Neurology(R) Clinical Practice: Laying a Foundation to Become the Primary Home for Quality-Oriented Research in Neurology
What a year! Saying that my first 12 months as the Editor of Neurology® Clinical Practice (NCP) have been very exciting would be an understatement. In October 2021, at the height of the pandemic, we embarked on a major editorial transition, starting with the establishment of a new team of unique leaders to represent NCP and guide us in our new vision. After having worked together for a year, I can say that the energy, innovation, and drive that this team brings to the journal is awe-inspiring. Shaping a new vision for a scientific journal is truly a journey, and one that must be tackled with out-of-the-box thinkers: (S...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Bartolini, L. Tags: Special Editorial Source Type: research
Intracranial Corkscrew Angiopathy
We present a young woman who presented with a thunderclap headache, found to have a nonaneurysmal SAH.
Results
Cerebral angiogram revealed corkscrew angiopathy in medium-sized vessels and multiple micro-occlusions with collateralization. No intracranial aneurysm was detected. Extensive workup for vasculitis and genetic causes for vasculopathy was unrevealing. The patient had no neurologic deficits, and her symptoms resolved.
Discussion
This is an extremely rare presentation of subarachnoid hemorrhage due to corkscrew angiopathy. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Lalla, R., Virmani, D., Suchdev, K., Peeler, C. E., Abdalkader, M., Nguyen, T. N. Tags: Clinical/Scientific Note Source Type: research
Clinical Profile and Outcomes of COVID-19-Associated Transverse Myelitis: A Case Report and Review of Literature
Purpose of Review
The purpose of this study was to evaluate demographics, clinical profiles, and outcomes of transverse myelitis (TM) in the setting of COVID-19 infection (iTM) or vaccination (vTM) and to describe a case of spontaneous resolution of iTM.
Recent Findings
Of a total of 158 articles that met our search criteria, 30 articles detailing 65 unique cases were included, of which 48 (73.8%) were iTM and 17 (26.2%) were vTM. The mean age of the iTM group was significantly lower as compared with vTM (43 ± 20.3 years vs 56.4 ± 18.6 years; p = 0.02). There were no gender differences between the groups. Th...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Gudlavalleti, A., Nath, A. Tags: Review Source Type: research
Systematic Review of Accelerated Long-term Forgetting in Children and Adolescents With Neuropediatric Diseases
Purpose of Review
Accelerated long-term forgetting (ALF) describes the phenomenon of normal learning and memory performance after short delays, but greater forgetting after longer delays, which is not objectified in standardized memory tests. The topic is attracting increasing interest due to its clinical importance. Studies investigating pediatric ALF remain rare, and no systematic review exists.
Recent Findings
Based on our systematic literature search, 12 studies were found. Although most studies investigated ALF in children with epilepsy (n = 9), there is also evidence of ALF in children after traumatic brain injury (...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Stähli, N. E., Bigi, S., Grunt, S., Lidzba, K., Studer, M. Tags: Review Source Type: research
Feasibility and Acceptability of a Multidisciplinary Academic Telemedicine System for Memory Care in Response to COVID-19
We present data as descriptive statistics and comparisons using Wilcoxon rank-sum tests and Fisher exact tests. The results of anonymous surveys conducted among the clinic's providers are reported as descriptive findings.
Results
After the implementation of telemedicine services, the proportion of clinic encounters completed via VTC increased from 1.9% to 86.4%. There was a statistically significant decline in both the percentage of scheduled appointments that were canceled (32.9% vs 27.9%; p < 0.01) and total cancelations per month (mean 240.3 vs 179.4/mo; p < 0.01). There was an increase in the percentage of compl...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Rini, J. F., Tsoy, E., Peet, B., Best, J., Tanner, J. A., Asken, B. M., Sanchez, A., Apple, A. C., VandeVrede, L., Stephens, M. L., Erkkinen, M., Kramer, J. H., Miller, B. L. Tags: Research Article Source Type: research
Self-Reported Severity and Causes of Traumatic Brain Injury in Patients With Epileptic or Functional Seizures
Discussion
Our findings further the association of mild TBI with FS and prompt reconsideration of typical assumptions regarding the significance of a reported TBI history in patients with previously undifferentiated seizures. Although common in both groups, TBI with LOC less than 30 minutes and causes of injury that are commonly believed to be more severe were reported more frequently in FS than ES. This suggests that a patient or caregiver reporting of these features does not imply that PTE is a more probable diagnosis than FS. Although a history of TBI with LOC and presumed high-risk causes of injury intuitively raises s...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Hickman, L. B., Patel, A. B., Dubey, I., Karimi, A. H., Zhang, X., Janio, E. A., Allas, C. H., Sreenivasan, S. S., Bauirjan, J., D'Ambrosio, S., Al Banna, M., Cho, A. Y., Engel, J., Stern, J. M., Kerr, W. T. Tags: Research Article Source Type: research
Inpatient Teleneurology Follow-up Has Comparable Outcomes to In-Person Neurology Follow-up
Discussion
Teleneurology follow-up resulted in comparable outcomes to in-person neurology follow-up, with few transfers after admission. For select neurology and ischemic stroke patients, teleneurology follow-up provides an alternative to transfer for hospitals lacking neurology coverage. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Zha, A. M., Trevino, A. D., Ankrom, C. M., Chu, K. M., Joseph, M. M., Patni, T., Cossey, T. D., Savitz, S. I., Wu, T.-C., Jagolino-Cole, A. Tags: Research Article Source Type: research
Humanistic Burden of Huntington Disease: Evidence From the Huntington Disease Burden of Illness Study
Discussion
The HDBOI study provides new insights into the characteristics and humanistic burden of PwHD and offers a meaningful contribution to this underserved research area. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Rodriguez Santana, I., Frank, S., Doherty, M., Willock, R., Hamilton, J., Hubberstey, H., Stanley, C., Vetter, L., Winkelmann, M., Dolmetsch, R. E., Li, N., Ratsch, S., Ali, T. M. Tags: Research Article Source Type: research
Physical Functional Impairment and the Risk of Incident Mild Cognitive Impairment in an Observational Study of World Trade Center Responders
The objective of this prospective cohort study was to examine whether PFI was associated with increased risk of incident mild cognitive impairment (MCI) among World Trade Center (WTC) responders with PTSD. We hypothesized that responders with PTSD would have an elevated risk of incident MCI and that PFI would mediate this increase.
Methods
We examined responder participants in the WTC Aging Study whose baseline physical assessments were completed by May 2016–April 2017 and were followed up at least once before December 2019. Those without complete demographic, medical, or behavioral data were excluded. PFI was asses...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Pellecchia, A., Kritikos, M., Guralnik, J., Ahuvia, I., Santiago-Michels, S., Carr, M., Kotov, R., Bromet, E. J., Clouston, S. A. P., Luft, B. J. Tags: Research Article Source Type: research
Acute Symptomatic Seizure Associated With Chronic Antiseizure Medication Use After Stroke
Discussion
Chronic ASM use is highly associated with electrographic, rather than convulsive, ASyS. However, long-term ASM use is independently associated with PSE and its risk factors, including convulsive ASyS. With the ubiquity of stroke-related ASyS concerns in routine clinical practice, comparative effectiveness studies to guide ASM management are needed. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Byrnes, M., Chandan, P., Newey, C., Hantus, S., Punia, V. Tags: Research Article Source Type: research
NeuroMeasures--Implementation of a Web-Based, Real-Time Quality Metric Tool to Improve Provider Practices in an Epilepsy Clinic
Discussion
A web-based point-of-care EQM application demonstrated significant improvement of the HCP's ability to perform and review EQMs at the point-of-care patient visit. Furthermore, the application was successful in creating opportunities for direct intervention based on the EQMs and chances for better patient education and provider-patient communication. Further considerations would include automated survey requests and expansion into other AAN QMs. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Syed, M. J., Marawar, R., Basha, M. M., Zutshi, D. Tags: Research Article Source Type: research
Telemedicine Utilization Among Patients With Multiple Sclerosis in the US Veterans Health Administration, 2010-2020
The objective of this study is to assess the frequency and longitudinal patterns of telemedicine utilization among PwMS and controls.
Methods
We conducted a population-based nested case-control study within the Veterans Health Administration (VHA) from January 1, 2010, to December 31, 2020. MS cases and controls were individually matched on sex, age, and Veterans Affair (VA) service region (Veterans Integrated Service Network). MS case and control participants sample sizes by year included 2010: 19,387/86,379; 2016: 19,752/88,535; and 2020: 16,451/78,315. Telemedicine encounter codes were used to identify telemedicine uti...
Source: Neurology Clinical Practice - December 13, 2022 Category: Neurology Authors: Abdel Magid, H. S., Jin, S., Culpepper, W. J., Nelson, L. M., Wallin, M. Tags: Research Article Source Type: research
Coordination of Care Among Physical Therapists and Neurologists in Huntington Disease
This study presents a framework for physical therapy through the course of Huntington disease (HD) which includes coordinated care plans with neurologists. HD is an inherited neurodegenerative disorder that leads to impaired strength and coordination and ultimately progressive loss of function. Interdisciplinary HD care teams provide patient-centered, comprehensive evaluations and make recommendations for pharmacologic, healthcare, and lifestyle interventions based on best available evidence. Physical therapists work to improve movement and mobility using specific therapeutic interventions and individualized exercise progr...
Source: Neurology Clinical Practice - October 11, 2022 Category: Neurology Authors: Fritz, N. E., Kegelmeyer, D., Rao, A. K., Quinn, L., Nance, M. A., Kloos, A. Tags: Commentary Source Type: research
Creating a Patient-Based Diagnostic Checklist for Functional Tics During the COVID-19 Pandemic
This study confirms the presence of a distinct presentation of aTT during the pandemic period. It further establishes the validity of specific criteria useful in dividing patients with tics into 3 formal diagnostic criteria: (1) primary tic disorders (PTDs), (2) a strictly FTD, and (3) a mixed tic disorder consisting of patients with an initial history of a PTD and the later development of FT. Explicit diagnostic criteria should enable clinicians and researchers to make a definitive identification and assist patients and families become more knowledgeable and accepting of the diagnosis of FT. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - October 11, 2022 Category: Neurology Authors: Trau, S. P., Quehl, L., Tsujimoto, T. H. M., Lin, F.-C., Singer, H. S. Tags: Research Article Source Type: research
Objective Neurophysiologic Markers of Cognition After Pediatric Brain Injury
Discussion
Despite heterogeneity of brain injuries and brain development, our objective EEG markers reflected cognitive recovery independent of motor function. Two of these markers required no active participation. Together, they allowed us to identify 3 individuals who meet the criteria for cognitive-motor dissociation. To diagnose, prognose, and track cognitive recovery accurately, such markers should be used in pediatrics. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - October 11, 2022 Category: Neurology Authors: Kim, N., Watson, W., Caliendo, E., Nowak, S., Schiff, N. D., Shah, S. A., Hill, N. J. Tags: Research Article Source Type: research
