When Task is Huge but Time is Short! An Interesting Case of Stroke Thrombolysis
Debabrata Chakraborty, Suvadip Maiti, Sadanand Dey, Sanjay BhaumikNeurology India 2023 71(3):552-554 A 64-year-old gentleman, diabetic, and smoker attended the emergency room (ER) with acute stroke. He had expressive aphasia with right upper limb weakness. His blood pressure was extremely high, and he presented in the final half an hour of the permissible window period for thrombolysis. Bringing down his blood pressure to make him eligible for the procedure within the available time was a real challenge for us. Fortunately, we succeeded in our attempt and he gradually improved. Truly, the maximum blood pressure allowable ...
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Debabrata Chakraborty Suvadip Maiti Sadanand Dey Sanjay Bhaumik Source Type: research

Primary Endodermal Sinus Tumor of the Intraspinal Cavity: A Case Report and Review of the Literature
We report a 19-year-old woman who presented with back pain and weakness of both lower extremities who was found to have an EST in the spinal canal cavity. She had severely elevated serum alpha-fetoprotein (AFP) level at presentation. Magnetic resonance imaging (MRI) revealed the mass in the spinal canal. The tumor was excised. Serum AFP returned to normal after three cycles of chemotherapy. We describe the imaging findings and the macroscopic and microscopic features of this rare tumor. EST is a relatively rare malignant germ cell tumor that usually originates in the gonads and has poor prognosis. This is a rare case of th...
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Wenhua Li Yongjie Wang Xiangru Wu Caiting Chu Source Type: research

Soft Palate Malignant Melanoma as an Adverse Effect of Fingolimod in Multiple Sclerosis: A Case Report and Literature Review
Hossein Mozhdehipanah, Farshid Safdarian, Sepideh PaybastNeurology India 2023 71(3):546-548 Fingolimod has been approved as a disease-modifying drug in multiple sclerosis since 2010. There are a few reports of melanoma as a side effect of Fingolimod in the literature. Herein we aim to report a known case of multiple sclerosis under Fingolimod presenting with persistent nasal congestion who was eventually diagnosed with soft palate malignant melanoma. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Hossein Mozhdehipanah Farshid Safdarian Sepideh Paybast Source Type: research

The Journey and Progress of the Department of Neurosurgery at the University College of Medical Sciences and Guru Teg Bahadur Hospital
Conclusion: The department right now is providing satisfactory patient care with absolutely no financial burden to the patients. Neurosurgery academic residency has recently resumed, and a wide range of neurosurgical conditions are being successfully treated. If the existing challenges are addressed in a timely manner, the coming years hold a bright future for the department. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Pragyan Sarma Source Type: research

Cross-Cultural Teachings from Cremation Practices: Atmaram for the Departed, Shiva Linga for the Living, and Odontoid Fracture for the Neurosurgeons!
Deepak K Gupta, Anna T MazzeoNeurology India 2023 71(3):536-538 Atmaram bone ( C2 axis vertebra) is usually handed over to the family of the deceased on the next day after cremation during the ''Asthi sanchaya '' commemoration. ''Asthi visarajan'' involves the practice of immersing the bones and ashes of the deceased in the Holy Ganges river as per Hindu beliefs. Atmaram bone, which usually does not burn during cremation, is handed over to the family of the departed ( asthi sanchaya ) after cremation which is then immersed in the holy ...
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Deepak K Gupta Anna T Mazzeo Source Type: research

Acute Toxic Encephalopathy in Occupational Exposure with Polyvinyl Chloride (PVC) Fumes: A Case Series
Conclusion: Early suspicion and aggressive management can have favorable outcome in PVC toxic encephalopathy. Occupational hazards due to PVC toxicity are increasing in the present industrial era but it is very less identified. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Rajesh Verma Rajarshi Chakraborty Prithvi Giri Source Type: research

Introduction of Spring-Assisted Cranioplasty for Bicoronal Synotosis in India: Description of First Case and Our Learning Experience
Conclusion: Spring-assisted cranioplasty for bicoronal synostosis is a safe and elegant technique, is less invasive than many other cranioplasties, and results in marked improvement in the calvarial shape. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Debarati Chattopadhyay Madhubari Vathulya Akshay Kapoor Rajnish Arora Source Type: research

Postoperative Third Nerve Palsy after Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenoma: Elucidating its Mechanism
Facundo Villamil, Guido Caffaratti, Mauro E Ruella, Sebastian J M Giovannini, Andres CervioNeurology India 2023 71(3):522-526 Third nerve palsy is a rare complication of transsphenoidal surgery and has been merely mentioned in different studies, but there is not any rigorous analysis focusing on this particular complication. The purpose of this study is to analyze this complication after transsphenoidal surgery for a pituitary adenoma to better understand its pathophysiology and outcome. The authors retrospectively analyzed 3 cases of third nerve palsy selected from the 377 patients operated via a transsphenoidal route be...
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Facundo Villamil Guido Caffaratti Mauro E Ruella Sebastian J M Giovannini Andres Cervio Source Type: research

Rivastigmine for Cognitive Impairment in Multiple Sclerosis: A Prospective Randomized Open Label study with Blinded End-Point Assessment
Conclusion: Rivastigmine is safe and effective in improving memory functions in cognitively impaired MS patients. However, our study has a small sample size and tested only a single domain. Larger studies with a validated single comprehensive neuropsychological test are needed. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Amrita J Gotur Kameshwar Prasad Rohit Bhatia Achal K Srivastava Manjari Tripathi Vinay Goyal Awadh K Pandit Deepti Vibha Roopa Rajan MV Padma Srivastava Source Type: research

Magnetization Transfer Contrast & #8211; Is it Sensitive Enough to Differentiate Demyelination from Axonal Loss ?
Conclusions: MTR is a sensitive technique to identify neuronal injury, whether it is DM or AL. It, however, cannot differentiate these two pathological processes. MTR is not sensitive to identify acute ON. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Joga Chaganti Hannah Woodford Michael Taylor Sai Sivananda Chaganti Alexandra Louise MacDonald Raymond Garrick Source Type: research

Primary Intracranial Germ Cell Tumors: A Study with an Integrated Clinicopathological Approach
Conclusions: Analysis of our largest single cancer center Indian patient cohort of ICGCT shows that inclusion of age ≤6 years, raised TM, and certain radiological features may assist clinicians in overcoming the limitations of surgical sampling, with better prognostication of histologically diagnosed germinomas. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Ayushi Sahay Sridhar Epari Girish Chinnaswamy Abhishek Chatterjee Jayant Sastri Goda Vijay Patil Aliasgar Moyiadi Prakash Shetty Vikas Singh Arpita Sahu Amit Choudhary Amit Janu Tejpal Gupta Source Type: research

Cervical Discometry: A Useful Technique for an Anterior Cervical Discectomy and Fusion
Conclusions: The intraoperative intervertebral disc pressure measurement could effectively monitor the vertebral body distraction strength and reduce the incidence of postoperative AS and ASD. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Long Yu Xu Cui Da Bao Source Type: research

Volume of Aneurysmal Subarachnoid Hematoma Measured Quantitatively by 3D Slicer to Predict Symptomatic Cerebral Vasospasm
Conclusions: Volume of aneurysmal subarachnoid hematoma measured quantitatively by 3D Slicer can improve the predictive value for symptomatic cerebral vasospasm. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Huang Yanming Lai Xiaoyan Guan Celin Qi Xiaolong Li Huihua Lin Xin Que Shuanglin Source Type: research

fMRI Analysis of Dissociative Convulsions: A Case-Controlled Study
Conclusions: Patients with dissociative convulsions have significant deficits in the areas associated with the processing of emotional, cognitive, memory, and sensory-motor functions. There is a significant correlation between dissociative severity and the functioning of areas involving the processing of emotions, cognition, and memory. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Harshit Garg Pratap Sharan Senthil S Kumaran Rachna Bhargava Bichitra N Patra Manjari Tripathi Source Type: research

Analysis of Risk Factors for Epilepsy after Combined Re-Vascularization in Adult Patients with Moyamoya Disease
Conclusions: Pre-operative epilepsy, the location of the bypass recipient artery, new cerebral infarction, hyper-perfusion syndrome, and intra-cranial hemorrhage may have a causal relationship with epilepsy in adult MMD patients. It is suggested that some risk factors could be intervened to reduce the incidence of post-operative epilepsy in MMD patients. (Source: Neurology India)
Source: Neurology India - June 15, 2023 Category: Neurology Authors: Erheng Liu Lide Jin Weihua Tao Xueyi Tan Chengyuan Liu Shuai Zhou Shengquan Huang Xiying Qian Jianhua Zhao Xuehua Li Shuaifeng Yang Source Type: research