Adverse Childhood Experiences in Patients With Neurologic Disease
Discussion
Patients with neurologic conditions are more likely to have high ACEs than the US population, which was associated with higher rates of health care utilization, increased number of medical and psychiatric comorbidities, and higher anxiety and depression scores. Addressing ACEs may be a way to improve the health outcomes of patients with neurologic conditions. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Mendizabal, A., Nathan, C. L., Khankhanian, P., Anto, M., Clyburn, C., Acaba-Berrocal, A., Breen, L., Dahodwala, N. Tags: All Health Services Research, Outcome research, Structural and social determinants of health, Case control studies Source Type: research
EEG Abnormalities and Their Radiographic Correlates in a COVID-19 Inpatient Cohort
This article highlights the range of EEG abnormalities frequently associated with acute neuroimaging abnormalities in COVID-19. Mortality rates were high, particularly for patients in coma requiring mechanical ventilation. These findings may guide the prognosis and management of patients with COVID-19 and neurologic changes. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Hwang, S. T., Ballout, A. A., Sonti, A. N., Kapyur, A., Kirsch, C., Singh, N., Markowitz, N., Leung, T. M., Chong, D. J., Temes, R., Pacia, S. V., Kuzniecky, R. I., Najjar, S. Tags: All Imaging, Coma, COVID-19, All Epilepsy/Seizures, EEG Research Source Type: research
COVID-19 Outcomes in Hospitalized Patients With Neurodegenerative Disease: A Retrospective Cohort Study
Discussion
We found that there was no difference in short-term mortality of patients with ND hospitalized for COVID-19 compared with CL, but they may have higher rates of neurologic complications and disability. Future studies should address long-term outcomes. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Patel, R. A., Stebbins, G. T., Kishen, E. B., Barton, B. Tags: Outcome research, Parkinson's disease/Parkinsonism, All Cognitive Disorders/Dementia, COVID-19, Cohort studies Source Type: research
Association Between Pharmacy Benefit Restrictions and Disease-Modifying Therapy Use in the Medicare Part D Program
Discussion
Medicare beneficiaries with MS enrolled in restrictive Part D plans were less adherent to their DMT and had higher rates of MS-related outpatient visits. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Hartung, D. M., Johnston, K. A., McGregor, J. C., Bourdette, D. N. Tags: Insurance, Multiple sclerosis Research Source Type: research
Skin Autoimmunity Secondary to Alemtuzumab in a Tertiary Care Spanish Hospital
Discussion
The lesions described are secondary to autoimmune disorders, probably related to immune dysregulation because of a differential lymphocyte repopulation after ALZ. Autoimmune cutaneous AEs may be frequent, and it would be recommended to monitor its appearance to treat them. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Lopez Ruiz, R., Sanchez Fernandez, F., Ruiz de Arcos, M., Dotor Garcia-Soto, J., Fuerte Hortigon, A., Navarro Mascarell, G., Ruiz Pena, J. L., Paramo Camino, M. D., Guerra Hiraldo, J. D., Eichau, S. Tags: Autoimmune diseases, Clinical neurology examination, All Practice Management, Multiple sclerosis Research Source Type: research
Use of Transcranial Doppler as a Biomarker of CAR T Cell-Related Neurotoxicity
Discussion
Our study demonstrates an association between increase in TCD MFV and the development of neurotoxicity, as well as timing of neurotoxicity onset. We believe that TCD ultrasound may be used as a bedside functional biomarker in CAR T-cell patients and may guide immunologic interventions to manage toxicity in this complex patient group. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Holroyd, K. B., Rubin, D. B., LaRose, S., Monk, A., Nikiforow, S., Jacobson, C., Vaitkevicius, H. Tags: Research Source Type: research
Advance Directive and POLST Documentation in Decedents With Dementia at a Memory Care Center: The Importance of Early Advance Care Planning
Discussion
ACP is underutilized in people with dementia, even among those seen in a specialty memory care center. ACP should be introduced early on for people with dementia to ensure patients have a voice in their care. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Naasan, G., Boyd, N. D., Harrison, K. L., Garrett, S. B., D'Aguiar Rosa, T., Perez-Cerpa, B., McFarlane, S., Miller, B. L., Ritchie, C. S., on behalf of the GBHI Dementia Geriatric Palliative Care Writing Group Tags: Decision analysis, Medical care, All Clinical Neurology, Cohort studies, Risk factors in epidemiology Research Source Type: research
Primitive Reflexes and Dementia in Adults With Down Syndrome
Discussion
The presence of multiple reflexes serves as an indicator of dementia status in DS as a supplement to direct assessment of cognition and praxis. The reflex examination may serve as a tool in the multimethod evaluation for dementia in DS, as it appears unaffected by intellectual disability and language mastery. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Harp, J., Koehl, L., Van Pelt, K., Head, E., Jicha, G., Robertson, W., Lightner, D., Lott, I., Schmitt, F. Tags: Clinical neurology examination, All Neuropsychology/Behavior, Developmental disorders, All Cognitive Disorders/Dementia Research Source Type: research
Inpatient vs Outpatient Evaluation of Suspected Paraneoplastic Cerebellar Degeneration
(Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Tags: Correction Source Type: research
Global Advocacy in Action: World Brain Day 2021 Dedicated to Stopping Multiple Sclerosis
World Brain Day (WBD), this year celebrated on July 22, 2021, ushers in a major global advocacy campaign of the World Federation of Neurology (WFN) extending over several months. The first WBD was held in 2014. Since then, WBD has become the largest global event for advocacy of brain health and awareness, with more than 50 million people joining the campaign annually.1-3 (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Wijeratne, T., Jones, E. C., Grisold, W., Carroll, W. M. Tags: Access to care, Public health, Multiple sclerosis Special Editorial Source Type: research
Red Desaturation Prevalence and Severity in Healthy Patients
This study shows that nearly a quarter of healthy patients without apparent optic nerve or macular dysfunction may recognize red desaturation. This deserves consideration when interpreting red desaturation testing in patients suspected to have unilateral optic neuropathy. Further research with larger sample sizes may identify predictors of red desaturation in healthy patients, establish the red desaturation threshold separating pathologic from physiologic phenomena, and assess the repeatability of red desaturation over time in affected individuals. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Mikolajczyk, B., Ritter, A., Larson, C., Connett, J., Olson, J., McClelland, C., Lee, M. S. Tags: Clinical neurology examination, Optic neuritis; see Neuro-ophthalmology/Optic Nerve, Prevalence studies Research Source Type: research
Caring for Individuals With Intellectual and Developmental Disabilities in the COVID-19 Crisis
(Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Tags: Corrections Source Type: research
Adult-Onset Dystonia With Marfanoid Feature
(Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Tags: Corrections Source Type: research
Neurofilament Light Chain Is Related to Longitudinal Decline in Frontotemporal Lobar Degeneration
In the Research article "Neurofilament Light Chain Is Related to Longitudinal Decline in Frontotemporal Lobar Degeneration" by Zhang et al.,1 the data in the third column of Table 4 labeled "F letter fluency" were incorrect. A corrected Table 4 is below. The authors regret the error. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Tags: Corrections Source Type: research
Isolated Occipital Neuralgia as a Relapse of Neuromyelitis Optica
Consider secondary causes of occipital neuralgia, including cervical demyelination, particularly in those with neuromyelitis optica. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Martin, A., Garcia, M. C. Tags: All Headache, Secondary headache disorders, Neuropathic pain, All Demyelinating disease (CNS), Devic's syndrome Case Source Type: research
