Global Advocacy in Action: World Brain Day 2021 Dedicated to Stopping Multiple Sclerosis
World Brain Day (WBD), this year celebrated on July 22, 2021, ushers in a major global advocacy campaign of the World Federation of Neurology (WFN) extending over several months. The first WBD was held in 2014. Since then, WBD has become the largest global event for advocacy of brain health and awareness, with more than 50 million people joining the campaign annually.1-3 (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Wijeratne, T., Jones, E. C., Grisold, W., Carroll, W. M. Tags: Access to care, Public health, Multiple sclerosis Special Editorial Source Type: research
Red Desaturation Prevalence and Severity in Healthy Patients
This study shows that nearly a quarter of healthy patients without apparent optic nerve or macular dysfunction may recognize red desaturation. This deserves consideration when interpreting red desaturation testing in patients suspected to have unilateral optic neuropathy. Further research with larger sample sizes may identify predictors of red desaturation in healthy patients, establish the red desaturation threshold separating pathologic from physiologic phenomena, and assess the repeatability of red desaturation over time in affected individuals. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - February 8, 2022 Category: Neurology Authors: Mikolajczyk, B., Ritter, A., Larson, C., Connett, J., Olson, J., McClelland, C., Lee, M. S. Tags: Clinical neurology examination, Optic neuritis; see Neuro-ophthalmology/Optic Nerve, Prevalence studies Research Source Type: research
Caring for Individuals With Intellectual and Developmental Disabilities in the COVID-19 Crisis
(Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Tags: Corrections Source Type: research
Adult-Onset Dystonia With Marfanoid Feature
(Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Tags: Corrections Source Type: research
Neurofilament Light Chain Is Related to Longitudinal Decline in Frontotemporal Lobar Degeneration
In the Research article "Neurofilament Light Chain Is Related to Longitudinal Decline in Frontotemporal Lobar Degeneration" by Zhang et al.,1 the data in the third column of Table 4 labeled "F letter fluency" were incorrect. A corrected Table 4 is below. The authors regret the error. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Tags: Corrections Source Type: research
Isolated Occipital Neuralgia as a Relapse of Neuromyelitis Optica
Consider secondary causes of occipital neuralgia, including cervical demyelination, particularly in those with neuromyelitis optica. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Martin, A., Garcia, M. C. Tags: All Headache, Secondary headache disorders, Neuropathic pain, All Demyelinating disease (CNS), Devic's syndrome Case Source Type: research
Reversal of Acute Spinal Cord Ischemia by Intravenous Thrombolysis
Systemic thrombolysis may be considered as treatment in acute spinal cord ischemia. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Focke, J. K., Seitz, R. J. Tags: MRI, DWI, Spinal cord infarction Case Source Type: research
Cerebral Venous Sinus Thrombosis With Severe Thrombocytopenia: A Fatal Adverse Event After Johnson & Johnson COVID-19 Vaccination
A high index of suspicion is required to identify the very rare case of CVST after vaccination with an adenovirus vector SARS-CoV-2 vaccine. Headache is very common after vaccination. Onset is within 24 hours. However, headache related to CVST starts 5–7 days after vaccination. This distinction can help clinicians risk stratify headache after SARS-CoV-2 vaccine administration. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Ali, M., Goshgarian, C., Jameson, A. Tags: COVID-19, Cerebral venous thrombosis Case Source Type: research
Waxing and Waning Neuroimaging Abnormalities in Langerhans Cell Histiocytosis
In adult Langerhans cell histiocytosis, progressive and accumulating imaging lesions in the CNS can regress. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: McCarron, L. V., Kelly, P., McConville, C., Flynn, P., McCarron, M. O. Tags: MRI, All Clinical Neurology, Endocrine, All Oncology Case Source Type: research
Progressive and Fatal Brainstem Stroke in Systemic Giant Cell Arteritis
A 74-year-old woman presented with acute worsening of a 6-month long history of vertigo and postural instability with MRI evidence of cerebellar and brainstem acute infarcts. Extensive neurovascular assessment revealed a severe vascular damage with multiple stenoses and occlusions along the vertebrobasilar axis (Figure 1). Duplex ultrasonography showed hypoechoic halo sign along facial artery, whereas PET-CT highlighted increased fluorine-18-fluorodeoxyglucose uptake along vertebral and other larger arteries, thus allowing a diagnosis of giant cell arteritis (Figure 2).1,2 Despite prompt treatment with high-dose steroids a...
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Poretto, V., Piffer, S., Bignamini, V., Tranquillini, E., Donner, D., Cavatorta, F. P., Barbareschi, M., Petralia, B., Giometto, B. Tags: MRI, PET, Ultrasound, Vasculitis Case Source Type: research
Catastrophic Cerebral Fat Embolism Syndrome Lacks Hyperacute MRI Findings
In patients who experience stroke due to cerebral fat embolism, hyperacute MRI may lack the characteristic diffusion-weighted imaging/fluid-attenuated inversion recovery changes expected in acute ischemic stroke. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Gusler, M. T., Vagal, A., Gilday, S. D., Flaherty, M. L. Tags: Stroke in young adults, MRI, Other cerebrovascular disease/ Stroke, Hematologic, Embolism Case Source Type: research
Caveats to Acute Imaging for Acute Stroke in the Setting of Venoarterial Extracorporeal Membrane Oxygenation
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for cardiorespiratory support in medically refractory cases. The high rate of neurologic complications, specifically cerebrovascular disorders such as acute ischemic stroke, in VA-ECMO patients frequently prompts the acquisition of neuroimaging studies such as CT with angiography and perfusion imaging. Clinicians must be familiar with the ECMO-related artifacts when interpreting such studies. Here, we describe a case of asymmetric contrast opacification in a VA-ECMO patient with axillary artery cannulation. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Viamonte, M. A., Yu, J., Echevarria, F. D., Nagae, L., Youn, T. S., Tahsili-Fahadan, P., Simpkins, A. N. Tags: Stroke in young adults, CT, All Cerebrovascular disease/Stroke Case Source Type: research
Selective Dysarthria Due to Clival Chordoma
Selective dysarthria is unusual and requires evaluation of other etiologies in addition to vascular ones (mainly pathology of the oral cavity or brainstem). (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Perez-Lopez, C., Abenza-Abildua, M. J., Rodriguez-Dominguez, V., Gonzalez-Martin, L., Hernandez-Garcia, B. J. Tags: Primary brain tumor Case Source Type: research
Amyloid-PET-Positive Patient With bvFTD: Wrong Diagnosis, False Positive Scan, or Copathology?
Positive amyloid PET does not exclude FTD pathology in the diagnostic workup of dementia patients. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Langheinrich, T., Kobylecki, C., Jones, M., Thompson, J. C., Snowden, J. S., Hinz, R., Pickering-Brown, S., Mann, D., Roncaroli, F., Herholz, K., Gerhard, A. Tags: Diagnostic test assessment, PET, Alzheimer's disease, Frontotemporal dementia, Assessment of cognitive disorders/dementia Case Source Type: research
Subacute CNS Demyelination After Treatment With Immune Checkpoint Inhibitors
In a patient who develops neurologic symptoms while taking immune checkpoint inhibitors such as pembrolizumab, do consider CNS demyelination as a differential diagnosis. (Source: Neurology Clinical Practice)
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Tan, E., Shaw, H., Nathan, P., Ghosh-Ray, S., Ottaviani, D. Tags: MRI, All Clinical Neurology, All Oncology, All Demyelinating disease (CNS) Case Source Type: research
