Low Fluctuation of Symptoms May Delay Diagnosis of Myasthenia Gravis: A Case Series
ConclusionWhile the typical clinical pattern of myasthenia gravis is well known and easily recognizable, there are cases when the diagnosis, and thus the treatment, is delayed because of low or absent fluctuation of symptoms. The acknowledgment of this probably underestimated presentation is important for expeditious management. (Source: Neurology and Therapy)
Source: Neurology and Therapy - December 18, 2021 Category: Neurology Source Type: research
Real-World Adherence to Tetrabenazine or Deutetrabenazine Among Patients With Huntington ’s Disease: A Retrospective Database Analysis
ConclusionsResults from this real-world analysis indicate that patients treated with deutetrabenazine are more adherent to treatment and have lower discontinuation rates compared with patients in the tetrabenazine cohort. However, a potential limitation is overestimated adherence, as claims for prescription fills may not capture actual use. Additional research is warranted to explore the differences in adherence patterns between treatments, which may inform treatment decision-making. (Source: Neurology and Therapy)
Source: Neurology and Therapy - December 14, 2021 Category: Neurology Source Type: research
Migraine and Ischemic Stroke: A Mendelian Randomization Study
ConclusionsBy conducting a series of causal inference approaches, this study supports no causal effect of migraine on ischemic stroke and its subtypes. (Source: Neurology and Therapy)
Source: Neurology and Therapy - December 13, 2021 Category: Neurology Source Type: research
Erenumab Decreases Headache-Related Sick Leave Days and Health Care Visits: A Retrospective Real-World Study in Working Patients with Migraine
ConclusionsThe results of this registry study suggest that in addition to the effect on the monthly number of migraine days documented in clinical trials, erenumab can significantly reduce the number of headache-related sick leave days and health care visits in employed patients with migraine managed in routine clinical practice. (Source: Neurology and Therapy)
Source: Neurology and Therapy - December 10, 2021 Category: Neurology Source Type: research
Burden of Migraine in Japan: Results of the ObserVational Survey of the Epidemiology, tReatment, and Care Of MigrainE (OVERCOME [Japan]) Study
ConclusionIn Japan, the burden of migraine and barriers to migraine care are substantial. Improving patient awareness and healthcare provider vigilance may help improve patient outcomes. (Source: Neurology and Therapy)
Source: Neurology and Therapy - December 3, 2021 Category: Neurology Source Type: research
