Disrupted default mode network and executive control network are associated with depression severity on structural network
Conclusions
Patients with smaller GMV of ACC.L are more likely to develop severe MDD, and as a key region in both networks which have distinct structural network models in DMN and ECN. MDD patients with different severity have different neuroimaging changes in DMN and ECN. (Source: NeuroReport)
Source: NeuroReport - March 17, 2022 Category: Neurology Tags: Clinical Neuroscience Source Type: research
The effect of the degree and location of danger in traffic hazard perception: an ERP study
Conclusions
The results suggest that hazards are more easily processed in the central visual area during the early stage of automatic perception. In the later hazard evaluation stage, the hazard in the central visual area and the high-hazard situation were more easily processed. (Source: NeuroReport)
Source: NeuroReport - March 17, 2022 Category: Neurology Tags: Clinical Neuroscience Source Type: research
The role of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type receptor modulators in object recognition memory reconsolidation
Conclusion
These findings provide new evidence that the AMPA receptor plays an important role in the reconsolidation phase of ORM. (Source: NeuroReport)
Source: NeuroReport - February 11, 2022 Category: Neurology Tags: Integrative Systems Source Type: research
Effects of Tai Chi Chuan on cortical sources of EEG rhythms in the resting state in elderly individuals: a cross-sectional study
A standard low-resolution electromagnetic tomography (sLORETA) technique was used to observe the effect of long-term Tai Chi Chuan practice on the resting state of the brains of elderly individuals. Eyes-closed resting-state electroencephalography (EEG) signals were collected from 14 long-term Tai Chi Chuan (TCC) elderly practitioners, 14 demographically matched healthy controls (HCs) and 14 healthy young adults (HYs). The EEG rhythms of delta, theta, alpha 1, alpha 2, beta 1 and beta 2 were analyzed. The cortical sources of these EEG rhythms were estimated by sLORETA. The data showed that the theta and alpha 1 brain sourc...
Source: NeuroReport - February 11, 2022 Category: Neurology Tags: Integrative Systems Source Type: research
Neuroprotective effects of N-acetylcysteine amide against oxidative injury in an aging model of organotypic hippocampal slice cultures
Conclusion
Therefore, the neurons that survived due to the neuroprotective effects of NACA also showed enhanced functional activity in long-term cultured OHSCs using electrophysiological and biochemical assays. (Source: NeuroReport)
Source: NeuroReport - February 11, 2022 Category: Neurology Tags: Degeneration and Repair Source Type: research
Language specificity in the processing of affirmative and negative sentences
Conclusion
These results demonstrated the ‘truth reversing hypothesis’. Further analysis revealed the effect of language expression on the neural mechanism of sentential negation. (Source: NeuroReport)
Source: NeuroReport - February 11, 2022 Category: Neurology Tags: Degeneration and Repair Source Type: research
Recombinant human erythropoietin protects long-term cultured ageing primary nerve cells by upregulating the PI3K/Akt pathway
Conclusions
This study explored the relationship between the rhEPO and PI3K/Akt pathways in the protection of ageing nerve cells at the cellular level and found that rhEPO protects long-term cultured ageing primary nerve cells by upregulating the PI3K/Akt pathway. These findings provide a theoretical basis and experimental evidence for the antiaeging mechanism of EPO in the nervous system. (Source: NeuroReport)
Source: NeuroReport - February 11, 2022 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
Circular noncoding RNA circ_0007865, serves as a competing endogenous RNA, targeting the miR-214-3p/FKBP5 axis to regulate oxygen-glucose deprivation-induced injury in brain microvascular endothelial cells
Conclusion
According to these results, circ_0007865 deficiency could attenuate OGD-induced HBMEC damage by modulating the miR-214-3p/FKBP5 axis, hinting at a promising therapeutic target for future acute IS therapy. (Source: NeuroReport)
Source: NeuroReport - February 11, 2022 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
FG7142 combined with restraint stress induces anxiogenic-like effects via downregulation gamma-aminobutyric acid type A receptor subunit alpha1 and 5-hydroxytryptamine 1A receptors expression in the hippocampus
Conclusions
These results indicated that FG7142 combined with restraint stress is sufficient to induce anxiety, and its mechanism is associated with downregulation of hippocampal gamma-aminobutyric acid type A receptor subunit alpha1 and 5-hydroxytryptamine 1A receptors. (Source: NeuroReport)
Source: NeuroReport - February 2, 2022 Category: Neurology Tags: Integrative Systems Source Type: research
The brain state of motor imagery is reflected in the causal information of functional near-infrared spectroscopy
Background
Brain–computer interface (BCI) is a promising neurorehabilitation strategy for ameliorating post-stroke function disorders. Physiological changes in the brain, such as functional near-infrared spectroscopy (fNIRS) dedicated to exploring cerebral circulatory responses during neurological rehabilitation tasks, are essential for gaining insights into neurorehabilitation mechanisms. However, the relationship between the neurovascular responses in different brain regions under rehabilitation tasks remains unknown.
Objective
The present study explores the fNIRS interactions between brain regions under dif...
Source: NeuroReport - February 2, 2022 Category: Neurology Tags: Integrative Systems Source Type: research
An ERP study on the influence of mental abacus calculation on subthreshold arithmetic priming in children
Conclusion
These results yielded insights into the effect of early abacus training on children’s cognitive processing, providing a theoretical basis for the development and promotion of abacus training. (Source: NeuroReport)
Source: NeuroReport - February 2, 2022 Category: Neurology Tags: Integrative Systems Source Type: research
High uric acid induced hippocampal mitochondrial dysfunction and cognitive impairment involving intramitochondrial NF-κB inhibitor α/nuclear factor-κB pathway
Conclusion
The results provided new insights into the mechanism underlying hyperuricemia-related cognitive decline. (Source: NeuroReport)
Source: NeuroReport - February 2, 2022 Category: Neurology Tags: Degeneration and Repair Source Type: research
A new nitronyl nitroxide radical with salicylic acid framework attenuates blood–brain barrier disruption and oxidative stress in a rat model of middle cerebral artery occlusion
Conclusion
Our results suggested that SANR has a neuroprotective effect against cerebral I/R injury, and its effect mechanism is related to the antioxidant function. (Source: NeuroReport)
Source: NeuroReport - February 2, 2022 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
The distinct roles of various neurotransmitters in modulating methamphetamine-induced conditioned place preference in relevant brain regions in mice
Conclusions
These results suggested that the neurotransmitters of DA, Glu and Gln may work together and play important roles in METH-induced CPP in relevant brain reward circuits, especially in PFc and NAc. These findings therefore could help to advance the comprehensive understanding of the neurochemic and psychopharmacologic properties of METH in reward effect, which is important for future improvements in the treatment of drug addiction. (Source: NeuroReport)
Source: NeuroReport - February 2, 2022 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
Disrupted functional connectivity between the nucleus accumbens and posterior cingulate cortex in autism spectrum disorder
Conclusions
This study suggests that the dysconnectivity between the NAcc and PCC may account for social dysfunctions in ASD. (Source: NeuroReport)
Source: NeuroReport - January 16, 2022 Category: Neurology Tags: Integrative Systems Source Type: research
