Reviewer lists for Neuro-Oncology
(Source: Neuro-Oncology)
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Tags: List of reviewers Source Type: research
Systemic therapy of brain metastases: non-small cell lung cancer, breast cancer, and melanoma
Brain metastases (BM) occur frequently in many cancers, particularly non–small cell lung cancer (NSCLC), breast cancer, and melanoma. The development of BM is associated with poor prognosis and has an adverse impact on survival and quality of life. Commonly used therapies for BM such as surgery or radiotherapy are associated with only modest benefits. However, recent advances in systemic therapy of many cancers have generated considerable interest in exploration of those therapies for treatment of intracranial metastases.
This review discusses the epidemiology of BM from the aforementioned primary tumors and the chal...
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Authors: Chamberlain, M. C., Baik, C. S., Gadi, V. K., Bhatia, S., Chow, L. Q. M. Tags: Review Source Type: research
Message from the Editor-in-Chief
(Source: Neuro-Oncology)
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Authors: Wen, P. Y. Tags: Editorial Source Type: research
Contents_Page
(Source: Neuro-Oncology)
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Subscriptions
(Source: Neuro-Oncology)
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Editorial_Board
(Source: Neuro-Oncology)
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Cover
(Source: Neuro-Oncology)
Source: Neuro-Oncology - December 26, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Announcements
(Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Tags: Announcements Source Type: research
Response to "Glioma resection and tumor recurrence: back to Semmelweis"
(Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Menei, P., Clavreul, A., Lemee, J. M. Tags: Reply to Letter Source Type: research
Glioma resection and tumor recurrence: back to Semmelweis
(Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Ratel, D., van der Sanden, B., Wion, D. Tags: Letter to the Editor Source Type: research
Multimodal imaging patterns predict survival in recurrent glioblastoma patients treated with bevacizumab
Conclusion
With the use of machine learning techniques to analyze imaging features derived from pre- and posttherapy multimodal MRI, we were able to develop a predictive model for patient OS that could potentially assist clinical decision making. (Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Chang, K., Zhang, B., Guo, X., Zong, M., Rahman, R., Sanchez, D., Winder, N., Reardon, D. A., Zhao, B., Wen, P. Y., Huang, R. Y. Tags: Clinical Investigation Source Type: research
Clinical parameters outweigh diffusion- and perfusion-derived MRI parameters in predicting survival in newly diagnosed glioblastoma
Conclusions
MRI parameters help to predict OS in a univariate Cox regression analysis, and increased rCBVCE is associated with shorter PFS in the multivariable model. In summary, however, our findings suggest that the relevance of MRI parameters is outperformed by clinical parameters in a multivariable analysis, which limits their prognostic value for survival prediction at the time of initial diagnosis. (Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Burth, S., Kickingereder, P., Eidel, O., Tichy, D., Bonekamp, D., Weberling, L., Wick, A., Löw, S., Hertenstein, A., Nowosielski, M., Schlemmer, H.-P., Wick, W., Bendszus, M., Radbruch, A. Tags: Basic and Translational Investigation Source Type: research
Frequent occurrence of therapeutically reversible CMV-associated encephalopathy during radiotherapy of the brain
Conclusion
CMV reactivation frequently causes encephalopathy during radio(chemo)therapy of the brain. The unexpected high incidence of this infection makes it highly clinically relevant for every treating physician. (Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Goerig, N. L., Frey, B., Korn, K., Fleckenstein, B., Überla, K., Schmidt, M. A., Dörfler, A., Engelhorn, T., Eyüpoglu, I., Rühle, P. F., Putz, F., Semrau, S., Gaipl, U. S., Fietkau, R. Tags: Clinical Investigation Source Type: research
Neurocognitive function varies by IDH1 genetic mutation status in patients with malignant glioma prior to surgical resection
Conclusion.
Patients with IDH1-WT show reduced NCF compared with those with IDH1-M malignant gliomas. Lesion volume is inversely associated with NCF for patients with IDH1-WT, but not IDH1-M tumors. These findings are consistent with the hypothesis that patients with IDH1-WT tumors present with more severe NCF impairment due to greater lesion momentum, which may impede compensatory neuroplasticity and cerebral reorganization. (Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Wefel, J. S., Noll, K. R., Rao, G., Cahill, D. P. Tags: Clinical Investigations Source Type: research
Electrophysiology of glioma: a Rho GTPase-activating protein reduces tumor growth and spares neuron structure and function
Conclusions
Our findings demonstrate that CNF1 reduces glioma volume while at the same time maintaining the physiological and structural properties of peritumoral neurons. These data indicate a promising strategy for the development of more effective antiglioma therapies. (Source: Neuro-Oncology)
Source: Neuro-Oncology - November 8, 2016 Category: Cancer & Oncology Authors: Vannini, E., Olimpico, F., Middei, S., Ammassari-Teule, M., de Graaf, E. L., McDonnell, L., Schmidt, G., Fabbri, A., Fiorentini, C., Baroncelli, L., Costa, M., Caleo, M. Tags: Basic and Translational Investigation Source Type: research
