: applicability of oxytocin as a pharmacotherapy
Publication date: Available online 30 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Sarah J. Baracz, Nicholas A. Everett, Jennifer L. CornishAbstractEarly life trauma is strongly associated with an increased vulnerability to abuse illicit drugs and the impairment of neural development. This includes alterations to the development of the oxytocin system, which plays a pivotal role in the regulation of social behaviours and emotion. Dysregulation of this important system also contributes to increased susceptibility to develop drug addiction. In this review, we provide an overview of the animal models ...
Source: Neuroscience and Biobehavioral Reviews - August 31, 2018 Category: Neuroscience Source Type: research

Intelligence and Uncertainty: Implications of Hierarchical Predictive Processing for the Neuroscience of Cognitive Ability
Publication date: Available online 25 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Matthew J. EulerAbstractHierarchical predictive processing (PP) has recently emerged as a candidate theoretical paradigm for neurobehavioral research. To date, PP has found support through its success in offering compelling explanations for a number of perceptual, cognitive, and psychiatric phenomena, as well as from accumulating neurophysiological evidence. However, its implications for understanding intelligence and its neural basis have received relatively little attention. The present review outlines the key tene...
Source: Neuroscience and Biobehavioral Reviews - August 26, 2018 Category: Neuroscience Source Type: research

Amygdala and oxytocin functioning as keys to understanding and treating autism: Commentary on an RDoC based approach
Publication date: Available online 24 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Katrin Preckel, Philipp KanskeAbstractThe recent review by Hennessey, Andari and Rainnie (2018) utilizes the proposed Research Domain Criteria (RDoC) to classify amygdala functions and relate them to autism symptomatology. This approach has the potential to challenge the overarching autism diagnosis by furthering our knowledge of the mechanisms giving rise to autism psychopathology and generate novel treatment options. The purpose of this commentary is to provide additional information on a number of points raised in...
Source: Neuroscience and Biobehavioral Reviews - August 25, 2018 Category: Neuroscience Source Type: research

Low on Energy? An energy supply-demand perspective on stress and depression
Publication date: Available online 23 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Leif Østergaard, Martin Balslev Jørgensen, Gitte Moos KnudsenAbstractAre energy demands too high, or our energy resources either too low or inappropriately prioritized, as we develop stress and/or depression? We review evidence of dysregulated cellular energy homeostasis and energy depletion in stress and depression, identifying factors that might limit energy substrate availability. Resetting of cellular energy-sensors, splanchnic hypoxia, and catecholamine effects on blood viscosity emerge as mechanis...
Source: Neuroscience and Biobehavioral Reviews - August 24, 2018 Category: Neuroscience Source Type: research

A Systematic Review of Task-Based Functional Neuroimaging Studies Investigating Language, Semantic and Executive Processes in Thought Disorder
Publication date: Available online 22 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Philip J. Sumner, Imogen H. Bell, Susan L. RossellAbstractThe aim of the current systematic review was to synthesise the research that has investigated thought disorder (TD) using task-based functional neuroimaging techniques to target executive, language, or semantic functions. Thirty-seven pertinent studies were identified from January 1990 to August 2016. Functional correlates of TD included the superior and middle temporal, fusiform, and inferior frontal gyri bilaterally, as well as the left and right cingulate c...
Source: Neuroscience and Biobehavioral Reviews - August 24, 2018 Category: Neuroscience Source Type: research

Meta-Analysis of Cognitive Ability Differences by Apolipoprotein E Genotype in Young Humans
Publication date: Available online 17 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Gali H. Weissberger, Daniel A. Nation, Caroline P. Nguyen, Mark W. Bondi, S. Duke HanAbstractThe apolipoprotein (APOE) ε4 allele has been proposed as an example of an antagonistic pleiotropy gene, conferring a beneficial effect on cognition in early life and a detrimental impact on cognition during later years. However, findings on the cognitive associations of the ε4 allele in younger persons are mixed. This PRISMA conforming study aimed to investigate APOE genotype (e4/non-e4) associations across se...
Source: Neuroscience and Biobehavioral Reviews - August 18, 2018 Category: Neuroscience Source Type: research

Balancing between the two: are freezing of gait and postural instability in Parkinson’s disease connected?
Publication date: Available online 17 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): E.M.J. Bekkers, B.W. Dijkstra, E. Heremans, S.M.P. Verschueren, B.R. Bloem, A. NieuwboerABSTRACTPostural instability and freezing of gait (FoG) are key features of Parkinson’s disease (PD) closely related to falls. Growing evidence suggests that co-existing postural deficits could influence the occurrence and severity of FoG. To date, the exact nature of this interrelationship remains largely unknown. We analyzed the complex interaction between postural instability and gait disturbance by comparing the findings...
Source: Neuroscience and Biobehavioral Reviews - August 17, 2018 Category: Neuroscience Source Type: research

“Pure apathy” and cognitive dysfunctions in Parkinson’s disease: A meta-analytic study
Publication date: Available online 13 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Alfonsina D’Iorio, Gianpaolo Maggi, Carmine Vitale, Luigi Trojano, Gabriella SantangeloAbstractParkinson’s Disease (PD) is characterized by motor and non-motor symptoms such as cognitive deficit and behavioural disturbances. Apathy seems to be related to cognitive impairment, but some studies failed to confirm the relationship due to different methodological procedures across studies. A meta-analysis on 8 studies was performed to explore the cognitive correlates of apathy without depression and dementia (...
Source: Neuroscience and Biobehavioral Reviews - August 14, 2018 Category: Neuroscience Source Type: research

The PRISM Project: Social Withdrawal from an RDoC Perspective
Publication date: Available online 11 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Bruce N. CuthbertAbstractThe PRISM (Psychiatric Ratings using Intermediate Stratified Markers) project was funded under the auspices of the European Union Innovative Medicine Initiative (EU-IMI) to explore quantitative approaches to the biological and behavioral aspects of neuropsychiatric disorders. PRISM focuses specifically on social withdrawal, although its principles are applicable to a wide range of disorders. This commentary explores some of the major aspects of the PRISM design from the perspective of the Res...
Source: Neuroscience and Biobehavioral Reviews - August 11, 2018 Category: Neuroscience Source Type: research

Editorial Board
Publication date: October 2018Source: Neuroscience & Biobehavioral Reviews, Volume 93Author(s): (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - August 10, 2018 Category: Neuroscience Source Type: research

Advanced Biomarkers of Pediatric Mild Traumatic Brain Injury: Progress and Perils
Publication date: Available online 9 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Andrew R. Mayer, Mayank Kaushal, Andrew B. Dodd, Faith M. Hanlon, Nicholas A. Shaff, Rebekah Mannix, Christina L. Master, John J. Leddy, David Stephenson, Christopher J. Wertz, Elizabeth M. Suelzer, Kristy B. Arbogast, Timothy B. MeierAbstractThere is growing public concern about neurodegenerative changes (e.g., Chronic Traumatic Encephalopathy) that may occur chronically following clinically apparent and clinically silent (i.e., subconcussive blows) pediatric mild traumatic brain injury (pmTBI). However, there are cu...
Source: Neuroscience and Biobehavioral Reviews - August 10, 2018 Category: Neuroscience Source Type: research

Neural Correlates of Action: Comparing Meta-Analyses of Imagery, Observation, and Execution
Publication date: Available online 9 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Robert M. Hardwick, Svenja Caspers, Simon B Eickhoff, Stephan P SwinnenAbstractSeveral models propose Motor Imagery, Action Observation, and Movement Execution recruit the same brain regions. There is, however, no quantitative synthesis of the literature that directly compares their respective networks. Here we summarized data from neuroimaging experiments examining Motor Imagery (303 experiments, 4,902 participants), Action Observation (595 experiments, 11,032 participants), and related control tasks involving Moveme...
Source: Neuroscience and Biobehavioral Reviews - August 10, 2018 Category: Neuroscience Source Type: research

Adhering to best practice guidelines in outcomes measurement
Publication date: Available online 4 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): David Morley, Crispin Jenkinson (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - August 5, 2018 Category: Neuroscience Source Type: research

Cerebral correlates of Imitation of Intransitive Gestures: An Integrative Review of Neuroimaging Data and Brain Lesion Studies
Publication date: Available online 4 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Mathieu Lesourd, François Osiurak, Josselin Baumard, Angela Bartolo, Tim Vanbellingen, Emanuelle ReynaudAbstractThe aim of the present review is to investigate the cerebral correlates, more particularly the role of the parietal lobe, when imitating intransitive gestures, a task highly sensitive to apraxic errors. By providing an integrative review of functional imaging and brain lesion studies, we focused our attention on the meaning of gestures (meaningful and meaningless) and the body parts (finger and hand)....
Source: Neuroscience and Biobehavioral Reviews - August 5, 2018 Category: Neuroscience Source Type: research

Editorial Board
Publication date: September 2018Source: Neuroscience & Biobehavioral Reviews, Volume 92Author(s): (Source: Neuroscience and Biobehavioral Reviews)
Source: Neuroscience and Biobehavioral Reviews - August 3, 2018 Category: Neuroscience Source Type: research

Systematic review of Drosophila short-term-memory genetics: Meta-analysis reveals robust reproducibility
Publication date: Available online 2 August 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Tayfun Tumkaya, Stanislav Ott, Adam Claridge-ChangAbstractGeneticists use olfactory conditioning in Drosophila to identify learning genes; however, little is known about how these genes are integrated into short-term memory (STM) pathways. Here, we investigated the hypothesis that the STM evidence base is weak. We performed systematic review and meta-analysis of the field. Using metrics to quantify variation between discovery articles and follow-up studies, we found that seven genes were both highly replicated, and hi...
Source: Neuroscience and Biobehavioral Reviews - August 3, 2018 Category: Neuroscience Source Type: research

Ketogenic diet as a metabolic therapy for mood disorders: evidence and developments
Publication date: Available online 31 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Elisa Brietzke, Rodrigo B. Mansur, Mehala Subramaniapillai, Vicent Balanzá Martinez, Maj Vinberg, Ana González-Pinto, Joshua D. Rosenblat, Roger Ho, Roger S. McIntyreABSTRACTDespite significant advances in pharmacological and non-pharmacological treatments, mood disorders remain a significant source of mental capital loss, with high rates of treatment resistance, requiring a coordinated effort in investigation and development of efficient, tolerable and accessible novel interventions. Ketogenic diet (KD) ...
Source: Neuroscience and Biobehavioral Reviews - August 1, 2018 Category: Neuroscience Source Type: research

Mind wandering perspective on attention-deficit/hyperactivity disorder
Publication date: September 2018Source: Neuroscience & Biobehavioral Reviews, Volume 92Author(s): Natali S. Bozhilova, Giorgia Michelini, Jonna Kuntsi, Philip AshersonAbstractAttention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder associated with a range of mental health, neurocognitive and functional problems. Although the diagnosis is based on descriptions of behaviour, individuals with ADHD characteristically describe excessive spontaneous mind wandering (MW). MW in individuals with ADHD reflects constant mental activity which lacks topic stability and content consistency. Based on th...
Source: Neuroscience and Biobehavioral Reviews - July 31, 2018 Category: Neuroscience Source Type: research

Hungry Brains: A Meta-Analytical Review of Brain Activation Imaging Studies On Food Perception and Appetite in Obese Individuals
Publication date: Available online 30 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): F. Devoto, L. Zapparoli, R. Bonandrini, M. Berlingeri, A. Ferrulli, L. Luzi, G. Banfi, E. PaulesuAbstractThe dysregulation of food intake in chronic obesity has been explained by different theories. To assess their explanatory power, we meta-analyzed 22 brain-activation imaging studies. We found that obese individuals exhibit hyper-responsivity of the brain regions involved in taste and reward for food-related stimuli. Consistent with a Reward Surfeit Hypothesis, obese individuals exhibit a ventral striatum hyper-respo...
Source: Neuroscience and Biobehavioral Reviews - July 31, 2018 Category: Neuroscience Source Type: research

The Role of Epigenetic Modifications in Neurodevelopmental Disorders: A Systematic Review
Publication date: Available online 29 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Lorenza Dall’Aglio, Taulant Muka, Charlotte A.M. Cecil, Wichor M. Bramer, Michael M.P.J. Verbiest, Jana Nano, Andrea Cortes Hidalgo, Oscar H. Franco, Henning TiemeierAbstractEpigenetic processes have been suggested as key mechanisms in the etiology of neurodevelopmental disorders. This systematic review summarizes the current evidence for an association between epigenetics and Autism Spectrum Disorder (ASD) and Attention/Deficit-Hyperactivity Disorder (ADHD). Six databases were searched until the 24th of October ...
Source: Neuroscience and Biobehavioral Reviews - July 30, 2018 Category: Neuroscience Source Type: research

Functional neuroanatomy of peripheral inflammatory physiology: A meta-analysis of human neuroimaging studies
Publication date: Available online 29 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Thomas E. Kraynak, Anna L. Marsland, Tor D. Wager, Peter J. GianarosAbstractCommunication between the brain and peripheral mediators of systemic inflammation is implicated in numerous psychological, behavioral, and physiological processes. Functional neuroimaging studies have identified brain regions that associate with peripheral inflammation in humans, yet there are open questions about the consistency, specificity, and network characteristics of these findings. The present systematic review provides a meta-analysis ...
Source: Neuroscience and Biobehavioral Reviews - July 30, 2018 Category: Neuroscience Source Type: research

Cannabis use and the development of tolerance: a systematic review of human evidence
Publication date: Available online 26 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Marco Colizzi, Sagnik BhattacharyyaAbstractPrevious studies have reported conflicting results in terms of acute effects of cannabis in man. Independently of other factors, such discrepancy may be attributable to the different cannabis use history of study volunteers. It is thought that regular cannabis users may develop tolerance to the effects of acute cannabis administration. Here we systematically review all studies examining the effects of single or repeated cannabinoid administration in man as a function of previo...
Source: Neuroscience and Biobehavioral Reviews - July 27, 2018 Category: Neuroscience Source Type: research

Where in the serotonergic system does it go wrong? Unravelling the route by which the serotonergic system affects feather pecking in chickens
Publication date: Available online 25 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Elske N. de Haas, Jerine A.J. van der EijkAbstractA deficient serotonergic system is associated with psychopathological behaviors in various species, among which, feather pecking (FP) in chickens. Deficiency in the serotonergic system can predispose birds to develop FP, while the serotonergic system has shown to be affected in birds that feather peck. Serotonin (5-HT) can further influence dopamine (DA) activity. Lines with high FP tendency generally have low central 5-HT and DA turnovers at a young age, but high turno...
Source: Neuroscience and Biobehavioral Reviews - July 26, 2018 Category: Neuroscience Source Type: research

Vision dominates audition in adults but not children: A meta-analysis of the Colavita effect
Publication date: Available online 23 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Rebecca J. Hirst, Lucy Cragg, Harriet A. AllenAbstractThe Colavita effect occurs when participants respond only to the visual element of an audio-visual stimulus. This visual dominance effect is proposed to arise from asymmetric facilitation and inhibition between modalities. It has also been proposed that, unlike adults, children appear predisposed to auditory information. We provide the first quantitative synthesis of studies exploring the Colavita effect, combining data from 70 experiments across 14 studies. A mixed...
Source: Neuroscience and Biobehavioral Reviews - July 24, 2018 Category: Neuroscience Source Type: research

Behavioral Tagging: Plausible involvement of PKMζ, Arc and role of neurotransmitter receptor systems
Publication date: Available online 20 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Shruti Vishnoi, Mehar Naseem, Sheikh Raisuddin, Suhel ParvezAbstractThere are many evidences in support of Behavioral Tagging hypothesis that relies on the setting of a learning tag and the synthesis of plasticity related proteins (PRPs). It explains that how a learning tag produced as a result of weak training can be paired up with PRPs that arrive as a result of novelty and consequently lead to long lasting memories. In the following review we have focused on possible involvement of PKMζ, Arc as PRPs and neurotr...
Source: Neuroscience and Biobehavioral Reviews - July 21, 2018 Category: Neuroscience Source Type: research

Mind wandering perspective on ADHD
Publication date: Available online 20 July 2018Source: Neuroscience & Biobehavioral ReviewsAuthor(s): Natali Bozhilova, Giorgia Michelini, Jonna Kuntsi, Philip AshersonAbstractAttention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder associated with a range of mental health, neurocognitive and functional problems. Although the diagnosis is based on descriptions of behaviour, individuals with ADHD characteristically describe excessive spontaneous mind wandering (MW). MW in individuals with ADHD reflects constant mental activity which lacks topic stability and content consistency. Based on t...
Source: Neuroscience and Biobehavioral Reviews - July 21, 2018 Category: Neuroscience Source Type: research